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The Crete Declaration: Uniting Science for One Health

Author: Arvanitidis, Christos; Ameixa, Olga; Basset, Alberto; Chatzinikolaou, Eva; Coman, Claudia; Companys, Berta; De Leo, Francesco; Deneudt, Klaas; Drago, Federico; Eriksson, John; Ferrari, Tiziana; Georgiev, Teodor; Giuliano, Giovanni; Gruber, Stefan; Haberm
Publisher: Zenodo
DOI: 10.3897/rio.11.e176120
Source: https://zenodo.org/records/17540529/files/RIO_article_176120.pdf
Resea ch Ideas and Ou comes 11: e176120
doi: 10.3897/ io.11.e176120
Policy B ie
The C e e Decla a ion: Uni ing Science o One
Heal h
Ch is os A ani idis , Olga Ameixa , Albe o Basse , E a Cha zinikolaou , Claudia Coman , Be a
Companys , F ancesco De Leo , Klaas Deneud , Fede ico D ago , John E iksson , Tiziana Fe a i ,
Teodo Geo gie , Gio anni Giuliano , S e an G ube , Jens K Habe mann , Ka ha ina F Heil , Tim
Hubba d , C is ina Hue as Oli a es , Geo gios Ko oulas , Dimi is Kou eas , Na alia Manola ,
Vanessa Ma occo , Nicolas Pade , Ana Po ugal Melo , An onello P o enzale , Fo is E
Psomopoulos , Niels Raes , Susie Robinson , Pa ick Ruch , Dick Schaap , Ad ian S anica ,
Tassos S a opoulos , Heliana Teixei a , Pe e an Tiende en , Cos as Tsigenopoulos , Robe M
Wa e house , Giuseppe Ap ea , Michel Boë , Ana Casino , Lau en Delauney , Jona han Ewbank
Michael Mi l , Jana Pa lic-Zupanc , Lyubomi Pene , Jaume Pie a , Pa aske i Pi a ,
Ing id Puilla , Da id Rich e , Diana S epanyan , An on Ussi ,
Jan Ma cin Węsławski , Gab iela Zuquim
‡ Li eWa ch ERIC, Se ille, Spain
§ Uni e si y o A ei o (Res o e4C), A ei o, Po ugal
| Uni e si y o Salen o, Li eWa ch ERIC (SC), Lecce, I aly
¶ Na ional Reseach Council, Lecce, I aly
# Li eWa ch ERIC, Lecce, I aly
¤ IMBBC, HCMR (Li eWa ch ERIC), He aklion, C e e, G eece
« MARIS B.V., Noo do p, Ne he lands
» ICM, CSIC (P ojec ANERIS), Ba celona, Spain
˄ IRET, CNR (P ojec OEMC), Lecce, I aly
˅ Flande s Ma ine Ins i u e (VLIZ) (P ojec DTO BioFlow), Os end, Belgium
¦ EGI Founda ion (P ojec ENVRI Hub NEXT), Ams e dam, Ne he lands
ˀ Eu oBioImaging ERIC, Tu ku, Finland
ˁ EGI Founda ion, Ams e dam, Ne he lands
₵ Penso Publishe s, So ia, Bulga ia
ℓ ENEA (P ojec PRO-GRACE), Rome, I aly
₰ SHARE-ERIC, Be lin, Ge many
₱ BBMRI-ERIC, G az, Aus ia
₳ ELIXIR, Hinx on, Uni ed Kingdom
₴ Li eWa ch ERIC (SSO), Se ille, Spain
₣ IMBBC, HCMR, He aklion, C e e, G eece
₮ Na u alis Biodi e si y Cen e , DiSSCo RI (P ojec BGE), Leiden, Ne he lands
₦ OpenAIRE (P ojec OST ails), A hens, G eece
₭ Li eWa ch ERIC (SC), Lecce, I aly
₲ EMBRC-ERIC, Pa is, F ance
‽ MIRRI-ERIC, B aga, Po ugal
₩ IGG, CNR (P ojec ITINERIS), Pisa, I aly
₸ CERTH (P ojec EVERSE), Thessaloniki, G eece
‡‡ Na u alis Biodi e si y Cen e , Leiden, Ne he lands
§§ Na u alis Biodi e si y Cen e (P ojec BMD), Leiden, Ne he lands
|| EMPHASIS RI, Ghen , Belgium
¶¶ HES-SO - HEG Gene a, Gene a, Swi ze land
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© A ani idis C e al. This is an open access a icle dis ibu ed unde he e ms o he C ea i e Commons A ibu ion License (CC
BY 4.0), which pe mi s un es ic ed use, dis ibu ion, and ep oduc ion in any medium, p o ided he o iginal au ho and sou ce
a e c edi ed.
