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Research papers published in 2005

Browse publicly accessible academic documents published in 2005.

3227 documents

A 4'-Phosphopantetheinyl Transferase Mediates Non-Ribosomal Peptide Synthetase Activation in Aspergillus fumigatus

Neville, Claire · Murphy, Alan · Kavanagh, Kevin + 1 author

2005Publisher: Wiley-VCH Verlag GmbH & Co.Repository: mural.maynoothuniversity.ie

Aspergillus fumigatus is a significant human pathogen. Non-ribosomal peptide (NRP) synthesis is thought to be responsible for a significant proportion of toxin and siderophore production in the organism. Furthermore, it has been shown that 4'-phosphopantetheinylation is required…

The expression of selected non-ribosomal peptide synthetases in Aspergillus fumigatus is controlled by the availability of free iron

Reiber, Kathrin · Reeves, Emer P. · Neville, Claire M. + 4 authors

2005Publisher: Elsevier B.V.Repository: mural.maynoothuniversity.ie

Three non-ribosomal peptide synthetase genes, termed sidD, sidC and sidE, have been identified in Aspergillus fumigatus. Gene expression analysis by RT-PCR confirms that expression of both sidD and C was reduced by up to 90% under iron-replete conditions indicative of a likely…

DOI: 10.1016/j.femsle.2005.05.028

Identification, cloning, and functional expression of three glutathione transferase genes from Aspergillus fumigatus

Burns, Claire · Geraghty, Rachel · Neville, Claire + 3 authors

2005Publisher: Elsevier Inc.Repository: mural.maynoothuniversity.ie

Analysis of the genome of the human pathogen, Aspergillus fumigatus, revealed the presence of several putative glutathione transferase (GST) open reading frames. Three A. fumigatus GST genes, termed gstA, B, and C, were cloned and recombinant proteins expressed in Escherichia…

DOI: 10.1016/j.fgb.2005.01.001

State, Competition and Industrial Change in Ireland 1991-1999

Ó Riain, Seán

2005Publisher: Economics and Social Studies, DublinRepository: mural.maynoothuniversity.ie

As job losses increased rapidly in 2003 amid calls for increased competitiveness, it becomes all the more crucial to understand the character and causes of such industrial upgrading that did occur in Ireland in the 1990s. This paper argues that despite a continuing reliance on…

Long-Run Cash-Flow and Discount-Rate Risk in the Cross-Section of US Returns

Panopoulou, Ekaterini · Koubouros, Michail · Malliaropulos, Dimitrios

2005Repository: mural.maynoothuniversity.ie

This paper decomposes the overall market (CAPM)risk into parts reflecting uncertainty related to the long-run dynamic of portfolio-specific and market cash flows and iiscount rates. We decompose market betas into four sub-betas (associated with assets' and market's cash flow and…

The Welfare Implications of Growth Regressions

O'Neill, Donal

2005Repository: mural.maynoothuniversity.ie

Regressions relating the growth rate in income to initial income have been the soruce of much recent debate in growth economics. recent reserch has empasised the importance of allowing for non-linearities in these models when explaining the evolution of income over time. In this…

When does 'All Eggs in One Risky Basket' Make Sense?

Boyle, Gerry · Coniffe, Denis

2005Repository: mural.maynoothuniversity.ie

: In an important paper comparing expected utility and mean-variance analysis, Feldstein (1969) examined a simple portfolio problem involving just two assets, one riskless and one risky. He concluded there could easily be plunging, that is, investment in the risky asset alone…

Integration at cost: Evidence from volatility impulse response functions

Panopoulou, Ekaterini · Pantelidis, Theologos

2005Repository: mural.maynoothuniversity.ie

We investigate the international information transmission between the U.S. ant the rest of the G-7 counteries using daily stock market return data covering the last 20 years. Apre-1995 and post-1995 analysis reveals that the linkage between the markets have changed substantially…

Income Volatility and Residential Mortgage Delinquency: Evidence from 12EU Countries

Diaz-Serrano, Luis

2005Repository: mural.maynoothuniversity.ie

We Investigate the socio-economic determinants of mortgage delinquency in 12EU countries and observe that income volatility in income is high enough. From this result we can draw the following conclusions:i) mortgage protection insurance policies might be failing to cover those…

Heterogeneour Homebuyers, Mortage Choice and the Use of Mortage Brokers.

