264
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE “MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
ANALYSIS OF THE TRACE ELEMENT COMPOSITION OF TOOTHPASTES
Radin M.A.
Radin M.M.1
Ba masho S.N.,
S . Pe e sbu g S a e Uni e si y o Chemis y and Pha macy, Depa men o Physical and
Ino ganic Chemis y, Russia
S . Pe e sbu g Pa lo S a e Medical Uni e si y, Depa men o P opaedeu ics o Den al
Diseases, Russia
e-mail: [email p o ec ed]
h ps://doi.o g/10.5281/zenodo.17334077
The aim o he s udy is o de e mine he mic o- and mac onu ien composi ion o oo hpas es
om a ious p ice ca ego ies using a omic emission spec al analysis o assess hei sa e y and
e ec i eness.
A omic emission spec al analysis is a me hod based on he s udy o he op ical emission spec a
o a oms ha occu du ing he ansi ion o elec ons om exci ed ene gy le els o he main ones.
Du ing he analysis, he sample is a omized in a high- empe a u e plasma (4000 °C), a e which he
cha ac e is ic spec al lines o he elemen s a e eco ded. The me hod allows o quali a i e and
quan i a i e analysis o he elemen al composi ion wi h high sensi i i y and selec i i y.
Ma e ials and me hods. The s udy was ca ied ou on a DFS-452 spec og aph wi h a
pho odiode eco ding sys em. Pas e samples we e applied o ca bon elec odes, exci ed in an a c
discha ge (18 A, 380 V), and hen analyzed in he ange o 190-1100 nm. The spec a we e p ocessed
using he A om so wa e and a da abase o spec al lines.
Resul s
1. Too hpas e o high p ice ca ego y (Fig. 1)
- Mac onu ien s: Na, P, Si, Zn, C , Fe, Mn.
- T ace elemen s: Cu, Ni, Ti, Al, V.
- The absence o oxic elemen s (Pb, As,
Hg)
con i ms compliance wi h s anda ds.
2. Low p ice oo hpas e:
- Mac onu ien s: Al, Ca, Na, Si, Zn.
- T ace elemen s: Cu, Fe, Mn, Ni, P, Ti, V.
The inc eased con en o Al (in he o m o
aluminum oxide) equi es an addi ional assessmen o he isks o accumula ion in he body.
Use ul elemen s we e ound in he s udied samples: Ca, P, Zn, hey con ibu e o he
emine aliza ion o enamel and ha e an ibac e ial p ope ies, Si (SiO2) is a sa e, al e na i e ab asi e.
Elemen s con ibu ing o po en ial isks: Al (Al2O3) is an al e na i e, mo e ha m ul ab asi e, can
bind phospha es, dis up ing mine al me abolism, C and Mn a e oxic in high concen a ions.
The me hod con i med he absence o oxic elemen s in he s udied pas es, bu e ealed
di e ences in he con en o unc ional componen s. Expensi e pas a shows a mo e balanced
composi ion wi h a p edominance o emine alizing and an imic obial elemen s. The da a ob ained
can be used o op imize oo hpas es o mula ions, aking in o accoun egional peculia i ies ( o
example, mine al de iciency in he so wa e o he No hwes ).