Re iewable 1
## MARIS B.V. (P ojec Blue Cloud), Noo do p, Ne he lands
¤¤ GeoEcoMa , DANUBIUS RI, Bucha es , Romania
«« CESAM & Uni e si y o A ei o (P ojec GES4SEAS), A ei o, Po ugal
»» Uni e si y o Ams e dam, Li eWa ch ERIC (VLIC), Ams e dam, Ne he lands
˄˄ IMBBC, HCMR, He aklion, G eece
˅˅ SIB Swiss Ins i u e o Bioin o ma ics (P ojec BGE), Lausanne, Swi ze land
¦¦ AnaEE-ERIC, Pa is, F ance
ˀˀ CETAF, B ussels, Belgium
ˁˁ IFREMER, JERICO RI, Plouzané, F ance
₵₵ ERINHA-AISBL, Pa is, F ance
ℓℓ UFZ, eLTER RI, Leipzig, Ge many
₰₰ Penso Publishe s & Bulga ian Academy o Sciences, So ia, Bulga ia
₱₱ IO, HCMR, AQUACOSM-plus, MESOAQUA, He aklion, C e e, G eece
₳₳ EMSO ERIC, Rome, I aly
₴₴ EATRIS-ERIC, Ams e dam, Ne he lands
₣₣ IOPAN (P ojec MARBEFES), Sopo , Poland
₮₮ CSC - IT Cen e o Science (P ojec BioDT), Espoo, Finland
Co esponding au ho : Ch is os A ani idis (ceo@li ewa ch.eu)
Recei ed: 26 Oc 2025 | Published: 04 No 2025
Ci a ion: A ani idis C, Ameixa O, Basse A, Cha zinikolaou E, Coman C, Companys B, De Leo F, Deneud K,
D ago F, E iksson J, Fe a i T, Geo gie T, Giuliano G, G ube S, Habe mann J, Heil K, Hubba d T, Hue as
Oli a es C, Ko oulas G, Kou eas D, Manola N, Ma occo V, Pade N, Po ugal Melo A, P o enzale A,
Psomopoulos F, Raes N, Robinson S, Ruch P, Schaap D, S anica A, S a opoulos T, Teixei a H, an Tiende en
P, Tsigenopoulos C, Wa e house R, Ap ea G, Boë M, Casino A, Delauney L, Ewbank J, Mi l M, Pa lic-Zupanc
J, Pene L, Pie a J, Pi a P, Puilla I, Rich e D, S epanyan D, Ussi A, Węsławski J, Zuquim G (2025) The
C e e Decla a ion: Uni ing Science o One Heal h. Resea ch Ideas and Ou comes 11: e176120.
h ps://doi.o g/10.3897/ io.11.e176120
Abs ac
The in e dependence o human, animal, plan and ecosys em heal h necessi a es
sys emic, c oss-domain collabo a ion o add ess global challenges, such as eme ging
diseases, clima e change and biodi e si y se e e change. Th ough he C e e
Decla a ion, Eu ope’s (e-)in as uc u es, o ganisa ions and p ojec s ha ocus on he
unc ioning o ou biosphe e commi o join ly ad ancing he One Heal h app oach. In
doing so, he signa o ies aim o s eng hen Eu ope’s esilience and leade ship h ough
he sha ing o da a and expe ise, he de elopmen o inno a i e solu ions and he
p omo ion o e idence-based policies.
Keywo ds
One Heal h, sys emic app oach, Resea ch (e-)In as uc u es, o ganisa ions and
collabo a i e p ojec s, open inno a ion, policy suppo
2A ani idis C e al
P eamble
We, he unde signed, ep esen ing Eu ope’s la ge-scale Resea ch (e-)In as uc u es,
o ganisa ions and collabo a i e p ojec s dedica ed o unde s anding he li ing
componen o Biosphe e, commi o joining o ces o ad ance he One Heal h app oach,
ecognising he in ima e and insepa able link be ween he heal h o people, animals and
plan s and how hey in e ac wi hin ecosys ems.
