156
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE “MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
DEVELOPMENT OF A TRANSDERMAL MEDICINE FOR WOUND HEALING
Niki in K.A.
Zhilyako a E.T.
Belgo od S a e Na ional Resea ch Uni e si y, Belgo od, Russian Fede a ion
e-mail: [email p o ec ed], phone +79087895220
h ps://doi.o g/10.5281/zenodo.17328605
Rele ance: he ele ance is due o he high p e alence o wound pa hology and he lack o
complex and e ec i e means o i s ea men in he domes ic pha maceu ical ma ke .
Pu pose o he s udy: de elopmen o a ansde mal dosage o m o wound healing ac ion
Ma e ials and me hods: analy ical esea ch me hods and compu e modeling me hods we e
used in he wo k
Resul s: in o de o educe he de elopmen ime and ma e ial cos s, 8 composi ions con aining
benzyl dime hyl[3-(my is oyl amino) as an an imic obial componen we e selec ed using he Syn elly
a i icial in elligence pla o m o o ganic and medical chemis y.p opyl]ammonium (mi amis in),
xymedon, o acecsamic acid as a epa an , as well as 1 o 5 NSAIDs: ke op o en, ke o olac,
benzydamine, nimesulide, o phenylbu azone, which a e p edic ed o be s able. Th ee design op ions
o a ansde mal sys em ha e been p oposed o p o ide con olled p olonged elease. (pic .1).
Pic u e 1. Schemes o p oposed designs o ansde mal he apeu ic sys ems wi h wound-
healing e ec : ma ix (A), ese oi (B), and combined (C).
Conclusions: possible composi ions and designs o a ansde mal he apeu ic sys em ha e been
de eloped and heo e ically subs an ia ed.
А
1 - Подложка
Б
1 - Подложка
2 – Адгезив с растворенным ЛВ
2 - Резервуар с растворенным ЛВ
3 – Защитная пленка
3 - Мембрана
4 - Адгезив
5 - Защитная пленка
В
1 - Подложка
2 - Резервуар с растворенным ЛВ
3 - Мембрана
4 - Адгезив с растворенным ЛВ
5 - Защитная пленка