Roche, Maurice · Duffy, David

2005Repository: mural.maynoothuniversity.ie

Choosing a mortgage product in the face of labor income risk, interest rate risk and borrowing constraints is one of the most important decisions facing a household. This paper investigates the choice between a variety of fixed rate mortgages and adjustable rate mortgages. We…

The equity premium puzzle and decreasing relative risk aversion

Roche, Maurice

2005Repository: mural.maynoothuniversity.ie

Agents are assumed to have a power risk aversion utility function in an otherwise standard asset pricing model. These preferences are shown to be capable of eliminating one version of the equity premium and risk free rate puzzles when they display decreasing relative risk…

Declining Discount Rates: Evidence from the UK

Groom, Ben · Koundouri, Phoebe · Panopoulou, Ekaterini + 1 author

2005Repository: mural.maynoothuniversity.ie

We estimate schedules of declining discount rates for cost benefit analysis in the UK. We highlight the importance of model selection for this task and hence for the evaluation of long-term investments, namely climate change prevention and uuclear build.

Enantioselective separation of the sunscreen agent 3-(4-methylbenzylidene)-camphor by electrokinetic chromatography: Quantitative analysis in cosmetic formulations

Gómara Moreno, Belén · García Ruiz, Carmen · Marina Alegre, María Luisa

2005Publisher: John Wiley & SonsRepository: e_Buah — Universidad de Alcalá

Authors thank the Ministry of Science and Technology (Spain) for the research project BQU2003-03638. C.G.-R. thanks the Ministry of Science and Technology for the Ramón y Cajal program (RYC-2003-001). B.G. thanks CSIC and the RYC-2003-001 project for the grants. Authors also…

DOI: 10.1002/elps.200500080

Separation of etodolac enantiomers by capillary electrophoresis. Validation and application of the chiral method to the analysis of commercial formulations

Rodríguez de Pablos, Raquel · García Ruiz, Carmen · Crego Navazo, Antonio Luis + 1 author

2005Publisher: John Wiley & SonsRepository: e_Buah — Universidad de Alcalá

Separation of etodolac enantiomers, which exhibit different biological activity and pharmacokinetic profiles, has been achieved using the randomly substituted (2-hydroxy)propyl-β-cyclodextrin (HP-β-CD) as chiral selector in capillary electrophoresis. The selection of this CD was…

DOI: 10.1002/elps.200410097

Detection and quantitation of additions of soybean proteins in cured-meat products by perfusion reversed-phase high-performance liquid chromatography

Criado, Mónica · Castro Rubio, Florentina · García Ruiz, Carmen + 2 authors

2005Publisher: John Wiley & SonsRepository: e_Buah — Universidad de Alcalá

The authors thank the Comunidad Autónoma de Madrid (Spain) for project 07G/0025/2003. Dr. C. García-Ruiz also thanks the Ministerio de Ciencia y Tecnolog a for her contract from the Ramón y Cajal program (RYC-2003-001). F. Castro-Rubio thanks the Ministerio de Educación y…

DOI: 10.1002/jssc.200500011

MtDNA diversity among four Portuguese autochthonous dog breeds: a fine-scale characterisation

Van Asch, B · Pereira, L · Pereira, F + 3 authors

2005Publisher: BioMed CentralRepository: Repositório Aberto — Universidade do Porto

BACKGROUND: The picture of dog mtDNA diversity, as obtained from geographically wide samplings but from a small number of individuals per region or breed, has revealed weak geographic correlation and high degree of haplotype sharing between very distant breeds. We aimed at a…

Onset detection using Comb Filters

Gainza, Mikel · Coyle, Eugene · Lawlor, Bob

2005Publisher: Institute of Electrical and Electronics EngineersRepository: mural.maynoothuniversity.ie

A technique for detecting note onsets using FIR comb filters which have different filter delays is presented. The proposed onset detector focuses on the inharmonic characteristics of the onset component and the energy increases of the signal. Both properties are combined by…