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Distances of transmission risk of Covid-19 inside dwellings and evaluation of the effectiveness of reciprocal proximity warning sounds

Abstract

One of the main modes of transmission and propagation of COVID-19 (SARS-CoV-2) is the direct contact with respiratory droplets transmitted among individuals at a certain distance. There are indoor spaces, such as dwellings, in which the transmission risk is high. This research aims to record and analyze risk close contacts in this scope, experimentally assessing the effectiveness of using electronic proximity warning sound devices or systems. For this purpose, the methodology is based on monitoring the location of the occupants of a dwelling. Then, the days in which a proximity warning sound system is installed and activated are compared to the days in which the system is not activated. The results stressed the significant reduction of time and number of close contacts among individuals when the warning was activated. Regarding the relation between the number and the duration of close contacts, together with the reductions mentioned, the possibility of making certain predictions based on the distributions obtained is proved. All this contributes to the progress in the prevention of COVID-19 transmission because of close contacts in dwellings.

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Distances of transmission risk of Covid-19 inside dwellings and evaluation of the effectiveness of reciprocal proximity warning sounds

Author: Marín García, David; Moyano, Juan; Bienvenido Huertas, José David
Publisher: John Wiley
Year: 2021
DOI: 10.1111/ina.12738
Source: https://idus.us.es/bitstreams/3590a235-7fd2-4e81-bede-371408b99971/download
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Ga cía D, Moyano-Campos JJ, Bien enido-Hue as JD. Dis ances o
ansmission isk o COVID-19 inside dwellings and e alua ion o he
e ec i eness o ecip ocal p oximi y wa ning sounds. Indoo Ai . 2021; 31: 335
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Dis ances o ansmission isk o Co id-19 inside dwellings and e alua ion
o he e ec i eness o ecip ocal p oximi y wa ning sounds
Da id Ma ín-Ga cía1*, Juan Moyano-Campos 1, Da id Bien enido-Hue as2
1Depa men o G aphical Exp ession and Building Enginee ing, Highe Technical School o
Building Enginee ing, Uni e si y de Se ille. 4A Reina Me cedes A enue, Se ille 41012, Spain
2Depa men o Building Cons uc ion II, Highe Technical School o Building Enginee ing,
Uni e si y de Se ille. 4A Reina Me cedes A enue, Se ille 41012, Spain
*Co esponding email: [email p o ec ed]
ABSTRACT
One o he main modes o ansmission and p opaga ion o Co id-19 (SARS-CoV-2) is he di ec
con ac wi h espi a o y d ople s ansmi ed among indi iduals a a ce ain dis ance. The e a e
indoo spaces, such as dwellings, in which he ansmission isk is high. This esea ch aims o
eco d and analyse isk close con ac s in his scope, expe imen ally assessing he e ec i eness
o using elec onic p oximi y wa ning sound de ices o sys ems. Fo his pu pose, he
me hodology is based on moni o ing he loca ion o he occupan s o a dwelling. Then, he days
in which a p oximi y wa ning sound sys em is ins alled and ac i a ed a e compa ed o he days
in which he sys em is no ac i a ed. The esul s s essed he signi ican educ ion o ime and
numbe o close con ac s among indi iduals when he wa ning was ac i a ed. Rega ding he
ela ion be ween he numbe and he du a ion o close con ac s, oge he wi h he educ ions
men ioned, he possibili y o making ce ain p edic ions based on he dis ibu ions ob ained is
p o ed. All his con ibu es o he p og ess in he p e en ion o Co id- 19 ansmission because
o close con ac s in dwellings.
KEYWORDS:
Co id-19; dwellings; close con ac s; p oximi y wa ning.
PRACTICAL IMPLICATIONS
-Cu en ly, Co id-19 is a global epidemic ha causes hund eds o housands o dea hs and high
economic epe cussions a ound he wo ld. Despi e ad ances in diagnosis and ea men , he
global incidence emains high and addi ional s a egies o p e en ion a e u gen ly equi ed.
-This s udy p o ides he i s empi ical da a showing ha he applica ion o an elec onic
p oximi y wa ning sound sys em is e ec i e in imp o ing he con ol o a Co id-19 ou b eak
in indoo en i onmen o a dwelling, also being a b eak h ough in eco ding sys ems and
analysing he isk o close con ac s in dwellings and in he possibili y o p edic o he numbe
o such con ac s.
1. INTRODUCTION
Ce ain beha iou s and cha ac e is ics o indi iduals a e di ec ly ela ed o he le el o in ec ion
isk 1 3, and close con ac s a e he main causes o he expansion o many i al espi a o y
diseases 4 9. These close con ac s usually en ails a ce ain in e pe sonal dis ance which
acili a es he inhala ion o i al d ople s 10,11. B ea hing, alking, coughing, and sneezing a e
ac i i ies ha p oduce such d ople s in a ious amoun and size 12 16. The dis ance ha hese
d ople s can each, and he e o e he secu i y dis ance among indi iduals, has been epea edly
s udied o se e al ypes o si ua ions 17 19.
