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The effectiveness of a mobile application in enhancing community pharmacists' knowledge of natural herbs and drug interactions

Abstract

Background & Objective: The use of natural herbs is steadily increasing worldwide. This increase has led to a growing number of individuals seeking advice and guidance from community pharmacists on natural herbs. Unfortunately, community pharmacists often lack sufficient knowledge concerning the uses, side effects, and drug interactions of these natural herbs. This study aims to develop and evaluate the quality and effectiveness of a mobile application that focuses on common natural herbs and their interactions with medications, enhancing the knowledge of Syrian community pharmacists. Materilas & Methods: The smartphone application (Herbal Guide) was created and installed on the participants' phones. A quasi-experimental study with a pretest-posttest design was conducted involving twenty-three participants. They completed both tests to evaluate the application's impact on enhancing the knowledge of Syrian community pharmacists. Statistical analysis involved using the paired- t-test to compare pre-test and post-test results, while Cronbach's Alpha was employed to measure the internal consistency of the evaluation questionnaire statements. Results: Ninety-six pharmacists participated in this study, with only twenty-three completing both the pre-test and post-test and meeting the criteria. The application significantly improved the knowledge of Syrian community pharmacists regarding common natural herbs and their interactions with medications. The mean and standard deviation of the participants' results before using the application was 17.56 ± 1.22, compared to 22.04 ± 1.47 after using the application. There was a significant difference in average scores before and after using the application (p = 0.002). There were no statistically significant differences between the average grades of participants and their gender (p = 0.34) or their years of experience (p = 0.10). Most participants found the application easy to use, effective, and characterized by high-quality content and design. Conclusion: The introduction of the new mobile application, "Herbal Guide," resulted in an enhancement of knowledge among Syrian community pharmacists regarding common natural herbs and their interactions with medications, as evidenced by positive feedback from the study participants.

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The effectiveness of a mobile application in enhancing community pharmacists' knowledge of natural herbs and drug interactions

Author: Alkurdi, Kamar; Dashash, Mayssoon; Khatib, Chadi
Publisher: Zenodo
DOI: 10.61882/edcj.18.2.96
Source: https://zenodo.org/records/17255510/files/article-1-2273-en.pdf
Copy igh © 2025 Zanjan Uni e si y o Medical Sciences. Published by Zanjan Uni e si y o Medical Sciences.
This wo k is licensed unde a C ea i e Commons A ibu ion-NonComme cial 4.0 In e na ional license (h ps://c ea i ecommons.o g/licenses/by-
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The e ec i eness o a mobile applica ion in enhancing
communi y pha macis s’ knowledge o na u al he bs and d ug
in e ac ions
Kama Alku di1* , Mayssoon Dashash2, Chadi Kha ib3
1Medical Educa ion Mas e P og am Meded, Sy ian Vi ual Uni e si y SVU, Damascus, Sy ia. & Facul y o Pha macy, Aleppo Uni e si y,
Aleppo, Sy ia
2Depa men o Pedia ic Den is y, Facul y o Den is y, Damascus Uni e si y, Damascus, Sy ia. & Di ec o o he Medical Educa ion
P og am Meded, Sy ian Vi ual Uni e si y SVU, Damascus, Sy ia
3Depa men o Pha macognosy, Facul y o Pha macy, Mana a Uni e si y, La akia, Sy ia. & Facul y o Pha macy, Damascus Uni e si y,
Damascus, Sy ia
A icle in o Abs ac
In oduc ion
Be o e he widesp ead use o mode n medicine, na u al
he bs we e commonly used o ea a ious diseases
h oughou his o y. The ea lies eco ds o using na u al
he bs o medicinal pu poses can be aced back
app oxima ely 5,000 yea s in his o ical ex s om India,
G eece, China, Sy ia, and Egyp . This highligh s he ich
legacy o adi ional he bal he apy ac oss ancien
ci iliza ions [1]. Recen s udies ha e shown a g owing
global in e es in na u al he bs, wi h a ound 70-80% o
he wo ld popula ion u ning o adi ional he bal
medicines o hei p ima y heal hca e needs [2, 3].
Many people belie e in he e ec i eness o na u al he bs
in ea ing a wide ange o diseases, compa ing hem o
chemical medicines. The popula i y o adi ional he bal
emedies can be a ibu ed o hei widesp ead use among
pa ien s and hei accessibili y. Mos people iew na u al
A icle his o y:
Recei ed 14 Sep. 2024
Accep ed 3 Jun. 2025
Published 13 Jul. 2025
Alku di e al. J Med Edu De . 2025; 18(2): 96-104 Jou nal o Medical Educa ion De elopmen
Backg ound & Objec i e: The use o na u al he bs is s eadily inc easing wo ldwide. This
inc ease has led o a g owing numbe o indi iduals seeking ad ice and guidance om
communi y pha macis s on na u al he bs. Un o una ely, communi y pha macis s o en lack
su icien knowledge conce ning he uses, side e ec s, and d ug in e ac ions o hese na u al
he bs. This s udy aims o de elop and e alua e he quali y and e ec i eness o a mobile
applica ion ha ocuses on common na u al he bs and hei in e ac ions wi h medica ions,
enhancing he knowledge o Sy ian communi y pha macis s.
