Coleção Documen os
2030 Sus ainable
De elopmen Goals
UMinho Resea ch & Inno a ion Open Days
30-31 Janua y 2024, B aga, Po ugal
COORDENAÇÃO EDITORIAL
Manuela Ma ins
CAPA
UMinho Edi o a
DESIGN e PAGINAÇÃO de:
"2030 Sus ainable De elopmen Goals - UMinho Resea ch and Inno a ion Open Days”
CAPA Nicolau Mo ei a
PAGINAÇÃO Tiago Fa inha
EDIÇÃO UMinho Edi o a
LOCAL DE EDIÇÃO B aga 2025
ISBN DIGITAL 978-989-9074-65-1
DOI h ps://doi.o g/10.21814/uminho.ed.195
Os con eúdos ap esen ados ( ex os e imagens) são da exclusi a esponsabilidade dos espe i os au o es.
© Au o es / Uni e sidade do Minho – Es a ob a encon a-se sob a Licença In e nacional C ea i e Commons A ibuição 4.0.
EDITORES
Eugénio Campos Fe ei a
Sand a Pai a
COMITÉ ORGANIZADOR
Eugénio Campos Fe ei a
Sand a Pai a
Te esa Ruão
Cecília Leão
An ónio Vicen e
COLABORAÇÃO TÉCNICA
Tiago Fa inha
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
1
BOOK OF ABSTRACTS OF THE
UMINHO RESEARCH & INNOVATION OPEN DAYS
ADDRESSING THE 2030 SUSTAINABLE DEVELOPMENT GOALS
30-31 JANUARY 2024, BRAGA, PORTUGAL
This olume con ains he abs ac s o he pos e and o al communica ions p esen ed a he UMinho
Resea ch & Inno a ion Open Days, held in B aga, Po ugal, be ween Janua y 30 h and 31s , 2024.
h ps://www.uminho.p /PT/siga-a-uminho/Paginas/De alhe-do-e en o.aspx?Codigo=63074
Edi ed by Eugénio Campos Fe ei a and Sand a Pai a
ORGANIZING COMMITTEE
Eugénio Campos Fe ei a
Sand a Pai a
Te esa Ruão
Cecília Leão
An ónio Vicen e
TECHNICAL COLLABORATION
Tiago Fa inha
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
2
CONTENTS
CONTENTS ......................................................................................................................................... 2
SUSTAINABLE DEVELOPMENT GOALS INDEX .............................................................................................. 5
FOREWARD ........................................................................................................................................ 6
CENTRO ALGORITMI .......................................................................................................................... 7
Sus ainable Incen i es o P ocess Tokenisa ion in he Public Sec o .................................................................................... 8
Pho o ol aic Elec i ica ion o O -G id in Schools and Heal h Uni s in Angola ..................................................................... 9
CENTRO DE BIOLOGIA MOLECULAR E AMBIENTAL ..................................................................................... 10
Biop ospec ion o Ma ine Mic oo ganisms as a Sou ce o Inspi a ion o Design No el An imic obial Pep ides ................. 11
Candida Albicans Ace a e T anspo e O hologues (A os): Docking and Exp ession S udies ............................................. 12
E ec s o Cellulose Powe -Plan Was ewa e on Ben hic Assemblages .............................................................................. 13
Gene a ion o Molecula Tools o Analyse he Exp ession o Mammalian Monoca boxyla e T anspo e s ....................... 14
ZnO-Based Thin Films as High-E iciency An i ungal Coa ings ............................................................................................. 15
T ansc ip omic Analysis o C. Albicans Cells in Dis inc Me abolic Condi ions .................................................................... 16
Fungi and Nu i ion: Exp ession and Subcellula Localiza ion Pa e ns o A o2 T anspo P o ein o Candida Albicans .... 17
Decoding Alkali S ess Responses in Fungi ........................................................................................................................... 18
Analyzing he Role o Key Amino Acid Residues in Aspe gillus nige DCT-02 on Dica boxyla e T anspo .......................... 19
Explo ing Benzo[A]Phenoxazine De i a i es as An i ungal Agen s Agains Candida ........................................................... 20
G een Syn hesis o Pho oca aly ic Nanopa icles o he Elimina ion o Eme ging Con aminan s in Wa e ....................... 21
CENTRO DE CIÊNCIA E TECNOLOGIA TÊXTIL .............................................................................................. 22
Mul i unc ional Fib ous S uc u es o Ad anced Pe sonal P o ec i e Equipmen Based on Na u al Fib es and
Nanoma e ials ...................................................................................................................................................................... 23
Local D ug Deli e y Sys ems Based on Biodeg adable Nano ibe s o Cance Pho odynamic The apy (PDT) ..................... 24
Elec ic P ope ies o Co on Fab ics P epa ed wi h Py og a ® III Ca bon Nano ibe -Based Aqueous Inks ......................... 25
Sus ainable and Func ional Fashion Design: A Na u al Dyes App oach ............................................................................... 26
Design in he Feminine: Knowledge, Tex ile and Fashion Design ........................................................................................ 27
S a egies o Enhance Ecological Colo a ion in Fashion Design: Sus ainable Colo ............................................................. 28
Sma P in ed Tex ile Design and he C ea ion o Symbolic Value Th ough Emo ional Expe ience .................................... 29
Educa ion o Ci cula Economy: Con ibu ions o he De elopmen o Inno a i e Teaching-Lea ning Me hodologies and
S a egies ............................................................................................................................................................................. 30
CENTRO DE ENGENHARIA BIOLÓGICA ..................................................................................................... 31
Mic obial lipids p oduc ion by Ya owia lipoly ica s ains om lignocellulosic biomass hyd olysa es ............................... 32
Explo ing Ya owia Lipoly ica s ains o biocon e sion o hyd oca bons in o high- alue compounds .............................. 33
Valo iza ion o Red, G een and B own Seaweeds Th ough Solid-S a e Fe men a ion o Imp o e i s Nu i ional Value .... 34
The Hidden Po en ial o Hype saline En i onmen s: Ex emophiles as Sou ce o New Biosu ac an s .............................. 35
Assessmen o he Po en ial o Na u al Mic obiomes o Mic oplas ics Biodeg ada ion: A Compa a i e S udy o Poly(ε-
cap olac one), Polye hylene and Polye hylene Te eph hala e ............................................................................................ 36
De elopmen o Foam-F ee Biosu ac an P oduc ion P ocesses Using Bacillus licheni o mis S ains ............................... 37
Unco e ing no el Ca bohyd a e-Deg ading Enzymes om Compos ing Uni s Th ough Me agenomic S a egies ............. 38
Inno a i e In eg a ion o Oil ield P oduced Wa e T ea men wi h Biogas P oduc ion o Sus ainable Resou ce
Managemen ........................................................................................................................................................................ 39
Cobal and Manganese Specia ion in Anae obic Sludge T ea ing PTA P oduc ion Was ewa e ......................................... 40
CENTRO DE FÍSICA DA UNIVERSIDADE DO MINHO E DO PORTO .................................................................... 41
Passi e Sampling o Ai Quali y Assessmen : Collabo a ion Be ween CCDR-N and Uni e si y o Minho ........................... 42
De elopmen o Co e-Shea h Phase Change Fib es Inco po a ed wi h PEG2000 o The mo egula ion Applica ion ......... 43
Unde s anding he In luence o Mechano-Elec ical S imuli o New Neu onal Regene a ion The apies .......................... 44
S a egy o Sa egua d Co k and Rubbe Applica ion’s Beau y and Longe i y: Sus ainable Thin Film Deposi ion ............... 45
Neu o ansmi e De ec ion wi h G aphene Nanobiosenso s ............................................................................................. 46
Sus ainable Ma e ials o An i-Coun e ei ing Applica ions ................................................................................................. 47
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
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Eco-F iendly Li hium-Ion Ba e y Sepa a o s based on Ca ageenan Biopolyme o Sus ainable Ene gy S o age Sys ems
............................................................................................................................................................................................. 48
Localized Su ace Plasmon Resonance (LSPR) Senso s Based on Spu e ed Nanoplasmonic Thin Films ............................. 49
3D-P in ed Mul ilaye Memb anes o Pho oca aly ic Deg ada ion o Cip o loxacin .......................................................... 50
A omola Sensing o Mu a ed B ain Tumo DNA Using Elec oly e-Ga e G aphene T ansis o s ....................................... 51
In es iga ing Fluo ina ed Polyme Ma ices' Impac on Solid Polyme Elec oly e Pe o mance wi h Ionic Liquids o
Ad anced Solid-s a e Li hium-Ion Ba e ies ......................................................................................................................... 52
CENTRO DE INVESTIGAÇÃO EM ENFERMAGEM .......................................................................................... 53
Cos - E ec i eness o a Heal h P omo ion P og am in P ima y Schools and Child en in Socially Vulne able Condi ions -
clus e - andomized s udy (BeE-school) ............................................................................................................................... 54
CENTRO DE INVESTIGAÇÃO EM JUSTIÇA E GOVERNAÇÃO ............................................................................ 56
The Legal Regime o En i onmen al O enses in Po ugal - An Analysis Aimed a P omo ing The 2030 Sus ainable
De elopmen Goals .............................................................................................................................................................. 57
A i icial In elligence in Heal hca e: De ying he Legal Pa adigm ........................................................................................ 58
The igh o a Jus T ansi ion in Eu opean Union Law: S udies on he Ene gy Taxa ion Di ec i e ....................................... 59
Analysis o he In e ac ion Be ween Law and E hics in Regula ing A i icial In elligence Amid Digi al Me amo phosis ..... 60
CENTRO DE INVESTIGAÇÃO EM PSICOLOGIA ............................................................................................. 61
E ec i eness o he Sho Mo i a ional P og amme: A Randomized Con ol T ial ............................................................. 62
Empa hy and Execu i e Func ioning in Inca ce a ed Women: Compa a i e Analysis Be ween Violen and Non-Violen
C imes .................................................................................................................................................................................. 63
“A Rainbow School P og am”: De elopmen and Assessmen o an In e en ion wi h Educa ional Agen s o P e en
Vic imiza ion o LGBTQ S uden s ......................................................................................................................................... 64
De elopmen and E ec i eness Assessmen o an In e en ion o In e ne Child Sex O ende s Using a Randomized
Con ol T ial .......................................................................................................................................................................... 65
Da k T iad, Sex ing, and Online G ooming: Male olen Side o Online Sexual Ac i i y in Young Adul s ............................. 66
Social In eg a ion Skills Du ing Imp isonmen : A Longi udinal S udy .................................................................................. 67
Online G ooming o Child en: P e alence and Impac ......................................................................................................... 68
Emo ional P ocessing in Male P isone s: Compa ing Psychopa hs and Non-Psychopa hs .................................................. 69
Execu i e Func ioning and Empa hy in Male Inma es: A Compa ison Be ween Violen and Non-Violen C imes .............. 70
CENTRO DE QUÍMICA ......................................................................................................................... 71
Compu a ional Elucida ion o he Inhibi ion o Myoglobin Agg ega ion by Polye hylene glycol ........................................ 72
Eugenol as Building Block o Po en ial Insec icides .............................................................................................................. 73
De elopmen o na u al polyme -based memb anes o en i onmen al emedia ion ....................................................... 74
CENTRO DE SISTEMAS MICROELETROMECÂNICOS ..................................................................................... 75
Shape Memo y Alloy A i icial Muscles – Cu en S a e o Resea ch and Design P oposal ................................................. 76
On-Chip Op ical Mic osys em o Plasmodium Falcipa um Mala ia De ec ion ................................................................... 77
Fall Risk Assessmen in Olde Adul s: Towa ds Real-Time & Con inuous Es ima ion .......................................................... 78
INSTITUTO DE CIÊNCIAS DA TERRA ......................................................................................................... 79
De eloping a 3D Web-GIS Mapping Pla o m o Suppo Seismic Vulne abili y Assessmen o U ban A eas: An
In oduc ion ......................................................................................................................................................................... 80
INSTITUTO DE INVESTIGAÇÃO EM CIÊNCIAS DA VIDA E DA SAÚDE ................................................................. 81
Spa io empo al P o iling o Gene Exp ession Du ing Sa coid G anuloma Fo ma ion .......................................................... 82
Gene ic Va ia ion In Il-37 In luences he Immune Response To Aspe gillus Fumiga us And P edisposes To Fungal Disease
A e S em-Cell T ansplan a ion ........................................................................................................................................... 83
Enhancing Mala ia Elimina ion S a egies in he Dominican Republic: E alua ing Rapid Diagnos ic Tes Accu acy and
Un a eling Pa asi e Gene ic Di e si y .................................................................................................................................. 84
No ad ene gic Degene a ion in a DJ-1 Knockou Mouse Model ......................................................................................... 85
I acona e De iciency Enhances An i-Fungal E ec o Func ions o Mac ophages and Con e s Resis ance o In ec ion wi h
Aspe gillus umiga us ........................................................................................................................................................... 86
Expansion o Induced Plu ipo en S em Cell-De i ed Mesenchymal S em Cells Using a Xenogeneic-F ee Human Pla ele
Lysa e as G ow h Medium Supplemen ............................................................................................................................... 87
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
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Omega-Sec: P iming Adipose-Tissue Mesenchymal S em Cells Sec e ome wi h Docosahexaenoic-Acid o Regene a i e
Medicine Applica ions in he Cen al Ne ous Sys em ........................................................................................................ 88
INSTITUTO DE POLÍMEROS E COMPÓSITOS .............................................................................................. 89
S udy o he P ocessing and P ope ies o Ni ile Rubbe (NBR) wi h Residues om Flexible Polyu e hane (PU) Foams ... 90
Composi e Fibe s wi h High Lignin Con en as P ecu so s o Ca bon Fibe s ...................................................................... 91
Use o Ci cula i y Mic o-Le el Indica o s in he De eloping P ocess o Plas ic Pa s o he Au omo i e Indus y ............ 92
Magne ically T igge ed Shape De o ma ion o Polyu e hane Composi es .......................................................................... 93
S udy o o ganolep ic addi i es and insec epellen s o Pos -consume ecycled polyole ins .......................................... 94
De elopmen o Eco-Sus ainable Composi e Sandwich S uc u al Panels ........................................................................... 95
Calcula ing he Ca bon Foo p in o Plas ic Pa s ................................................................................................................ 96
P ocessing and Cha ac e iza ion o Pos -Consume Recycled Ma e ials o Ro a ional Moulding Applica ions ................. 97
S udies on he Rep ocessing o Polye hylene and Polyp opylene Blends ............................................................................ 98
Ci cula i y h ough Recycling o The moplas ic Ma ix Composi es .................................................................................... 99
INSTITUTO PARA A SUSTENTABILIDADE E INOVAÇÃO EM ESTRUTURAS DE ENGENHARIA ................................... 100
Adap a ion o T adi ional Risk-Based Me hodology o Slopes o P obabilis ic-Based App oach In eg a ing Su oga e
Models ............................................................................................................................................................................... 101
De elopmen o an Ecological The mal Insula ion P oduc o a Regene a i e Building Design ....................................... 102
S a egies and ac ions o achie ing ca bon neu ali y in Po uguese esiden ial buildings by 2050 ................................ 103
Analyzing he Feasibili y o In eg a ing U ban Sus ainabili y Assessmen Indica o s wi h Ci y In o ma ion Modelling (CIM)
........................................................................................................................................................................................... 104
De elopmen o Op imised Comp essed Ea h Blocks by Using Ma e ials o Na u al O igin ............................................ 105
Ad ancing Sus ainable In as uc u e Assessmen : G ound Pene a ing Rada (GPR) o Non-Des uc i e E alua ion o
Asphal Pa emen s ............................................................................................................................................................. 106
LABORATÓRIO DE INSTRUMENTAÇÃO E FÍSICA EXPERIMENTAL DE PARTÍCULAS .............................................. 107
Applica ion o Quan um Compu ing o Quan um Ch omodynamics ................................................................................. 108
Anomaly De ec ion: A Tool o Find New Physics ................................................................................................................ 109
Using Machine Lea ning and A i icial In elligence o Scan Beyond he S anda d Model Pa ame e Spaces in Pa icle
Physics ................................................................................................................................................................................ 110
LABORATÓRIO DE PAISAGENS, PATRIMÓNIO E TERRITÓRIO ....................................................................... 111
Anad omous Seascapes: Unde s anding Ma ine Spa ial Usage in Tackling he Impac o U ban In as uc u e on
Mig a o y Species. .............................................................................................................................................................. 112
Au ism and Highe Educa ion: A Look a Design ................................................................................................................ 113
LABORATÓRIO DE SOFTWARE CONFIÁVEL .............................................................................................. 114
How Sus ainable is you P og amming Language? Analysing he Impac o Powe Cap on Ene gy E iciency o
P og amming Languages .................................................................................................................................................... 115
NÚCLEO DE INVESTIGAÇÃO EM POLÍTICAS ECONÓMICAS .......................................................................... 116
The P omo ion o Sus ainabili y in Highe Educa ion Ins i u ions: Key Fac o s o Adop om he O ganiza ional
Pe spec i e ......................................................................................................................................................................... 117
Full-Time Educa ion: Assessmen o The Impac on Lea ning o he B azilian P og am No o Mais Educação .................. 118
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
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SUSTAINABLE DEVELOPMENT GOALS INDEX
SDG1 .................................................................................................................................................................... 59, 77, 80
SDG2 .............................................................................................................................................................. 18, 34, 49, 73
SDG3 9, 11, 12, 14, 15, 16, 17, 20, 23, 24, 36, 42, 44, 46, 49, 51, 54, 58, 62, 64, 66, 68, 72, 76, 77, 78, 82, 83, 84, 85, 86,
88
SDG4 8 ........................................................................................... , 9, 28, 54, 64, 65, 68, 77, 108, 109, 110, 113, 117, 118
SDG5 ........................................................................................................................................................ 18, 27, 47, 62, 63
SDG6 ....................................................................................................................................... 21, 28, 36, 37, 39, 40, 50, 74
SDG7 ............................................................................................................... 9, 21, 25, 32, 33, 39, 48, 50, 52, 59, 74, 103
SDG8 ................................................................................................................. 8, 27, 28, 29, 60, 88, 91, 98, 108, 109, 110
SDG9 ............................................ 29, 37, 38, 43, 47, 57, 60, 80, 82, 83, 86, 87, 92, 93, 95, 96, 98, 99, 106, 109, 110, 115
SDG10 ............................................................................................................................... 27, 54, 58, 60, 82, 83, 84, 86, 113
SDG11 ............................................................................................. 15, 42, 43, 47, 57, 80, 84, 102, 104, 105, 106, 112, 117
SDG12 ...... 8, 19, 21, 23, 24, 26, 29, 30, 33, 34, 35, 37, 38, 40, 43, 48, 49, 50, 57, 73, 74, 87, 90, 92, 94, 95, 96, 97, 98, 99,
115, 117
SDG13 ................................................................ 25, 26, 30, 32, 33, 35, 37, 42, 48, 52, 59, 73, 92, 96, 98, 99, 102, 103, 105
SDG14 ............................................................................................................................................................ 13, 34, 36, 112
SDG15 ................................................................................................................................................. 8, 73, 91, 92, 102, 106
SDG16 ................................................................................................................................... 8, 58, 60, 64, 65, 66, 68, 69, 70
SDG17 ....................................................................................................................... 8, 25, 35, 42, 91, 92, 98, 103, 108, 115
SDG1 End po e y in all i s o ms e e ywhe e.