Since 31 Decembe 2019, when he Wuhan Municipal Heal h Commission (Wuhan is in he
p o ince o Hubei, China) communica ed o he Wo ld Heal h O ganisa ion (WHO) he
exis ence o pa ien s a ec ed by Co id-19, he wo ld scien i ic communi y knows much be e
his i us, pa icula ly i s in ec ious beha iou . Simila ly o o he co ona i us, he main mode
o ansmission, al hough no he only one 20 22, is he con ac wi h espi a o y d ople s, ha is,
he mucus o he mou h, nose o eyes 23, as he i us is ound in nasopha yngeal sec e ions and
sali a 24. Thus, he modes o ansmission and p opaga ion among indi iduals, i indi iduals do
no use o he means o p o ec ions, a e di ec ly ela ed o he dis ance among hem and he
exposu e ime. A close in e pe sonal dis ance implies a g ea e inhala ion o he i us, hus
inc easing he isk o in ec ion h ough he close con ac ou e 25. A e analysing he exis ing
esea ch s udies ying o es ablish he mos adequa e secu i y dis ance, i is clea ly deduced
ha he e is no unanimi y when es ablishing an accu a e unique dis ance 26 because many
ac o s could a y he dis ance om a me e o eigh o nine me es o speci ic si ua ions, such
as sneezes 27,28. Howe e , a ious bodies and coun ies ha e ecommended o keep minimum
dis ances among indi iduals be ween one 29 and wo me es 30 because his is gene ally a
easonable measu e o educe he isk o in ec ion as long as he e a e no o he ac o s
con ibu ing o p opaga ion, such as s ong sneezes, ai cu en s, in ec ious ae osols in closed
spaces 31 o con ac s wi h con amina ed su aces 32.
Recen esea ch s udies 33 and expe s like B omage 34 indica ed ha mos ansmissions a e he
esul o he sp ead o he in ec ion a home. I a amily membe is in ec ed ou side he dwelling,
hen he o he membe s usually become in ec ed when he in ec ed indi idual e u ns. This ac
is con i med by Qian e al. 33, who iden i ied 318 ou b eaks wi h 3 o mo e cases, in ol ing
1,245 cases con i med in 120 ci ies.
The scien i ic li e a u e ela ed o ansmissions in buildings 35, he sp ead o in ec ion in amily
en i onmen s and households 36 and he beha iou o close con ac s including he body
posi ioning in de ail 37 is almos unanimous in conside ing ha in a closed a chi ec u al
en i onmen , such as dwellings and simila spaces, he isk o ansmission due o p oximi y is
high, pa icula ly i an occupan is in ec ed ou side and li es wi h he o he occupan s o he
dwelling. The main easons a e he cha ac e is ics o hese closed spaces and he
beha iou because he e is usually a g ea e in e ac ion among hem 38, pa icula ly in modes
dwellings and in si ua ions in which he cohabi a ion is in ensi ied 36. In hese cases, he
ansmission isk is closely ela ed o he dis ance and posi ion among indi iduals, he numbe s
o indi iduals, he ac ions ela ed o he expulsion o con amina ed d ople s (sneezing,
coughing, speaking o jus b ea hing), and he exposu e ime, among o he speci ic
cha ac e is ics o hese spaces. Ne e heless, he le el o p esence o he i us due o he
exposu e ime is he acking basis o he isk close con ac . Al hough sneezing o coughing
implies su icien i al d ople s o di ec ly in ec , some minu es alking ace- o- ace o an
in ec ed people 10,39 and e en 20 minu es exposed o hei b ea hing a e necessa y o be in ec ed,
all his based on he numbe o d ople s expelled and ecei ed pe minu e 34.
Va ious companies and en ep eneu s om he echnological sec o a e oday o e ing wa ning
sound de ices and sys ems which, wi h g ea e o lowe success, in end o de ec he ecip ocal
p oximi y among indi iduals. These de ices o sys ems a e applying se e al echnologies and
p ocedu es and a e p esen ed in a ious o ma s, such as independen uni s, applica ions o
sma phones, e c. This esea ch is he e o e ocused on analysing he e ec i eness o hese
de ices by applying hem in a dwelling whose dimensions, cha ac e is ics, and amily uni a e
ela i ely common. Fo his pu pose, his esea ch is based on he s udies on he human
beha iou when he e a e non- e bal wa ning sounds 40,41. In addi ion, an expe imen al
campaign is conduc ed in a eal en i onmen by using spa ial posi ion loca o s, and a sys em
ha gene a es a wa ning sound i ecip ocal p oximi y is de ec ed among indi iduals is
es ablished. I should be emphasized ha i he e is no in ec ed indi idual in he dwelling, hen
amily membe s can be close. Fo his eason, his esea ch ocuses bo h on he hypo hesis ha
he isk exis s when a amily membe mee s o he indi iduals, becomes in ec ed and e u ns
home and on he analysis o o wha ex en hese de ices o sys ems a e e ec i e o con ol and
p e en in ec ions ela ed o social dis ance, such as he case o Co id-19.