Ma e ials & Me hods: The sma phone applica ion (He bal Guide) was c ea ed and ins alled
on he pa icipan s' phones. A quasi-expe imen al s udy wi h a p e es -pos es design was
conduc ed in ol ing wen y- h ee pa icipan s. They comple ed bo h es s o e alua e he
applica ion's impac on enhancing he knowledge o Sy ian communi y pha macis s. S a is ical
analysis in ol ed using he pai ed- - es o compa e p e- es and pos - es esul s, while
C onbach's Alpha was employed o measu e he in e nal consis ency o he e alua ion
ques ionnai e s a emen s.
Resul s: Nine y-six pha macis s pa icipa ed in his s udy, wi h only wen y- h ee comple ing
bo h he p e- es and pos - es and mee ing he c i e ia. The applica ion signi ican ly imp o ed
he knowledge o Sy ian communi y pha macis s ega ding common na u al he bs and hei
in e ac ions wi h medica ions. The mean and s anda d de ia ion o he pa icipan s' esul s
be o e using he applica ion was 17.56 ± 1.22, compa ed o 22.04 ± 1.47 a e using he
applica ion. The e was a signi ican di e ence in a e age sco es be o e and a e using he
applica ion (p < 0.01). The e we e no s a is ically signi ican di e ences be ween he a e age
g ades o pa icipan s and hei gende (p > 0.05) o hei yea s o expe ience (p > 0.05). Mos
pa icipan s ound he applica ion easy o use, e ec i e, and cha ac e ized by high-quali y
con en and design.
Conclusion: The in oduc ion o he new mobile applica ion, "He bal Guide," esul ed in an
enhancemen o knowledge among Sy ian communi y pha macis s ega ding common na u al
he bs and hei in e ac ions wi h medica ions, as e idenced by posi i e eedback om he s udy
pa icipan s.
Keywo ds: mobile applica ion, na u al common he bs, medical educa ion, communi y
pha macis s, d ug in e ac ions
*Co esponding au ho :
Kama Alku di, Medical Educa ion
Mas e P og am Meded, Sy ian Vi ual
Uni e si y SVU, Damascus, Sy ia. &
Facul y o Pha macy, Aleppo Uni e si y,
Aleppo, Sy ia.
Email:0533665281kama @gmail.com
O iginal A icle
How o ci e his a icle:
Alku di K, Dashash M, Kha ib Ch.
The e ec i eness o a mobile
applica ion in enhancing communi y
pha macis s’ knowledge o na u al
he bs and d ug in e ac ions. J Med
Edu De . 2025; 18(2): 96-104.
[ DOI: 10.61882/edcj.18.2.96 ] [ Downloaded om edujou nal.zums.ac.i on 2025-10-03 ]
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he bs as sa e al e na i es o chemical medicines due o
hei na u al o igins [4]. Howe e , some use hese na u al
he bs as supplemen s wi hou consul ing heal hca e
p o essionals [5], which can pose isks, including
in e ac ions wi h pha maceu ical p epa a ions [6].
Addi ionally, i is impo an o no e ha he Food and
D ug Adminis a ion (FDA) does no classi y na u al
he bs and he bal p epa a ions as d ugs. Unde he
Educa ion and Heal h Ac o Die a y Supplemen s o
1994, die a y supplemen s like i amins, mine als, he bs,
o plan s (excluding obacco) a e conside ed dis inc
om ood and a e in ended o human consump ion only.
As a esul , he sa e y and e icacy o na u al he bs and
he bal p epa a ions emain unclea . Communi y
pha macis s play a c ucial ole as heal hca e p o ide s
and in deli e ing op-quali y pha maceu ical ca e
se ices [7]. They a e in ol ed in a ious a eas, such as
ensu ing pa ien s adhe e o hei p esc ibed medica ions,
o e ing counselling, educa ing pa ien s on he uses o
na u al he bs, and in o ming hem abou possible
in e ac ions [8]. Resea ch in ol ing se e al s udies [9,
10, 11] indica ed ha ce ain communi y pha macis s
lack su icien in o ma ion ega ding he side e ec s,
p ecau ions, and in e ac ions o he bal p oduc s. They
equi e eliable esou ces and knowledge o p o ide
e idence-based ad ice o hei cus ome s [12]. Sy ia is
dis inc i e o he ichness o i s ege a ion and i s
species di e si y; he u ban and u al popula ions s ill
ely on adi ional he bal emedies o he ea men o
a ious diseases [13, 14]. Addi ionally, he use o
common he bs o ea men has become mo e
widesp ead due o hei a o dabili y, accessibili y, and
cos -e ec i eness. Unlike physician consul a ions,
which may in ol e cos s and long wai ing imes, Sy ian
communi y pha macis s ypically o e ee and
immedia e ad ice. Consequen ly, Sy ian pha macis s a e
inc easingly ielding inqui ies abou na u al he bs. The
pha macy cu icula in Sy ian uni e si ies include
pha macognosy and phy ochemis y cou ses, which a e
augh in dep h s a ing om he hi d academic yea .