The wo ld aces u gen , in e connec ed challenges — eme ging diseases, epidemics and
an imic obial esis ance; ood sa e y and sus ainable p oduc ion; wa e sca ci y,
en i onmen al con amina ion and se e e change in biodi e si y — all in ensi ied by he
widesp ead impac o clima e change. These global h ea s demand a undamen al shi
owa ds sys emic, in eg a ed solu ions. Se e al majo EU ini ia i es al eady add ess pa s
o hese challenges, including he pa ne ships o pandemic p epa edness (Be Ready
Now), animal heal h and wel a e (EUPAHW) and One Heal h An imic obial Resis ance
(EUP OHAMR).
One Heal h calls o a “whole o socie y” app oach o heal h haza ds and a sys emic
change o pe spec i e in he managemen o isks wi h a long- e m s a egic ision o
ac ion. Resea ch In as uc u es in Eu ope a e in a pi o al posi ion o p o ide solu ions
ha a e i mly g ounded in obus science and e idence-based insigh s in o he
unc ioning o ou li ing en i onmen . Th ough collabo a ion and co-c ea ion wi h use s
and s akeholde s, esea ch ac o s p o ide uni ied da a and se ice in eg a ion and i mly
commi o open science as a d i e o scien i ic and social inno a ion.
Ou Sha ed Ambi ion
• P omo e mul idisciplina y and c oss-domain esea ch o add ess he mos u gen
One Heal h challenges;
• Uni e ou complemen a y s eng hs o p o ide in o ma ion o EU and na ional
policies wi h obus scien i ic e idence, embedding p epa edness by design
scien i ic knowledge in o policies and p ac ice;
• Suppo and ad ance open inno a ion h ough sha ed esou ces ha enable
echnological and socie al esponses o human-induced and na u al s esso s,
hus s eng hening Eu ope's esilience and global leade ship;
• Accele a e he up ake o eme ging me hods, including obse a ional,
expe imen al and compu a ional echnologies, wi h a special ocus on he
esponsible use o a i icial in elligence in One Heal h applica ions.
The C e e Decla a ion: Uni ing Science o One Heal h 3
Ou Commi men
We he eby commi o:
1. S eng hen S a egic Collabo a ion. In es in s uc u ed and sus ained
collabo a ion on One Heal h challenges and join ly engage wi h s akeholde s and
na ional and Eu opean unding agencies o p io i ise ac ions and wo k on he
ealisa ion o common goals;
2. Ad ance Da a In eg a ion and FAIR P inciples o Open Science. Ensu e
equi able access o ele an da a esou ces, so wa e, wo k lows, s anda ds and
p o ocols ac oss domains (bo h echnological and socio-economic);
3. Suppo Open Inno a ion. Es ablish us ed, inclusi e pla o m o s akeholde
engagemen , accele a ing inno a ion ac oss public and p i a e sec o s in c i ical
a eas such as species and ecosys ems conse a ion, sus ainable ood sys ems,
an imic obial esis ance and wa e secu i y;
4. In o m Policy and Public. P o ide in eg a ed scien i ic knowledge o p o ide
in o ma ion o e ec i e, e idence-based policy-making and engage ci izens.
Policies ancho ed in eliable da a a e obus and, when oo ed in socie al
pa icipa ion, hey will become mo e easible, impac ul and widely adop ed.
Nex S eps
This Decla a ion was de eloped du ing a special assembly held in C e e in June 2025,
hos ed by he Ins i u e o Ma ine Biology, Bio echnology and Aquacul u e, Hellenic
Cen e o Ma ine Resea ch. We in i e all Eu opean s akeholde s commi ed o One
Heal h, including policy-make s, Science Clus e s and he p i a e sec o , o endo se his
Decla a ion and join e o s owa ds a ede a ed and coo dina ed app oach o One Heal h
esea ch and inno a ion in Eu ope.
Con lic s o in e es
The au ho s ha e decla ed ha no compe ing in e es s exis .
Disclaime : This a icle is (co-)au ho ed by any o he Edi o s-in-Chie , Managing Edi o s
o hei depu ies in his jou nal.
4A ani idis C e al