SDG2 End hunge , achie e ood secu i y and imp o ed nu i ion, and p omo e sus ainable ag icul u e.
SDG3 Ensu e heal hy li es and p omo e well-being o all a all ages.
SDG4 Ensu e inclusi e and equi able quali y educa ion and p omo e li elong lea ning oppo uni ies o all.
SDG5 Achie e gende equali y and empowe all women and gi ls.
SDG6 Ensu e a ailabili y and sus ainable managemen o wa e and sani a ion o all.
SDG7 Ensu e access o a o dable, eliable, sus ainable, and mode n ene gy o all.
SDG8 P omo e sus ained, inclusi e, and sus ainable economic g ow h, ull and p oduc i e employmen and decen wo k
o all.
SDG9 Build esilien in as uc u e, p omo e inclusi e and sus ainable indus ializa ion and os e inno a ion.
SDG10 Reduce inequali y wi hin and among coun ies.
SDG11 Make ci ies and human se lemen s inclusi e, sa e, esilien , and sus ainable.
SDG12 Ensu e sus ainable consump ion and p oduc ion pa e ns.
SDG13 Take u gen ac ion o comba clima e change and i s impac s.
SDG14 Conse e and sus ainably use he oceans, seas, and ma ine esou ces o sus ainable de elopmen .
SDG15 P o ec , es o e and p omo e sus ainable use o e es ial ecosys ems, sus ainably manage o es s, comba
dese i ica ion, and hal and e e se land deg ada ion and hal biodi e si y loss.
SDG16 P omo e peace ul and inclusi e socie ies o sus ainable de elopmen , p o ide access o jus ice o all and build
e ec i e, accoun able, and inclusi e ins i u ions a all le els.
SDG17 S eng hen he means o implemen a ion and e i alize he Global Pa ne ship o Sus ainable De elopmen .
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
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FOREWORD
I am honou ed o p esen he Book o Abs ac s o he 1s edi ion o he UMinho Resea ch &
Inno a ion Open Days, held on he 30 h and 31s o Janua y 2024. This e en ma ks a signi ican
miles one in ou sha ed jou ney o os e esea ch excellence, inno a ion, and impac ul collabo a ions
wi hin and beyond he Uni e si y o Minho.
The Open Days se e as a unique pla o m o celeb a e he achie emen s o ou esea ch communi y,
highligh he b ead h o expe ise ac oss di e se scien i ic domains, and p omo e a cul u e o
in e disciplina y and in e na ional coope a ion. This inaugu al edi ion aligns wi h UMinho's mission o
ad ance knowledge and inno a ion in esponse o socie al challenges and global p io i ies, pa icula ly
he Sus ainable De elopmen Goals (SDGs) o 2030.
The hema ic sessions, encompassing UMinho Resea ch Highligh s, Inno a ion Ecosys em, and
In e na ional Coope a ion, ha e o e ed pa icipan s a b oad spec um o insigh s. They e lec ou
commi men o add essing global challenges h ough esea ch, wi h an emphasis on open science,
e hical esea ch p ac ices, and impac ul dissemina ion. The ole o UMinho in he Po uguese
Roadmap o Resea ch In as uc u es and i s collabo a ions wi h ins i u ions like he Uni e si y o São
Paulo u he unde sco es ou leade ship in os e ing knowledge ne wo ks.
This Book o Abs ac s compiles he esea ch con ibu ions p esen ed by ou PhD s uden s mos ly in
pos e o ma du ing he wo-day e en . These abs ac s, o ganized by esea ch uni s, ep esen he
cu ing-edge wo k ca ied ou by ou academic communi y and collabo a o s. A selec ion o pos e s
was showcased du ing wo dedica ed pi ch sessions, whe e s uden s sha ed inno a i e solu ions
a ge ing he SDGs.
The abs ac s illus a e a wide ange o opics, om bio echnology and sus ainable ene gy solu ions o
legal and psychological s udies, e lec ing he di e si y and s eng h o ou esea ch ecosys em.
O ganized ac oss UMinho's esea ch uni s, hey o e a clea o e iew o he in e disciplina y and
impac ul p ojec s ha de ine ou ins i u ion.
On behal o he o ganizing commi ee, I would like o ex end my deepes g a i ude o all pa icipan s,
esea che s, and s akeholde s who ha e con ibu ed o he success o his e en . I also acknowledge
he c i ical suppo p o ided by ou inno a ion ecosys em pa ne s, associa e labo a o ies, and
in e na ional collabo a o s.
We hope his compila ion se es as a aluable esou ce o os e ing u u e collabo a ions and
ad ancing sha ed goals in esea ch and inno a ion. May i inspi e con inued explo a ion and
commi men o excellence in add essing he challenges o ou ime.
Eugénio Campos Fe ei a
Vice-Rec o o Resea ch & Inno a ion
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
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EFFECTS OF CELLULOSE POWER-PLANT WASTEWATER ON BENTHIC
ASSEMBLAGES
Da i Mundim, Diego Flo es, Ped o Gomes, Ma cos Rubal
CBMA - Cen e o En i onmen al and Molecula Biology
mundimda [email protected]; diego.ca ei a. lo [email protected]; pago[email p o ec ed]minho.p ;
m ubalg@ho mail.com
Keywo ds: Bioindica o s, O ganic En ichmen , Mac oben hos
2030 Sus ainable De elopmen Goals: SDG14
Ben hic ma ine auna plays an impo an ole in se e al ecosys em p ocesses such as he
mine aliza ion and cycling o nu ien s, he anspo o o ganic ma e and oxygen h ough
di e en laye s o sedimen , among o he s. Ben hic assemblages a e also highly sensi i e o
en i onmen al condi ions so i s a ia ions a e p obably he bes a ailable bioindica o s o
assess an h opic impac s on ma ine ecosys ems. Eu ope go e nmen s adop ed legal and
adminis a i e amewo ks such as MSFD and WFD, es ablishing ben hic auna moni o ing as
a me hod o assessing ecosys em heal h. Howe e , in he Po uguese coas hese
assemblages ha e been li le s udied, especially in he no h egion. The e o e, his wo k aims
o assess he impac s o a cellulose powe -plan e luen , loca ed in Viana do Cas elo, in he
subli o al ben hic communi ies.
The main hypo hesis is ha a eas nea he e luen will p esen an impo e ished ben hic
assemblage and as dis ance om he e luen inc eases he ben hic assemblage will p esen
a highe species numbe and lowe abundances. Ben hic assemblages and sedimen samples
we e collec ed in di e en si es wi h inc easing dis ances om he e luen o compa e di e si y,
abundance and biomass. Concluding his wo k can lead o be e unde s a ing o ganic
en ichmen e ec s on ben hic assemblages and he p oposi ion o be e ma ine managemen
amewo ks.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
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GENERATION OF MOLECULAR TOOLS TO ANALYSE THE EXPRESSION OF
MAMMALIAN MONOCARBOXYLATE TRANSPORTERS
Cla a A an es1, Cláudia Ba a a-An unes1, Diogo Lopes1, Rosana Al es1, Pie e
A A de Beule2, Ta iana So kina3, Alexande So kin3, Sand a Pai a1
1 CBMA, Depa men o Biology, Uni e si y o Minho, 4710-057, B aga, Po ugal
2 In e na ional Ibe ian Nano echnology Labo a o y, A enida Mes e José Veiga s/n, B aga,
Po ugal
3 Depa men o Cell Biology, Uni e si y o Pi sbu gh School o Medicine, Pi sbu gh, PA,
USA
[email p o ec ed]; claudia.ba a [email p o ec ed]; [email p o ec ed]!
Keywo ds: Mammalian monoca boxyla e anspo e s, Molecula ools, Plasmids
2030 Sus ainable De elopmen Goals: SDG3
Monoca boxyla e anspo e s (MCTs) a e a amily o anspo e s ha a e essen ial o he
impo o monoca boxyla es such as lac a e, playing an impo an ole in mammalian
me abolism. This amily con ains 14 iso o ms ha di e s in e ms o issue dis ibu ion,
in acellula localiza ion and egula ion o exp ession, supplying he me abolic need o he
espec i e issue in which hey a e exp essed. Gi en hei impo ance, changes in hei
exp ession, ac i i y o unc ion can lead o a numbe o clinical mani es a ions anging om
mild diso de s o se e e diseases, such as cance . The expo o lac a e om highly glycoly ic
umo cells ensu es he p og ession o glycolysis and p e en s in acellula acidi ica ion. We
hypo hesize ha he down egula ion o MCTs in speci ic cellula en i onmen s migh p o ec
om ce ain ypes o cance . To es his, se e al plasmids a e being cons uc ed, ha bo ing
MCT1 o MCT4 used wi h luo escen p o eins, mChe y o GFP, a ei he he N o C e mini.
These cons uc ions will be u he ans ec ed in speci ic human cell lines in o de o analyze
he a icking and exp ession o MCTs a ele an me abolic g ow h condi ions as well as a e
ea men wi h ce ain compounds. A he end o his wo k, we expec o cha ac e ize he
condi ions and mechanisms behind he endocy ic a icking o MCTs.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
15
ZNO-BASED THIN FILMS AS HIGH-EFFICIENCY ANTIFUNGAL COATINGS
Pa ícia Pe ei a-Sil a1, 2, Joel Bo ges2, 3, Paula Sampaio1
1 CBMA, Depa men o Biology, Uni e si y o Minho, 4710-057 B aga, Po ugal
2 Physics Cen e o Minho and Po o Uni e si ies (CF-UM-UP), Uni e si y o Minho, Campus
de Azu ém, 4800-058 Guima ães, Po ugal
3 LaPMET–Labo a o y o Physics o Ma e ials and Eme gen Technologies, Uni e si y o
Minho, B aga, Po ugal
pa icialexand [email protected]; [email p o ec ed]; joel[email p o ec ed]
Keywo ds: An i ungal coa ings, ZnO-based hin ilms, Gold nanopa icles (Au NPs)
2030 Sus ainable De elopmen Goals: SDG3, SDG11
Mic obial con amina ion on equen ly ouched su aces p esen s a global challenge wi h
implica ions o bo h public heal h and indus y. Mic oo ganisms adhe e and p oli e a e on
a ious inanima e su aces, including ables, sc eens, and doo knobs. Insu icien and
ine ec i e disin ec ion o hese su aces ans o ms hem in o ese oi s o mic obial g ow h.
The signi icance o high- ouch su aces in he ansmission pa hway o in ec ious diseases has
been accen ua ed by he COVID-19 pandemic. Consequen ly, he e is a p essing need o he
de elopmen o an imic obial coa ings o educe mic obial adhesion, he eby con ibu ing o
he mi iga ion o pa hogen ansmission h ough su aces.
This s udy ocuses on de eloping ZnO-based coa ings wi h an i ungal p ope ies. ZnO hin
ilms we e p oduced by eac i e magne on spu e ing wi h di e en hicknesses and gold
concen a ions. Then, hei an i ungal ac i i y was assessed by di ec con ac wi h he model
pa hogen, Candida albicans.
The de eloped hin ilms demons a ed signi ican an i ungal ac i i y, achie ing an 80%
educ ion in cell iabili y, ega dless o hickness, and o gold concen a ions below 15.4 a .%.
Pos -deposi ion annealing a 600 ˚C induced he o ma ion o supe icial Au NPs in samples
wi h CAu ≥ 15.4 a .%, he eby enhancing he an i ungal ac i i y o Au-ZnO compa ed o as-
deposi ed hin ilms. These indings sugges a su ace an i ungal ac i i y o ZnO-based hin
ilms and he syne gis ic impac o Au NPs.