2. SIMILAR WORKS

Se e al esea ch s udies ha e eco ded he eal- ime loca ion o indi iduals and ha e analysed
he du a ion and dis ance o con ac s in a ce ain pe iod and in a ious indoo spaces 2,37,42 46;
howe e , no esea ch analyses and compa es he esul s om ac i a ing o no a wa ning sound
de ice o sys em o a oid close con ac and he e o e ansmission in a dwelling like ha
chosen.
3. MATERIALS AND METHODS
As a es bed, a dwelling loca ed in he sou h o Spain was used. I s cha ac e is ics and he
amily uni li ing in i a e usual in his coun y 47.
3.1. Cha ac e is ics o he dwelling and amily uni
The dwelling has a hall, a li ing-dining oom, a ki chen, h ee bed ooms, wo ba h ooms, a
balcony, and a co ido , all made independen by walls and doo s. The occupan s o he amily
uni a e ou indi iduals (a man, a woman, a boy, and a gi l). The adul s a e be ween 40 and 50
yea s old, and he subjec s unde 18 a e 10 and 12 yea s old. All occupan s ha e been li ing in
he dwelling o mo e han en yea s, so hey a e amilia ized wi h he expe imen al
en i onmen , hus compensa ing any bias o igina ed by ha en i onmen . The ac ual spa ial
cha ac e is ics, dimensions, uses, su aces, and u ni u e o he dwelling a e eliably ep esen ed
wi h he lowes possible e o by using a h ee-dimensional modelling Au odesk Re i 2019®
48. The model and ep esen a ion o he loo s co esponding o he dwelling (Fig. 1) a e used
in he g aph o he loca ion da a ob ained.
3.2. De ec ion de ices
Fo he expe imen al phase, de ec ion de ices we e used o he eal- ime loca ion o each
subjec . Gi en ha hese de ices should p o ide eadings as accu a e as possible ega ding he
eco ding o he loca ion om which he in e pe sonal dis ance could be deduced, he
echnologies no mee ing hese equi emen s we e no conside ed, ollowing he speci ici ies o
he scien i ic li e a u e 42,49,50. As a esul , he eal- ime loca ing sys em (RTLS) based on ul a-
wide band (UWB) was he mos adequa e echnology o he pu pose o his esea ch 49,51
55. Based on bo h he compa isons conduc ed by o he au ho s 56 and ou analysis and a ailable
esou ces, a Decawa e® 57 equipmen was chosen as he e we e expe imen al p eceden s in
se e al spaces and si ua ions 58 65. This equipmen is an ul a-wideband ne wo k cons i u ed by
ixed nodes (ancho s) and mo ing nodes ( ags). Rega ding he accu acy, al hough
±10 cen ime es and second in e als, o he
indica ions we e also conside ed 66,67. Howe e , hese echnical cha ac e is ics we e adap ed o
he basic equi emen s o his ype o expe imen a ion in ela ion o he eal- ime collec ion o
mode which each expe imen al subjec pe manen ly had, and he emaining ancho s we e
placed in he walls o he dwelling nea o he ceiling. The sys em gene a ed eal- ime da a
which we e collec ed by a mobile de ice and a compu e hough he p ocedu e, he so wa e
and he APIs indica ed by he manu ac u e . On he o he hand, an Excel® sp eadshee was
used o he da a compila ion and p ocessing, and Mic oso Visual S udio®68 o he
p og amming o some algo i hms, as well as H ml, Php, and Mysql, among o he s. When an
indi idual was ge ing close o ano he o o he s om a ce ain dis ance, a no e y high sound
signal, bu audible, was gene a ed, whose one and in ensi y we e p e iously chosen by he
expe imen al subjec s o be as mos pleasan as possible. To sum up, he sys em was designed
by placing ancho s in se e al poin s o he dwelling and ags o he expe imen al subjec s (Fig.
2), so he loca ion da a o hese subjec s we e gene a ed. A e da a p ocessing, he dis ances
among subjec s we e de e mined, and all was coo dina ed by po able Blue oo h Speake s o
he p oximi y wa ning sound sys em among indi iduals. The placing o he ancho s he e o e
cons i u ed a coo dina e sys em o an o igin co esponding o one o hese ancho s, so he
dis ance om each ag o each ancho was calcula ed, hus allowing he ags o be always placed
as he ini ial coo dina es o he ancho s we e known because hey we e p e iously de e mined.
Las ly, be o e s a ing he expe imen a ion, he co ec calib a ion o de ices was checked by
e i ying i he o e ed da a co esponded o ac ual da a.
3.3. Dis ance and isk posi ion conside ed
This s udy only conside ed he dis ances among expe imen al subjec s and no hei co po al
posi ion due o he easons men ioned below.