These cou ses aim o p o ide g adua ed pha macis s wi h
essen ial compe encies ela ed o he o igin, ac i e
ing edien s, and physiological e ec s o medical plan s
a he han ocusing solely on hei side e ec s and
in e ac ions wi h medica ions. Fu he mo e, many Sy ian
communi y pha macis s ha e been in e nally displaced
o eloca ed due o he Sy ian c isis. This has in e up ed
hei access o con inuous educa ion p og ams, esul ing
in a knowledge gap among communi y pha macis s.
Se e al s udies conduc ed in Sy ia ac oss a ious
medical ields ha e p o ided e idence ha in eg a ing
in o ma ion echnology in o medical educa ion can esul
in g ea e educa ional oppo uni ies o medical s uden s
and heal hca e p o essionals. The in eg a ion o
knowledge acili a es acquisi ion, imp o es decision-
making, enhances psychomo o skills, and p omo es he
de elopmen o new ideas and concep s [15-18].
Addi ionally, in o ma ion echnology can be conside ed
an e ec i e adjunc ool ha can o e high-quali y
medical educa ion in con lic zones [19]. Fu he mo e,
online medical educa ion can yield posi i e ou comes
e en in esou ce-limi ed communi ies, p o ided ha he
educa ional ma e ials a e ailo ed o he needs, language,
and cul u e o he heal hca e p o ide s. Addi ionally,
de eloping and e alua ing he scien i ic con en by local
medical educa o s who a e amilia wi h hese ac o s can
lead o imp o ing he e ec i eness and use ulness o
online medical educa ion [20]. In his ega d, sma phone
applica ions ha e a posi i e impac on enhancing
knowledge and skills among heal hca e p o essionals
ac oss a ious heal h opics and con ex s. Mobile
applica ions a e e ec i e adjunc ools in medical
educa ion due o hei low cos and high e sa ili y [21,
22]. In his con ex , educa ional mobile applica ions on
pha maceu ical opics would be c ucial o pha macis s,
p o iding hem wi h su icien in o ma ion and assis ing
hem in b idging he knowledge gap. Howe e , he
li e a u e emains limi ed ega ding he e ec i eness o
sma phone educa ional applica ions in enhancing he
knowledge o communi y pha macis s in Sy ia.
The e o e, his s udy aimed o de elop and e alua e he
impac o a mobile applica ion designed o enhance he
knowledge o Sy ian communi y pha macis s ega ding
na u al he bs and hei in e ac ions wi h medica ions.
This assessmen was conduc ed h ough p e- and pos -
in e en ion es s, as well as a ques ionnai e o e alua e
he applica ion's quali y, e iciency, and ease o use.
Ma e ials & Me hods
Design and se ing(s)
This s udy employed a quasi-expe imen al design wi h a
p e- es and pos - es conduc ed on a andomized g oup
o Sy ian communi y pha macis s en olled in he Sy ian
Pha macis s' Associa ion in Sy ian ci ies in Decembe
2022.
Pa icipan s and sampling
The sample size consis ed o 96 communi y pha macis s
om a ious loca ions in Sy ia, selec ed using a
con enience sampling me hod. Eligible pa icipan s
we e pha macis s wo king in communi y pha macies in
Sy ia who me he inclusion c i e ia o pa icipa ion in
his s udy. The sample size was calcula ed using Fo mula
A, wi h a 95% con idence le el and an 80% s a is ical
powe . The mean and s anda d de ia ion pa ame e s
we e also de e mined.
𝐅𝐨𝐫𝐦𝐮𝐥𝐚 𝐀: 𝑛 = 𝑍2𝑝(1−𝑝)
𝑑2
To ec ui a la ge sample, pha macis s we e in o med
abou he de eloped applica ion and i s unique ea u es,
as well as he s udy's pu pose and p ocedu e h ough
ad e isemen on social media pla o ms wi h signi ican
pha macis membe ship. Addi ionally, o u he
inc ease he sample size, ex a communi y pha macis s
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we e con ac ed a hei pha macies in di e en Sy ian
ci ies. The esponses om Pha macis s who exp essed
in e es in he applica ion, accep ed pa icipa ion in he
s udy, and me he inclusion c i e ia we e analyzed by he
main esea che o con i m hei eligibili y. The inclusion
c i e ia equi ed pha macis s o be licensed in he Sy ian
A ab Republic, employed in communi y pha macies,
hold a leas a bachelo 's deg ee o a highe quali ica ion,
and be willing o olun a ily pa icipa e in his
s udy. The exclusion c i e ia included pha macy
pe sonnel wo king in o he sec o s, such as hospi als,
indus y, and academia (Figu e 1). The s udy in ol ed
23 eligible pha macis s (16 emale, se en male).