The e o e, ZnO-based hin ilms exhibi high e iciency as an i ungal coa ings o di e se
su aces, p o ec ing agains mic obial con amina ion.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
16
TRANSCRIPTOMIC ANALYSIS OF C. ALBICANS CELLS IN DISTINCT METABOLIC
CONDITIONS
Alexand a Gomes-Gonçal es1, 2, Wou e Van Genech en3, Cláudia Ba a a-
An unes1, 2, Faezeh Ghasemi1, 2, Rosana Al es1, 2, Ma ga ida Casal1, 2, Joaquin
A iño4, Alis ai B own5, Pa ick Van Dijck3, Sand a Pai a1, 2
1 CBMA, Uni e si y o Minho, B aga, Po ugal
2 Ins i u e o Science and Inno a ion o Bio-sus ainabili y, Uni e si y o Minho, B aga,
Po ugal
3 Labo a o y o Molecula Cell Biology, Ins i u e o Bo any and Mic obiology, K.U. Leu en,
Leu en, Belgium
4 Ins i u de Bio ecnología i Biomedicina & Dep . de Bioquímica i Biologia Molecula ,
Uni e si a Au ònoma de Ba celona, Ba celona, Spain
5 MRC Cen e o Medical Mycology, Uni e si y o Exe e , Exe e , UK
[email protected] ; spai [email protected]
Keywo ds: Candida albicans, me abolic lexibili y, al e na i e ca bon sou ces
2030 Sus ainable De elopmen Goals: SDG3
Candida species a e among he mos common cause o ungal and nosocomial in ec ions in
humans. Thei capaci y o cause disease esides in he abili y o g ow wi hin he hos
en i onmen . To success ully p oli e a e in he human hos , Candida cells need o adap o a
b oad ange o cons ain s, including changes in nu ien s, en i onmen al pH, o a ack o he
immune sys em. All o hese cons ain s equi e apid and coo dina ed changes in me abolism
and physiology. In mos s udies, C. albicans cells a e g own on a i icial media condi ions ha
do no mimic physiological en i onmen s, lea ing impo an physiological e ec s la gely
unexplo ed. We ha e p e iously shown ha g ow h in he p esence o al e na i e ca bon
sou ces, such as lac a e in luences he beha io o Candida cells in an i ungal d ug esis ance.
In his wo k, we ha e pe o med a whole ansc ip ome analysis o C. albicans cells unde
ele an en i onmen al condi ions, using RNA-seq. He e, C. albicans cells we e g own in he
p esence o lac ic acid, an al e na i e ca bon sou ce equen ly p esen ed o C. albicans in he
hos en i onmen , ei he a pH 5 o pH 7, and se e al samples we e e ie ed and analyzed o
decode he pa hogen me abolic esponse.
Wi h his wo k, we p o ide in aluable insigh s in o he molecula pa hways in ol ed in lac a e-
dependen alkaliza ion o niche pH, which is an impo an ac o o i ulence and po en ially
o ungal su i al ollowing phagocy osis.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
17
FUNGI AND NUTRITION: EXPRESSION AND SUBCELLULAR LOCALIZATION
PATTERNS OF ATO2 TRANSPORT PROTEIN OF CANDIDA ALBICANS
Pa ícia A aíde1, 2*, Faezeh Ghasemi1, 2*, Cláudia Ba a a-An unes1, 2, Alexand a
Gomes-Gonçal es1, 2, Rosana Al es1,2, Ma ga ida Casal1, 2, Alis ai B own3,
Wou e Van Genech en4, Jana Nys en4, Pa ick Van Dijck4, Sand a Pai a1, 2
1 CBMA, Uni e si y o Minho, B aga, Po ugal
2 Ins i u e o Science and Inno a ion o Bio-sus ainabili y, Uni e si y o Minho, B aga,
Po ugal
3 MRC Cen e o Medical Mycology, Uni e si y o Exe e , Exe e , UK
4 Labo a o y o Molecula Cell Biology, Ins i u e o Bo any and Mic obiology, K.U. Leu en,
Leu en, Belgium
* These au ho s con ibu ed equally o he wo k
[email p o ec ed]; [email p o ec ed]; [email p o ec ed];
[email p o ec ed]; osanamaal [email protected]; [email p o ec ed];
[email p o ec ed]; [email p o ec ed]; jana.[email p o ec ed];
pa ick. andijck@kuleu en.be; [email p o ec ed]
Keywo ds: Yeas plasma memb ane p o eins, Candida albicans, O ganic Acids
2030 Sus ainable De elopmen Goals: SDG3
Candida albicans, a common commensal mic oo ganism wi hin he human body, assumes
pa hogenic po en ial in ins ances o immune sys em comp omise. In 2022, he Wo ld Heal h
O ganiza ion (WHO) highligh ed C. albicans as one o he highes conce ns, acco ding o he
g owing heal h p oblems, esis ance o an i ungals, and highe mo ali y a es associa ed wi h
his ungus. This oppo unis ic pa hogen can u ilize ca boxylic acids p oduced by he hos , such
as ace a e o lac a e, pa icula ly in en i onmen s wi h sho age o glucose sou ces. This
me abolic adap a ion signi ican ly con ibu es o he pa hogenici y o C. albicans.
In C. albicans, Jen anspo e s and po en ially Ace a e T anspo e O holog (A o) p o eins a e
esponsible o he up ake o ca boxyla es h ough he plasma memb ane (PM). The A o
p o eins a e membe s o he ace a e up ake anspo e (AceT ) amily comp ising 10 p o eins,
(A o1 – A o8) whose ole and comple e unc ion s ill emain unknown.
In his s udy, we aimed a cha ac e izing he exp ession p o iles and subcellula localiza ion o
CaA o p o eins, pa icula ly CaA o2, in dis inc me abolic and physiological condi ions. To
achie e his aim, we used he CRISPR-Cas9 sys em o gene a e a C. albicans s ain
ha bou ing, a he ch omosomal le el, an ATO2-GFP usion. A o2-GFP exp ession has been
e alua ed, by luo escence mic oscopy, in cells g own in he p esence o subs a es ha a e
usually p esen in human hos niches, like he gu .
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
18
DECODING ALKALI STRESS RESPONSES IN FUNGI
Cláudia Ba a a-An unes1, E ik de Huls e 2, Cla a Ca doso2, Bea iz-Conceição
Lei e1, Ví o Fe nandes1, Inês P. Ribei o1, 3, Geo ge Diallinas4, 5, Ma ga ida
Casal1, He nâni-Ge ós1, 6, 7, Joaquín A iño8, Robe Mans2, Sand a Pai a1
1 CBMA, Depa men o Biology, Uni e si y o Minho, 4710-057, B aga, Po ugal
2 Depa men o Bio echnology, Del Uni e si y o Technology, Van de Maasweg 9, 2629
HZ, Del , The Ne he lands
3 Li e and Heal h Sciences Resea ch Ins i u e (ICVS), School o Medicine, ICVS/3B’s-PT
Go e nmen Associa e Labo a o y, Uni e si y o Minho, 4710-057, B aga, Po ugal
4 Depa men o Biology, Na ional and Kapodis ian Uni e si y o A hens, Panepis imiopolis
15784, A hens, G eece
5 Ins i u e o Molecula Biology and Bio echnology, Founda ion o Resea ch and Technology,
70013, He aklion, G eece
6 Cen e o he Resea ch and Technology o Ag o-En i onmen al and Biological Sciences,
Uni e si y o T ás-os-Mon es and Al o Dou o, Vila Real, Po ugal
7 Cen e o Biological Enginee ing (CEB), Depa men o Biological Enginee ing, Uni e si y o
Minho, B aga, Po ugal
8 Ins i u de Bio ecnologia i Biomedicina & Depa amen de Bioquímica i Biologia Molecula ,
Uni e si a Au ònoma de Ba celona, Ce danyola del Vallès, Spain
[email p o ec ed]; bea izlei[email p o ec ed]; [email p o ec ed]
Keywo ds: T anspo e s, Endocy osis, Alkali s ess
2030 Sus ainable De elopmen Goals: SDG2, SDG5
Saccha omyces ce e isiae yeas cells alkalinize hei ex acellula en i onmen when
cul i a ed in monoca boxylic acids, as a sole ca bon sou ce. This e en igge s he emo al
om he plasma memb ane o he nu ien lac a e anspo e Jen1. The endocy ic
in e naliza ion o Jen1 ollowed by acuola deg ada ion depends on a unc ional Jen1
anspo e and on he in ol emen o he TORC1 signalling pa hway. Howe e , he links
be ween he physiological ele ance o his p ocess and he molecula mechanisms unde lying
i emain unknown.
In his wo k, S. ce e isiae cells s ably exp essing JEN1-GFP we e s udied using ae obic
ca bon limi ed con inuous cul u es in con olled bio eac o s, ollowed by a physiological,
biochemical and ansc ip omic analysis.
Ou da a showed ha Jen1 in e naliza ion unde alkali-g ow h condi ions is s ongly dependen
on he ex e nal pH, mos likely as a mechanism o a oid loss o cen al ca bon me aboli es.
We ha e iden i ied by ansc ip omic analysis a se o genes ha a e up egula ed a he speci ic
pH alue in which Jen1 s a s o be in e nalized.
Wi h his wo k, we we e also able o single ou how cells espond speci ically o en i onmen al
pH, p o iding new insigh s on he e ec o alkali s ess on Jen1 egula ion, bu also on he
gene al cellula esponse in euka yo ic cells.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
19
ANALYZING THE ROLE OF KEY AMINO ACID RESIDUES IN ASPERGILLUS NIGER
DCT-02 ON DICARBOXYLATE TRANSPORT
Al es, J.1, 2, Rendulić, T.1, 2, Casal, M.1, 2, Soa es-Sil a, I.1, 2
1 CBMA, Depa men o Biology, Uni e si y o Minho, Campus de Gual a , 4710-057 B aga,
Po ugal
2 Ins i u e o Science and Inno a ion o Bio-Sus ainabili y (IB-S), Uni e si y o Minho,
Po ugal
i[email p o ec ed]
Keywo ds: Ca boxylic Acids, Memb ane anspo e s
2030 Sus ainable De elopmen Goals: SDG12
DCT-02 is a dica boxyla e anspo e om Aspe gillus nige , membe o he Slow-Anion
Channel (SLAC1) amily. Exp ession o his anspo e in Saccha omyces ce e isiae enables
succina e sec e ion, being he di alen succina e anion he p e e ed anspo ed o m. Using
a combina ion o in silico ools and pheno ypical assays a s uc u al- unc ional analysis o he
expo e was done. The combina ion o DCT-02’s 3D s uc u e p edic ion, po e ou line,
molecula docking wi h succina e and conse a ion s a us o amino acid esidue in he
anspo e amily led o he selec ion o 22 esidues o si e-di ec ed mu agenesis. In o al, 32
mu an alleles we e unc ionally cha ac e ized by he e ologous exp ession in he S. ce e isiae
IMK982 s ain. Fluo escence mic oscopy was used o de e mine he exp ession and
localiza ion o he GFP- agged e sion o DCT-02 and mu an alleles. No ably, se e al o he
mu a ions on esidues ha we e highly conse ed esul ed in a loss o unc ion o he allele
exp essing cells, such as is he case o he R114, P204, R255, V274, G275, P276, P354,
F353 and N355 mu a ions, which p esen ed g ow h simila o S. ce e isiae IMK982 s ain
ans o med wi h he emp y ec o (p416GPD). Wi h he excep ion o he mu an allele o he
F279, R255, F353 esidues and he mu an s R114A, R114H and L210A all o he mu an
exp essing cells showed luo escence localised in he plasma memb ane. One mu an allele
when exp essed in Saccha omyces ce e isiae p esen s lowe g ow h compa ed o he wild-
ype allele exp essing s ain, which sugges s ha i is expo ing la ge amoun s o dica boxylic
acids ou side he cell. The same pheno ype was obse ed when cells we e g own on liquid
medium p esen ing a lowe g ow h a e compa ed o he wild- ype exp essing s ain. Fu he
s udies a e unde way o cha ac e ize succina e p oduc ion in his mu an . The esul s he e
ob ained a e c ucial o unde s and how expo e s wo k and ha e he po en ial o he
imp o emen o mic obial cell ac o ies enginee ed o he p oduc ion o ca boxylic acids.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
20
EXPLORING BENZO[A]PHENOXAZINE DERIVATIVES AS ANTIFUNGAL AGENTS
AGAINST CANDIDA
Ma ia Inês Pacheco1, 2, 3, Bá ba a S. G. Guima ães3, M. Samei o T. Gonçal es3,
Ma ia João Sousa1,2, Paula Sampaio1, 2
1 CBMA, Depa men o Biology, UMinho, Campus o Gual a , 4710-057 B aga, Po ugal
2 IB-S, UMinho, Campus o Gual a , 4710-057 B aga, Po ugal
3 Cen e o Chemis y (CQUM), Depa men o Chemis y, UMinho, Campus o Gual a ,
B aga
[email protected]; [email protected]; msamei [email protected] ;
[email protected] ; [email protected]
Keywo ds: Benzo[a]phenoxazine de i a i es, Candida spp, An i ungals
2030 Sus ainable De elopmen Goals: SDG3
Candida species, pa icula ly C. albicans, a e usually esponsible o wo isome in ec ions. The
ecen ise in non-albicans Candida species adds complexi y o ea men , gi en hei
unp edic able suscep ibili y o commonly used an i ungals. Benzo[a]phenoxazines a ise as
po en ial he apeu ic app oaches, due o hei es ablished an i ungal ac i i y agains S.
ce e isiae. Addi ionally, h ough modi ica ions in hei polycyclic sys em, benzo[a]phenoxazine
de i a i es wi h dis inc p ope ies a e ob ained. C34, wi h p opyl and dip opyl g oups a he
amino unc ions o 5- and 9-posi ions, espec i ely, demons a ed high an i ungal ac i i y
agains Candida, e en agains he mul i-d ug esis an C. au is. In his wo k, h ee compounds
wi h di e en a ia ions o C34’s s uc u e we e es ed: C35, wi h chlo op opyl g oup a he
amino o 5-posi ion o he he e ocycle sys em; A44 and A42, whe e he ee o a ion g oup a
9-posi ion in C34 and C35 was eplaced by a igid s uc u e con e ed by a julolidine moie y.
The an i ungal ac i i y o hese compounds was e alua ed agains ou een s ains om se en
Candida species, de e mining hei Minimum Inhibi o y Concen a ion (MIC), acco ding o he
Eu opean Commi ee on An imic obial Suscep ibili y Tes ing p o ocols o yeas s. We also
es ed hei cy o oxici y on a mac ophage-like cell line, h ough he MTT assay.
The o e all ange o MIC alues, conside ing all Candida species es ed, we e e y simila
be ween he compounds, excep o A42, which displayed he highes MIC alues, ollowed
closely by A44, indica ing ha he addi ion o he julolidine moie y did no con ibu e o an
enhancemen o he an i-Candida ac i i y. Compound C34, on he o he hand, displayed he
bes an i ungal ac i i y be ween all ou compounds, p esen ing he lowes MIC geome ic
mean, ollowed by C35, making hese compounds he mos sui able o de eloping an
an i ungal s a egy. This esul indica es ha he addi ion o he chlo op opyl g oup seems o
con ibu e o he an i-Candida e ec . Cy o oxici y assays showed ha C35 and A42 we e he
leas cy o oxic compounds, sugges ing ha he addi ion o he chlo op opyl g oup enhances
hei cy ocompa ibili y. Ne e heless, non- oxic concen a ions o all compounds we e below
C. albicans MIC alues.
Conside ing hese esul s, he design o new benzo[a]phenoxazine de i a i es wi h
po en ially imp o ed ac i i y agains Candida species can be add essed. Compounds C34
and C35 we e he mos sui able o an i ungal applica ions, conside ing hei syne gis ic
combina ion wi h known an i ungals, pa icula ly o mul i- esis an Candida species.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
21
GREEN SYNTHESIS OF PHOTOCATALYTIC NANOPARTICLES FOR THE
ELIMINATION OF EMERGING CONTAMINANTS IN WATER
Inês C. G. Espada2, Ped o M. Ma ins1, 2, S. Lance os-Méndez4, 5, 6
1 Cen e o Molecula and En i onmen al Biology, Gual a , B aga
2 Ins i u e o Science and Inno a ion on Bio-Sus ainabili y (IB-S), Gual a , B aga
3 Physics Cen e o Minho and Po o Uni e si ies (CF-UM-UP) and Labo a o y o Physics o
Ma e ials and Eme gen Technologies, LapMET, Gual a , B aga
4 BCMa e ials, Basque Cen e o Ma e ials, Applica ions and Nanos uc u es, UPV/EHU
Science Pa k, 48940 Leioa, Spain
5 Ike basque, Basque Founda ion o Science, 48009 Bilbao, Spain
[email p o ec ed] [email p o ec ed].p ; [email p o ec ed]nho.p
Keywo ds: G een syn hesis, Pho oca alysis, Wa e emedia ion
2030 Sus ainable De elopmen Goals: SDG6, SDG7, SDG12
Wa e pollu ion is one o oday's main en i onmen al p oblems. Eme ging pollu an s, especially
pha maceu icals, a e commonly ound in was ewa e due o hei ex ensi e use in e e yday
li e. Due o hei complex chemical s uc u es, hey a e qui e esilien o con en ional
ea men s. The e o e, pho oca alysis has eme ged as a solu ion o deg ade hese
con aminan s e ec i ely, equi ing only a pho oca alys and a sou ce o ul a iole o isible
adia ion. Ti anium dioxide (TiO2) is he mos s udied pho oca alys due o i s unique op ical
and oxidizing p ope ies, chemical and he mal s abili y, and low oxici y. I is usually
unc ionalised wi h gold (Au) nanopa icles o p e en elec on-hole pai ecombina ion and
ex end isible adia ion abso p ion. Howe e , con en ional syn hesis echniques use oxic
chemicals and p esen high ene gy consump ion. In o de o dec ease he en i onmen al
impac , g een syn hesis me hods ha u ilize na u al ex ac s and ecological sol en s ha e
been de eloped. The e o e, his s udy p oposes a g een syn hesis p ocedu e ha applies a
u in hyd a e, a la onoid ound na u ally in a ious plan s, as he educing agen in he g een
syn hesis o TiO2Au nanocomposi es.