To make he goal o he esea ch easible ega ding he compa a i e s udy, he concep o isk
con ac o was ini ially es ablished in a unique, clea and accu a e way.
Conside ing he au ho s a o emen ioned and he indica ions gi en by he mos known
in e na ional heal h o ganisa ions, such as WHO 29 o he Eu opean Cen e o Disease
P e en ion and Con ol (ECDC) 30, he app oaches a a dis ance less han 2 me es o
a household as long as he con ac ook place wi hou
p o ec ion ( ace mask, eye p o ec ion, e c.). Rega ding ime, al hough he du a ion o 15 minu es
is used in ce ain scopes 30, he secu i y ma gin was inc eased by using 10 minu es. The same
occu ed when 2 me es we e chosen, ins ead o 1 me e, as ecommended in some cases.
As o he exposu e ime, he e is no absolu e ce ain y o how many pa icles should be inhaled
and he e o e how much exposu e ime is necessa y in each ci cums ance o p oduce a
ansmission. Fo his eason, his s udy uses a ime ma k ha may seem high bu assu es ha
he esul s e lec high- isk con ac s.
A e coun ing close con ac s, al hough hey we e i s de ined as episodes o 10 con inuous
minu es a less han 2 me es in some momen s, some cases we e no s ic ly sui able o hese
condi ions. Howe e , hese cases we e also conside ed because one o hese condi ions was
ul illed and he o he was almos ul illed.
The goal o he esea ch was no o es ablish whe he ansmissions would ake place a o he
dis ances o exposu e imes di e en o hose p e iously chosen. The main goal was o assess
he e ec i eness o p oximi y wa ning sound de ices o sys ems wi h espec o
beha iou when a oiding dis ances which could imply his ansmission, ega dless o whe he
he ansmission was p oduced, so he easonable and ounded e e ences chosen we e enough.
3.4. Da a collec ion and p ocessing
Rega ding he da a collec ion, all occupan s we e moni o ed om he hou in which he i s
occupan go up in he mo ning o he hou in which he las occupan wen o bed a nigh , so
he p og ammed ime was om 8:00 a.m. o 24:00 p.m. (16 hou s). When a subjec go up, he
loca ion de ice was immedia ely placed and ac i a ed. Howe e , he connec ion o he wa ning
sound de ice was no ac i a ed un il a leas 2 subjec s go up, a ound 9:00 a.m. On he o he
hand, he subjec s on bed a e 8:00 a.m. we e assigned a ixed coo dina e o hei loca ions
which coincided wi h he lying posi ion in hei espec i e bed un il hey also go up and he
loca ion de ise was placed and ac i a ed. The expe imen al days coincided wi h he
con inemen days dec eed by he Spanish Go e nmen in Ma ch 2020, so all amily membe s
s ayed in he dwelling all he expe imen al hou s. The in e nal empe a u e was be ween 21 and
23 ºC. Acco ding o he Spanish Building Technical Code, he en ila ion a e o dwellings was
0.94 ai changes pe hou . In hese expe imen al days, he dis ances o he ags o each subjec
o he ancho s we e ob ained a each momen . Wi h hese da a and by iangula ion, he
coo dina es (x, y) o each indi idual we e au oma ically ob ained in eal ime, and he
coo dina e (z) was no equi ed, as p e iously jus i ied, conside ing he goal. No all he
coo dina es we e he esul o he da a eco d p o ided by he loca ion de ices because hese
we e upda ed based on he ac i i y o he mo emen senso . In addi ion, ce ain dispa i ies we e
u n en ails he dis ibu ions and hei espec i e g aphs. This esea ch showed ha sho close
con ac s we e he mos usual, hus dec easing he equency as he du a ion inc eased by
ollowing a loga i hmic dis ibu ion.
The ansmission isk inc eased by educing he in e pe sonal dis ance, and ice e sa 18,69
71. Al hough he loca ion o indi iduals could no be accu a ely quan i ied a each momen ,
human beha iou usually a ied acco ding o ce ain ac o s al eady men ioned 2,3. Based on
he esul s, all subjec s esponded o he wa ning in a simila way mos o he ime. Gi en he
amily uni and he dwelling analysed, i would be in e es ing and e en in ce ain cases
necessa y o expe imen wi h se e al dwelling ypologies and amily uni s o di e si y he es
bed and o ob ain mo e da a o e i y he esul s, and e en o add conclusions.
Rega ding he esul s o he means o he dis ances in he day when he wa ning sound was no
ac i a ed, he mean pe sonal dis ances in case o mo e a ec i e subjec s we e he mos equen
and some imes e en ine i able, al hough he wa ning sound was connec ed. These isk con ac s
we e usual acco ding o wha some au ho s indica ed 25,37.