In o ma ion collec ed om he pa icipa ing pha macis s
includes age, gende , yea s o expe ience, and he
uni e si y om which hey g adua ed. The pe sonal
in o ma ion was compiled and sen o he p og am
coo dina o , who hen p o ided an elec onic link o
download he applica ion, along wi h an ins uc ional
ideo explaining egis a ion s eps and how o use he
applica ion.
Figu e 1. CONSORT diag am o pa icipan s eligible, d opped ou , numbe s ollowed up and included in analysis
Tools/Ins umen s
The s udy comp ised wo phases: he ini ial phase
in ol ed he c ea ion and de elopmen o he
applica ion. In con as , he subsequen phase ocused on
e alua ing he applica ion's e ec i eness in enhancing
pha macis s' knowledge o common he bal emedies and
hei in e ac ions wi h medica ions. Addi ionally, he
s udy in ol ed e alua ing he quali y o he applica ion's
con en , design, and usabili y. The i s phase o his
s udy ook place be o e he in e en ion, du ing which
he scien i ic con en o he applica ion was de eloped by
he p ima y esea che . This de elopmen d ew on he
Physicians' Desk Re e ence (PDR) - Fou h Edi ion o
Medicinal He bs, as well as ele an in e na ional a icles
and publica ions a ailable on PubMed. The selec ion o
common na u al he bs included in he applica ion was
based on hei popula i y and demand in pha macies in
he Sy ian A ab Republic. The con en was e ined
h ough ocused discussions wi h supe ising p o esso s
who ac ed as a bi a o s o de e mine he sessional
con en o be included in he applica ion. The scien i ic
con en was alida ed by MD, a acul y membe and an
expe in medical educa ion, and CK, a acul y membe
a he Sy ian Pha macy College and an expe in
pha macognosy and phy ochemis y. They ensu ed he
con en was aligned wi h c i ical in o ma ion om he
Sy ian pha macy cu icula and hei p ac ical
expe iences. (addi ional de ails can be ound in
Appendix 1). A e ecei ing he app o al, he
sma phone applica ion "He bal Guide" was speci ically
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de eloped o sma phones ope a ing on he And oid o
iOS sys ems. The design, p og amming, and es ing
phases las ed app oxima ely wo mon hs, du ing which
he de elopmen eam p o ided he esea che wi h a ial
e sion o he applica ion on a weekly basis o ensu e ha
he e we e no echnical o scien i ic e o s. The p e-and
pos - es s we e designed in A abic o assess he
knowledge le el o pa icipan s and pha macis s be o e
engaging wi h he applica ion and o de e mine whe he
i had imp o ed a e use. The p e- es was designed in
alignmen wi h he pu pose o which he applica ion was
de eloped. Addi ionally, he es consis ed o a se ies o
ques ions co e ing he uses o commonly ound na u al
he bs, po en ial con aindica ions, side e ec s, and
in e ac ions wi h d ugs o assess he pa icipan s'
knowledge be o e engaging wi h he applica ion. The
assessmen con ained wen y- i e ques ions. Fi een
ques ions we e in a mul iple-choice o ma , and en
ques ions ollowed a ue o alse empla e (Appendix
2). The p e- es was adminis e ed immedia ely a e
egis a ion o he applica ion and be o e he con en was
displayed. Upon comple ion o he p e- es ques ions,
pa icipan s we e asked o submi hei esponses ia e-
mail o he esea che . Subsequen ly, he second phase o
his esea ch in ol ed implemen ing he in e en ion. In
his phase, he applica ion's con en ea u es a collec ion
o amilia na u al he bs. Each he b was accompanied by
an illus a i e image, i s scien i ic name in A abic and
English, and a sea ch ool a he op o he sc een. Each
he b is p esen ed on a sepa a e sc een, including
in o ma ion such as he scien i ic name, medicinal pa ,
he apeu ic p ope ies, con aindica ions, side e ec s,
p ominen d ug in e ac ions, and e e ences. The
applica ion was used o h ee weeks, du ing which he
esea che ac i ely encou aged and eminded
pa icipan s o use i h ough a Wha sApp g oup. The
esea che p o ided guidance on comple ing he pos -
es . The applica ion ea u ed an e alua ion icon nex o
each he b; when clicked, i di ec ed use s o he pos - es ,
which eplica ed he ques ions om he p e- es . This
pos - es was adminis a ed immedia ely a e wen y-
one days o using he applica ion, and pa icipan s
submi ed hei esponses ia e-mail o he esea che .