Nanocomposi es wi h 1, 0.1, and 0.025 w % concen a ions we e syn hesised by he co-
p ecipi a ion me hod, adding he u in hyd a e o an aqueous solu ion con aining TiO2 P25 and
HauCl4. The chemical and physical p ope ies we e s udied h ough cha ac e isa ion
echniques such as TEM, XRD, DLS, ATR-FTIR, ze a po en ial and e lec ance spec oscopy.
I was con i med ha he addi ion o Au nanopa icles on o he su ace o TiO2 nanopa icles
ia a g een me hod does no al e he mo phology and c ys alline s uc u e o TiO2. The band
gap and s abili y we e imp o ed, wi h less agglome a e o ma ion obse ed.
A e wa ds, he nanocomposi es’ pho oca aly ic e iciency was es ed by deg ading he
pha maceu ical Cip o loxacin (CIP) unde ul a iole adia ion and simula ed sunligh . F om a
sus ainable s andpoin , he samples wi h 0.1 w % o Au nanopa icles p esen ed he bes
deg ada ion e iciencies while u ilizing he leas amoun necessa y o Au o a oid was e.
App oxima ely 75% o CIP was emo ed om he wa e o he deg ada ion unde UV adia ion,
while 73% o CIP was deg aded wi h i adia ion by simula ed sunligh .
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
22
CENTRO DE CIÊNCIA E TECNOLOGIA TÊXTIL
CENTRE FOR TEXTILE SCIENCE AND TECHNOLOGY
2C2T
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
29
SMART PRINTED TEXTILE DESIGN AND THE CREATION OF SYMBOLIC VALUE
THROUGH EMOTIONAL EXPERIENCE
Manoella Oli ei a, Joana Cunha, Isabel Cab al
Cen e o Tex ile Science and Technology, Azu ém, Guima ães
[email protected]; diascab [email protected], jcunh[email p o ec ed]nho.p
Keywo ds: Sma and In e ac i e Tex iles, Use Expe ience, Cul u al Sus ainabili y
2030 Sus ainable De elopmen Goals: SDG8, SDG9, SDG12
The inc ease in esea ch and de elopmen o ex iles inno a ions has been undamen al o
imp o ing echnologies in sma wea ables ma ke . This is expec ed o gain popula i y in 2030
and wo h mo e han US$4 billion. Sma ex iles e e o ex ile a i ac s ha in e ac – eac ing
o adap ing – wi h en i onmen al changes, ex ending o p o iding unc ionali y o common
ab ics. Despi e he ad an ages, he popula iza ion o hese echnologies s ill depends on
o e coming challenges, pa icula ly ela ed o usabili y. The in e ace design o hese p oduc s
p esen s i sel as a no able s a egy o inno a e. Among he p ocesses o inco po a ing
echnologies on he ex ile su ace, p in ing is one o he means ha o e s g ea in eg a ion
po en ial.
In addi ion o unc ional and p agma ic issues, design mus also conside he emo ional
dimension, he e o e i is ele an o unde s and he a ec i e esponses objec s p o ide. Since
i in luences he use psychological condi ions, hedonic app oach has been inc easingly
con empla ed in sma ex iles and wea able echnology ield.
Symbolic alue is app oached he e as a concep ual ocus o e alua e expe ience a an
emo ional le el and as a ele an pa h owa ds cul u al sus ainabili y – one o he p io i y
hemes o Uni ed Na ions Educa ional, Scien i ic and Cul u al O ganiza ion (UNESCO). In his
aspec , i is unde s ood ha awa eness and in o ma ion ela ed o memo y and cul u al
he i age can be accessed h ough p in ed pa e ns. In pa allel, pe cei ed symbolic alue
should encou age a longe p oduc li espan, due o he meaning i ca ies and he ela ionships
i ep esen s wi h he use , hus also con ibu ing o en i onmen al sus ainabili y.
In he ield o usabili y in p in ed sma ex iles o applica ions in echnical a eas, se e al
s udies ha e been ca ied ou . Howe e , he speci ici y o he in e sec ion be ween he a eas
o p in ed sma ex iles (no only as unc ional bu as holde s o aes he ic, symbolic and cul u al
alues) and use expe ience (UX), an in insic conce n o he disciplina y a ea o Design, s ill
lacks in es iga ions wi h g ea po en ial o be de eloped, which his p ojec p oposes.
This esea ch aims o explo e p in ing design o sma and in e ac i e ex iles – namely wi h
colou change beha iou –, as a means o inco po a ing symbolic and emo ional alues om
he UX pe spec i e.
The scien i ic con ibu ion is expec ed o be he expansion o knowledge in hese a eas, which
cu en ly lacks in e sec ional in-dep h s udy.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
30
EDUCATION FOR CIRCULAR ECONOMY: CONTRIBUTIONS TO THE DEVELOPMENT
OF INNOVATIVE TEACHING-LEARNING METHODOLOGIES AND STRATEGIES
So ia Mo ei a, An ónio Dinis Ma ques
2C2T - Cen o de Ciência e Tecnologia Têx il, Azu ém, Guima ães
[email p o ec ed]
Keywo ds: Ci cula Economy, Educa ion, Fashion Design
2030 Sus ainable De elopmen Goals: SDG12, SDG13
The ashion indus y posi ions i sel as one o he mos impo an and dynamic sec o s globally,
howe e , i is also one o he mos pollu ing. The excessi e p oduc ion o ashion i ems makes
i a signi ican consume o na u al esou ces and a majo p oduce o was e h oughou i s
alue chain.
I becomes impe a i e o ake ac ion o change he cou se o he eno mous impac i has on
he en i onmen , no only h ough public policies a ec ing he indus y bu also h ough
go e nmen o public ini ia i es ha aise awa eness among he popula ion abou he
excessi e impac o human ac i i y. Ci cula economy (CE) eme ges as an al e na i e o he
p e ailing model (Fas Fashion), cha ac e ized by ex ac ion, manu ac u ing, use, and
disposal, se ing as a guide o he ashion indus y, p omo ing he de elopmen o mo e
sus ainable p oduc s, and encou aging he euse and ecycling o p oduc s and aw ma e ials.
In his model, he concep o was e, much like in na u e, does no exis , as e e y hing is
pe cei ed as a esou ce.
Fo he ansi ion om a "c adle o g a e" model o a "c adle o c adle" model (B aunga and
McDonough) o be solidi ied, consume s o ashion i ems will also need o change hei
pu chasing beha iou s. The bidi ec ional ela ionship be ween supply and demand is c ucial
o he success ul implemen a ion o he CE in he ashion indus y. The e o e, i is impe a i e
ha consume s ha e a p ope unde s anding o hei impo ance in his p ocess, wi h educa ion
playing a signi ican ole in aising awa eness among he you h. Educa ion o sus ainabili y
aims o b oaden he ho izons o young people ega ding his issue and he ole hey play wi h
he choices hey make in hei daily li es.
In a gene al sense, he p esen ed esea ch ul ima ely aims o de elop inno a i e eaching-
lea ning me hodologies and s a egies o he CE, o be implemen ed wi h high school
s uden s. These me hodologies and s a egies will d aw inspi a ion no only om wha is
al eady being de eloped in he con ex o o mal educa ion o his le el, speci ically in he
Fashion Design Technical Cou se, bu also om na ional and in e na ional ini ia i es ocusing
on ashion and sus ainabili y, as well as in design me hods and echniques in ashion design.
Me hodologically, he esea ch employs mixed me hods, bo h in e en ionis and non-
in e en ionis , and quali a i e and quan i a i e echniques o add ess he esea ch ques ion
and con i m he esea ch a gumen based on he p emise ha he ac i i ies de eloped and
implemen ed in he class oom will ein o ce u u e sus ainable beha iou s and in e en ions
among young people.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
31
CENTRO DE ENGENHARIA BIOLÓGICA
CENTRE OF BIOLOGICAL ENGINEERING
CEB
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
32
MICROBIAL LIPIDS PRODUCTION BY YARROWIA LIPOLYTICA STRAINS FROM
LIGNOCELLULOSIC BIOMASS HYDROLYSATES
B una Dias1, Ma lene Lopes1, 2, Rosa Rod íguez-Jasso3, Isabel Belo1, 2
1 Cen e o Biological Enginee ing, Uni e si y o Minho, Campus de Gual a , B aga, Po ugal
2 LABBELS – Associa e Labo a o y, B aga/Guima ães, Po ugal
3 Bio e ine y G oup, Food Resea ch Depa men , Au onomous Uni . Coahuila, Sal illo, Coahuila,
Mexico
[email p o ec ed]; ma l[email p o ec ed]; od i[email p o ec ed];
[email protected]
Keywo ds: Lignocellulosic biomass hyd olysa es, Mic obial lipids, Ya owia lipoly ica
2030 Sus ainable De elopmen Goals: SDG7, SDG13
In ecen yea s, ene gy c ises and en i onmen al conce ns wi h ossil uels ha e d i en
esea ch in o al e na i e lipidic sou ces o adi ional ege able oils o he bio uels indus y.
Mic obial lipid p oduc ion om lignocellulosic biomass (LB) eme ges as a p omising aw
ma e ial o he biodiesel p oduc ion. The ecalci an s uc u e o LB equi es p e ea men s o
elease monome ic assimilable suga s o mic obial species. Howe e , hese p e ea men s
gene a e some undesi ed compounds wi h an imic obial ac i i y.
This esea ch aims o assess he po en ial o Y. lipoly ica s ains o use lignocellulosic biomass
hyd olysa es (LBH) wi hou de oxi ica ion s eps o lipid- ich biomass p oduc ion. Fi s ly, he
ole ance o h ee Y. lipoly ica s ains o undesi ed compounds (ace ic acid, o mic acid,
u u al, and 5-HMF) was assessed in mic opla e wells. The p oduc ion o lipid- ich biomass o
chosen s ains (W29 and NCYC 2904) was alida ed in s i ed- ank bio eac o (STR) using
syn he ic medium mimicking an LBH. In ba ch cul u es, he W29 s ain a ained he lipids
con en and concen a ion o 29 % (w/w, d y basis) and 4.7 g/L, espec i ely, while he NCYC
2904 s ain eached 53 % (w/w) and 10.9 g/L. In he epea ed ba ch cul u es, he lipids
p oduced by he W29 s ain inc eased o 6.6 g/L, while wi h he NCYC 2904 s ain he lipids
p oduc ion a ained 13.9 g/L.
The abili y o W29 s ain o g ow and p oduce lipids was p o en in eucalyp us ba k hyd olysa e
(EBH) in STR expe imen s. Rega dless o he o al suga s (65 g/L o 106 g/L) and an imic obial
compounds concen a ion o EBH, he yeas success ully g ew in undilu ed and unde oxi ied
EBH. The maximum lipids concen a ion inc eased om 5.6 g/L (65 g/L o o al suga s) o 8.1
g/L (106 g/L o o al suga s) due o he high biomass p oduc ion in mo e concen a ed EBH.
Ya owia lipoly ica NCYC 2904, g own in undilu ed and unde oxi ied oli e ee p uning
hyd olysa e (129 g/L o o al suga s), accumula ed 35 % (w/w) o lipids, co esponding o a
concen a ion o 10 g/L. Lipids om bo h s ains we e highly unsa u a ed, mainly composed o
oleic acid, indica ing hei sui abili y as eeds ock o he biodiesel indus y.
This esea ch highligh s he ex ao dina y abili y o bo h Y. lipoly ica s ains in u ilizing LBH o
mic obial lipids p oduc ion, he eby p omo ing sus ainable biodiesel p oduc ion om
lignocellulosic eeds ocks. This app oach no only educes p ocess cos s bu also minimizes
esou ce was age, aligning wi h he p inciples o a ci cula economy. Fu he mo e, i aligns
wi h he objec i es o The Eu opean G een Deal, p omo ing he ansi ion om ossil uels o
bio uels and con ibu ing o he educ ion o global gas emissions.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
33
EXPLORING YARROWIA LIPOLYTICA STRAINS FOR BIOCONVERSION OF
HYDROCARBONS INTO HIGH-VALUE COMPOUNDS
Síl ia Mi anda1, Ma ia Alice Coelho2, Isabel Belo1, 3, Ma lene Lopes1, 3
1 Cen e o Biological Enginee ing, Uni e si y o Minho, Campus de Gual a , B aga, Po ugal
2 Depa amen o Biochemical Enginee ing, UFRJ, Cidade Uni e si á ia, Rio de Janei o,
B azil
3LABBELS – Associa e Labo a o y, B aga/Guima ães, Po ugal
[email p o ec ed]; ali[email p o ec ed]; [email p o ec ed]; [email p o ec ed]
Keywo ds: Hyd oca bons, Ya owia lipoly ica, Mic obial lipids
2030 Sus ainable De elopmen Goals: SDG7, SDG12, SDG13
Economic ac i i ies a e s ongly dependen on he use o ossil uels and pe oleum-de i ed
p oduc s. Hence, huge amoun s o hyd oca bon-pollu ed was ewa e a e p oduced in se e al
indus ies (pe ochemical indus ies, au omo i e and au omobile epai s a ions, e c.). The
imp ope disposal o his was ewa e p esen s a subs an ial en i onmen al challenge. Mic obial
deg ada ion o hyd oca bons o e s an al e na i e o he physicochemical me hods commonly
employed and se e al wo ks ha e been epo ed mainly wi h bac e ial species.
This esea ch e alua ed he po en ial o using a yeas , Ya owia lipoly ica, o assimila e
hyd oca bons and p oduce aluable compounds. This oleaginous yeas species has an
in ense sec e o y ac i i y and demons a es an ex ao dina y capaci y o use a wide ange o
hyd ophobic compounds, including non- e ined ones.
Fi s ly, six Y. lipoly ica s ains we e s udied o hei abili y o assimila e 5 g·L-1 hexadecane as
he sole ca bon sou ce. Y. lipoly ica CBS 2075 s ood ou as he mos p omising in hexadecane
consump ion and biomass p oduc ion, and u he expe imen s we e ca ied ou in a s i ed-
ank bio eac o (STR) o e alua e he e ec o he olume ic oxygen ans e coe icien (kLa).
Inc easing kLa om 11 h-1 o 132 h-1 imp o ed he hexadecane assimila ion a e, biomass inal
concen a ion, and lipids syn hesis. The supplemen a ion o medium wi h co n s eep liquo , a
low amoun o (NH4)2SO4, and an inc ease in he C/N a io boos ed he p oduc ion o mic obial
lipids (2.1 g·L-1) and p o ease (526 U·L-1).
