Table 1: NHANES 2007-2012 cha ac e is ics o he o al s udy popula ion, and s a i ied by
as hma diagnosis
O e all
Popula ion
As hma ics
Non-as hma ic
con ols
p
N=18,319
N=1,584 (8.6%)
N=16,735
(91,4%)
Age (yea s), mean (SD)
Child en (<18) (n, %)
Adul s (18–65) (n, %)
Elde ly (>65) (n, %)
36.3 (20.9)
4825 (26.3)
11556 (63.1)
1938 (10.6)
32.7 (20.8)
6998 (57.7)
3009 (24.8)
2116 (17.5)
36.7 (20.8)
11823 (38.8)
14565 (47.8)
4054 (13.3)
<0.001
Female, n (%)
8954 (48.9%)
891 (56.2%)
8063 (48.2%)
<0.001
BMI (kg/m2), mean (SD)
26.9 (7.4)
28.1 (8.7)
26.8 (7.2)
<0.001
E hnici y, n (%)
Mexican Ame ican
O he Hispanic
Non-Hispanic Whi e
Non-Hispanic Black
O he Race - Including Mul i-Racial
3357 (18.3%)
2014 (11.0%)
7322 (40.0%)
4006 (21.9%)
1620 (8.8%)
161 (10.2%)
182 (11.5%)
655 (41.4%)
466 (29.4%)
120 (7.6%)
3196 (19.1%)
1832 (10.9%)
6667 (39.8%)
3540 (21.2%)
1500 (9.0%)
<0.001
Medica ion
ICS use (n, %)
ICS/LABA use (n, %)
OCS use (n, %)
OCS/ICS use in las 2 days (n, %)
408 (2.2%)
239 (1.3%)
183 (1.0%)
724 (4.0%)
344 (21.8%)
202 (12.8%)
57 (3.6%)
481 (30.4%)
64 (0.4%)
37 (0.2%)
126 (0.8%)
243 (1.5%)
<0.001
<0.001
<0.001
<0.001
Smoking his o y
Ne e smoke s (n, %)
Ex-Smoke s (n, %)
Cu en Smoke s (n, %)
12431 (67.9%)
2959 (16.2%)
2929 (16.0%)
1081 (68.2%)
236 (14.9%)
267 (16.9%)
11350 (67.8%)
2723 (16.3%)
2662 (15.9%)
0.273
Spi ome y
Baseline FEV1 (L), mean (SD)
Baseline FEV1pp, median (IQR)#
Baseline FEV1/FVC, mean (SD)
2.87 (0.92)
89.7 (76, 100)
0.81 (0.1)
2.78 (0.95)
80.7 (67, 93)
0.78 (0.1)
2.88 (0.92)
90.4 (77, 101)
0.81 (0.1)
0.163
<0.001
<0.001
Type-2 bioma ke s
FeNO, mean ppb (SD)
BEC, mean cells/μL (SD)
13 (8-20)
211 (190)
15 (8.5-28.5)
280 (230)
12.5 (8-20)
210 (190)
<0.001
<0.001
Abb e ia ions: SD: S anda d De ia ion, BMI: Body Mass Index, ICS: Inhaled Co icos e oids, LABA: Long-
Ac ing Be a-2 Agonis s, OCS: O al Co icos e oids, FEV1: Fo ced Expi a o y Volume in 1 second, FEV1pp:
pe cen o p edic ed Fo ced Expi a o y Volume in 1 second, FVC: Fo ced Vi al Capaci y, FeNO: F ac ional
Exhaled Ni ic Oxide, BEC: Blood Eosinophil Coun s, s a is ically signi ican di e ences be ween as hma ics
and pa icipan s wi hou as hma a e highligh ed in bold. #FEV1 pe cen o p edic ed alues we e calcula ed
using he Hankinson- o mula