As o he ac i i ies and he way o ci cula ion o subjec s h oughou he day, al hough habi s
s ongly in luenced he p obabili y o close con ac s, he esul s also showed ha hese habi s
could be modi ied by he wa ning sound, hus g ea ly educing hese con ac s, a leas in he
sho e m. In his ega d, he subjec s, who a he same ime we e ca ying ou di e en
ac i i ies, usually eco ded a low p obabili y o con ac among hem, hus indica ing ha he
design o dwellings should in luence his aspec con ibu ing ha each subjec has hei own
space acco ding o he ac i i y. In his manne , subjec s could ca y ou hei ac i i ies in a
zones, pa icula ly i hey we e awa e o a possible close con ac , such as he case when he
wa ning sound was ac i a ed.

On he o he hand, he zones wi h com o able sea s we e usually ho spo s o con ibu e o close
con ac s, and i hese sea s we e big, such as he so a, and play ul ac i i ies could be ca ied
ou , hey u ned in o a space whe e con ac s we e equen e en wi h he wa ning sound
connec ed, as subjec s usually sa oge he .
Ano he aspec was a high p obabili y o sho close con ac s when he subjec s wen om a
poin o ano he o he house as he subjec s who coincided in he passing places o he dwelling
did no gene ally ha e enough space as hese zones we e no wide enough o keep he dis ance
equi ed. Ne e heless, con ac s we e sho and spo adic in hese cases. The pe o mance o he
senso s was gene ally adequa e; howe e , o ely on he mo ion senso s, hese we e checked a
in e als simila o he imes es ablished o conside close con ac s. Da a we e no gene ally
co ec ed, bu when he ags we e away om he ancho s o when he e we e mo e obs acles
be ween hem da a we e co ec ed.
Finally, hese esul s could be use ul o analyse he isk o in ec ion a a g ea e scale. Fo
ins ance, i he numbe o dwellings, hei ypology, and amily uni s in he households o a
ce ain zone a e known, he numbe o close con ac s which could be educed by applying
wa ning sound de ices o sys ems could be calcula ed.
6. CONCLUSIONS
The p obabili y o isky close con ac a a dis ance less han 2 me es is e y high in closed
spaces, such as dwellings, and he human beha iou inside hem is a de e minan ac o o he
ansmission isk.
Close con ac s could be dec eased wi h hese wa ning sound de ices o sys ems, making he
con ac s almos null.
Bo h when he wa ning de ice was disconnec ed and connec ed, he li ing- oom o he
dwelling, and pa icula ly he so a, he zones in which people usually ea , and he ki chen we e
he zones whe e close con ac s we e mo e equen and he e o e he e was a g ea e p obabili y
o p oximi ies a a dis ance less han 2 me es o mo e ime. In his ega d, he subjec s ca ying
ou di e en ac i i ies a he same ime usually eco ded a low p obabili y o con ac among
hem, hus indica ing ha he design o dwellings should acili a e ha each subjec has hei
own space o he espec i e ac i i ies. Howe e , he e was an impo an dec ease o close
con ac s in hese places when he wa ning sound was connec ed.
On he o he hand, i he wa ning was disconnec ed, he esul s indica ed ha he ela ion
be ween du a ion da a and he sum o con ac s ollowed loga i hmic dis ibu ions. I he wa ning
was connec ed, he dis ibu ion was linea a e a ound 5 minu es, o exponen ial including
hese 5 minu es, so p edic ions could be made wi h a de e mina ion coe icien g ea e han
80%. Based on he da a o some o hese wo a iables, he o he a iable could be deduced
wi h a p obabili y o success o 80%, al hough his limi should be inc eased by s udying a mo e
ex ensi e casuis y.
Rega ding a mo e long- e m easibili y o using wa ning sounds in a dwelling, and acco ding
o wha expe imen al subjec s mani es ed, i could be less easible i i is in ended o be used
o a long ime. On he o he hand, he e a e s ill si ua ions in which secu i y dis ances a e no
espec ed consciously, whe he he wa ning is connec ed o no , ei he because i is ma e ially
di icul o ul il acco ding o he cha ac e is ics o he dwelling o because he op ions o
al e na i es o he dis ance a e con a y o ce ain habi s which subjec s do no wan o
enounce ega ding hei ela ionships as amily uni . Finally, as he day passed, he wa ning
was less e ec i e.
Funds and con lic s o In e es : This esea ch has no been inanced. The au ho s decla e no
con lic s o in e es s.
Da a a ailabili y s a emen : Resea ch da a a e no sha ed.
REFERENCES
1. Heyda ian A, McIl ennie C, A pan L, e al. Wha d i es ou beha io s in buildings? A
e iew on occupan in e ac ions wi h building sys ems om he lens o beha io al
heo ies. Build En i on. 2020;179:106928. doi:10.1016/j.builden .2020.106928
2. Zhang N, Huang H, Su B, Ma X, Li Y. A human beha io in eg a ed hie a chical
model o ai bo ne disease ansmission in a la ge ci y. Build En i on. 2018;127:211-
220. doi:10.1016/j.builden .2017.11.011
3. Heshka S, Nelson Y. In e pe sonal Speaking Dis ance as a Func ion o Age, Sex, and
Rela ionship. Sociome y. 1972;35(4):491. doi:10.2307/2786529
4. Tu geon N, Hamelin M-È, Ve eaul D, e al. Design and Valida ion wi h In luenza A
Vi us o an Ae osol T ansmission Chambe o Fe e s. In J En i on Res Public
Heal h. 2019;16(4):609. doi:10.3390/ije ph16040609
5. Rea E, La lèche J, S alke S, e al. Du a ion and dis ance o exposu e a e impo an
p edic o s o ansmission among communi y con ac s o On a io SARS cases.
