327
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE “MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
LICORICE ROOT (GLYCYRRHIZA GLABRA L.) AS A MEDICINAL PLANT FROM
SOUTHERN KAZAKHSTAN
Mu zabae B.A.
Head o he Resea ch Labo a o y "Ag o-Indus ial Complex Enginee ing",
Shymken ci y, Republic o Kazakhs an
e-mail: [email p o ec ed]
h ps://doi.o g/10.5281/zenodo.17336967
Rele ance: Lico ice (Glycy hiza spp.) is a genus o pe ennial legumes whose oo s a e widely
used in adi ional medicine as an expec o an , an i-in lamma o y, and an i i al agen . In Kazakhs an,
lico ice is ound in he s eppes and along mois i e loodplains, especially in he sou he n egions
(Tu kes an, Zhambyl, and Alma y egions). In ecen yea s, he e has been in ensi e ha es ing o
wild-g owing s ocks, which pu s he species a isk in some a eas. Objec i e: To cha ac e ize he
phy ochemical p o ile o lico ice oo s collec ed in he sou he n egions o Kazakhs an and o assess
he po en ial o lico ice o he phy omelio a ion o saline soils.
Ma e ials and Me hods: Raw ma e ial collec ion. Loca ions: h ee si es in sou he n
Kazakhs an ( oughly: Region A - i e loodplain; Region B - s eppe a ea; Region C - sal ma shes
a ound oases). Time: la e au umn (be o e oo do mancy) o maximize he accumula ion o seconda y
me aboli es.
P epa a ion: oo washing, d ying a 40–45°C o cons an weigh , g inding o powde .
Ex ac ion. Sol en s: 70% me hanol (polyphenol p o ile), wa e ( adi ional), chlo o o m/e hyl
ace a e (lipophilic ac ions). Me hod: mace a ion o 24–48 hou s a oom empe a u e wi h a 1:10
a io ( aw ma e ial:sol en ), il a ion, and sol en e apo a ion unde acuum. Phy ochemical
analysis. To al phenolic ac i i y: Folin-Ceccal eu me hod (TPC), esul s exp essed as mg gallic acid
equi alen pe g o aw ma e ial (mg GAE/g).
Fla onoids: aluminum chlo ide complexa ion me hod. Field phy omelio a ion model.
Resul s: The 70% me hanol ex ac is cha ac e ized by he highes con en o phenols and
la onoids.
Glycy hizin is he main quan i ied componen (≈34 mg/g d y oo ), con i ming he
pha macological ele ance o he aw ma e ial (an i-in lamma o y, swee as e).
Phy omelio a ion. Field expe imen on saline plo s: plo s (con ol and lico ice sowing),
measu emen o soil elec ical conduc i i y (EC), soluble sal con en , and o ganic ma e be o e and
a e 2–3 seasons.
When lico ice is plan ed in sligh ly saline soils, a endency owa d dec eased o e all salini y
and inc eased o ganic ma e in he oo ing ho izon is obse ed wi hin 2–3 yea s (depending on
clima e and ini ial soil condi ions).
Li e a u e da a con i m ha Glycy hiza glab a possesses an ioxidan , an i-in lamma o y, and
an i i al ac i i y; he main di e ences be ween popula ions a e he quan i a i e a ios o me aboli es,
making local s udies impo an o he s anda diza ion o aw ma e ials.
Fo sou he n Kazakhs an, issues o sus ainable ha es ing and p o ec ion a e impo an , as
in ensi e illegal oo ha es ing has been eco ded in a numbe o a eas.
Conclusions: Lico ice oo collec ed in sou he n Kazakhs an is a p omising aw ma e ial o
he pha maceu ical and cosme ic indus ies. The conduc ed and p oposed expe imen s p o ide a
me hodological basis o assessing he quali y o he aw ma e ial, i s pha macological po en ial, and
i s en i onmen al applica ion in phy omelio a ion.