The maximum possible sco e o each es was wen y-
i e. Addi ionally, a eedback ques ionnai e was
included in he pos - es o e alua e he con en quali y,
design e ec i eness, and use - iendliness o he
applica ion. This ques ionnai e was s uc u ed in h ee
sec ions, each con aining en s a emen s a ed on a i e-
poin Like scale, whe e one indica ed "s ongly
disag ee," wo ep esen ed "disag ee," 3 was "unsu e," 4
s ood o "ag ee" and i e deno ed "s ongly ag ee"
(Appendix3). To assess in e nal consis ency, C onbach's
alpha coe icien was applied o he ques ionnai e i ems.
The i s sec ion sco ed 0.81, he second sec ion 0.69,
and he hi d sec ion 0.78. Values ange om 0 o 1, wi h
an accep able h eshold in social s udies being 0.60.
These esul s indica e ha he ques ionnai e is eliable,
alid, and hones . Con en and ace alidi y we e
checked and examined by he supe iso , MD, who is an
expe in he medical educa ion ield. Addi ionally, he
mean and s anda d de ia ion we e used o analyze he
dis ibu ion o esponses o each i em, p o iding
insigh s in o pa icipan s' sa is ac ion.
Da a collec ion me hods
Be o e hei pa icipa ion, in o med consen was
ob ained om all pa icipan s. The consen o m, w i en
in A abic, p o ided a clea desc ip ion o he s udy
objec i es and p ocedu es. Pa icipan s we e assu ed ha
hei pe sonal in o ma ion would be secu ely s o ed and
solely used in his s udy. A basic ins uc ional ideo was
p epa ed and dis ibu ed o 96 pa icipan s, explaining
egis a ion s eps and how o use he applica ion as he
i s s ep o his s udy. A o al o 23 pa icipan s who me
he inclusion c i e ia ag eed o ake pa in he s udy.
Da a analysis
Only he esul s om pa icipan s who comple ed all
s udy p ocedu es we e included. Da a om he p e-and
pos - es s we e o ganized in Excel 2019. A one- ailed
pai ed - es was pe o med o assess di e ences be ween
he p e-and pos - es esul s wi h a signi icance le el se
a p < 0.05. Desc ip i e s a is ics, including mean and
SD, we e u ilized o analyze he s udy ou comes. A i e-
poin Like scale was implemen ed as a ques ionnai e o
assess he quali y, e iciency, and ease o use o he
applica ion. The mean and S anda d De ia ion o each
s a emen we e collec ed on a scale o 1 o 5. C onbach's
Alpha was employed o measu e he in e nal consis ency
o he ques ionnai e.
Resul s
A o al o 96 Sy ian communi y pha macis s pa icipa ed
in he s udy, comp ising 22 men and 47 women. The
pa icipan s' ages anged be ween wen y- wo and i y
yea s, wi h hei yea s o expe ience spanning om one
o hi y yea s. The majo i y o pa icipan s, o aling 72,
g adua ed om public uni e si ies, while 24 g adua ed
om p i a e uni e si ies. A o al o wen y- h ee
pa icipan s (16 emales, ep esen ing 69.6%, and se en
males, ep esen ing 30.4%) me he c i e ia and we e
in i ed o olun a ily pa icipa e in his s udy. The esul s
showed a signi ican imp o emen in pa icipan s'
knowledge ollowing he use o he He bal Guide
applica ion. The a e age sco e in he p e- es s was 17.5,
which signi ican ly inc eased o an a e age o 22.04 in
he pos - es s, indica ing a s a is ically signi ican
imp o emen (p = 0.002). Fu he mo e, he s anda d
de ia ion in p e- es sco es was lowe han ha o he
pos - es sco es. De ailed esul s can be ound in (Table
1). Twen y- h ee pa icipan s comple ed he e alua ion
ques ionnai e. The majo i y o hem desc ibed using he
applica ion in a posi i e manne . They mos ly ag eed
wi h he posi i e s a emen s ha gauged he applica ion's
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quali y, e iciency, and ease o use. O e all sa is ac ion
wi h bo h he applica ion's con en and design was high.
All pa icipan s ag eed on se en ou o en s a emen s
ela ed o he con en , wi h one pa icipan sugges ing a
eminde ea u e o pha macis s who may o e look
ce ain in o ma ion. O e 85% o he pa icipan s ag eed
wi h he s a emen s. Some pa icipan s el ha he
scien i ic con en could be p esen ed in a mo e o ganized
and clea manne o exp essed a desi e o mo e no el
in o ma ion a he han a summa y o exis ing
knowledge. Rega ding he design e alua ion, all
pa icipan s ag eed wi h six s a emen s, wi h mos also
ag eeing wi h he emaining ones. Howe e , he e we e
di e ing opinions on ce ain aspec s, like po en ial
addi ions o he applica ion. E e yone ound he He bal
Guide applica ion simple and use - iendly. Many
p aised i s simplici y, belie ing i o be accessible o all.