Epidemiol In ec . 2007;135(6):914-921. doi:10.1017/S0950268806007771
6. Lee KM, Jung K. Fac o s in luencing he esponse o in ec ious diseases: Focusing on
he case o sa s and me s in sou h ko ea. In J En i on Res Public Heal h. 2019;16(8).
doi:10.3390/ije ph16081432
7. De Wi E, Van Do emalen N, Falza ano D, Muns e VJ. SARS and MERS: Recen
insigh s in o eme ging co ona i uses. Na Re Mic obiol. 2016;14(8):523-534.
doi:10.1038/n mic o.2016.81
8. Webe DJ, Ru ala WA, Fische WA, Kanamo i H, Sickbe -Benne EE. Eme ging
in ec ious diseases: Focus on in ec ion con ol issues o no el co ona i uses (Se e e
Acu e Respi a o y Synd ome-CoV and Middle Eas Respi a o y Synd ome-CoV),
hemo hagic e e i uses (Lassa and Ebola), and highly pa hogenic a ian in luenza
i uses, A(H5N1) and A(H7N9). Am J In ec Con ol. 2016;44(5):e91-e100.
doi:10.1016/j.ajic.2015.11.018
9. Uma A, Sheshi M, Su iyan M, Abubaka A. Knowledge and p ac ice o Ebola i us
disease p e en i e measu es among heal h wo ke s in a e ia y hospi al in No he n
Nige ia. A ch Med Su g. 2018;3(1):1. doi:10.4103/a chms.a chms_45_17
10. Xie X, Li Y, Chwang ATY, Ho PL, Se o WH. How a d ople s can mo e in indoo
Indoo Ai .
2007;17(3):211-225. doi:10.1111/j.1600-0668.2007.00469.x
11. G al on J, To ey E, McLaws ML, Rawlinson WD. The ole o pa icle size in
ae osolised pa hogen ansmission: A e iew. J In ec . 2011;62(1):1-13.
doi:10.1016/j.jin .2010.11.010
12. Duguid JP. The size and he du a ion o ai -ca iage o espi a o y d ople s and d ople -
nuclei. Epidemiol In ec . 1946;44(6):471-479. doi:10.1017/S0022172400019288
13. Loudon R, Na u e RR-, 1967 unde ined. Rela ion be ween he Ai bo ne Diame e s o
Respi a o y D ople s and he Diame e o he S ains Le a e Reco e y.; 1967.
h ps://link.sp inge .com/con en /pd /10.1038/213095a0.pd . Accessed Ap il 13, 2020.
14. Chao CYH, Wan MP, Mo awska L, e al. Cha ac e iza ion o expi a ion ai je s and
d ople size dis ibu ions immedia ely a he mou h opening. J Ae osol Sci.
2009;40(2):122-133. doi:10.1016/j.jae osci.2008.10.003
15. Fabian P, McDe i JJ, DeHaan WH, e al. In luenza Vi us in Human Exhaled B ea h:
An Obse a ional S udy. Fouchie RAM, ed. PLoS One. 2008;3(7):e2691.
doi:10.1371/jou nal.pone.0002691
16. Xie X, Li Y, Sun H, Liu L. Exhaled d ople s due o alking and coughing.
oyalsocie ypublishing.o g. 2009;6(suppl_6). doi:10.1098/ si .2009.0388. ocus
17. Zhang N, Tang JW, Li Y. Human beha io du ing close con ac in a g adua e s uden
o ice. Indoo Ai . 2019;29(4):577-590. doi:10.1111/ina.12554
18. Liu L, Li Y, Nielsen P V., Wei J, Jensen RL. Sho - ange ai bo ne ansmission o
expi a o y d ople s be ween wo people. Indoo Ai . 2017;27(2):452-462.
doi:10.1111/ina.12314
19. Wei J, Li Y. Enhanced sp ead o expi a o y d ople s by u bulence in a cough je . Build
En i on. 2015;93(P2):86-96. doi:10.1016/j.builden .2015.06.018
20. WHO. Q&A on co ona i uses (COVID-19). Q&A on co ona i uses (COVID-19)
2020. h ps://www.who.in /news- oom/q-a-de ail/q-a-co ona i uses. Accessed Ap il
18, 2020.
