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Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE “MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS”
TASHKENT, OCTOBER 17, 2025
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STUDY OF THE DYNAMICS OF ALCOHOL EXTRACTION OF PHYSALIS
ANGULATA
Bayniyazo A.J.
Jumaniyazo Sh.I.
Bax iyo o J.G.
Abdu axmano B.A.
So imo G.B.
Egamo a F.R.
Ins i u e o he Chemis y o Plan Subs ances named a e Acad. S.Yu. Yunuso , Tashken ci y,
Uzbekis an
e-mail: [email p o ec ed] [email p o ec ed]
h ps://doi.o g/10.5281/zenodo.17322491
Rele ance: Physalis angula a (angula physalis) is an e ec annual he baceo us plan o he
Solanaceae amily. The lea es a e da k g een, almos o a e, o en wi h se a ed edges. The lowe s
a e pen agonal, pale yellow; he yellow-o ange ui s a e enclosed in a sphe ical calyx [1]. Physalis
angula a (P. angula a L.) was i s disco e ed and eco ded in he lo a o Libya [2]. The species may
be a na u al endemic o Aus alia o Ame ica, o i s ange may co e bo h Ame ica and Aus alia. A
p esen , i is widesp ead and na u alized in opical and sub opical egions h oughou he wo ld.
Pe ennial he baceous plan s wi h hick unb anched s ems co e ed wi h al e na e scales. The
lowe s a e collec ed in spike-like clus e s. Plan s o his genus pa asi ize he oo s o sh ubs and
semi-sh ubs.
Physalis angula a is adi ionally used o i s an ibac e ial, an i-in lamma o y, and analgesic
p ope ies. Va ious s udies ha e also demons a ed i s an imala ial, an ias hma ic, an idiabe ic,
an ioxidan , and an icance po en ial [3]. Physalin con ained in his plan is being s udied o i s
an icance and an imic obial ac i i y.
F om he li e a u e, i is known ha s e oidal lac ones (physalins) ound in Physalis angula a
ha e shown an i umo ac i i y in i o agains se e al cance cell lines. Physalin compounds such as
physalin B, D, and F ha e demons a ed an ibac e ial ac i i y agains a ious bac e ia, including
S aphylococcus au eus and Esche ichia coli. S udies con i m he plan ’s abili y o educe
in lamma ion by inhibi ing a ious in lamma o y pa hways.
Objec i e. The pu pose o his s udy is o in es iga e he dynamics o alcohol ex ac ion om
Physalis angula a.
Ma e ials and Me hods. The dynamics o subs ance ex ac ion om plan ma e ial we e
s udied as ollows: 0.5 kg o c ushed aw ma e ial was loaded in o se en ex ac o s (5 L capaci y
each) and illed wi h he selec ed sol en un il a “mi o ” o med. Ex ac ion was ca ied ou a oom
empe a u e.
The ex ac s we e d ained sequen ially a in e als o 1 hou . Thus, in he i s ex ac o he
ex ac ion las ed 1 hou , in he second – 2 hou s, in he hi d – 3 hou s, in he ou h – 4 hou s, in he
i h – 5 hou s, in he six h – 6 hou s, and in he se en h – 7 hou s.
A e he se ime, he ex ac s we e d ained, and he yield o ex ac i e subs ances was
de e mined. By analyzing he esul s, phase equilib ium was es ablished depending on he soaking
ime du ing he i s con ac .
Resul s. Based on he esea ch esul s, i was es ablished ha by he i h con ac he yield o
ex ac i e subs ances was insigni ican (0.4% o he aw ma e ial mass). A e h ee d ainings, he
ex ac ion deg ee eached 90.3%, which is qui e accep able o he ex ac ion s age.
105
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE “MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS”
TASHKENT, OCTOBER 17, 2025
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Conclusions. F om his, we ecommend iple ex ac ion. The equi ed soaking ime a he i s
phase con ac is 6 hou s, while a he second and hi d con ac s phase equilib ium is eached wi hin 4
hou s.