The yeas Y. lipoly ica also demons a ed e icien assimila ion o a hyd oca bon mix u e (2 g·L-
1 dodecane, 2 g·L-1 hexadecane, and 2 g·L-1 hexadecene). In ba ch cul u es, wo Y. lipoly ica
s ains g ew wi hou a lag phase, and dissol ed oxygen sa u a ion o 30 % was enough o
p e en he limi a ion o lipids and p o ease p oduc ion. Addi ionally, he s a egy o s epwise
ba ch cul u es wi h 3 pulses o hyd oca bon mix u e (24 g·L-1 o hyd oca bons in o al)
enhanced biomass p oduc ion, and high p o ease ac i i ies (≈ 3000 U·L-1) and lipids
concen a ions o 3.4 g·L-1 and 4.3 g·L-1 we e a ained using Y. lipoly ica CBS 2075 and DSM
8218s ains, espec i ely. Lipids o he CBS 2075 s ain we e ich in C16:0 and C18:1,
esembling he composi ion o palm oil, adi ionally used in he biodiesel indus y. Lipids om
he DSM 8218 s ain we e mainly composed o C16:0 and C16:1, a aluable monounsa u a ed
a y acid employed in he pha maceu ical indus y.
This esea ch demons a es he capabili y o Y. lipoly ica o biocon e hyd oca bons in o high-
alue compounds, aligning wi h he p inciples o bio e ine y and ci cula bioeconomy.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
34
VALORIZATION OF RED, GREEN AND BROWN SEAWEEDS THROUGH SOLID-
STATE FERMENTATION TO IMPROVE ITS NUTRITIONAL VALUE
Ma a Fe ei a1, José Manuel Salgado2, Helena Pe es3, 4, Isabel Belo1, 5
1 Cen e o Biological Enginee ing, Uni e si y o Minho, Campus de Gual a , B aga, Po ugal
2 Bio ecnia G oup, Depa men o Chemical Enginee ing, UVigo (Campus Ou ense), Spain
3 CIMAR/CIIMAR, Uni e sidade do Po o, 4450-208 Ma osinhos, Po ugal
4 Depa amen o de Biologia, Faculdade de Ciências, Uni e sidade do Po o, Po o, Po ugal
5 LABBELS – Associa e Labo a o y, B aga/Guima ães, Po ugal
ma a. e ei [email protected] ; jmsalgado@u igo.gal; pe eshelena@ c.up.p ; ibel[email p o ec ed]nho.p
Keywo ds: Seaweeds, Solid-s a e e men a ion, Ca bohyd ases
2030 Sus ainable De elopmen Goals: SDG2, SDG12, SDG14
Seaweeds a e p omising ing edien s o aqua eeds, bu i s use may be limi ed due o hei
ecalci an polysaccha ide s uc u e. To dis up his s uc u e, a bio echnological app oach such
as solid-s a e e men a ion (SSF) can be applied, using ilamen ous ungi o p oduce ca bohyd ases
(xylanase, cellulase, and β-glucosidase) ha deg ade seaweeds biomass.
In his s udy, he p oxima e composi ion o i e seaweeds (G acila ia sp., Po phy a dioica, Codium
omen osum, Ul a igida and Ala ia esculen a) we e e alua ed. SSF was pe o med using
Aspe gillus ibe icus MUM 03.49 and A. nige CECT 2915 wi h 5 g o each d y seaweed, wi h ini ial
mois u e o 75% w/w (we basis), a 25 ºC o 7 days. A e SSF, c ude p o ein and ca bohyd a e
con en s we e de e mined in e men ed solid, and an aqueous ex ac ion was pe o med o assess
ca bohyd ases ac i i y.
Red seaweeds had he highes p o ein con en , specially G acila ia sp. (28 % w/w d y solid)
ollowed by P. dioca (24 % w/w). Compa ing o he o he seaweeds, C. omen osum p esen ed he
highes lipids con en o 6 % (w/w).
Maximum xylanase and β-glucosidase ac i i ies we e ob ained using U. igida as subs a e o SSF
wi h bo h ungi. Cellulase ac i i y was highe in SSF o G acila ia sp. and U. igida wi h A. nige
han when using he o he seaweeds. P o ein con en inc eased by SSF o C. omen osum wi h A.
ibe icus and by SSF o U. igida wi h A. ibe icus and A. nige . Ca bohyd a e con en dec eased
a e SSF o U. igida using bo h ungi.
Fu he mo e, Gelidium co neum by-p oduc (GBP) ob ained a e aga ex ac ion was also used o
alue-added compound p oduc ion h ough SSF wi h he same ungal s ains. GBP was used as
subs a e o SSF unsupplemen ed, supplemen ed wi h Mandel sal solu ion, and in a 50% (w/w)
mix u e o GBP wi h ege able cakes by-p oduc s and U. igida. The changes in c ude p o ein and
ca bohyd ases p oduc ion in he e men ed biomass we e assessed. The maximum xylanase
ac i i y o a ound 500 Uni s pe g am o d y solid (U g-1) was achie ed wi h SSF o GBP mixed wi h
sun lowe cake using A. nige , while he mix u e be ween GBP and apeseed cake led o he highes
cellulase ac i i y (382 U g-1). P o ein con en inc eased 30%, 18% and 15% a e SSF wi h A. nige
in GBP mixed wi h ice b an, apeseed, and sun lowe cakes, espec i ely.
Biop ocessing o seaweeds o seaweed by-p oduc using SSF is an en i onmen ally iendly
s a egy o p oduce high- alued enzymes simul aneously enhancing nu i ionally hese biomasses
o be included in aqua eeds.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
35
THE HIDDEN POTENTIAL OF HYPERSALINE ENVIRONMENTS: EXTREMOPHILES
AS SOURCE OF NEW BIOSURFACTANTS
Joana S. Gomes1*, Cá ia San os-Pe ei a1, 2*, Joana Sousa1, Ma a Simões3,
And é An unes3, Rica do F anco-Dua e4, 5, Sa a C. Sil é io1, 2, Lígia R.
Rod igues1, 2
* These au ho s con ibu ed equally o his wo k
1 Cen e o Biological Enginee ing, Uni e si y o Minho, Campus de Gual a , B aga, Po ugal
2 LABBELS, Uni e si y o Minho, B aga, Po ugal
3 S a e Key Labo a o y o Luna and Plane a y Sciences, Macau Uni . o S&T, Macau, China
4 CBMA, Uni e si y o Minho, B aga, Po ugal
5 IB-S, Uni e si y o Minho, B aga, Po ugal
[email protected] ; ca iape ei [email protected] ; [email protected] ;
msimoes@mus .edu.mo; aglan une[email p o ec ed]u.mo; ica do ilipedua [email protected] ;
[email p o ec ed]; [email p o ec ed]
Keywo ds: Me agenomics, Biosu ac an s, Hype saline en i onmen s
2030 Sus ainable De elopmen Goals: SDG12, SDG13, SDG17
The cu en awa eness on clima e change is p omp ing a g owing in e es in inding sus ainable
al e na i es o eplace he pe oleum-based su ac an s ha a e widely used in he daily li e
p oduc s. Biosu ac an s eme ge as eco- iendly al e na i es o he con en ional su ac an s, since
hey a e su ace-ac i e molecules syn hesized by mic oo ganisms wi h lowe en i onmen al
impac . These molecules ha e applica ion in se e al ields including cosme ics, pha maceu ical,
de e gen s, ood, and ex ile indus ies. Lack o well-known and cha ac e ised s uc u e di e si y
associa ed wi h hei high p oduc ion and eco e y cos s a e impac ing he widesp ead use o
biosu ac an s. Ex eme en i onmen s like hose ound in hype saline si es a e a good sou ce o
unique mic obial di e si y (ex emophiles) capable o p oduce new compounds, including
biosu ac an s. In his con ex , he B3iS – “Biodi e si y and Biop ospec ion o Biosu ac an s In
Saline en i onmen s” p ojec aims o unco e new biosu ac an s om hype saline en i onmen s
ha can be p omising eco- iendly al e na i es o he con en ional su ac an s, o ul ima ely mi iga e
hei en i onmen al bu den.
Fo ha pu pose, cul u e-dependen and cul u e-independen (me agenomics) s a egies we e
applied o explo e he ull mic obial di e si y o ou selec ed en i onmen s: A ei o and Rio Maio
sal e ns (Po ugal), Peña Hueca lagoon (Spain) and Cape Ve de sal e ns (Sal Island). In he
cul u e-dependen app oach se e al halophilic mic oo ganisms we e isola ed, sc eened o
biosu ac an p oduc ion and hei genomes sequenced o unc ional analysis and iden i ica ion o
po en ial biosu ac an biosyn he ic pa hways. On he o he hand, in he cul u e-independen
app oach, he o al genomic DNA om he mic obial communi ies o each selec ed en i onmen s
was ex ac ed and used o cons uc me agenomics lib a ies ha we e unc ionally sc eened o
iden i y po en ial biosu ac an -p oducing clones. The physicochemical analysis e ealed an
in e es ing di e si y in e ms o salini y, pH, and ionic con en o he di e en sampling si es. The
s a egies ca ied ou allowed he iden i ica ion o no el mic oo ganisms and me agenomic clones
wi h po en ial o p oduce p omising biosu ac an s. The sequence me agenomics app oach also
showed an en ichmen in genes coding o biosu ac an s wi h speci ic ca ego ies appea ing only
in some loca ions. This in o ma ion was ob ained by mapping he isola ed me agenomes agains
he BioSu DB da abase. O e all, he esul s co obo a e he ele ance o he B3iS p ojec in
iden i ying no el biosu ac an s wi h a ac i e indus ial p ope ies by mining hype saline
en i onmen s.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
36
ASSESSMENT OF THE POTENTIAL OF NATURAL MICROBIOMES FOR
MICROPLASTICS BIODEGRADATION: A COMPARATIVE STUDY OF POLY(Ε-
CAPROLACTONE), POLYETHYLENE AND POLYETHYLENE TEREPHTHALATE
C is ina I.S. Pi es1, 2, Luís Cos a1, 2, Sónia G. Ba bosa1, 2, João Ca los Sequei a1,
2, Diogo Cache as1, 2, José P. F ei as1, 2, Gilbe o Ma ins1, 2, Ana Ve a
Machado3, Ana J. Ca alei o1, 2, And eia F. Sal ado 1, 2
1 CEB - Cen e o Biological Enginee ing, Uni e si y o Minho, B aga, Po ugal
2 LABBELS – Associa e Labo a o y, B aga/Guima ães, Po ugal
3 IPC - Ins i u e o Polyme s and Composi es, Uni e si y o Minho, Guima ães, Po ugal
[email p o ec ed]; luiscos [email p o ec ed]; [email p o ec ed];
jsequei [email protected] ; diogomcache [email protected]; jps ei [email protected];
gilbe o.ma i[email p o ec ed]; [email p o ec ed]; [email p o ec ed];
[email p o ec ed]
Keywo ds: Mic oplas ics, Biodeg ada ion, Mic obiomes
2030 Sus ainable De elopmen Goals: SDG3, SDG6, SDG14
Plas ics ha e e ol ed in o an essen ial componen o mode n socie y, assuming impo an oles ac oss
di e se economic sec o s. Consequen ly, plas ic was e accumula ion has become a se ious
en i onmen al p oblem, impac ing bo h wildli e and human heal h. Mic obial deg ada ion o bo h
syn he ic and biodeg adable plas ics is a p omising en i onmen ally iendly app oach o ackle his
issue.
This s udy del es in o he capaci y o na u al mic obiomes, ound in land ill leacha e and ma ine
sedimen , o biodeg ade mic opa icles o polye hylene (PE), polye hylene e eph hala e (PET), and
polycap olac one (PCL). Mic ocosms we e inocula ed wi h he wo mic obiomes, and he assays we e
pe o med unde ae obic and anae obic condi ions, a he mophilic (55 °C) and mesophilic (37 °C)
empe a u es. Plas ics biodeg ada ion was ollowed o e ime by measu ing oxygen consump ion o
me hane p oduc ion.
PCL was ex ensi ely biodeg aded by he land ill leacha e, eaching 99±7% and 87±19% unde ae obic
and anae obic condi ions, espec i ely, wi hin 50-60 days. This polyme was also biodeg aded by he
ma ine sedimen unde ae obic condi ions (i.e., 78±3%) wi hin he same ime pe iod, bu only 3±0.3%
biodeg ada ion was a ained in he anae obic assays. Limi ed biodeg ada ion was e i ied o PE and
PET wi h bo h inocula.
Gi en he PCL biodeg ada ion capabili y o land ill leacha e, mic obial communi ies in bo h anae obic
and ae obic assays we e in es iga ed. Cop o he mobac e sp. eme ged as a p e alen mic oo ganism,
ep esen ing 6.8% and 28% o ela i e abundance (based on 16S RNA sequencing o o al mic obial
communi y) in anae obic and ae obic incuba ions, espec i ely. This shows i s po en ial ole in PCL
biodeg ada ion ac oss di e se condi ions. Addi ionally, Me hano he mobac e sp. eme ged as he
p edominan me hanogenic mic oo ganism in he anae obic communi y, (21% o o al mic obial
communi y). Since bac e ia om Cop o he mobac e genus a e capable o hyd ogen p oduc ion, and
Me hano he mobac e is a hyd ogen sca enge , syn ophic in e ac ions a e possibly occu ing, which is
a no el aspec in mic oplas ics biodeg ada ion. In he ae obic communi y, ungi om Exophiala (41%
18S RNA ela i e abundance), Penicillium (17%), and Muco (18%) gene a we e also abundan ,
sugges ing a possible ole in PCL deg ada ion. Consequen ly, ae obic PCL biodeg ada ion by land ill
leacha e likely in ol es a syne gis ic ne wo k o ungi and bac e ia, ei he ope a ing independen ly o
in e ac ing wi hin a complex mic obial ma ix.
These indings ad ance cu en knowledge on mic oplas ics biodeg ada ion. The insigh s de i ed om
his s udy may pa e he way o he de elopmen o mo e sus ainable app oaches o plas ic was e
managemen , emphasizing he c ucial conside a ion o speci ic en i onmen al condi ions and mic obial
in e plays in biodeg ada ion s udies.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
37
DEVELOPMENT OF FOAM-FREE BIOSURFACTANT PRODUCTION PROCESSES
USING BACILLUS LICHENIFORMIS STRAINS
Edua do Leal1, 2, José A. Teixei a1, 2, Edua do J. Gudiña1, 2
1 CEB − Cen e o Biological Enginee ing, Uni e si y o Minho, 4710-057 B aga, Po ugal
2 LABBELS − Associa e Labo a o y, B aga/Guima ães, Po ugal
[email p o ec ed]; ja ei[email p o ec ed]; [email p o ec ed]
Keywo ds: Lichenysin, Lipopep ide, Su ac an .
2030 Sus ainable De elopmen Goals: SDG6, SDG9, SDG12, SDG13
Mic obial biosu ac an s (BS) a e conside ed en i onmen ally iendly al e na i es o syn he ic
su ac an s in nume ous applica ions. Howe e , he main bo lenecks o hei widesp ead use
a e he high p oduc ion cos s and he lack o e ec i e p ocesses o hei p oduc ion a
indus ial scale. BS p oduc ion using con en ional ae a ed bio eac o s esul s in excessi e
oaming, due o he combina ion o ai injec ion and he ensioac i e p ope ies o BS. Al hough
se e al al e na i es ha e been p oposed o o e come his p oblem, none o hem p o ed o
be sa is ac o y. A no widely explo ed app oach is he de elopmen o oam- ee BS p oduc ion
p ocesses, which equi es he iden i ica ion and cha ac e iza ion o app op ia e
mic oo ganisms. Fo ha pu pose, eigh Bacillus licheni o mis s ains we e e alua ed o BS
p oduc ion unde oxygen-limi ing condi ions. The bac e ial s ains we e g own in se um lasks
using a mine al medium (MSM1) con aining glucose as ca bon sou ce, and NaNO3 and NH4Cl
as ni ogen sou ces (ni a e was used also as al e na i e elec on accep o ). Among he
di e en s ains, only wo educed he su ace ension (ST) o he cul u e medium o alues
below 30 mN/m, indica ing BS p oduc ion unde oxygen-limi ed condi ions. The bes esul s
we e ob ained wi h B. licheni o mis EL3, isola ed om an oil ese oi , which educed he ST
om 59.8 ± 0.8 mN/m o 29.3 ± 0.3 mN/m in 24 h. BS p oduc ion unde oxygen-limi ing
condi ions by he s ain EL3 was alida ed in bio eac o assays, using he cul u e medium
MSM1. A e op imizing he ope a ional condi ions, glucose concen a ion, and inoculum
s a egy, B. licheni o mis EL3 p oduced 75 ± 3 mg BS/L in 43 h. The pu i ied BS (mos p obably
he lipopep ide lichenysin) exhibi ed excep ional su ace-ac i e p ope ies, wi h minimum ST
alues (29 mN/m) and a c i ical micelle concen a ion (27 mg/L) simila o hose achie ed wi h
comme cial su ac in (p oduced by Bacillus sub ilis), he mos powe ul BS known so a .
