A 4'-Phosphopantetheinyl Transferase Mediates Non-Ribosomal Peptide Synthetase Activation in Aspergillus fumigatus
Aspergillus fumigatus is a significant human pathogen. Non-ribosomal peptide (NRP) synthesis is thought to be responsible for a significant proportion of toxin and siderophore production in the organism. Furthermore, it has been shown that 4'-phosphopantetheinylation is required…