21. CDC. How Co ona i us Sp eads | CDC. Co ona i us Disease 2019 (COVID-19) 2019.
h ps://www.cdc.go /co ona i us/2019-nco /p e en -ge ing-sick/how-co id-
sp eads.h ml?CDC_AA_ e Val=h ps%3A%2F%2Fwww.cdc.go %2Fco ona i us%2F
2019-nco %2Fp epa e%2F ansmission.h ml. Accessed Ap il 18, 2020.
22. Galbadage T, Pe e son BM, Gunaseke a RS. Does COVID-19 Sp ead h ough D ople s
Alone?; 2020. h ps://digi alcommons.biola.edu/ acul y-a icles/408. Accessed Ap il
18, 2020.
23. Hung LS. The SARS Epidemic in Hong Kong: Wha Lessons ha e we Lea ned? J R
Soc Med. 2003;96(8):374-378. doi:10.1177/014107680309600803
24. To KK-W, Tsang OT-Y, Yip CC-Y, e al. Consis en De ec ion o 2019 No el
Co ona i us in Sali a. Clin In ec Dis. 2020. doi:10.1093/cid/ciaa149
25. So okowska A, So okowski P, Hilpe P, e al. P e e ed In e pe sonal Dis ances: A

Global Compa ison. J C oss Cul Psychol. 2017;48(4):577-592.
doi:10.1177/0022022117698039
26. Se i L, Passa ini F, De Genna o G, e al. Ai bo ne T ansmission Rou e o COVID-19:
Why 2 Me e s/6 Fee o In e -Pe sonal Dis ance Could No Be Enough. In J En i on
Res Public Heal h. 2020;17(8):2932. doi:10.3390/ije ph17082932
27. Bou ouiba C, Dehandschoewe cke E, M Bush JW, Bou ouiba L. Violen Expi a o y
E en s: On Coughing and Sneezing. J Fluid Mech. 2014;745:537-563.
doi:10.1017/j m.2014.88
28. Bou ouiba L. A sneeze. N Engl J Med. 2016;375(8):e15.
doi:10.1056/NEJMicm1501197
29. Co ona i us. h ps://www.who.in /heal h- opics/co ona i us# ab= ab_2. Accessed May
29, 2020.
30. Case de ini ion and Eu opean su eillance o COVID-19, as o 2 Ma ch 2020.
h ps://www.ecdc.eu opa.eu/en/case-de ini ion-and-eu opean-su eillance-human-
in ec ion-no el-co ona i us-2019-nco . Accessed May 29, 2020.
31. Ci cle T, A lan a NE, Fishe S, e al. ASHRAE Posi ion Documen on. 2012.
h ps://www.ash ae.o g/ ile lib a y/abou /posi ion
documen s/pd_in ec iousae osols_2020.pd .
32. Zhang N, Li Y, ai HH-I, 2018 unde ined. Su ace ouch and i s ne wo k g ow h in a
g adua e s uden o ice. Wiley Online Lib .
h ps://onlinelib a y.wiley.com/doi/abs/10.1111/ina.12505. Accessed May 28, 2020.
33. Qian H, Miao T, LIU L, Zheng X, Luo D, Li Y. Indoo ansmission o SARS-CoV-2.
medRxi . 2020;(17202719):2020.04.04.20053058. doi:10.1101/2020.04.04.20053058
34. B omage E. The Risks - Know Them - A oid Them.
h ps://www.e inb omage.com/pos / he- isks-know- hem-a oid- hem. Published 2020.
Accessed May 20, 2020.
35. Die z L, Ho e PF, Coil DA, F e z M, Van Den Wymelenbe g K. 2019 No el
Co ona i us (COVID-19) Pandemic: Buil En i onmen Conside a ions To Reduce
T ansmission 97403-523. 2020. doi:10.20944/p ep in s202003.0197. 3
36. Qian G, Yang N, Ma AHY, e al. A COVID-19 T ansmission wi hin a amily clus e
by p esymp oma ic in ec o s in China. Clin In ec Dis. 2020:19-20.
doi:10.1093/cid/ciaa316
37. Zhang N, Su B, Chan PT, Miao T, Wang P, Li Y. In ec ion sp ead and high- esolu ion
de ec ion o close con ac beha io s. In J En i on Res Public Heal h. 2020;17(4).
doi:10.3390/ije ph17041445
38. A nold J, G aesch A, Ochs E, Ragazzini E. Li e a Home in he Twen y-Fi s Cen u y:
32 Families Open Thei Doo s. (ISD LLC, ed.).; 2012.
h ps://books.google.es/books?hl=es&l =&id= WmRDwAAQBAJ&oi= nd&pg=PP1&
dq=Li e+a +Home+in+ he+Twen y-
Fi s +Cen u y:+32+Families+Open+Thei +Doo s&o s= N P-
bjQN8&sig= 2 QWcxaJk 012DnBsTe1XDQxes. Accessed Ap il 18, 2020.
