Caecum OX40+CD4 T-cell subset associates with mucosal damage and key markers of disease in treated HIV-infection
Background Blood OX40-expressing CD4 T-cells from antiretroviral (ART)-treated people living with HIV (PWH) were found to be enriched for clonally-expanded HIV sequences, hence contributing to the HIV reservoir. OX40-OX40L is also a checkpoint regulator of inflammation in…
DOI: 10.1016/j.jmii.2023.08.011