Funded by he Eu opean Union unde he G an Ag eemen 101091464. Views and opinions exp essed a e
howe e hose o he au ho (s) only and do no necessa ily e lec hose o he Eu opean Union o Eu opean
Heal h and Digi al Execu i e Agency (HaDEA). Nei he he Eu opean Union no he g an ing au ho i y can be held
esponsible o hem.
Sus ainable su ace p o ec ion by glass-like
hyb id and bioma e ials coa ings
Deli e able D.6.3
Da a Managemen Plan
Deli e able In o ma ion
Responsible pa ne :
7P9-SI
Wo k package No and
Ti le:
WP6 - Da a Managemen Plan
Con ibu ing pa ne (s):
7P9-DE
Dissemina ion le el1:
PU
Type:
R
Due da e:
30/06/2023
Submission da e:
30/06/2023
Ve sion:
V2
1
PU = PUBLIC ully open ((wa ning) au oma ically pos ed online on he P ojec Resul s pla o ms)
SEN = Sensi i e — limi ed unde he condi ions o he G an Ag eemen
EUCl = EU classi ied unde Decision 2015/444
Re . A es(2023)4548311 - 30/06/2023
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D.6.3: Da a Managemen Plan
P ojec P o ile
P og amme
Ho izon Eu ope
Call
HORIZON-CL4-2022-RESILIENCE-01
Topic
HORIZON-CL4-2022-RESILIENCE-01-23: Sa e and sus ainable by design
chemicals and ma e ials (RIA)
Numbe
101091464
Ac onym
BIO-SUSHY
Name
Sus ainable su ace p o ec ion by glass-like hyb id and bioma e ials coa ings
S a Da e
1 Janua y 2023
Du a ion
48 mon hs
Type o ac ion
HORIZON Resea ch and Inno a ion Ac ions
G an ing au ho i y
Eu opean Heal h and Digi al Execu i e Agency
P ojec Coo dina o
MATERIA NOVA
Documen His o y
Ve sion
Da e
En i y
Rema ks
V1
8 June 2023
7P9-SI, 7P9-DE
Fi s d a
V2
26 June 2023
MANO, SIK, ZSI, AXIA,
RESCOLL, CNR, PQSAR,
WOODK+
Pa ne inpu
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D.6.3: Da a Managemen Plan
Publishable Summa y
This deli e able epo desc ibes he c ea ion o he BIO-SUSHY Resea ch Ou pu Managemen Plan
(ROMP) as an ex ension o a Da a Managemen Plan (DMP) and con ains he i s e sion as Annex I.
Wi h he success o he FAIR p inciples o os e making mo e and mo e da a a ailable o e-use, i
became ob ious ha he high-quali y knowledge managemen app oaches should also be applied o
o he esea ch ou pu s o inc ease hei e-usabili y. To spea head such a comp ehensi e app oach,
BIO-SUSHY has s a ed o go beyond he DMP, manda o y o all p ojec s o he Ho izon Eu ope
F amewo k P og amme, by co e ing all esea ch ou comes including bu no limi ed o da a,
p o ocols, models, so wa e, su eys and esponses, epo s and publica ions in he ROMP and
speci ying common managemen ecommenda ions and guidelines ac oss all esea ch ou pu s as
well as speci ic app oaches and ooling o indi idual ypes. To be able o co e he equi emen s o
all ou pu ypes, BIO-SUSHY, in collabo a ion wi h he MACRAMÉ p ojec (EU Ho izon Eu ope esea ch
and inno a ion p og amme, g an ag eemen No. 101092686), pe o med an e alua ion o exis ing
DMP empla es p oposed in he DMPonline, DS Wiza d and ARGOS ools. None o hem is p o iding
all unc ionali y and lexibili y needed by BIO-SUSHY, especially wi h espec o co e ing
compu a ional me hods and esea ch so wa e. Thus, he BIO-SUSHY ROMP was newly designed by
s a ing om he s uc u e o he ARGOS ools, ans e ing sec ions o he o he ools o s eng hen
speci ic aspec s and adding addi ional sec ions based on he FAIR o Resea ch So wa e (FAIR4RS),
TRUST and CARE da a guidance p inciples.