39. McFa land DH. Respi a o y Ma ke s o Con e sa ional In e ac ion. J Speech, Lang
Hea Res. 2001;44:128-143. doi:h ps://doi.o g/10.1044/1092-4388(2001/012)
40. Edwo hy J, Hellie E, Wal e s K, Weedon B, Adams A. The Rela ionship be ween
Task Pe o mance, Reac ion Time, and Pe cei ed U gency in Non e bal Audi o y
Wa nings. P oc Hum Fac o s E gon Soc Annu Mee . 2000;44(22):674-677.
doi:10.1177/154193120004402247
41. Edwo hy J, Loxley S, Dennis I. Imp o ing audi o y wa ning design: ela ionship
be ween wa ning sound pa ame e s and pe cei ed u gency. Hum Fac o s.
1991;33(2):205-231. doi:10.1177/001872089103300206
42. Vanhems P, Ba a A, Ca u o C, e al. Es ima ing Po en ial In ec ion T ansmission
Rou es in Hospi al Wa ds Using Wea able P oximi y Senso s. jou nals.plos.o g.
2013;8(9). doi:10.1371/jou nal.pone.0073970
43. Isella L,
c owd? Analysis o ace- o- ace beha io al ne wo ks. J Theo Biol. 2011;271(1):166-
180. doi:10.1016/j.j bi.2010.11.033
44. Sala hé M, Kazandjie a M, Lee JW, e al. A high- esolu ion human con ac ne wo k
o in ec ious disease ansmission. Na l Acad Sci. 2010;107(51):22020-22025.
doi:10.1073/pnas.1009094108
45. S ehlé J, Voi in N, Ba a A, e al. High- esolu ion measu emen s o ace- o- ace
con ac pa e ns in a p ima y school. PLoS One. 2011;6(8).
doi:10.1371/jou nal.pone.0023176
46. S ehlé J, Voi in N, Ba a A, e al. Simula ion o an SEIR in ec ious disease model on
he dynamic con ac ne wo k o con e ence a endees. BMC Med. 2011;9.
doi:10.1186/1741-7015-9-87
47. Ins i u o Nacional de Es adís ica. (Na ional S a is ics Ins i u e).
h ps://www.ine.es/dyn 3/inebase/index.h m? ype=pcaxis&pa h=/ 20/e244/ i iendas/p
07/& ile=pcaxis&L=0. Accessed May 29, 2020.
48. Au odesk Building Solu ions. Re i a chi ec u e. 2020. h ps://www.au odesk.com/.
Accessed June 5, 2020.
49. Li H, Chan G, Wong JKW, Ski mo e M. Real- ime loca ing sys ems applica ions in
cons uc ion. Au om Cons . 2016;63:37-47. doi:10.1016/j.au con.2015.12.001
50. Ca u o C, Van Den B oeck W, Ba a A, Colizza V, Pin on J-F, Vespignani A.
Dynamics o Pe son- o-Pe son In e ac ions om Dis ibu ed RFID Senso Ne wo ks.
jou nals.plos.o g. 2010;5(7). doi:10.1371/jou nal.pone.0011596
51. Ma inez-Millana A, Lizondo A, Ga a R, Ve a S, Salcedo VT, Fe nandez-Lla as C.
P ocess Mining Dashboa d in Ope a ing Rooms: Analysis o S a Expec a ions wi h
Analy ic Hie a chy P ocess. In J En i on Res Public Heal A ic. 2019;16(2):199.
doi:10.3390/ije ph16020199
52. Ala i i A, Al-Salman A, Alsaleh M, e al. Ul a Wideband Indoo Posi ioning
Technologies: Analysis and Recen Ad ances. Senso s. 2016;16(5):707.
doi:10.3390/s16050707
53. Pe ukho N, Zamolodchiko V, Zakha o a E, Shamina A. Syn hesis and Compa a i e
Analysis o Cha ac e is ics o Complex Kalman Fil e and Pa icle Fil e in Two-
dimensional Local Na iga ion Sys em. P oc - 2019 U al Symp Biomed Eng
Radioelec on In Technol USBEREIT 2019. 2019;(Me e 2):225-228.
doi:10.1109/USBEREIT.2019.8736683
54. Khan A, Fa nham T, Kou R, e al. S anding on he shoulde s o gian s: AI-d i en
calib a ion o localisa ion echnologies. 2019 IEEE Glob Commun Con GLOBECOM
2019 - P oc. 2019. doi:10.1109/GLOBECOM38437.2019.9013500
55. Raza U, Khan A, Kou R, e al. Da ase : Indoo localiza ion wi h na ow-band, ul a-
wideband, and mo ion cap u e sys ems. DATA 2019 - P oc 2nd ACM Wo k Da a
Acquis To Anal Pa SenSys 2019. 2019:34-36. doi:10.1145/3359427.3361919
56. Jiménez AR, Seco F. Compa ing Ubisense, Bespoon and Decawa e UWB Loca ion
Sys ems: Indoo Pe o mance Analysis.; 2016. doi:10.1109/TIM.2017.2681398