Pa icipan s unanimously acknowledged he
applica ion's po en ial o imp o e pha maceu ical
se ices and ecommended i o hei pee s. They also
ecognized i s p ac icali y o daily p ac ice. Mo e han
90% o pa icipan s el ha he applica ion adequa ely
mee s i s in ended pu pose. Some pa icipan s,
pa icula ly hose wi h ex ensi e expe ience, no ed a eas
o imp o emen , such as ca e ing o less expe ienced
pha macis s, inco po a ing mo e commonly used he bs,
and p o iding in o ma ion on he bal mix u es. De ails o
he analysis can be ound in Table 2. The in e nal
consis ency o he ques ionnai e s a emen s was
e alua ed using C onbach's alpha coe icien , wi h sco es
o 0.81 o he i s sec ion, 0.69 o he second sec ion,
and 0.78 o he hi d sec ion.
Table 1. Compa ison o pa icipan s’ sco es be o e and a e
he in e en ion
Resul s o
pa icipan s
n
Mean ± SD
Minimum
Maximum
Be o e he
in e en ion
23
17.56 ± 1.22
15
20
A e he
in e en ion
23
22.04 ± 1.47
20
24
P-Value
0.002
No e: A pai ed - es was used o compa e pa icipan s’ sco es be o e and a e
he in e en ion.
Abb e ia ions: n, numbe o pa icipan s; SD, s anda d de ia ion; p, p obabili y-
alue.
Table 2. Pa icipan s’ esponses o s a emen s assessing he applica ion’s con en , design, e iciency, and ease o use
S a emen s
Ag eemen
Mean
SD
Applica ion's con en
1. The con en is ele an o he applica ion's de elopmen objec i es.
100%
4.17
0.38
2. The con en is scien i ically accu a e and up- o-da e.
100%
4.13
0.34
3. The con en akes in o accoun pha macis s’ p io knowledge.
100%
4.26
0.44
4. The con en is o ganized in a clea and logical manne .
91.31%
4.06
0.54
5. The language and e minology used a e unde s andable and amilia .
100%
4.21
0.42
6. The con en connec s new in o ma ion o exis ing knowledge.
91.3%
4
0.60
7. Pha macis s can independen ly access he in o ma ion.
100%
4.26
0.44
8. The con en is s uc u ed o acili a e knowledge acquisi ion.
86.9%
3.91
0.62
9. The con en is comp ehensi e and di ec ly ele an o commonly used na u al he bs.
100%
4.30
0.47
10. The con en is co ec and based on app o ed scien i ic e e ences.
100%
4.27
0.44
Applica ion's design
11. Na iga ion be ween he main and sub-pages is easy and in ui i e.
100%
4.17
0.38
12. The main and sub-pages a e isually appealing and consis en .
100%
4.26
0.44
13. The applica ion’s design acili a es con en sea ch and access.
91.3%
4
0.60
14. The applica ion allows he de elope o upda e and add new he bs.
86.9%
3.86
0.45
15. The in o ma ion is p esen ed in a way ha suppo s quick access.
100%
4.26
0.44
16. The applica ion includes ins uc ions o help use s access con en .
100%
4.21
0.42
17. The con en is p esen ed in a way ha conside s p io knowledge.
95.6%
3.95
0.59
18. The con en is clea , easy o ead, and dis inguishes be ween headings and subheadings.
100%
4.17
0.38
19. The applica ion a oids o e sized images o con en .
86.9%
3.91
0.62
20. The colo s and backg ound used in he applica ion a e calm and sui able.
100%
4.26
0.44
Applica ion's e e iciency and ease o use
21. Na iga ion wi hin he applica ion is smoo h and use - iendly.
100%
4.17
0.38
22. The in e ace design is appealing and consis en h oughou .
100%
4.26
0.44
23. The s uc u e acili a es easy sea ch and access o he con en .
91.3%
4
0.60
24. The app suppo s upda es and addi ions by he de elope .
86.9%
3.86
0.45
25. In o ma ion is displayed in a o ma ha aids use na iga ion.
100%
4.26
0.44
26. The applica ion p o ides clea guidance o con en access.
100%
4.21
0.42
27. The p esen a ion o con en e lec s use s’ exis ing knowledge.
95.6%
3.95
0.59
28. The ex is easy o ead and s uc u ed wi h clea headings.
100%
4.17
0.38
29. The app a oids la ge-sized isuals o unnecessa y in o ma ion.
86.9%
3.91
0.62
30. Backg ound and colo schemes a e calming and app op ia e.
100%
4.26
0.44
No e: Desc ip i e s a is ics we e used o assess pa icipan s’ ag eemen wi h each s a emen ega ding he applica ion’s quali y, con en , and usabili y.
Abb e ia ions: SD, s anda d de ia ion; %, pe cen age.