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D.6.3: Da a Managemen Plan
Table o Con en s
Publishable Summa y .................................................................................................................................. 3
Lis o Figu es ................................................................................................................................................ 5
Table o Abb e ia ions ................................................................................................................................. 6
1. Objec i es .............................................................................................................................................. 8
2. C ea ion o he i s e sion o he Resea ch Ou pu Managemen Plan (ROMP) ........................... 8
3. BIO-SUSHY da a managemen in as uc u e ................................................................................. 10
4. Conclusions ........................................................................................................................................ 11
5. Re e ences .......................................................................................................................................... 12
6. Annexes .............................................................................................................................................. 13
Annex I: Ini ial Ve sion o he BIO-SUSHY Resea ch Ou pu Managemen Plan (ROMP) ................ 13
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D.6.3: Da a Managemen Plan
Lis o Figu es
Figu e 1: Da a managemen concep in which all da a om expe imen , compu a ional app oaches
and public esou ces is in eg a ed o build he da a lake used as inpu o da a-d i en modelling o
guide he SSbD decisions o he de elopmen o he new coa ings as well as o p epa e upload o
public da abases) ...................................................................................................................................... 11
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D.6.3: Da a Managemen Plan
Table o Abb e ia ions
Abb e ia ion
De ini ion
EU
Eu opean Union
EC
Eu opean Commission
H2020
Ho izon 2020 esea ch and inno a ion p og amme
HE
Ho izon Eu ope esea ch and inno a ion p og amme
WP
Wo k Package
PFAS
Pe - and poly luo ina ed alkyl subs ance
DMP
Da a Managemen Plan
ROMP
Resea ch Ou pu Managemen Plan
RO
Resea ch Ou pu
TBD
To Be De ined
FAIR
Findable, Accessible, In e ope able and Re-usable (da a guidance p inciples)
FAIR4RS
FAIR o Resea ch So wa e
FIP
FAIR Implemen a ion P o ile
FER
FAIR Enabling Resou ce
FSR
FAIR Suppo ing Resou ce
TRUST
T anspa ency, Responsibili y, Use ocus, Sus ainabili y, and Technology (da a
guidance p inciples)
CARE
Collec i e bene i , Au ho i y o con ol, Responsibili y, and E hics (da a guidance
p inciples)
GDPR
EU’s Gene al Da a P o ec ion Regula ion
DOI
Digi al Objec Iden i ie
ORCID
Open Resea che and Con ibu o ID
ROR
Resea ch O ganisa ion Regis y (iden i ie )
ERM
Eu opean Regis y o Ma e ials (iden i ie )
CAS
Chemical Abs ac Se ice Regis y Numbe
IUPAC
In e na ional Union o Pu e and Applied Chemis y
InChI
IUPAC In e na ional Chemical Iden i ie
ELIXIR
Eu opean li e sciences in as uc u e
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D.6.3: Da a Managemen Plan
TeSS
ELIXIR T aining eSuppo Sys em
SOP
S anda d Ope a ing P ocedu e
SSbD
Sa e-and-Sus ainable-by-Design
MODA
MOdelling DA a epo ing o ma
CHADA
CHa ac e isa ion DA a epo ing o ma
QSAR
Quan i a i e S uc u e Ac i i y Rela ionship
QMRF
QSAR Model Repo ing Fo ma
QPRF
QSAR P edic ion Repo ing Fo ma
API
Applica ion P og amming In e ace
EOSC
Eu opean Open Science Cloud
OECD
O ganisa ion o Economic Co-ope a ion and De elopmen
VAMAS
Ve sailles P ojec on Ad anced Ma e ials and S anda ds
ISO
In e na ional O ganiza ion o S anda diza ion
CEN
Eu opean Commi ee o S anda diza ion
ECHA
Eu opean Chemicals Agency
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D.6.3: Da a Managemen Plan
1. Objec i es
As a pa o i s open science philosophy, BIO-SUSHY is implemen ing high-quali y knowledge and
da a managemen wi h he goals o acili a e, ha monise and accele a e in o ma ion sha ing wi hin
he p ojec and, a he same ime, p epa e all BIO-SUSHY esea ch ou pu o open and FAIR ( indable,
accessible, in e ope able, and e-usable) elease. One impo an ool o o ganise da a collec ion,
documen a ion, p ese a ion and p epa a ion o sha ing is he Da a Managemen Plan (DMP). I is
he cen al guidance documen o he conso ium speci ying, i s , he ypes o da a o be gene a ed
wi hin he p ojec and wha da a managemen concep s, app oaches and ools a e ecommended
and, in subsequen e sions, is p o iding mo e and mo e in o ma ion on he da a p oduced (da a
o ma s, size), applied (me a)da a s anda ds, anno a ions and solu ions o long- e m s o age and
indexing. Due o his cen al ole, he DMP is now manda o y o p ojec s unded unde Ho izon
Eu ope. Howe e , BIO-SUSHY is going e en one s ep u he . Al eady du ing he p oposal w i ing, he
conso ium ag eed ha i will apply he high-quali y managemen s anda ds no only o da a bu o
all esea ch ou pu s and will documen hese in he Resea ch Ou pu Managemen Plan (ROMP),
which in eg a es and ex ends he DMP. This was seen as necessa y o be able o clea ly documen all
s eps in he de elopmen , p oduc ion and sa e y and sus ainabili y e alua ion o he new coa ings.
Since many no el and non-s anda d me hods a e used in BIO-SUSHY, de ailed and comple e
documen a ion o he design p ocess, p ocedu es (me hod desc ip ions, p o ocols, s anda d
ope a ing p ocedu es), p ocessing, analysis and ex ac ed e idence and conclusions ha e o be
p o ided as (me a)da a o unde s and and e alua e all po en ial in luences on he esul s.
Addi ionally, he s ong in eg a ion o physics-based and da a-d i en modelling and simula ions
ex ends he ypes o esea ch ou pu s o be co e ed o compu a ional models, wo k lows and
so wa e.
To de elop he bes way o guide he conso ium in he ask o documen ing all hese esea ch
ou pu s and selec ing app op ia e app oaches, BIO-SUSHY was collabo a ing wi h he MACRAMÉ
p ojec o c ea e he s uc u e o he ROMP. Besides he comple e adop ion o he open science and
FAIR guidance p inciples1, add essing equi emen s o speci ic o he esea ch ou pu s and
in eg a ing aspec s such as quali y assu ance, esponsibili y, us wo hiness and e hics we e majo
objec i es o he ROMP de elopmen . To achie e hese, da a managemen was comple ely aligned
wi h BIO-SUSHY’s o e all quali y and isk managemen (see Deli e able D6.2) and he FAIR o
Resea ch So wa e (FAIR4RS)2, TRUST3 and CARE4 p inciples, besides he newes ecommenda ions
om he Wo ldFAIR p ojec and he GO FAIR A ancedNano Implemen a ion Ne wo k, we e
conside ed.