Fu he mo e, BS yield pe subs a e (YP/S= 0.007 g BS/g glucose) was simila o he igu es
epo ed o B. sub ilis s ains g own in simila condi ions, whe eas BS yield pe biomass (YP/X=
0.755 g BS/g biomass) and speci ic BS p oduc i i y (qBS= 0.018 g BS/(g biomass × h)) we e
almos h ee imes highe when compa ed o p e ious epo s. In summa y, he esul s
ob ained indica e ha B. licheni o mis EL3 is a p omising candida e o he de elopmen o
oam- ee BS p oduc ion p ocesses a indus ial scale.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
38
UNCOVERING NOVEL CARBOHYDRATE-DEGRADING ENZYMES FROM
COMPOSTING UNITS THROUGH METAGENOMIC STRATEGIES
Joana Sousa1, Cá ia San os-Pe ei a1, 2, Ângela M. A. Cos a1, And éia O.
San os1, Joana Gomes1, Joana L. Rod igues1, 2, Edua do J. Gudiña1, 2, João
Linha es3, Rica do F anco-Dua e4, 5, Sé gio F. Sousa6, Lígia R. Rod igues1, 2,
Sa a C. Sil é io1, 2
1 Cen e o Biological Enginee ing, Uni e si y o Minho, Campus de Gual a , B aga, Po ugal
² LABBELS - Associa e Labo a o y, B aga/Guima ães, Po ugal
3 Cen e o Physics, Uni e sidade do Minho, Campus de Gual a , 4710-057 B aga, Po ugal
4 CBMA - Cen e o Molecula and En i onmen al Biology, Uni e si y o Minho, Campus de
Gual a , 4710-057 B aga, Po ugal
5 IB-S - Ins i u e o Science and Inno a ion o Bio-Sus ainabili y, Uni e si y o Minho,
Campus de Gual a , 4710-057 B aga, Po ugal
6 LAQV/REQUIMTE BioSIM – Depa men o Biomedicine, Facul y o Medicine, Uni e si y o
Po o, Po o 4200-319, Po ugal
[email protected] ; ca iape ei [email protected] ; angelacos [email protected];
[email p o ec ed]; joana.[email p o ec ed]; joana.joanaluci[email p o ec ed];
[email p o ec ed]; jli[email p o ec ed]; ica do ili[email p o ec ed];
[email p o ec ed]; [email p o ec ed]; sa asi[email p o ec ed]
Keywo ds: Me agenomics, Compos ing, Ca bohyd a e-deg ading enzymes
2030 Sus ainable De elopmen Goals: SDG9, SDG12
The as di e si y o unexplo ed mic obial communi ies inhabi ing he ex eme en i onmen s
o ou plane d i es he sea ch o no el and in e es ing enzymes. Compos ing uni s ha
manage lignocellulosic esidues exhibi a high mic obial di e si y and ep esen a sui able
ese oi o obus ca bohyd a e-deg ading enzymes (CAZymes). These enzymes a e
conside ed impo an ca alys s in he biocon e sion o lignocellulosic biomass in o added- alue
biop oduc s ha hold p ac ical applica ions in nume ous indus ies.
Me agenomics is a powe ul cul u e-independen echnique o un a el he di e si y and
unc ion o mic obial communi ies h ough he analysis o DNA ob ained om en i onmen al
samples. Two di e en me hodologies ha e been p oposed, namely unc ion- and sequence-
based me agenomics. The unc ional app oach enables he disco e y o no el enzymes and
p o ides p elimina y insigh s in o hei ca aly ic ac i i ies and physicochemical cha ac e is ics.
On he o he hand, he sequence-based s udies allow inding new gene sequences ha e eal
simila i ies wi h he anno a ed genomes a ailable in he da abases.
Unde he scope o he Lignozymes p ojec , compos samples we e collec ed, du ing he
he mophilic phase o he p ocess, om di e en Po uguese compos ing uni s, which handle
di e en ypes o was e. The o al me agenomic DNA was ex ac ed and he po en ial o
compos ing samples as ese oi s o e icien CAZymes was success ully e alua ed using
me agenomic ools. Rega ding he axonomic classi ica ion o he pu a i e enzymes ound in
he samples’ me agenomes, CAZymes la gely belonged o he Bac e ia domain. Fu he mo e,
unc ional sc eening e ealed ha he compos ing samples showed a g ea abundance o
glycoside hyd olases, pa icula ly cellulases and xylanases. This wo k con i ms he ichness
o compos ing habi a s as a p omising sou ce o bioca alys s specialized in he deg ada ion o
lignocellulosic biomass h ough e icien and sus ainable s a egies.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
45
STRATEGY TO SAFEGUARD CORK AND RUBBER APPLICATION’S BEAUTY AND
LONGEVITY: SUSTAINABLE THIN FILM DEPOSITION
B. Tiss1, C. Mansilla2, D. Ma ínez1,3, L. Cunha1
1 Physics Cen e o Minho and Po o Uni e si ies -CF-UM-UP, Campus de Gual a , 4710-057
B aga, Po ugal
2 CTECHnano Coa ings Technologies S.L., Tolosa Hi ibidea 76, 20018, San Sebas ián,
Spain
3 Depa men o Ma e ials Resea ch and Technology, Luxembou g Ins i u e o Science and
Technology (LIST), 28 a enue des Hau s-Fou neaux, Esch-su -Alze e L-4362, Luxembou g
s
[email p o ec ed] / b iss@ isica.uminho.p ; c.mansil[email p o ec ed]; [email p o ec ed];
lcunha@ isica.uminho.p
Keywo ds: Co k and ubbe , Magne on spu e ing, TiO2 and ZnO hin ilms
Op imizing ma e ials’ pe o mance while p ese ing essen ial bulk cha ac e is ics o en
in ol es su ace modi ica ion h ough hin ilm deposi ion. Howe e , when dealing wi h delica e
o in ica e subs a es, his p ocess becomes mo e challenging. Take, o example, co k and
ubbe —na u al, polyme ic ma e ials widely used in a ious applica ions, including wine
s oppe , loo game and yoga ma , SpaceX ocke s, e c. When exposed o sunligh o subjec ed
o ic ion and mechanical wea , hese ma e ials unde go isible aging, mani es ed as
discolo a ion, sc a ches, o e en c a e s. Sa egua ding such subs a es agains hese ha sh
condi ions necessi a es a s a egic solu ion—coa ing hem wi h a compa ible hin ilm ha
ein o ces p o ec ion wi hou comp omising hei inhe en quali ies. This app oach ensu es
du abili y and longe i y, add essing he unique challenges posed by sensi i e and complex
ma e ials like co k and ubbe . Bu bo h ma e ials a e di icul o coa . Besides empe a u e
sensi i i y, hey show g ea de o ma ion capabili y, which o ces he deposi ed coa ing o be
lexible and adhe en . In addi ion, hey show high oughness, and he polishing is e y
challenging, o e en impossible. Despi e hese complexi ies, his wo k achie ed a
b eak h ough by e ec i ely deposi ing TiO2 and ZnO hin ilms, opaque o UV ye anspa en
o isible ligh , u ilizing he magne on spu e ing echnique. This inno a i e app oach is
s a egically employed o p ese e he inhe en quali ies o ubbe and co k. In addi ion, his
s udy p o ides a de ailed examina ion o he physical cha ac e is ics o he deposi ed ilms,
showcasing he esilience and adap abili y o he coa ings in esponse o he unique ea u es
o ubbe and co k. No ably, he esul s pe aining o UV ligh and mechanical wea p o ec ion
a e elucida ed, o e ing a comp ehensi e unde s anding o he p ac icali y and e icacy o his
ad anced p o ec i e coa ing s a egy. Amo im Co k Composi es and Flowco a e wo
companies’ membe s o his p ojec . The i s one belongs o Co icei a Amo im, he mos
impo an company in he wo ld ega ding co k manu ac u ing, being Po ugal is he main
p oduce and expo e o co k in he wo ld. Flowco is a company de o ed o ci cula economy,
which ecycles ubbe pieces o c ea e new objec s o o he applica ions. This suppo s he
ele ance o his p ojec o his coun y.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
46
NEUROTRANSMITTER DETECTION WITH GRAPHENE NANOBIOSENSORS
Ma alda Ab an es1, 2, 3, Mohammadmadhi Fa aji1, Jé ôme Bo me1, Luis Jacin o2,
Ped o Alpuim1, 3
1 In e na ional Ibe ian Nano echnology Labo a o y, 4715-330, B aga, Po ugal
2 Expe imen al Biology Uni , Depa men o Biomedicine, Facul y o Medicine, Uni e si y o
Po o, 4200-319 Po o, Po ugal
3 Depa men o Physics, Uni e si y o Minho, 4710-057, B aga, Po ugal
ma alda.ab an [email protected] , mohammadmahdi. a [email protected] , je ome.bo [email protected] , ljacin [email protected] ,
[email p o ec ed]
Keywo ds: G aphene, Nanobiosenso s, Neu al Diseases.
2030 Sus ainable De elopmen Goals: SDG3
Dys unc ions o mul iple neu o ansmi e s' ansmission cause b ain diseases such as
dep ession o schizoph enia. Neu al in e aces, b idging b ain physiology and ex e nal
elec onic de ices, allow b ain unc ion moni o ing o p eclinical esea ch o clinical pu poses.
Despi e ecen ad ances in moni o ing elec ical b ain ac i i y, measu ing chemical
neu o ansmission emains a signi ican challenge. We ha e ecen ly de eloped a pla o m o
obus and ul asensi i e de ec ion o dopamine, an essen ial neu o ansmi e ha unde lies
se e al b ain diso de s, based on g aphene mul i ansis o a ays (gMTAs) unc ionalized wi h
a selec i e DNA ap ame . No only did we achie e he lowes limi -o -de ec ion e e epo ed
(1 aM), bu we could also de ec dopamine wi h g ea sensi i i y in complex samples such as
a i icial ce eb al spinal luid and b ain homogena es, including in a mouse model o
Pa kinson's Disease. He ein, we p esen a no el nanobioelec onic neu al in e ace based on
gMTAs ha allows moni o ing o neu o ansmi e op o-e oked elease in ex i o b ain slices
o ansgenic mice o p eclinical esea ch in neu oscience o pha macology. By op imizing ou
gMTAs' ab ica ion p ocess, we de eloped an in e ace wi h highe senso densi y ha can
accommoda e mice's b ain slices and allows op ogene ic modula ion h ough in eg a ed mic o-
LEDs. The pla o m p esen ed in his wo k can lead he way o no el neu o ansmi e senso s
sui able o eal-wo ld academic and p eclinical pha maceu ical esea ch and clinical
diagnosis.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
47
SUSTAINABLE MATERIALS FOR ANTI-COUNTERFEITING APPLICATIONS
B. D. D. C uz1, 2, *, R. Polícia1, N. Pe ei a1, P. Nunes4, M. Fe nandes4, 5, C. R.
Tubio6, G. Bo elho3, V. de Zea-Be mudez4, 5, S. Lance os-Méndez1, 6, 7, D. M.
Co eia3
1 Physics Cen e o Minho and Po o Uni e si ies (CF-UM-UP) and Labo a o y o Physics o
Ma e ials and Eme gen Technologies (LapMET) Uni e si y o Minho 4710-057 B aga,
Po ugal
2 Cen e o Molecula and En i onmen al Biology, Uni e si y o Minho 4710-057 B aga,
Po ugal
3 Cen e o Chemis y, Uni e si y o Minho, 4710-057 B aga, Po ugal
4 CQ-VR, Uni e si y o T ás-os-Mon es e Al o Dou o,5000-801 Vila Real, Po ugal
5 Chemis y Depa men , Uni e si y o T ás-os-Mon es e Al o Dou o,5000-801 Vila Real,
Po ugal
6 BCMa e ials, Basque Cen e o Ma e ials, Applica ions and Nanos uc u es, UPV/EHU
Science Pa k, 48940 Leioa, Spain
7 Ike basque, Basque Founda ion o Science, 48009 Bilbao, Spain
[email p o ec ed]; dco ei[email p o ec ed]; [email p o ec ed];
[email p o ec ed]; [email p o ec ed]; [email p o ec ed]; [email p o ec ed];
[email p o ec ed]; lance os@ isica.uminho.p ; [email p o ec ed]
Keywo ds: An i-coun e ei ing, Sodium Algina e, Pho oluminescence
2030 Sus ainable De elopmen Goals: SDG5, SDG9, SDG11
Sodium algina e (SA) is a linea polysaccha ide, de i ed om alginic acid, comp ising 1,4-β-d-
mannu onic (M) and α-l-gulu onic (G) acids. The inco po a ion o pho oluminescen
compounds in o he SA ma ix allows he de elopmen o sma ma e ials able o con e
inciden elec omagne ic adia ion o speci ic wa eleng hs (e.g. ul a iole , UV) in o emi ed
elec omagne ic adia ion o di e en egions o he spec a ( isible o in a ed).
In he p esen wo k, pho oluminescen ma e ials based on SA and di e en con en s (5,10 and
20% w .) o he luminescen compound sodium e a(2- henoyl i luo oace ona e) eu opa e (III)
(Na[Eu( a)4]) and 1-bu yl-3-me hylimidazolium e a(2- henoyl i luo oace ona e) eu opa e (III)
([Bmim][Eu( a)4]) we e de eloped by sol en cas ing. FTIR-ATR and DSC analysis showed
ha no ele an changes occu ed in he SA s uc u e upon inco po a ion o he gues
compounds. TGA analysis e ealed a small inc ease o he mal s abili y o he composi es wi h
espec o nea SA. The elec ical conduc i i y o nea SA sligh ly inc eased wi h he
Na[Eu( a)4] con en inc ease. The obse ed dec ease in he Young Modulus is indica i e ha
bo h luminescen compounds ac ed as nuclea ing agen s du ing he SA c ys alliza ion,
inducing a plas icizing e ec in SA. The pho oluminescence p ope ies we e e alua ed and
demons a ing he po en ial o he composi es o an i-coun e ei ing pu poses.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
48
ECO-FRIENDLY LITHIUM-ION BATTERY SEPARATORS BASED ON
CARRAGEENAN BIOPOLYMER FOR SUSTAINABLE ENERGY STORAGE SYSTEMS
João Se a1, Rena o Gonçal es2, Senen xu Lance os-Mendez1, 3, 4, Ca los M.
Cos a1
1 Physics Cen e o Minho and Po o Uni e si ies (CF-UM-UP) and LapMET, Gual a , B aga
2 Cen e o Chemis y o Uni e si y o Minho, Gual a , B aga, Po ugal
3 BCMa e ials-Basque Cen e o Ma e ials, Applica ions and Nanos uc u es, Leioa, Bilbao,
Spain
4 Ike basque-Basque Founda ion o Science, Bilbao, Spain
[email p o ec ed]; [email p o ec ed]; l[email p o ec ed]
[email p o ec ed];
Keywo ds: Ba e y Sepa a o , Ene gy; Na u al Polyme s
2030 Sus ainable De elopmen Goals: SDG7, SDG12, SDG13
Rapid echnological de elopmen s in senso s, ac ua o s and ene gy s o age a eas a e aken place
o ad anced de ices and applica ions. Ene gy s o age sys ems, mainly li hium-ion ba e ies, a e
ex ensi ely applied in elec ic ehicles, sma phones, and lap ops. Mo eo e , hey play a c ucial
ole in eg a ed wi h enewable ene gy sou ces, s o ing su plus ene gy du ing pe iods o excess
p oduc ion and supplying i du ing ene gy de ici s. This app oach aligns wi h he Uni ed Na ions
2030 Agenda's goal o u ilizing sus ainable and enewable ene gy (SDG7) and also mee s SDG 13
- comba clima e change and i s impac s, as hese sys ems allow o he educ ion o dependence
on ossil uels and all he ha m ul consequences ha come om he use o his ype o ene gy
p oduc ion.
