344
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE “MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
HANDELIA TRICHOPHYLLA POLYSACCHARIDES
Sh. O. Ashi bae a¹,²
F. A. Kodi alie a²
R. K. Rakhmanbe dye a²
¹B anch o he Russian Chemical-Technological Uni e si y named a e D. I. Mendeleye ,
Tashken ci y, Republic o Uzbekis an
²S.Yu. Yunuso Ins i u e o Chemis y o Plan Subs ances., Tashken ci y, Republic o
Uzbekis an
e-mail: a imahon.82@ mail. u
h ps://doi.o g/10.5281/zenodo.17337384
Rele ance: Handelia ichophylla is a pe ennial he baceous plan o he As e aceae amily,
widesp ead in Cen al Asia. The plan con ains a ich complex o biologically ac i e subs ances:
essen ial oils, sesqui e pene lac ones, la onoids, polysaccha ides, annins, amino acids, choline,
ca o enoids, asco bic acid, o ganic acids, and suga s. S udying he ca bohyd a e complex o his
species is o in e es o he sea ch o new sou ces o na u al polysaccha ides wi h po en ial
biological ac i i y.
S udy Objec i e: Isola ion and cha ac e iza ion o he ca bohyd a e complex (alcohol-soluble
suga s, wa e -soluble polysaccha ides, pec in subs ances, and hemicelluloses) om he lowe s,
lea es, and s ems o H. ichophylla.
Ma e ials and Me hods: The s udy subjec was ai -d ied, g ound aw ma e ials ( lowe s,
lea es, and s ems) o H. ichophylla.
1. The aw ma e ials we e p e- ea ed wi h a mix u e o chlo o o m and me hanol o emo e
a y acids. 2. Ex ac ion was pe o med wi h boiling 82% e hanol; alcohol-soluble suga s (ASS),
iden i ied by biochemical analysis as uc ose and suc ose, we e isola ed. 3. Wa e -soluble
polysaccha ides (WSPS), pec in subs ances (PS), and hemicelluloses (HMC) we e isola ed om he
esidue. 4. Monosaccha ide composi ion was de e mined by HPLC (Table 1).
Table 1. Con en and monosaccha ide composi ion o polysaccha ides
Type PS
Yield,
%
Monosaccha ide Composi ion, HPLC in %
UAc,
PC
Rha
A a
Xyl
Glc
Gal
Flowe s
WSPS
3.76
-
61.9
19.78
12.1
6.2
+
PS
2.32
30.2
7.69
31.2
24.1
6.7
+
HMS
1.24
54.7
51.6
31.6
2.61
5.4
+
Lea es
WSPS
5.0
10.1
47.8
15.5
9.26
17.2
+
PS
7.0
-
44.87
27.96
15.16
12.0
+
HMS
9.8
61.07
30.3
-
6.35
2.27
+
S ems
WSPS
0.6
49.75
35.85
-
7.46
6.93
+
PS
2.2
-
40.32
33.31
15.09
11.26
+
HMS
7.4
86.5
10.9
-
0.58
1.98
+
345
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE “MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
The highes con en o WPPS, PV, and HMC was ound in H. ichophylla lea es. All isola ed
polysaccha ides we e acidic in na u e; neu al suga s we e p esen in a ying p opo ions, bu xylose
was he dominan monosaccha ide. F uc ose and suc ose we e de ec ed in he alcohol-soluble
ac ion.