2. C ea ion o he i s e sion o he Resea ch Ou pu
Managemen Plan (ROMP)
As in oduced abo e, de ails o and guidance on he adop ed managemen p inciples, FAIRi ica ion
app oaches, da a secu i y and e hics conside a ions as ag eed on by he conso ium a e documen ed
in he Resea ch Ou pu Managemen Plan (ROMP) as an ex ended e sion o a Da a Managemen
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D.6.3: Da a Managemen Plan
Plan (DMP) co e ing no only da a bu also all o he ou pu s including bu no limi ed o p o ocols,
models, so wa e, su eys and esponses, epo s and publica ions. I is designed as a li ing
documen being upda ed cons an ly du ing he un ime o he p ojec and is p o ided in i s i s
e sion as Annex I o his epo . Besides he ini ial e sion p esen ed he e, we an icipa e ha a leas
wo addi ional s able e sions o he plan (in e media e and inal) will be compiled and publicly
sha ed o accommoda e epo ing o he da a gene a ion a he mid e m and end o he p ojec bu
also o be able o adap o he as -changing ield o Open and FAIR da a in Eu ope.
Acco ding o he EC ecommenda ion o make da a indable, accessible, in e ope able and e-usable
(FAIR), a Da a Managemen Plan and, hus, also i s ex ension, he ROMP, includes in o ma ion on he
ollowing de ails:
1. Handling o esea ch ou pu s (RO) du ing & a e he end o he P ojec ;
2. Wha RO a e collec ed, p ocessed and/o gene a ed;
3. Which me hodology and s anda ds a e applied;
4. Whe he RO a e sha ed/made Open Access;
5. How RO a e cu a ed and p ese ed (including a e p ojec end).
The ini ial e sion o he BIO-SUSHY ROMP mainly documen s decisions made by he conso ium and
guidelines o be implemen ed by he da a p o ide s and he da a manage s in collabo a ion wi h and
unde he supe ision o he BIO-SUSHY da a shephe d. This will subsequen ly be complemen ed
h oughou he p ojec wi h speci ic in o ma ion on he esea ch ou pu s gene a ed and esou ces
e-used in he p ojec as well as upda es and e inemen s o he used FAIR Enabling and Suppo ing
Resou ces (FERs and FSRs) and imp o emen s in ha monisa ion and in e ope abili y. Thus, he ROMP
has, as al eady s a ed abo e, o be unde s ood as a li ing documen , in which changes a e clea ly
acked o show addi ions as well as decisions, which had o be changed, e ised o eplaced as a
eac ion o eme ging new s anda ds, ools and guidelines. In cases whe e he con en o he
documen needs mo e ex ensi e adap a ions o a speci ic ype o esea ch ou pu , a speci ic sec ion
o his ype will be added o e en a speci ic ROMP o his ype will be c ea ed and e e ed o in his
gene al ROMP co e ing he p ojec globally.
Fo c ea ing he ROMP, h ee di e en online DMP ools we e e alua ed acco ding o c i e ia ha
e alua e i hey co e ed all necessa y aspec s and p o ided he app op ia e s uc u e needed o
de ine he managemen app oach and he gene alisa ion o all esea ch ou pu in close collabo a ion
wi h he MACRAMÉ p ojec . The ools e alua ed a e:
1. DMPonline om he Digi al Cu a ion Cen e,
2. DS Wiza d and
3. ARGOS.
Resul s o his e alua ion ha e al eady been desc ibed in he public deli e able D3.1 o he MACRAMÉ
p ojec , which is cu en ly s ill unde e iew by he Eu opean Commission. The e o e, we will
ep oduce hem he e again and wan o s ess he impo ance co e ing compu a ional models,
wo k lows, and so wa e as speci ic esea ch ou pu s in he ROMP. This was a speci ic equi emen
o BIO-SUSHY because o he much mo e cen al ole o physics-based and da a-d i en modelling
and simula ion app oaches compa ed o MACRAMÉ.
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D.6.3: Da a Managemen Plan
1.1.2 Is i physical o digi al?
This ROMP co e s he digi al objec s gene a ed o e-used in BIO-SUSHY. I equi ed, physical objec s
p oduced by he p ojec and managed using speci ic cen alised and s anda dised esou ces (e.g.
e e ence ma e ial eposi o ies, biobanks) will be add essed in a speci ic ROMP on physical objec s
aligned o he ROMP on digi al objec s p esen ed he e as much as possible.
1.1.3 A e you gene a ing o e-using i ?
Digi al esea ch objec s a e gene a ed as pa o he BIO-SUSHY coa ing de elopmen s and SSbD
e alua ion. These a e complemen ed by da a and accompanying me ada a mined and cu a ed om
public da abases and scien i ic li e a u e. Addi ionally, exis ing compu a ional models, wo k lows and
so wa e will be e-used o simula ing molecula in e ac ions and p edic ing physicochemical
cha ac e is ics, unc ionali y, and human heal h and en i onmen al sa e y.