Al hough hese sys ems sol e some o he sus ainabili y p oblems, hey ha e o he consequences,
since mos o he ma e ials used in ba e ies de i ed om syn he ic sou ces, o en oo ed in ossil
uels, con ibu ing o cu en en i onmen al pollu ion. Add essing his challenge en ails subs i u ing
syn he ic ma e ials wi h hose o na u al o igin, pa icula ly i sou ced om indus ial was e o
abundan in na u e. Na u al polyme s, de i ed om biological eeds ock, o e no able
en i onmen al ad an ages—such as na u al abundance, enewabili y, biodeg adabili y, and
biocompa ibili y. The use o hese ma e ials mee s he objec i es o he 2030 Agenda in e ms o
ensu ing sus ainable consump ion and p oduc ion pa e ns (SDG12) and comba ing clima e
change (SDG13) o he same easons men ioned p e iously.
This s udy de ails he de elopmen o a lyophilized ca ageenan memb anes wi h a ying polyme ic
concen a ions (1, 2, 3, and 4% w .) o li hium-ion ba e y sepa a o s. In o de o unde s and he
mo phology, physicochemical, he mal and mechanical cha ac e is ics o he ca ageenan
memb anes we e cha ac e ized, and hei elec ochemical cha ac e is ics we e analysed o e i y
hei pe o mance as ba e y sepa a o s.
The elec ochemical cha ac e is ics o he memb anes a e in luenced by he ca ageenan polyme
concen a ion. Wi h 4 w % ca ageenan, he memb anes exhibi ionic conduc i i y, o uosi y,
MacMullin numbe , and li hium ans e ence numbe o 1.34 mS cm-1, 3, 7, and 0.48, espec i ely.
Hal -cells ca hodic assemblies wi h hese memb anes demons a e obus cyclabili y and a e
capabili y. The discha ge capaci y alues a C/10- and 1C- a es a e 145 and 25 mAh g-1,
espec i ely, showcasing ou s anding cycling pe o mance and long- e m s abili y.
This s udy highligh s he po en ial o io a-ca ageenan biopolyme memb anes, de eloped h ough
eeze-d ying, as sepa a o s o he nex gene a ion o sus ainable ba e ies.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
49
LOCALIZED SURFACE PLASMON RESONANCE (LSPR) SENSORS BASED ON
SPUTTERED NANOPLASMONIC THIN FILMS
Diana I. Mei a, Joel Bo ges, Filipe Vaz
Physics Cen e o Minho and Po o Uni e si ies (CF-UM-UP), Uni e si y o Minho, Campus
de Azu ém, 4800-058 Guima ães, Po ugal
[email p o ec ed]
Keywo ds: Nano echnology, Sensing, Nanoplasmonic hin ilms
2030 Sus ainable De elopmen Goals: SDG2, SDG3, SDG12
The ield o nano echnology, wi h i s e olu iona y inno a ions, p esen s many solu ions o
add ess and ul il cu en global demands. Among i s mos no able ad ancemen s is he
de elopmen o Localized Su ace Plasmon Resonance (LSPR) senso s, a cu ing-edge
applica ion o nano echnology ha is changing he landscape o sensi i e de ec ion
mechanisms. The LSPR e ec a ises om he exci a ion o localized su ace plasmons on he
me allic nanopa icle’s su ace. This e ec is pa icula ly obse ed in nanoplasmonic hin ilms,
which consis o me allic nanopa icles (gold o sil e ) embedded in a ious dielec ic ma ices
(oxide o ni a e). Due o hei unique op ical p ope ies, hese ilms can be used as sui able
label- ee and highly sensi i e op ical ansduce s. A e deposi ing he nanoplasmonic hin
ilms h ough eac i e di ec cu en magne on spu e ing, pos -deposi ion hea ea men s a
a ious empe a u es a e employed o induce he g ow h o he nanopa icles and enhance
hei plasmonic beha io . To e alua e he ilms' pe o mance as LSPR senso s, hey a e
exposed o ex e nal s imuli ha modi y he e ac i e indices o hei adjacen media. These
al e a ions in e ac i e indices di ec ly impac he plasmonic beha io (LSPR band) o he
plasmonic ilms, which a e me iculously moni o ed using a high- esolu ion LSPR spec oscopy
sys em. Beyond he sensi i i y, selec i i y is a c i ical ea u e in LSPR senso echnology. This
selec i i y can be achie ed h ough di e en immobiliza ion p ocesses by a aching speci ic
binding elemen s (i.e., p o eins, ap ame s, and an ibodies) o he su ace o he hin ilms. In a
p oo -o -concep expe imen , a bio ecogni ion laye was immobilized on he su ace o Au-TiO2
hin ilms, p o iding a ge analy e speci ici y. S ep a idin and bio in we e he bio ecep o -
analy e model chosen o p o e he immobiliza ion e iciency and o demons a e he LSPR
senso po en ial. The chemical in e ac ion be ween he aimed a ge was con i med by an
LSPR wa eleng h shi , sugges ing success ul de ec ion. Essen ially, he main ad an age o
he LSPR senso , using nanoplasmonic hin ilms, is i s e sa ili y since i s undamen al
p inciples can be applied adap i ely o a wide ange o a ge s, unde lining i s b oad po en ial
in ad anced de ec ion applica ions.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
50
3D-PRINTED MULTILAYER MEMBRANES FOR PHOTOCATALYTIC DEGRADATION
OF CIPROFLOXACIN
Dinis. C. Al es1, 2, P.M. Ma ins2, 3, D.M. Co eia4, S. Lance os-Méndez2, 5, 6
1 Cen e/Depa men o Physics, Uni e si y o Minho, 4710-057 B aga, Po ugal
2 IB-S – Ins i u e o Resea ch and Inno a ion on Bio-Sus ainabili y, Uni e si y o Minho 4710-
057 B aga, Po ugal
3 Cen e o Molecula and En i onmen al Biology, Gual a , B aga
4 Cen e o Chemis y, Uni e si y o Minho, 4710-057 B aga, Po ugal
5 BCMa e ials, Basque Cen e o Ma e ials, Applica ions and Nanos uc u es, UPV/EHU
Science Pa k, 48940 Leioa, Spain
6 Ike basque, Basque Founda ion o Science, 48009 Bilbao, Spain
[email p o ec ed].p , [email p o ec ed]; [email p o ec ed];
lance os@ isica.uminho.p
Keywo ds: 3D-p in ing, Memb anes, Pho oca alysis
2030 Sus ainable De elopmen Goals: SDG6, SDG7, SDG12
The s ong echnological de elopmen and high popula ion g ow h ha e gene a ed inc eased
pollu an s eleased in o he en i onmen . These pollu an s, also called eme ging pollu an s,
a e ound in p oduc s used in e e yday li e. They a e esilien and e y s able in he
en i onmen , making cu en con en ional wa e ea men me hods ine ec i e o hei
emo al. New echnological concep s based on pho oca aly ic memb anes ha e p o en
e ec i e in emo ing hese con aminan s. This wo k ocuses on he p oduc ion,
cha ac e iza ion and applica ion o mul ilaye pho oca aly ic memb anes p oduced by addi i e
manu ac u ing. The echnique used in his wo k was di ec ink w i ing (DIW), es ing he
in luence o a ious p in ing pa ame e s, such as he p in ing mul iplie and in ill. This echnique
allows he p oduc ion o mul ilaye memb anes wi h high ep oducibili y, con ols hei shape
and mo phology and educes ma e ial was e. Thus, TiO2 nanopa icles we e immobilized in a
luo ide-co-hexa luo op opylene poly inylidene (PVDF-HFP) and sodium chlo ide (NaCl)
solu ion. A laye o his solu ion was p in ed on a glass subs a e ollowed by a he mal cycle
o 30 minu es a 120oC o sol en e apo a ion and c ys alliza ion o he polyme , hen a second
laye was p in ed unde he p e iously p in ed one and he he mal cycle was epea ed. The
ma e ials we e cha ac e ized, and hei e iciency in cip o loxacin pho oca aly ic deg ada ion
was es ed. The mul ilaye memb ane exhibi ed a highly po ous s uc u e and hyd ophilic
beha iou , ob aining posi i e esul s in he a ious pho oca aly ic es s pe o med, wi h up o
44% e iciencies in he deg ada ion o cip o loxacin (2.5 mg/L) unde ul a iole adia ion o
240 minu es, con i ming ema kable esul s in eu iliza ion. These esul s alida e he c ea ion
o memb anes o en i onmen al emedia ion by addi i e manu ac u ing.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
51
ATTOMOLAR SENSING OF MUTATED BRAIN TUMOR DNA USING
ELECTROLYTE-GATE GRAPHENE TRANSISTORS
Telma Domingues1,2, Jé ôme Bo me2, B uno M. Cos a3, Ped o Alpuim1, 2
1 Depa men o Physics, Uni e si y o Minho, 4710-057, B aga, Po ugal
2 In e na ional Ibe ian Nano echnology Labo a o y, 4715-330, B aga, Po ugal
3 Li e and Heal h Sciences Resea ch Ins i u e (ICVS), School o Medicine, Uni e si y o
Minho, 4710-057, B aga, Po ugal
elma.doming[email p o ec ed]; je ome.bo [email protected] ; b mcos [email protected] ; ped o.alpuim[email p o ec ed]
Keywo ds: Ci cula ing Tumo DNA, G aphene T ansis o s, Ea ly De ec ion
2030 Sus ainable De elopmen Goals: SDG3
Malignan gliomas a e he mos common p ima y b ain umo s in he cen al ne ous sys em,
wi h e y high mo bidi y and mo ali y. Glioblas oma is he mos common and malignan
sub ype o glioma in adul s, and e en wi h op imal ea men , he median su i al ime is only
12-15 mon hs. De ec ion me hods a e expensi e and in asi e o pa ien s and e ec i e only
when he disease is al eady in ad anced s ages. Recen ly, ea ly b ain umo diagnosis by
de ec ing ace amoun s o ci cula ing umo DNA in liquid biopsies was demons a ed. This
inding could be a game change in he igh agains b ain cance i new e sa ile biosensing
echnology is a ailable.
This wo k de elops a no el g aphene liquid-ga e ansis o wi h an unp eceden ed low limi o
de ec ion. The signal comes om he local ga ing o he g aphene ansis o channel, di ec ly
exposed o he analy e in solu ion. The speci ici y o he a ge s ems om g aphene
unc ionaliza ion wi h syn he ic DNA immobilized by non-co alen chemis y. The g aphene
elec oly e ga ed ield-e ec ansis o (EG-gFET) chip was in eg a ed wi h a minia u ized
A duino-compa ible eade ha p o ides an easy and “wi hin-seconds” ou e owa d DNA
de ec ion. A small amoun o mu a ed syn he ic DNA is mixed wi h a la ge amoun o heal hy
DNA in a p opo ion simila o he expec ed occu ence in clinical samples, e.g., 0.1:100, 1:100,
and 10:100. The senso s show sensi i i y o he de ec ion o he mu a ed DNA e en hough i
di e s only by one base (single-nucleo ide polymo phism) om he unmu a ed sequence. The
lowes mu a ed DNA de ec ion le el was in he em omola ange. Expe imen s we e
pe o med in syn he ic phospha e bu e , spiked undilu ed human plasma, and dilu ed bu e .
Wi h an inc ease o dilu ion om 1× o 100×, a e e sal o he ou pu signal, om nega i e o
posi i e, is obse ed. A plasma dilu ion o 25× enabled bio-sensing esul s simila o hose in
an a i icial bu e .
These indings deno e he po en ial o g aphene ield-e ec ansis o s o he eco d-low le el
o de ec ion o ci cula ing umo DNA in a complex ma ix equi ed o u u e clinical use.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
52
INVESTIGATING FLUORINATED POLYMER MATRICES' IMPACT ON SOLID
POLYMER ELECTROLYTE PERFORMANCE WITH IONIC LIQUIDS FOR ADVANCED
SOLID-STATE LITHIUM-ION BATTERIES
Ra ael Pin o1, 2, João Ba bosa1, 2, Daniela Co eia2, Ma ia Sil a2, Rena o
Gonçal es2, Senen xu Lance os-Mendez1, 3, 4, Ca los Cos a1, 5
1 Physics Cen e o Minho and Po o Uni e si ies (CF-UM-UP) and Labo a o y o Physics o
Ma e ials and Eme gen Technologies, LapMET, Uni e si y o Minho, 4710-057 B aga,
Po ugal
2 Cen e o Chemis y, Uni e si y o Minho, 4710-057 B aga, Po ugal
3 BCMa e ials, Basque Cen e o Ma e ials, Applica ions and Nanos uc u es, UPV/EHU
Science Pa k, 48940 Leioa, Spain
4 Ike basque, Basque Founda ion o Science, 48009 Bilbao, Spain
5 Ins i u e o Science and Inno a ion o Bio-Sus ainabili y (IB-S), Uni e si y o Minho, 4710-
057 B aga, Po ugal
[email protected] , joaocpba bosa@li e.com.p , danielamsco [email protected],
[email p o ec ed], [email p o ec ed], [email p o ec ed],
[email p o ec ed]
Keywo ds: Ionic liquids, Solid polyme elec oly e, Solid-s a e ba e ies
2030 Sus ainable De elopmen Goals: SDG7, SDG13
This wo k epo s on he e ec o he polyme chain pola i y, deg ee o c ys allini y and
dielec ic cons an on he elec ochemical p ope ies and ba e y pe o mance o solid polyme
elec oly es. Solid polyme elec oly es (SPEs) we e p oduced using di e en luo ina ed
polyme ma ices, including poly( inylidene- luo ide), PVDF, poly( inylidene luo ide-co-
hexa luo op opylene) - P(VDF-HFP), poly( inylidene luo ide-co- i luo oe hylene) - P(VDF-
T FE) and poly( inylidene luo ide-co- i luo oe hylene-chlo o luo oe hylene) - P(VDF-T FE-
CFE) illed wi h an ionic liquid (IL) (1-Me hyl-1-p opylpy olidinium
bis( i luo ome hylsul onyl)imide – [PMPy ][TFSI]). I is p o en ha he use o he di e en
polyme s does no signi ican ly a ec he he mal p ope ies and mo phology o he SPEs.
