201
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE “MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
STRATEGIES FOR REDUCING SIDE EFFECTS OF DRUGS IN
ONCOGEMATOLOGICAL DISEASES
Tu daliye a M.M.
Sul ano a G.A.
Tashken Pha maceu ical Ins i u e, Tashken ci y, Republic o Uzbekis an
e-mail: [email p o ec ed]
h ps://doi.o g/10.5281/zenodo.17332757
Rele ance: oncogema ological diseases, especially in child en, can cause se ious nega i e
e ec s and long- e m heal h p oblems. The side e ec s o he d ugs used o ea hese condi ions can
educe he quali y o li e o pa ien s, making he ea men p ocess mo e di icul . T ea men s such as
chemo he apy, immuno he apy, adio he apy can cause signi ican damage o child en's immune
sys em and o e all heal h. The e o e, in oncogema ological diseases, i is o u gen impo ance o
educe he side e ec s o d ugs, inc ease he e ec i eness o ea men and imp o e he quali y o
li e o pa ien s. Today, e ec i e ea men s a e needed o educe he numbe o pa ien s dying om
child en's oncogema ological diseases, bu i is always ele an o educe side e ec s and c ea e sa e
and mo e e ec i e he apy o pa ien s. This esea ch will help de elop s a egies aimed a
minimizing he nega i e e ec s o d ugs.
Pu pose o he s udy: he s udy en isages he ollowing main objec i es: o de elop s a egies
o choosing a ional d ugs o educe he side e ec s o basic ea men s such as chemo he apy and
adio he apy. Taking in o accoun gene ic and clinical cha ac e is ics when p esc ibing d ugs h ough
an indi idual app oach o child en. To s udy he e ec i eness o d ug combina ions o educe side
e ec s o d ugs.To de elop new ea men p o ocols and ensu e e ec i e and sa e ea men h ough
clinical use.
Me hods and me hods: li e a u e analysis: an analysis o exis ing scien i ic li e a u e, clinical
esea ch and p ac ical expe imen s on educing d ug side e ec s in he ea men o
Oncogema ological diseases. S a is ical analysis: ma hema ical and s a is ical me hods a e used o
analyze esea ch esul s and ob ain s a is ically signi ican esul s.
Resul s: he expec ed esul s o he s udy include: Reducing side e ec s: wi h he help o he
selec ion o a ional d ugs, hei combina ion and gene ic indi idual app oaches, e en ewe side
e ec s a e obse ed in he ea men o oncogema ological diseases in child en. Imp o ing he
e ec i eness o ea men : by es ing new combina ions o d ugs, as well as indi idually adjus ing
he dosage and ea men cou ses, he e ec i eness o he ea men o oncogema ological diseases
inc eases. New p o ocols: new ea men p o ocols will be de eloped o educe he side e ec s o
medica ions, ensu ing sa e and mo e e ec i e ea men o child en. Pha macogene ic analysis: wi h
he help o pha macogene ic analysis, esul s a e ob ained in he s udy o he indi idual e ec s o
d ugs, as well as in he op imiza ion o gene ically based he apies.Imp o ed quali y o li e: as a esul
o educed side e ec s and e ec i e ea men , he o e all quali y o li e in child en is signi ican ly
imp o ed..
Conclusions: de eloping e ec i e s a egies o educe d ug side e ec s in he ea men o
Oncogema ological diseases, p o ides sa e and e ec i e ea men op ions o pa ien s. The
app oaches de eloped in his s udy inc ease ea men e ec i eness by p o iding an indi idual
app oach o d ug selec ion, especially o child en, op imizing ea men p o ocols, and applying
gene ic analysis. The esul s o he s udy will help o c ea e sa e and mo e e ec i e me hods o
202
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE “MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
dealing wi h oncogema ological diseases. These lead o a educ ion in he side e ec s o d ugs,
especially o child en, and an imp o emen in he quali y o li e.