1.1.4 Wha is he ype o he desc ibed esea ch ou pu ?
As desc ibed abo e, his ROMP co e s all esea ch ou pu om BIO-SUSHY. I can be g ouped in o
he ollowing gene al ca ego ies (mo e speci ic ca ego ies will be added du ing he con inuous
upda ing o his li ing documen ), which is used (including numbe ing) o he u he s uc u ing o
he answe s in his ROMP:
1. S udy designs
2. Me hod speci ica ions
a.
expe imen al
b.
compu a ional
3. P o ocols / SOPs
4. Compu a ional models
5. So wa e and compu a ional wo k lows
6. Da a
7. Su eys and su ey esponses
8. Guidelines
9. Repo s and knowledge collec ions
10. T aining ma e ials
a. Manuals / u o ials
b. Videos
c. Handbooks / e e ence ma e ial
11. Publica ions
a. Dissemina ion ma e ial
b. Whi e pape s
c. Pee - e iewed pape s
1.1.5 Wha is i s o ma ?
The a ie y o esea ch ou pu ypes lis ed abo e clea ly shows ha i is no possible o co e all o
hem in one exchange o ma . Addi ionally, di e en BIO-SUSHY pa ne s en e ed he p ojec wi h
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D.6.3: Da a Managemen Plan
e y di e en knowledge managemen app oaches applied in hei in e nal p ocesses and
wo k lows, which ha e o be conside ed when c ea ing he ecommenda ions o p ojec -wide da a
managemen and public sha ing. The e o e, his ini ial ROMP lis s all da a o ma s cu en ly in use
and uses he (me a)da a epo ed in hese o ma s o de elop ecommenda ions o imp o emen
o he da a managemen p ac ices a speci ic pa ne s, selec app op ia e FAIRi ica ion ools o each
se ing, and de elop (semi-)au oma ed app oaches o ansla e in e nal o ma s in o ha monised
and in e ope able da a documen a ion o ma s aligned wi h communi y and egula o y s anda ds.
1.
S udy designs
: ins ance maps
2.
Me hod speci ica ions
: ex documen s, da a empla es (MODA, CHADA)
3.
P o ocols / SOPs
: ex documen s, elec onic lab no ebooks
4.
Compu a ional models:
da a empla es (QMRF, QPRF, MODA)
5.
So wa e and wo k lows
: da a empla es (QMRF, QPRF, MODA), no ebooks (jupy e , colab), API
de ini ions.
6.
Da a
: cus omised sp eadshee s, da a empla es (nanoFASE, eNanoMappe , MODA, CHADA),
p op ie a y o ma s, da a se ialisa ion o ma s (json, yaml)
7.
Su eys and su ey esponses:
ex documen s, sp eadshee s, Google o ms
8.
Guidelines
: ex documen s
9.
Repo s
: ex documen s
10.
T aining ma e ials
: ex documen s, slides, ideos
11.
Publica ions
: ex documen s
1.1.6 Wha is i s expec ed size?
Limi ed in o ma ion on expec ed size is a ailable a he cu en s a e. Simila p ojec s had ela i ely
low equi emen s o da a s o age capaci ies. Howe e , he dis ibu ed da a s o age app oach
adop ed by BIO-SUSHY will also be able o co e much highe demands i necessa y. This can be
achie ed by e.g. s o ing la ge aw da a iles only locally a he da a p o ide s o using da a s o ing
solu ions specialised o a speci ic da a ype (e.g. omics) o o gene al s o age o big da a as e.g.
p o ided by he Eu opean Open Science Cloud (EOSC).
1.1.7 Why a e you collec ing/gene a ing o e-using i ?
Da a is p ima ily gene a ed and collec ed o e-use o sa is y he da a needs o he BIO-SUSHY
coa ing de elopmen in he h ee use cases including unc ionali y and SSbD e alua ion. The
expe imen al and compu a ional da ase s will hen be p o ided o guide de ining SSbD c i e ia o
coa ings and, subsequen ly, as inpu o he s anda disa ion and egula o y alida ion p ojec
ini ia ed a he ele an bodies (e.g. OECD, VAMAS, ISO, CEN).
1.1.8 Wha is i s o igin / p o enance?
Each esea ch ou pu , bo h gene a ed by BIO-SUSHY and collec ed om hi d pa ies, will speci ically
documen i s o igin and p o enance as pa o he se o s anda dised me ada a.
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D.6.3: Da a Managemen Plan
1.1.9 To whom migh i be use ul (“da a u ili y”)?
P ima y use s o he da a will be he BIO-SUSHY conso ium pa ne s pe o ming he de elopmen
and op imisa ion as well as SSbD e alua ion on he use case coa ings. Seconda y use s will hen be
de elope s o SSbD c i e ia o bio-based and hyb id coa ing ma e ials as well as labs (academia and
indus y) in e es ed in pe o ming Sa e-and-Sus ainable-by-Design (SSbD) ma e ial de elopmen .
The da a will hen also be made a ailable o s a ing he s anda disa ion and egula o y alida ion
p ojec s o in eg a ing speci ic SSbD c i e ia o coa ings suppo ing egis a ion o such new
ma e ials.
2 Links Be ween Ou pu s
2.1 Publica ions
2.1.1 Does he desc ibed ou pu suppo any scien i ic publica ion?
Due o he ecen p ojec s a , BIO-SUSHY has no ye p oduced scien i ic publica ions suppo ed by
he newly gene a ed esea ch ou pu s. Fo da a collec ed and mined om da abases and li e a u e,
he co esponding e e ences a e s o ed as me ada a p o iding clea p o enance ails o he
ex ac ed in o ma ion.
