Le e aging p o iling o b idge
heal hca e silos o ede a ed
analyses
Nelly Ba e , Anna Be nasconi, Cinzia Cappiello, Giacomo Palu, and Pie o Pinoli
Poli ecnico di Milano
June 27 h, 2025
Con ex : Fede a ed Lea ning o heal hca e
27/06/2025 P o iling heal hca e silos - Nelly Ba e e al.
Which genes
a o in elligence
disabili y in
child en?
How do gene ic and
clinical da a co ela e
in eye dys ophies?
2/18
Con ex : Fede a ed Lea ning o heal hca e
27/06/2025 P o iling heal hca e silos - Nelly Ba e e al.
Which genes
a o in elligence
disabili y in
child en?
How do gene ic and
clinical da a co ela e
in eye dys ophies?
I-ETL [1]
[1] N. Ba e e al. I-ETL: an in e ope abili y-awa e heal h (me a)da a
pipeline o enable ede a ed analyses. Unde e iew.
3/18
Con ex : Fede a ed Lea ning o heal hca e
27/06/2025 P o iling heal hca e silos - Nelly Ba e e al.
Which genes
a o in elligence
disabili y in
child en?
How do gene ic and
clinical da a co ela e
in eye dys ophies?
I-ETL [1]
[1] N. Ba e e al. I-ETL: an in e ope abili y-awa e heal h (me a)da a
pipeline o enable ede a ed analyses. Unde e iew.
[2] O. Beyan, e al. Dis ibu ed analy ics on sensi i e medical da a:
he pe sonal heal h ain. Da a In elligence. 2020 Jan 1;2(1-2):96-107.
PHT [2]
4/18
Modeling and p o iling heal hca e silos
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Modeling and p o iling heal hca e silos
27/06/2025 P o iling heal hca e silos - Nelly Ba e e al.
FAIRi ica ion
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FAIRi ica ion in a nu shell
Fo a gi en hospi al:
27/06/2025 P o iling heal hca e silos - Nelly Ba e e al.
Da a
Any pa ien da a ( eal o syn he ic)
Me ada a
Any in o ma ion p o iding
con ex /seman ic on he da a
I-ETL
Ex ac
T ans o m
Load
FAIR
da abase
7/18
Ou FAIR da a model
Modeling and p o iling heal hca e silos
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P oblem s a emen
How o help use s disco e homogenized silos
o design FL algo i hms?
We aim a a ca alogue which:
•Gene al and adap i e
•Disco e da a and me ada a
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Building he global ca alogue
Combine indi idual ca alogues o each silo:
•Union o all he indi idual ca alogues (one pe hospi al)
•Easy hanks o ou gene al ca alogue model
•Allows o implemen isualisa ions o all cen e s a a ime
When hospi als upda e hei da a:
•Recompu e he unde lying ca alogue
•Replace he old wi h he new indi idual ca alogue
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Lessons lea n and ou ision
•Exis ing wo ks: lack o gene ali y, app oach pe use-case
•FL equi es highly homogenized in as uc u es
•Balance gene aliza ion s. domain knowledge
•Da a and me ada a a e bo h necessa y
Abs ac ing cu en concep ual models is p omising:
→ Reuse, use case-agnos ic pipelines, a ious se ings
→ Easy explo a ion o la ge and complex silos
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Thank you!
27/06/2025 P o iling heal hca e silos - Nelly Ba e e al.
h ps://www.be e -heal h-p ojec .eu/
Nex s eps: silo empla e que ies, LLM-assis ed que ies, …
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