127
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE “MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
MEDICINES FOR CHILDREN
Khadjime o a S.R.1
Ka ie a Y.S.2
Tashken Pha maceu ical Ins i u e, Tashken ci y, Republic o Uzbekis an
e-mail: [email p o ec ed]
h ps://doi.o g/10.5281/zenodo.17325031
Rele ance: The limi ed ange o pedia ic medica ions and he o ms in which hey a e
p oduced p omp ed he Fi s In e na ional Expe Con e ence on Essen ial Medicines o Child en o
be held in Gene a in 2006. In addi ion o scien is s om 20 coun ies, ep esen a i es o in e na ional
o ganiza ions such as he Wo ld Heal h O ganiza ion (WHO) and he Uni ed Na ions Child en's Fund
(UNICEF) pa icipa ed. Since hen, esea ch has been conduc ed wo ldwide o de elop specialized
pedia ic dosage o ms, add ess sa e y issues, implemen a special app oach o he selec ion o
excipien s, and conside age- ela ed medica ion es ic ions, as well as he ana omical and
physiological cha ac e is ics o child en.
The objec i e o he s udy was o analyze da a on pedia ic dosage o ms and o examine issues
o classi ica ion and equi emen s.
Ma e ials and me hods: li e a y sou ces o he pe iod om 2010 o 2025 we e used as
ma e ials. The s udy used he decons uc ion me hod and aspec analysis.
Resul s: Acco ding o he da a p o ided in he li e a u e, mode n pedia ic dosage o ms ha e
se e al classi ica ions. Thus, by s a e o agg ega ion, dosage o ms o child en can be di ided in o
h ee main g oups: liquid (solu ion, d ops, sy up, sp ay), solid (powde , g anules, able s, lyophilisa e)
and wi h an elas ic- iscoplas ic medium (supposi o ies, so capsules, c eam, gel). The e is also a
classi ica ion by he ou e o adminis a ion: en e al (o al, sublingual, ec al) and pa en e al
(oph halmological, in anasal, de ma ological, injec ion, in a aginal, e c.) (Sine a e al.; 2014,
Okho niko a V.F. e al., 2016; Molod so a E.A. e al., 2021).
Medicines o child en a e subjec o a numbe o equi emen s. Fo example, hey mus ha e
an a ac i e appea ance, posi i e o ganolep ic p ope ies (pleasan as e and odo ), and, ideally, be
easily and painlessly adminis e ed. Also undamen al is he d ug's e ec i eness wi h minimal side
e ec s. Special equi emen s apply o dosage o ms and ou es o adminis a ion, which di ec ly
depend on he pa ien 's age and physiological cha ac e is ics. I is no ecommended o use la ge
numbe s o excipien s when de eloping a dosage o m, especially o medica ions in ended o
in an s. In pa icula , many esea che s ag ee ha e hanol is undesi able in pedia ic medica ions. I
is impo an o ensu e he equi ed le el o mic obiological pu i y o he medica ions, and o
medica ions in ended o newbo ns, s e ili y. Sou ces also p o ide equi emen s o packaging
pedia ic medica ions: o p e en poisoning, con aine s mus be di icul o open o child en
(p o ec i e caps o ials, special bands o able s, combina ion locks o packages, e c.). (Nunn T e
al., 2005; I ano ska V. E al., 2014; Kuzne so A.V. e al., 2011; Khano a N.I., 2009; Na ke ich
I.A. e al., 2016; Sine a T.D. e al., 2019; Ego o a S.N., 2019; Telno a E.A. e al., 2020).
Conclusions: A li e a u e e iew demons a es ha pedia ic d ug de elopmen has nume ous
unique cha ac e is ics and equi es an indi idualized app oach in each case. The e o e, esea ch in
his a ea is one o he mos p essing challenges in mode n pha maceu icals.