2.1.2 Is he e a da a a ailabili y s a emen p o ided along wi h he publica ion?
Da a a ailabili y s a emen s will be p o ided in all u u e publica ions esul ing om he BIO-SUSHY
p ojec . These will include unique, pe sis en iden i ie s (DOIs o da a-speci ic iden i ie s), licensing
in o ma ion, clea p o enance ails, and e e ences o he da a models used i applicable.
2.2 Quali ied e e ences o o he objec s
2.2.1 Does he desc ibed ou pu suppo any o he esea ch ou pu ?
BIO-SUSHY has adop ed he app oach o p o iding he di e en esea ch ou pu ypes as indi idual
esou ces. Ins ead o c ea ing complex (me a)da a empla es s o ing in o ma ion on he me hods,
p o ocols and he gene a ed aw and p ocessed da a, as e.g. implemen ed in he NIKC-NanoFASE
empla es o he MODA/CHADA sys em, all hese componen s a e managed using indi idual ools
cus omised and op imised o each ype (e.g. elec onic lab no ebooks, me hod-speci ic da a o ma s
and da abases, e sion con ol sys ems). Howe e , his esul s in he ac ha many esea ch ou pu s
a e needed o p o ide all in o ma ion a speci ic piece o e idence o conclusion is based on.
Managing all esea ch ou pu using he ha monised app oach desc ibed in his ROMP has he
ad an age ha all di e en ypes can be handled indi idually and, a he same ime, ou pu s
suppo ing each o he can be linked oge he gi ing ull access o all in o ma ion ele an o e.g. a
speci ic me hod o a BIO-SUSHY use case. Fo example, da a include e e ences o he me hods and
p o ocols used o gene a e i as me ada a and me hods can lis all da ase used o es ing and
alida ion.
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D.6.3: Da a Managemen Plan
2.2.2 Is he esea ch ou pu in eg a ed in o a sys em o quali ied e e ences c oss-
linking ou pu s?
The concep o indi idual esou ces has he ad an age o access o op imal da a managemen ools
o each ype. Howe e , such a dis ibu ed sys em is pu ing mo e demands on keeping ack o all
he esou ces suppo ing each o he and consis ency o he esou ce e e ences since losing links
be ween he esou ces would des oy da a comple eness, unde s andabili y, in e p e abili y, and,
hus, us and ul ima ely e-usabili y. BIO-SUSHY has es ablished an ad anced sys em o esea ch
ou pu c oss-linking composed o wo se ices, he BIO-SUSHY Regis y and he ins ance map ool.
The i s assigns a unique, e en i only in e nal iden i ie o each esea ch ou pu . Addi ionally, basic
me ada a on da a p o enance and accessibili y, e e ences o use cases and p ojec pa ne s a e
p o ided. The second se ice is hen p o iding ways o build u he c oss-links be ween he esea ch
ou pu s based on he unique iden i ie s, e.g. linking p o ocols o he gene a ed da a, and o isualise
hese as ins ance maps ep esen ing li e-cycle s ages o he ma e ials and he expe imen al wo k low
o p oduc ion and assessmen . Fo public sha ing and long- e m s o age, all ele an esea ch, e.g.
suppo ing a scien i ic publica ion, can be ex ac ed om he in e nal managemen solu ion by:
● Replacing he in e nal iden i ie s au oma ically wi h global and pe sis en iden i ie s om
au ho i ies like Da aCi e/Zendo (DOIs), Eu opean Regis y o Ma e ials (ERM), ORCID,
Resea ch O ganisa ion Regis y (ROR) o public da a/p o ocol eposi o ies;
● Packing all esou ces speci ied in one ins ance map in o a da a package ollowing he
ic ionless da a o RO-C a e speci ica ions ei he as (me a)da a iles o as links o o he public
esou ces; and
● Publicly sha ing o he da a packages in FAIR da a s o ing solu ions.
2.3 P e-exis ing da a
2.3.1 A e you using any p e-exis ing esea ch ou pu ?
P e-exis ing esea ch ou pu s will be e-used in he o m o exis ing me hod desc ip ions,
p o ocols/SOPs, compu a ional models, wo k lows, and so wa e as well as da a mined and cu a ed
om public da abases and scien i ic li e a u e.
2.3.2 Is he p e-exis ing esea ch ou pu handled acco ding o his ROMP including
addi ional FAIRi ica ion i necessa y? I no , p o ide links o DMP desc ibing
he ea men o hese p e-exis ing esea ch ou pu s.
The p e-exis ing da a will be handled in he same way as newly gene a ed da a as desc ibed in his
ROMP. Addi ional da a managemen s eps will include in eg a ion in o he BIO-SUSHY Regis y,
p o ision o da a p o enance ails, and ha monisa ion o da a models and ans e o ma s.
Addi ionally, FAIRi ica ion s eps will be desc ibed he e i hey become necessa y o speci ic p e-
exis ing esou ces.
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D.6.3: Da a Managemen Plan
3 Quali y con ol, FAIR P ac ices and openness
3.1 Making esea ch ou pu s indable, including p o isions o me ada a
3.1.1. Wha ype(s) o pe sis en iden i ie (s) a e used o he desc ibed esea ch
ou pu ?