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Discussion
The g owing use o common na u al he bs highligh s he
necessi y o communi y pha macis s o possess
knowledge abou hese he bs. They should also be
equipped o o e e ec i e guidance on hei uses and
po en ial isks. Addi ionally, he ole o pha macis s has
e ol ed om me ely dispensing medica ions o
p o iding ad anced se ices [23]. This shi equi es
hem o main ain p o essionalism, s ay upda ed on he
la es echnologies and in o ma ion, and deli e high-
quali y pha maceu ical se ices. Mobile echnologies
ha e a signi ican impac on he deli e y o heal hca e
se ices, enhancing he quali y o heal h se ices [24].
Mobile applica ions se e as e ec i e ools o
enhancing knowledge and a e aluable aids in educa ion,
cha ac e ized by hei di e se na u e, low de elopmen
cos , ease o upda es, and lexible lea ning ea u es [22].
U iliza ion o mobile applica ions in medical educa ion
p esen s se e al oppo uni ies ha acili a e heal hca e
p o essionals in hei educa ional endea o s.
Fu he mo e, hey can be ega ded as a eliable and
e ec i e solu ion in c ises wi h limi ed esou ces and
uns able en i onmen s, such as in Sy ia [19, 20]. As
s a ed ea lie , he applica ion was c ea ed o p o ide
Sy ian communi y pha macis s wi h a p ope app oach
o expanding hei knowledge o common na u al he bs
and hei po en ial d ug in e ac ions and o se e as a
e e ence ool when necessa y. Analysis o he s udy
esul s e ealed ha he applica ion e ec i ely imp o ed
pa icipan s' knowledge o common na u al he bs and
hei in e ac ions wi h medica ions. The e was a
signi ican di e ence in he esul s o he pa icipan s
be o e and a e using he mobile applica ion, wi h a
s a is ically signi ican p < 0.05. These indings align
wi h he s udies o Mikhael and colleagues [25] and
Payda and colleagues [26], who also ound a posi i e
impac o sma phone applica ions on enhancing
communi y pha macis s' knowledge, imp o ing
pha maceu ical se ices, and enhancing hei
managemen o common mino diseases. Addi ional
s udies ha e also discussed he e ec i eness o
sma phone applica ions in enhancing he knowledge o
heal h p o essionals.
Alsha i and colleagues [27] indica ed ha sma phone
apps a e accessible and e ec i e educa ional ools o
b idging he knowledge gap o MR adiog aphe s and
suppo ing hem in ecognizing and cha ac e izing MR
image quali y e o s. This esul also ag ees wi h Smania
[28], who add essed he posi i e impac o mobile
lea ning applica ions on enhancing he knowledge and
con idence o nu se p ac i ione s ega ding BReas
CAnce gene 1 (BCRA) mu a ion, a isk ac o o
de eloping ce ain ypes o cance in women. Simila
indings we e no ed by Ponce and colleagues [29].
Resea che s ound ha ana omic sma phone
applica ions a e e ec i e in imp o ing he knowledge
and pe o mance o pa icipan s.
The p e- es esul s o his s udy indica ed ha
pa icipan s s uggled wi h ques ions p ima ily ocused
on d ug in e ac ions, ad e se e ec s, and p ecau ions
ela ed o na u al he bs, sugges ing a lack o knowledge
in his a ea. Simila indings we e obse ed in s udies
conduc ed in Lebanon and Pales ine [31, 32], whe e
communi y pha macis s demons a ed knowledge o
na u al he b uses. S ill, hei unde s anding o side e ec s
and d ug in e ac ions was limi ed. This unde sco es he
impo ance o enhancing pha macis s ' knowledge
conce ning he side e ec s and in e ac ions o common
na u al he bs. Fu he mo e, he e is a g ea e need o
eliable sou ces o in o ma ion on common na u al he bs
and he inclusion o pha macy aining p og ams in his
domain; his was simila ly epo ed by Ca and
colleagues and Abahussain and colleagues [30, 31]. In
con as , pa icipan s excelled a answe ing ques ions
ela ed o he medicinal pa s, p ope ies, and uses o
he bs. This p o iciency can be a ibu ed o ecen
g adua es' amilia i y wi h his in o ma ion om hei
ea lie yea s o s udy. Addi ionally, expe ienced
pha macis s likely acqui ed his knowledge h ough
con inuous educa ion p og ams and semina s on
common na u al he bs p o ided by he Sy ian
Pha macis s' Associa ion. The s udy also explo ed he
ela ionship be ween gende and he mean scaled sco es
be o e and a e using he applica ion bu ound no
signi ican s a is ical di e ence (p- alue = 0.34).
