378
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE “MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
PHENOLIC COMPOUNDS OF PLANTS BELONGING TO THE GENUS
ATRAPHAХIS
Yulchiye a U.A.
Abdullaye Sh.V.
N.G’. Abdulladjono a
Namangan S a e Uni e si y; Ins i u e o Bioo ganic Chemis y
Academy o Sciences o he Republic o Uzbekis an
h ps://doi.o g/10.5281/zenodo.17339131
A p esen , he isola ion o biologically ac i e subs ances om plan s, he comp ehensi e s udy
o hei chemical s uc u e and p ope ies, as well as he in es iga ion o hei biological and
pha macological cha ac e is ics, is one o he u gen asks. Phenolic compounds, which a e
widesp ead in he plan kingdom, ep esen a la ge class o na u al compounds. Phenolic compounds
pa icipa e in a ious p ocesses occu ing in he human body and exhibi an ioxidan p ope ies;
mo eo e , as an i adical agen s, hey slow down adical mechanism-based eac ions ha ake place
in he o ganism unde he in luence o ex e nal physico-chemical ac o s. I has been es ablished ha
phenolic compounds in he human body enhance immuni y agains diseases caused by bac e ia and
i uses and possess he apeu ic p ope ies. In pa icula , ca bohyd a es, mac o- and mic oelemen s,
i amins, hyd olyzable annins, la onoids, o ganic acids, and o he classes o compounds ha e been
isola ed om plan s o he genus A aphaxis belonging o he amily Polygonaceae, and on hei
basis, medicinal p epa a ions wi h e ec i e biological ac i i y a e widely used in medical p ac ice.
Species o he genus A aphaxis a e mainly highly b anched sh ubs and subsh ubs ha g ow in a id
zones o empe a e s eppe and dese egions o Cen al Asia, Ame ica, and Aus alia. Below, we will
discuss he medicinal p ope ies o ce ain plan s belonging o his amily:
A aphaxis u escens- (I an, Kazakhs an, Uzbekis an) — in alle ia ing s omach and diges i e
diso de s;
A aphaxis py i olia- (I an, Kazakhs an, Uzbekis an) — in he ea men o diseases, as hma,
cough, a ious wounds, and skin in lamma ions;
A aphaxis b inaludensis- (I an, Kazakhs an) — in educing in lamma ion in a h i is, in he
ea men o join pain, and in skin in lamma ions;
A aphaxis spinosa- (Alge ia, Uzbekis an) — in ea ing s omach- ela ed diso de s and
diseases a ec ing in es inal heal h;
A aphaxis se a schanica- (Tu kmenis an, Tajikis an) — ound o be used in wound healing
and in he ea men o skin in lamma ions.
Fo he i s ime, he chemical composi ion o he ae ial pa s o A aphaxis py i olia, a species
o he genus A aphaxis g owing in he Tashken egion, has been s udied.
In he s udy o he polyphenols in i s composi ion, he ae ial pa s o he plan we e i s
collec ed and d ied in a cool place. Two hund ed g ams o he plan ma e ial we e weighed, and h ee
successi e ex ac ions we e ca ied ou a oom empe a u e o 24 hou s each wi h 70% ace one a a
1:5 a io. The ace one ex ac s we e il e ed and concen a ed using a o a y e apo a o a 50 °C. The
concen a ed ex ac was ac iona ed wi h e hyl ace a e. The e hyl ace a e ac ion ob ained was
e apo a ed using a o a y e apo a o a 30 °C. The esul ing concen a e was p ecipi a ed wi h
chlo o o m.
Fla onoids
A aphaxis py i olia
379
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE “MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
Concen a ion (mg/g)
Dihyd oque ce in
10.63
Ru in
28.71
Que ce in
3.84
Salid oside
5.94
Roza in
21.61
When he o al polyphenolic composi ion was analyzed using High-Pe o mance Liquid
Ch oma og aphy (HPLC) wi h s anda d compounds, i was es ablished ha he ae ial pa s o
A aphaxis py i olia con ain he polyphenols u in, dihyd oque ce in, que ce in, salid oside, and
osa in. The HPLC esul s indica e ha he su icien p esence o he la onoids u in, osa in, and
dihyd oque ce in in A aphaxis py i olia e eals p omising p ospec s o he de elopmen o
pha maceu icals and biologically ac i e supplemen s (BAS) based on his plan .