BIO-SUSHY is using an in e nal se o iden i ie s, which a e assigned by he BIO-SUSHY Regis y o , in
speci ic cases, he p ojec ’s Google Sha ed Folde , a e unique wi hin he p ojec and can be ansla ed
in o globally unique and pe sis en iden i ie s a a la e s age. In his way, he di e en ( u u e)
esea ch ou pu s can be clea ly iden i ied s a ing om he planning phase on and global uniqueness
and also indexing in he ele an iden i ie se ices is achie ed o he inal e sions o he ou pu s
mean o public sha ing and long- e m s o age. Globally unique, pe sis en iden i ie s a e cu en ly
a ailable and in eg a ed in o communi y s anda ds o :
1.
Sampling plans
: DOI (po en ially)
2.
S udy designs
: DOI (po en ially)
3.
Me hod speci ica ions
: DOI (Zenodo)
4.
P o ocols / SOPs
: DOI (Zenodo, Da aCi e)
5.
Compu a ional models, so wa e and wo k lows
: Gi Hub
6.
Da a
: DOI (Zenodo)
a.
Ma e ials:
ERM, NInChI
b.
Chemicals
: CAS, InChI, (CAS)
c.
P o ide s
: ORCID
d.
Ins i u ions
: ROR
e.
P ojec s
: DOI (EU)
7.
Su eys and su ey esponses:
DOI (po en ially)
8.
Guidelines, epo s, aining ma e ials
: DOI, TeSS
9.
Publica ions
: DOI ( om publishe )
3.1.1.1 A e componen s o he esea ch ou pu ep esen ing le els o
g anula i y (so wa e modules, expe imen al s eps, ma e ials) assigned
dis inc iden i ie s?
S udy designs, p o ocols, ma e ials/chemicals, models, wo k lows, so wa e as well as su eys and
hei esul s, epo s and publica ions a e e e ed o by indi idual iden i ie s in he in e nal sys em.
These can hus also be mapped o indi idual dis inc global iden i ie s la e . The sys em also
encou ages spli ing he expe imen al p ocedu e in o mul iple p o ocols, e.g. o sample p epa a ion,
measu emen , and p ocessing, all wi h hei own iden i ie s. Spli ing in o e en smalle pa s
(indi idual p o ocol s eps) is in p inciple also possible bu cu en ly no en isioned. This decision will
be pe iodically e iewed.
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D.6.3: Da a Managemen Plan
3.1.1.2 A e di e en e sions o he me hod desc ip ions, p o ocols, so wa e
assigned dis inc iden i ie s?
De elopmen o all esea ch ou pu s, which migh exis in di e en e sions, a e managed in
solu ions wi h au oma ic e sion con ol (Gi Hub, Google documen s). S able e sions used o
gene a e esul s o speci ic s udies will be speci ically ma ked (named e sions) and p o ided wi h
dis inc in e nal iden i ie s i s and hen global iden i ie s i hey suppo speci ic public esea ch
ou pu s.
3.1.2 Will you p o ide me ada a o he desc ibed esea ch ou pu ? Wha me ada a
will be c ea ed?
All esea ch ou pu s will be accompanied by me ada a, which will be s anda dised and made iche
o e he un ime o he p ojec . A he cu en s age, he ollowing high-le el me ada a ields a e
manda o y o all esea ch ou pu e e ed o as esou ces in he BIO-SUSHY Regis y:
1. Unique in e nal iden i ie
2. Resou ce name
3. Type o esou ce (e.g. Ma e ial, Tes me hod, p o ocol)
4. S a us (e.g. Scheduled, in p epa a ion, unde in e nal e iew)
5. Resou ce link (access pa h)
6. Sho desc ip ion
7. Con ibu o s and hei oles
8. Licence
3.1.2.1 Wha disciplina y o gene al s anda ds will be ollowed?
The inal me ada a schema o BIO-SUSHY will be composed o a che ypes, desc ibing speci ic aspec s
like con ibu o s, publica ions, (me a)da a schema, and me hod-speci ic me ada a. These a che ypes
will be cons uc ed ollowing exis ing s anda ds. Fo example, con ibu o s, ins i u ions and
publica ions will use he Da aCi e and Dublin Co e speci ica ions. Fo disciplina y componen s,
s anda ds a e cu en ly unde de elopmen o e ision (MODA/CHADA, eNanoMappe -based
empla es) and will be in eg a ed when a ailable.
3.1.2.2 In case me ada a s anda ds do no exis in you discipline, please
ou line wha ype o me ada a will be c ea ed and how.
The new p oduc ion p ocesses and es me hods de eloped in BIO-SUSHY will equi e me hod-
speci ic me ada a o ul il minimum epo ing equi emen s. These a e cu en ly unde de elopmen
based on he expe ise om ea lie p ojec s and he i s esul s p o ided by he BIO-SUSHY pa ne s.
They will be based on exis ing minimal epo ing guidelines and egula o y equi emen s bu will
p o ide he lexibili y o epo me ada a speci ic o he p ocess/me hod. To gua an ee
in e ope abili y o he highes possible ex en , he me ada a models/schemas implemen ed in he
epo ing guidelines will be p o ided as high-le el me ada a o he esea ch ou pu (da a bu also
s uc u ed in o ma ion om e.g. p o ocols, s udy designs).
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D.6.3: Da a Managemen Plan
3.1.3 Will sea ch keywo ds be p o ided in he me ada a o op imise he possibili y o
disco e y and hen po en ial e-use?