Simila ly, compa ing pa icipan s ' yea s o expe ience
(< 10 o > 10 yea s) did no esul in inc eased mean
scaled sco es (p > 0.05). Ne e heless, he indings
indica ed ha pa icipan s we e sa is ied wi h he
scien i ic con en , design, and use - iendliness o he
applica ion, demons a ing a clea p e e ence o he
mobile applica ion. This ag eed wi h he esul s o
se e al s udies [32, 33, 34], which epo ed ha
pha macis s exhibi a keen in e es in le e aging
in o ma ion echnology wi hin hei daily p ac ices and
p e e elec onic applica ions o e adi ional pape
e e ences due o hei quick access o in o ma ion, ease
o use, and egula upda es. Howe e , upon u he
analysis o each sec ion, i was obse ed ha he design
sec ion ecei ed he lowes a ing o 4.1 ou o 5.
Fu he mo e, he o ganiza ion o he applica ion con en
in he ini ial sec ion o he e alua ion ques ionnai e
ecei ed he leas sa is ac ion. This may be explained by
he ac ha he esea che hea ily elies on he PDR
e e ence o he p epa a ion o he con en , which se es
as a p ima y esou ce o pha macognosy and
pha macognosy chemis y cou ses in mos Sy ian
pha macy schools. This eliance migh ha e led
pa icipan s o belie e ha he applica ion did no o e
new in o ma ion. Mo eo e , he abili y o upda e he
applica ion and include new he bs ecei ed he lowes
sa is ac ion, likely because he esea che ailed o
in o m pa icipan s abou his ea u e.
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Addi ionally, he p ocess o accessing he con en , which
in ol ed se e al s eps, ecei ed he lowes a ing.
Pa icipan s may ha e aced di icul ies logging in and
accessing he applica ion's con en , pa icula ly since i
equi ed he ins alla ion o ce ain p og ams. The
esea che did no cla i y his de ail, as he login p ocess
using email and he p e- es we e in ended solely o
esea ch pu poses.
I should be emphasized ha pa icipan s in his s udy
we e limi ed o hose in e es ed in enhancing hei
knowledge o common na u al he bs and hei
in e ac ions wi h d ugs. Fu u e s udies should conside a
la ge sample size o con i m hese indings.
Addi ionally, i is wo h no ing ha his s udy has o he
limi a ions, including he limi ed ime ame wi hin
which i was conduc ed. The esul s o knowledge abou
common na u al he bs and hei d ug in e ac ion
ep esen sho - e m knowledge gain a he han long-
e m e en ion.
The e o e, u u e wo k should conside long- e m
e en ion. Addi ionally, he selec ed he bs we e he mos
popula in Sy ia, and i is possible ha some pa icipan s
we e mo e knowledgeable abou o he he bs.
Conclusion
The indings o he p esen s udy demons a ed ha he
He bal Guide applica ion signi ican ly imp o ed
communi y pha macis s' knowledge ega ding common
na u al he bs and hei po en ial d ug in e ac ions. They
ecei ed i well.
Addi ionally, na u al he bs should be inco po a ed in o
he applica ion o enhance i s e ec i eness.
E hical conside a ions
E hical app o al was ob ained om he E hical Resea ch
Commi ee o he Sy ian Vi ual Uni e si y (SVU),
unde Numbe 4015 0, da ed Augus 2, 2022.
A i icial in elligence u iliza ion o a icle
w i ing
No.
Acknowledgmen
The au ho s would like o hank all pha macis s who
pa icipa ed in his s udy and e e yone who p o ided
sugges ions ha helped imp o e i .
Con lic o in e es s a emen
The au ho s decla e ha hey ha e no known compe ing
inancial in e es s o pe sonal ela ionships ha could
ha e appea ed o in luence he wo k epo ed in his
manusc ip .
Au ho con ibu ions
KA is he p incipal esea che who collec ed pa icipan s'
g oups and da a, p epa ed he scien i ic con en o he
mobile applica ion, and analyzed he esul s. Bo h MD
and CK supe ised he s udy and e ised he scien i ic
con en o he mobile. Bo h KA and MD pa icipa ed in
choosing he idea o his s udy, as well as w i ing and
e ising he manusc ip be o e submission. All au ho s
ead and app o ed he inal manusc ip .
Funding
This s udy is pa o a hesis o ob ain mas e deg ee in
medical educa ion and is suppo ed by he Sy ian Vi ual
Uni e si y.
Da a a ailabili y s a emen
The da a ha suppo he indings o his s udy a e
a ailable om he co esponding au ho , K. Alku di,
upon easonable eques .
Appendixes
Appendix 1
h ps://d i e.google.com/ ile/d/1GaGWqVUMq4g61ha
O_C UdeE53 5GzBBM/ iew?usp=sha e_link
Appendix 2
h ps://d i e.google.com/ ile/d/1QOiPzjbKHkchWN_Qi
2XhNSW4OwwUaNg7/ iew?usp=sha e_link
Appendix 3
h ps://d i e.google.com/ ile/d/1dWzRPpo_1SD58ZIJc
yOu3AjLqRWk-iIM/ iew?usp=sha e_link
Supplemen a y ma e ial
De eloping company: h ps://gul dimension.com/
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