381
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE “MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
SYNTHESIS OF ENTEROADSORBENT-INTRODUCING Fe AND Al
POLYHYDROXYCATION BETWEEN MONTMORILLONITE LAYERS
Ju aye a F.N.
Alikulo a H.A.
Bol aye a G.X.
Tashken Pha maceu ical Ins i u e, Tashken ci y, Republic o Uzbekis an
e-mail: [email p o ec ed], phone: (93) 560-34-89
h ps://doi.o g/10.5281/zenodo.17339179
E iciency: en e oso ben s a e subs ances wi h a high speci ic su ace a ea, capable o adso bing
molecules, ions and a ious pa icles. They a e used in medicine o a ious pu poses, hey ha e
an imic obial and de oxi ying p ope ies, o example, he abili y o bind o hea y me als and oxins,
and hey a e used in he pe o mance o some complex asks, such as poisoning models ( ood
poisoning, dia hea, alle gies). The e o e, he syn hesis o adso ben s and ca alys ca ie s, which a e
absolu ely ha mless o human heal h and economically inexpensi e, wi h high adso p ion p ope ies,
is conside ed u gen oday.
The pu pose o he esea ch: o de elop me hods o op imal en ichmen o na u al clay mine als
o he c ea ion o en e oadso ben s and o de e mine he composi ion o en iched samples.
Me hods and echniques: K an au mine ben oni e (KP) and Na baho alkaline ben oni e (NIB),
which a e widesp ead in ou coun y, we e selec ed as he objec o he esea ch. En ichmen o he
selec ed esea ch objec s wi h espec o mon mo illoni e, he main mine al wi h high adso p ion
p ope ies, was ca ied ou as ollows: he sample was mixed in dis illed wa e (pH=6.6) and wa e in
a mass a io o 1:10 o o m a suspension o 100 g. In o de o con e he calcium ben oni e con ained
in he suspension in o i s sodium o m and p ecipi a e Ca2+ and o he Me2+ ions, Na2CO3 was added
in he amoun o 0.5% o he solid sample mass, he suspension was s i ed in a magne ic s i e o
15 minu es and allowed o s and o 48 hou s. Then he suspension was dilu ed wi h wa e in a a io
o 1:5 while s i ing. In his p ocess, Ca2+, Fe2+, Fe3+ sal s, qua z and o he wa e -insoluble subs ances
wi h high dispe sibili y a e sepa a ed in o he sedimen . Du ing he i s 20 minu es, he uppe pa o
he suspension was sepa a ed om he pa ha had se led by decan a ion. The esul ing suspension
was sepa a ed om he solid phase by cen i uga ion. The ion indica o s o each s age we e
de e mined on he IM-160 de ice, he ob ained esul s a e p esen ed in Figu e 1. In o ma ion abou
he s uc u e o en iched clay mine als can be de e mined by he mal analysis. Simul aneous dynamic
he mog a ime ic and calo ime ic analyzes we e ob ained using a Se a am Labsys e o appa a us.
Figu e 1
Resul : As a esul o changes in suspension pH
alues du ing he en ichmen p ocesses, i can be
seen ha he pH indica o s dec ease om 8.74 o
7.22 and om 8.68 o 7.95 in KP and NIB samples,
espec i ely. Acco ding o he esul s o synch onous
dynamic he mog a ime ic calo ime ic analyses:
(A- KP and B- NIB) he mog a ime ic analysis
cu e (DTGA cu es show ha in ense
decomposi ion ook place in KP ben oni e be ween
empe a u es o 55-157℃ and 166-457℃. In NIB,
decomposi ion empe a u es co espond o he ange
382
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE “MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
o 63-148℃ and 159-417℃. The ini ial decomposi ion The amoun o mass loss a empe a u es
(100-150℃) p o es ha na u al clay mine als a e ich in sodium mon mo illoni e.
Conclusion: Based on he analysis o he ob ained esul s, i can be concluded ha he change
in pH alues means ha na u al ben oni es a e en iched wi h he main impo an mine al
mon mo illoni e due o he dec ease in he amoun o addi ional subs ances. he en ichmen me hod
used inc eases he amoun o mon mo illoni e in he na u al clay mine als and inc eases hei
adso p ion and o he colloidal-chemical p ope ies.