P o ision o s uc u ed (me a)da a wi h well-de ined (me a)da a schemas can be used o da a
disco e y wi hin BIO-SUSHY and po en ial e-use using ad anced sea ching/b owsing ea u es. These
will hea ily ely on he unique iden i ie s o ma e ials, me hods and p o ocols as well as seman ic
anno a ed me ada a. Addi ional ull ex sea ch will p o ide addi ional means o ind ele an
esea ch ou pu s. I his does no sa is y all needed o in o ma ion disco e y, addi ional sea ch
keywo ds will be p o ided.
3.1.4 Will me ada a be o e ed in such a way ha i can be ha es ed and indexed?
Me ada a is a ailable in a s uc u ed o ma in he BIO-SUSHY Regis y and by p o iding he
(me a)da a schemas as high-le el me ada a. Op ions on how o pe o m ha es ing and indexing will
be p o ided as pa o he me ada a accessible ia he applica ion p og amming in e aces (APIs) o
he Regis y (p ojec in e nal) and po en ially o he long- e m s o age solu ions (ex e nal).
3.2 Making esea ch ou pu s accessible
3.2.1 Reposi o y
3.2.1.1 In which eposi o y will he da ase / ou pu be deposi ed?
The esea ch ou pu is cu en ly managed and s o ed in he in e nal BIO-SUSHY Regis y and
di e en da a s o age solu ions (mainly Google Sha ed D i e). Op ions o long- e m s o age a e
cu en ly e alua ed and selec ed based on hei i ness o he speci ic ou pu and hei FAIRness
conside ing gene al solu ions like Zenodo, open ins i u ional eposi o ies, and domain-speci ic da a
wa ehouses.
3.2.1.2 Is he selec ed eposi o y a us ed sou ce?
Long- e m s o age solu ions will be selec ed based on communi y ecommenda ions a he poin o
ime. Since he esea ch ou pu is p epa ed acco ding o he high BIO-SUSHY FAIR s anda ds al eady
o in e nal da a sha ing, i will be eady o be publicly eleased a e semi-au oma ic ans o ma ion
in o he o ma eques ed by he s o age solu ion. This allows a lexible selec ion o solu ions, which
will only conside us ed sou ces, acco ding o he needs o he indi idual esea ch ou pu .
3.2.1.4 A e app op ia e a angemen s made wi h he eposi o y(ies) whe e he
desc ibed da ase will be deposi ed
A angemen s will be made when he selec ion o he long- e m s o age solu ion is inalised.
3.2.1.5 Does he eposi o y(ies) assign esea ch ou pu s wi h pe sis en
iden i ie s?
Only solu ions p o iding pe sis en iden i ie s will be conside ed in he selec ion p ocess.
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D.6.3: Da a Managemen Plan
3.2.1.7 Does he eposi o y suppo e sioning?
Only solu ions p o iding e sioning (when equi ed by a speci ic esea ch ou pu like so wa e) will
be conside ed.
3.2.2 Da a
This sec ion will be complemen ed whene e new esea ch ou pu s become a ailable since he
answe s need o be speci ic o hese ou pu s. Cu en ly, only gene al aspec s o he in e nal da a
managemen sys em (BIO-SUSHY Regis y and ins ance maps) a e gi en.
3.2.2.1 Wha is he desc ibed esea ch ou pu i le?
“BIO-SUSHY (me a)da a” (Addi ional and mo e speci ic i les will be added du ing he in eg a ion o
speci ic esea ch ou pu s.)
3.2.2.2 How is he esea ch ou pu sha ed? Speci y easons o he ype o
sha ing selec ed ( ully open, es ic ed, con iden ial) and emba go pe iod, i
applicable, sepa a ing legal and con ac ual easons om in en ional
es ic ions.
Cu en ly, all esea ch ou pu s a e only in e nally sha ed ia he BIO-SUSHY Regis y. This is he case
since none o he ou pu s ha e al eady ma u ed o hei inal e sion. When his s a us is eached
o a speci ic ou pu , sha ing decisions a e made on a case-by-case basis wi h p e e ence o ully
open sha ing and licences allowing e-use in mos si ua ions as ou lined in he conso ium
ag eemen .
3.2.2.4 Will he esea ch ou pu be accessible h ough a ee and s anda dised
access p o ocol?
Final, long- e m access will be p o ided using exis ing web-based FAIR da a solu ions wi h ee and
s anda dised access p o ocols (h p, p and speci ic API endpoin s).
3.2.2.5 A e he e any me hods o ools equi ed o access he esea ch ou pu ?
All ou pu s will be p o ided wi hou equi ing any speci ic me hods o ools o he han s anda d
applica ions (e.g. pd ). Howe e , i ele an , aw da a will be p o ided in p op ie a y o ma s since
hey o e e-use in ad anced, da a- ype-speci ic analysis so wa e.
3.2.2.8 Is he desc ibed esea ch ou pu suppo ed by a da a/ esea ch ou pu
access commi ee (e.g. o e alua e/app o e access eques s o
pe sonal/sensi i e da a)?
The BIO-SUSHY Gene al Assembly will unc ion as he esea ch ou pu access commi ee
gua an eeing ha no con iden ial da a is sha ed unau ho ised. Since no sensi i e pe sonal da a is
mean o be collec ed in BIO-SUSHY, an addi ional ex e nal commi ee is deemed non-essen ial.
