283
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE “MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
STORAGE REQUIREMENTS AND SHELF LIFE OF THE DIURETIC HERBAL
PREPARATION ‘ALERVA’
B. J. Khasano a
N. K. Olimo
M. U. Abdullae a
Z. E. Sidame o a
Tashken Pha maceu ical Ins i u e, Tashken ci y, Republic o Uzbekis an
e-mail: [email p o ec ed]
h ps://doi.o g/10.5281/zenodo.17334400
Rele ance. He bal p epa a ions a e medicinal p oduc s based on plan componen s such as
he bs, lowe s, oo s, and ui s. They possess a ious he apeu ic and es o a i e p ope ies and a e
o en used as p e en i e emedies. I is impo an o emembe ha p ope s o age o he bal
p epa a ions and adhe ence o hei expi a ion da es di ec ly a ec hei e ec i eness and sa e y.
The shel li e o he bal p epa a ions di ec ly depends on hei composi ion, me hod o
p epa a ion, and packaging o m. Manu ac u e s usually indica e a shel li e o 1 o 3 yea s on he
packaging o he bal p oduc s. I is impo an o ollow he ecommended s o age condi ions and
pe iods, as he bal p epa a ions may lose hei medicinal p ope ies a e he expi a ion da e.
Following s o age ecommenda ions and using he p oduc s in a imely manne ensu es he
p ese a ion o he bene icial p ope ies o he bal p epa a ions and maximizes hei heal h bene i s.
Objec i e. The aim o ou esea ch is o analyze he s o age condi ions and shel li e o he
diu e ic he bal p epa a ion “Ale a,” de eloped a he Depa men o Pha macognosy and
S anda diza ion o Medicinal P oduc s.
Ma e ials and Me hods. Expe imen s o de e mine he s o age condi ions o he il e -bag
p epa a ion “Ale a” we e conduc ed o assess quali y indica o s o he inished p oduc : appea ance,
au hen ici y, mois u e con en (%), deg ee o g inding (mm), mass o one package (g), con en o
wa e -soluble ex ac i e subs ances (%), mic obiological pu i y, and o al la onoid con en
(measu ed as u in, %) unde na u al condi ions — s o ed o 30 mon hs in a oom a 25 ± 2.0 °C and
ela i e humidi y o 60–75%. These pa ame e s we e compa ed wi h he ini ial quali y indica o s.
The he bal p epa a ion “Ale a” in il e -bag o m was packed in con aine s app o ed o
medical use. S o age o he il e -bag p epa a ion “Ale a” unde na u al condi ions was moni o ed
o e 2.5 yea s by e alua ing quali y indica o s e e y 6 mon hs and de e mining he con en o ac i e
subs ances.
Resul s. The s udy esul s showed ha he diu e ic he bal p epa a ion “Ale a,” packaged in
h ee di e en ypes o packaging ma e ials, main ained i s quali a i e and quan i a i e cha ac e is ics
h oughou he 30-mon h obse a ion pe iod. Howe e , he quali y indica o s o he he bal mix u e
packed in aluminum oil and nylon bags we e lowe han hose o he mix u e packed in il e pape
bags. The e o e, he p io i y o packaging ma e ials was as ollows: il e pape bag ˃ aluminum oil
bag ˃ nylon bag.
Conclusions. The diu e ic he bal p epa a ion “Ale a” s o ed unde na u al condi ions o 30
mon hs was e alua ed acco ding o he s udied quali y pa ame e s and echnical equi emen s. I was
es ablished ha he mos op imal packaging o “Ale a” is a il e pape bag. Addi ionally, he shel
li e o he p epa a ion unde oom empe a u e (25 ± 2.0 °C) and ela i e humidi y no exceeding 75%
was de e mined o be 2 yea s.