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D.6.3: Da a Managemen Plan
3.2.2.9 Please speci y how he esea ch ou pu will be accessed du ing and a e
he p ojec ends especially i es ic ions a e in use.
TBD
3.2.2.10 Please speci y how long a e he p ojec has ended he esea ch
ou pu will be made accessible o .
TBD on a case-by-case basis.
3.2.2.11 How will he iden i y o he pe son accessing he da a be asce ained?
The BIO-SUSHY Regis y, ins ance map ool and he Google sha ed d i e used o empo al da a
s o age a e all p o ec ed by s a e-o - he-a au hen ica ion and au ho isa ion managemen and
accessible only a e logging in using a pe sonal accoun . In his way, asce aining and p o ocolling
he iden i y o pe sons accessing esea ch ou pu s is assu ed.
3.2.3 Me ada a
3.2.3.1. Will you p o ide me ada a e en i he desc ibed esea ch ou pu canno
be openly sha ed?
Me ada a o all esea ch ou pu s a e collec ed independen o hei inal usage and planned sha ing
op ions. This will also include in o ma ion on how o ge access o he ou pu and he pe son
esponsible o handle all eques s (see Sec ion 3.1.2 abo e).
3.2.3.2. Unde which licence will me ada a be p o ided? Speci y easons o
selec ing he licence sepa a ing legal and con ac ual easons om in en ional
es ic ions.
Me ada a will be sha ed unde he C ea i e Commons A ibu ion 4.0 License (CC-BY-4.0) i no
p ohibi ed o legal o con ac ual easons. I such cases become ele an in he u u e, he easons
will be speci ied he e.
3.2.3.3. Do me ada a p o ide in o ma ion abou how o access he desc ibed
esea ch ou pu ?
In o ma ion on he access ou es and he pe son esponsible o handling all eques s will be
p o ided as me ada a o e e y esea ch ou pu . Cu en ly, his is managed by he BIO-SUSHY egis y
p o iding links o he esou ces and esponsible pa ne s. This will be eplaced wi h in o ma ion on
long- e m s o age solu ions once he esea ch ou pu is publicly sha ed.
3.2.3.4. Do me ada a p o ide a ull desc ip ion o he da a model used o he
esea ch ou pu (including inpu and ou pu o ma s) o a link o such a
desc ip ion?
I is an icipa ed ha all esea ch ou pu s p o ide he unde lying (me a)da a model as pa o hei
high-le el da a documen a ion. This will be es ablished as pa o he addi ional FAIRi ica ion
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D.6.3: Da a Managemen Plan
ollowing he cu en ly ongoing e alua ion o he epo ing and managemen app oaches a he
indi idual BIO-SUSHY pa ne s.
3.2.3.5. Will me ada a emain a ailable a e he da ase /ou pu is no longe
a ailable?
Indexing o he me ada a in s anda d FAIR Suppo ing Resou ces like Zenodo is planned
gua an eeing a ailabili y e en a e he ou pu is no longe a ailable.
3.3 Making da a and o he ou pu s in e ope able
3.3.1 Does you (me a)da a use a con olled ocabula y?
Con olled ocabula ies will be used whene e a ailable. On one hand, he Da aModel On ology
and/o he In o ma ion A e ac On ology will be used o he high-le el da a documen a ion
including he desc ip ion and seman ic anno a ion o he (me a)da a model. On he o he hand, o
he low-le el anno a ion o me hod-speci ic me ada a, di e en on ologies like he eNM on ology,
he EMMO as well as mul iple chemical and biological on ologies a e a ailable. Howe e , i is
expec ed ha hese will no co e all ele an aspec s and BIO-SUSHY will collabo a e wi h o he
p ojec s o inc ease he on ological co e age.
3.3.2 I you c ea ed he ocabula y, whe e can i be ound?
Te minology esul ing om BIO-SUSHY’s on ology wo k will be in eg a ed in o exis ing on ologies and
will he e o e be a ailable om he se ices p o iding hese on ologies (e.g. BioPo al).
3.3.3 Ha e you applied a s anda d schema o you (me a)da a?
As desc ibed abo e, ha monisa ion has been s a ed wi h s anda disa ion o high-le el me ada a e-
using (pa s o ) exis ing s anda ds (Da aCi e, Dublin Co e). This will be complemen ed by schemas o
he me hod-speci ic (me a)da a documen ed as pa o he low-le el me ada a. These a e based on
exis ing s anda ds and minimum epo ing guidelines and he enhanced e sions c ea ed by BIO-
SUSHY (in in ensi e collabo a ion and alignmen wi h o he p ojec s) will be p oposed o
s anda disa ion.
3.3.5 Wha is he me hodology ollowed?
The ollowing concep s, pa ly al eady desc ibed in p e ious sec ions, de ine he BIO-SUSHY
me hodology:
• Indi idual managemen o esea ch ou pu s acco ding o hei ypes allows op imal selec ion o
ools o cu a ion, documen a ion and sha ing (e.g. elec onic lab no ebooks o p o ocols).
• Sepa a ion o high- (biog aphical me ada a, access op ions, licences, documen a ion o da a
model) and low-le el (me hod-speci ic me ada a) da a documen a ion p o ides in e ope abili y
and compu e -ac ionabili y o di e en applica ions (da a disco e y s. da a in eg a ion in o
compu a ional wo k lows)