Howe e , ega ding mechanical p ope ies and deg ee o c ys allini y, hey show lowe alues
o he P(VDF-T FE-CFE) sample. Conce ning elec ochemical pa ame e s, all samples
p esen ionic conduc i i y and li hium ans e ence numbe alues sui able o li hium-ion
ba e y (LIB) applica ions, wi h emphasis in he P(VDF-HFP) sample, showing a oom
empe a u e ionic conduc i i y o 6.2 x 10-5 S.cm-1 and a li hium ans e ence numbe o 0.71,
o P(VDF-T FE-CFE), associa ed o a lowe deg ee o c ys allini y and a high dielec ic
cons an . Rega ding ba e y cycling assessmen s, P(VDF-T FE) shows, unde oom
empe a u e and C/10 a e, a maximum discha ge alue o 146 mAh.g-1. Mo eo e , he P(VDF-
T FE-CFE) sample exhibi s ou s anding cycling pe o mance a ele a ed discha ge a es,
a aining 91 mAh.g-1 a 1C a e, while main aining ema kable s abili y a e 60 cycles, unde
oom empe a u e condi ions. This highligh s i s conside able po en ial o u iliza ion in LIBs,
a ibu ed o i s low c ys allini y and ele a ed dielec ic cons an . Conside ing he
a o emen ioned ac s, i is p o en he sui abili y o luo ina ed polyme s o SPEs de elopmen
when allied o an IL ac i e ille o a nex gene a ion o solid-s a e ba e ies. Addi ionally, i
o e s impo an insigh s in o he in luence o he polyme ’s dielec ic cons an and deg ee o
c ys allini y on ba e y pe o mance.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
53
CENTRO DE INVESTIGAÇÃO EM ENFERMAGEM
RESEARCH CENTER OF NURSING
CIENF
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
54
COST- EFFECTIVENESS OF A HEALTH PROMOTION PROGRAM IN PRIMARY
SCHOOLS AND CHILDREN IN SOCIALLY VULNERABLE CONDITIONS - CLUSTER-
RANDOMIZED STUDY (BEE-SCHOOL)
Juliana Ma ins1, 2, 3, 10, Cláudia Augus o1, 2, 3, Ma ia José Sil a1, 2, Ana Dua e1, 2,
3,-4, Sil ana Ma ins2, 5, Henedina An unes6, 7, Paulo No ais8, Bea iz Pe ei a4, 9,
Paula Veiga10, 11, Ra aela Rosá io1, 2, 3, 4
1 School o Nu sing, Uni e si y o Minho, B aga
2 UICISA:E,The Heal h Sciences Resea ch Uni : Nu sing, School o Nu sing o Coimb a,
Coimb a
3 CIENF: Resea ch Cen e o Nu sing, B aga
4 CIEC: Resea ch Cen e o Child S udies, Uni e si y o Minho, B aga
5 P oChild CoLAB Agains Po e y and Social Exclusion – Associa ion, Guima ães
6 Unidade Local de Saúde de B aga e Cen o Clínico Académico, B aga
7 ICVS: Li e and Heal h Sciences Resea ch Ins i u e; ICVS/3B's Associa e Labo a o y;
School o Medicine, Uni e si y o Minho, B aga
8 ALGORITMI Resea ch Cen e , Depa men o In o ma ics, School o Enginee ing, Uni e si y
o Minho, B aga
9 Ins i u e o Educa ion, Uni e si y o Minho, B aga
10 School o Economics and Managemen , Uni e si y o Minho, B aga
11 JusGo : Resea ch Cen e on Jus ice and Go e nance, Uni e si y o Minho, B aga
[email p o ec ed]; coli ei[email p o ec ed]; mjsil[email p o ec ed];
[email p o ec ed]; sil ana.ma [email p o ec ed]; [email p o ec ed];
[email p o ec ed]; bea [email p o ec ed]; [email p o ec ed]; [email p o ec ed]
Keywo ds: Child, Obesi y, Cos -e ec i eness
2030 Sus ainable De elopmen Goals: SDG3, SDG4, SDG10
Objec i e: The goal o his s udy is o e alua e he cos -e ec i eness o he heal h p omo ion
p og am (BeE-school) conce ning he Body Mass Index (BMI) z-sco e in child en a ending
p ima y schools acing ulne able condi ions.
Me hods: The BeE-school s udy in ol ed 735 child en (51.7% boys, a e age age 7.7 yea s
old) om 10 p ima y schools in he No he n egion o Po ugal. These schools we e pa o
wo school g oups iden i ied as Educa ional Te i o ies o P io i y In e en ion. A e he ini ial
assessmen , he schools we e andomized in o wo g oups: one ecei ing he in e en ion (4
schools) and he o he no (6 schools). The in e en ion included educa ing and aining
eache s o 16 weeks, hei implemen a ion in he class oom, and gi ing amilies challenges
e e y wo weeks. To assess he p og am’s e ec i eness, we measu ed he child en's weigh
and heigh using s anda dized me hods. Then we calcula ed hei BMI and used he Wo ld
Heal h O ganiza ion LMS o compu e hei BMI z-sco e (BMIz). We analyzed he da a wi h IBM
SPSS V.28, se ing ou signi icance le el a 5%. The p ima y ou come was he di e ence in
BMIz om baseline o pos -in e en ion. We used Gene alized Linea Model conside ing he
ou come as he di e ence in BMIz om baseline o pos -in e en ion and he p edic o as g oup
alloca ion (con ol/in e en ion). We also adjus ed o school g oups, school le el, leng h o
ime om baseline o pos -in e en ion assessmen , sex, age, and mo he s’ and a he s’
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
61
CENTRO DE INVESTIGAÇÃO EM PSICOLOGIA
PSYCHOLOGY RESEARCH CENTER
CIPsi
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
62
EFFECTIVENESS OF THE SHORT MOTIVATIONAL PROGRAMME: A RANDOMIZED
CONTROL TRIAL
Te esa Sil a1, Olga Cunha2, Sónia Ca idade1
1 Psychology Resea ch Cen e (CIPsi), Uni e si y o Minho, B aga
2 HEI-Lab: Digi al Human-En i onmen In e ac ion Labs, Lusó ona Uni e si y, Po o
[email protected] ; [email protected] ; sca [email protected]
Keywo ds: Sho Mo i a ional P og amme; Mo i a ional In e iewing; Fo ensic con ex .
2030 Sus ainable De elopmen Goals: SDG3, SDG5
Mo i a ional In e iewing (MI) has p o en o be a c ucial ool in educing o ending beha iou ,
p e en ing ecidi ism, and ein eg a ing indi iduals in o socie y by enhancing he e ec i eness
o in e en ion p og ams wi h a heigh ened ocus on he needs o each pe son. The aim o his
s udy is o adap and cul u ally alida e he Sho Mo i a ional P og amme (SMP), and o
implemen and assess i s e ec i eness in e ms o bo h p ocess and ou come (i.e. clinical
change and in e -g oup and in a-subjec change) among indi iduals sen enced o cus odial
and non-cus odial measu es using a andomised con olled ial (RCT). Six y indi iduals (30
emale and 30 male) will be sc eened o eligibili y and assigned o one o ou condi ions: 1)
indi iduals in p ison ecei ing in e en ion; 2) indi iduals in p ison wi hou in e en ion; 3)
indi iduals in he communi y ecei ing in e en ion; and 4) indi iduals in he communi y wi hou
in e en ion. Pa icipan s will comple e ins umen s assessing mo i a ion o change,
c iminogenic belie s, and blame a ibu ion in ou momen s: baseline, pos - ea men , 3-mon h
ollow-up, and 6-mon h ollow-up. Upon comple ion o he p og am, a inal assessmen will be
conduc ed o assess he quali y and in eg i y o he implemen a ion o he SMP and he
psychologis 's pe o mance. This e alua ion will be conduc ed using he Mo i a ional
In e iewing T ea men In eg i y (MITI 4.2.1), a quali a i e me hodology measu ing he ideli y
and quali y o MI. Conside ing p e ious s udies (e.g., Aus in e al., 2011), i is an icipa ed ha
he SMP will exhibi signi ican changes in a iables such as mo i a ion o change, a ibu ion
o guil o he c ime, commi men o he in e en ion, ecidi ism, and d opou . Th ough his
s udy, we aim o con ibu e o a deepe scien i ic unde s anding o he impac o MI in he
o ensic con ex , acili a ing he in eg a ion o mechanisms o suppo in e en ions wi h
pe pe a o s. The ul ima e goal o hese mechanisms is o enhance ein eg a ion and p e en
ecidi ism in Po ugal.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
63
EMPATHY AND EXECUTIVE FUNCTIONING IN INCARCERATED WOMEN:
COMPARATIVE ANALYSIS BETWEEN VIOLENT AND NON-VIOLENT CRIMES
Ana Bea iz Machado1, Ma ina Pinhei o1, Sónia Ca idade1, Olga Cunha2
1Psychology Resea ch Cen e (CIPsi), School o Psychology, Uni e si y o Minho, Azu ém, B aga
2School o Psychology, Uni e si y o Minho; Lusó ona Uni e si y, Hei-Lab
[email p o ec ed]; [email p o ec ed].p ; [email p o ec ed];
[email p o ec ed]
Keywo ds: Female C iminali y, Empa hy, Execu i e Func ioning
2030 Sus ainable De elopmen Goals: SDG5.
The lack o empa hy and de ici s in execu i e unc ioning a e o en ela ed o an isocial
beha io which may inc ease he likelihood o in ol emen and pe pe a ion o c iminal ac s.
In he Po uguese con ex , scien i ic esea ch ocused on he phenomena o emale c iminali y
has been neglec ed o e he yea s, wi h only a small numbe o s udies dedica ed o he s udy
o how empa hy and execu i e unc ioning ela e o ha ma e .
The e o e, he p esen s udy aims o analyze empa hy and execu i e unc ioning in
inca ce a ed women who commi ed iolen and non- iolen c imes.
The esea ch is expec ed o in ol e 102 emale pa icipan s om di e en p ison acili ies in
Po ugal. The pa icipan s we e asked o comple e a su ey ha sough in o ma ion on hei
sociodemog aphic and sociolegal backg ounds, he Basic Empa hy Scale, and he F on al
Assessmen Ba e y.
Based on p io esea ch, he ollowing esea ch hypo heses can be de eloped: women who
a e inca ce a ed end o ha e lowe le els o empa hy and g ea e de ici s in execu i e
unc ioning; inca ce a ed women who ha e commi ed iolen c imes exhibi simila le els o
empa hy as hose who ha e commi ed non- iolen c imes; inca ce a ed women who
commi ed iolen c imes end o demons a e highe de ici s in execu i e unc ioning
compa ed o non- iolen o ende s. Addi ionally, he e appea s o be a posi i e co ela ion
be ween empa hy and execu i e unc ioning in inca ce a ed women.
This s udy aims o p o ide in o ma ion on he unc ioning o women who commi ed c imes in
Po ugal, along wi h i s unde lying mechanisms. I also hopes o educe some o he
disc epancies ha exis be ween esea ch conduc ed on men and women. In summa y, he
s udy aims o shed mo e ligh on he na u e o emale c iminali y in Po ugal.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
64
“A RAINBOW SCHOOL PROGRAM”: DEVELOPMENT AND ASSESSMENT OF AN
INTERVENTION WITH EDUCATIONAL AGENTS TO PREVENT VICTIMIZATION OF
LGBTQ STUDENTS
Ma lene Fe ei a1, Sónia Ca idade1, Ca la Fon e 2
1 Resea ch Cen e on Psychology (CIPsi), Uni e si y o Minho, B aga, Po ugal
2 Resea ch, Inno a ion and De elopmen Ins i u e”, Uni e sidade Fe nando Pessoa, Po o,
Po ugal
[email protected] , sca [email protected] , [email p o ec ed]du.p
Keywo ds: In e en ion p og am; Educa ional Agen s; LGBTQ S uden s
2030 Sus ainable De elopmen Goals: SDG3, SDG4, SDG16
The LGBTQIA+ popula ion aces daily challenges, which impac social, wo k and school
inclusion. LGBTQIA+ s uden s expe ience high le els o ic imiza ion, gene a ing eelings o
insecu i y, poo academic pe o mance and high a es o school absen eeism, eeling
unp o ec ed and li le unde s ood by educa ional agen s (EA).
Al hough mos o hese abusi e beha io s and disc imina ion a e ca ied ou by pee s, EA can
also disc imina e agains LGBTQIA+ s uden s, by e ealing unp epa edness o deal wi h
heme on daily basis, due o lack o skills, awa eness, needs and challenges o his popula ion.
Causing a ba ie o social inclusion and e ic imiza ion o hese s uden s.
The p esen s udy aims o de elop and es he e ec i eness o a g oup psychological
in e en ion p og am, oge he wi h EA, o p omo e school inclusion as a ic imiza ion
p e en ion s a egy. The cons uc ion o i , will be based on he li e a u e, using a sys ema ic
e iew and a me a-analysis. A ocus g oup will also be held wi h expe s and pa ne en i ies,
wi h aim on unde s anding he main p oblems and needs o he LGBTQIA+ popula ion. A
li e acy scale on school inclusion o he LGBTQIA+ popula ion will also be cons uc ed, which
allows unde s anding he li e acy le el o EA in ela ion o he school inclusion o LGBTQIA+
s uden s, iden i ying he main needs o be me wi h he implemen a ion o he in e en ion
p og am.
This is a longi udinal s udy, wi h a quasi-expe imen al design, and will ea u e p e and pos
in e en ion assessmen , using an assessmen p o ocol ha in eg a es quan i a i e
measu emen ins umen s and semi-s uc u ed in e iews. We es ima ed ha he ollow-up will
be ca ied ou be ween 6-8 mon hs a e implemen ing he p og am, allowing us o unde s and
he s abili y o he esul s o e ime.
I is expec ed ha pa icipan s will be able o unde s and he beha io s, ulne abili ies, ea s
and weaknesses o LGBTQIA+ s uden s, adop ing mo e e ec i e in e en ion s a egies,
capable o minimizing he isk o ic imiza ion in his popula ion on school con ex , p omo ing
a highe le el o li e acy in school inclusion o LGBTQIA+ s uden s.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
65
DEVELOPMENT AND EFFECTIVENESS ASSESSMENT OF AN INTERVENTION FOR
INTERNET CHILD SEX OFFENDERS USING A RANDOMIZED CONTROL TRIAL
Cláudia Gou eia1, Olga Cunha2, Michael Se o3, Sónia Ca idade1
1 Resea ch Cen e on Psychology (CIPsi), Uni e si y o Minho, B aga, Po ugal
2 HEI-Lab: Digi al Human-En i onmen In e ac ion Labs, Lusó ona Uni e si y, Po o, Po ugal
3 Royal O awa Heal h Ca e G oup, B ock ille, On a io, Canada
[email protected] , [email protected] , michael.se o@ he oyal.ca,
[email p o ec ed].
Keywo ds: Online Sexual O ending, In e en ion P og am, Randomized Con ol T ial
2030Sus ainable De elopmen Goals: SDG4, SDG16
In e ne -child sex o ende s (I-CSO) a e a cause o public conce n due o he nega i e impac
hey ha e on hei ic ims, he sense o insecu i y hey ins il in he communi y, and he inc ease
in he demand o child po nog aphy ha hey con ibu e o. As hese beha io s become mo e
p e alen , he e is a p essing need o he de elopmen o in e en ion p og ams ailo ed o
he needs and cha ac e is ics o I-CSO.
In he Po uguese con ex , o bes o ou knowledge, he e a e no speci ic in e en ions
a ge ing I-CSO. Resea ch on he cha ac e is ics o I-CSO sugges s ha hey di e in many
ways om o he child sex o ende s, indica ing a di e en isk o ecidi ism. Consequen ly,
in e en ions should be designed based on hese di e ences and speci ici ies.
This s udy aims o design and implemen an in e en ion p o ocol o I-CSO se ing communi y
and p ison sen ences, and o e alua e i s e ec i eness in e ms o bo h p ocess and ou come.
The in e en ion p og am's de elopmen will be in o med by a e iew o li e a u e, iden i ying
echniques deemed mos e ec i e wi h he I-CSO popula ion. Subsequen ly, a popula ion
cha ac e iza ion s udy will be conduc ed o pinpoin he speci ic c iminogenic needs o he
Po uguese I-CSO, guiding in e en ion objec i es based on specialized esea ch and
in eg a ing p o en heo e ical models.
The p og am will encompass indi idual and g oup componen s, add essing c iminogenic
needs and accommoda ing di e se lea ning s yles. A andomized clinical ial, adop ing a
longi udinal design, will inco po a e p e/pos -in e en ion assessmen s and ollow-ups a 3 and
6 mon hs, wi h in e en ion and con ol g oups in bo h communi y and p ison se ings. We
expec o ha e eigh g oups wi h 6-8 indi iduals each, wo in e en ion g oups and wo con ol
g oups o I-CSO se ing p ison sen ences, and wo in e en ion g oups and wo con ol g oups
se ing communi y sen ences. E alua ion will also include pa icipan eedback and egula
p og am assessmen s.
Addi ionally, semi-s uc u ed in e iews wi h p og am comple e s will p o ide deepe insigh s
in o he in e en ion and he p ocess o change. This in eg a ed app oach aims o align s udy
objec i es wi h me hods allowing a comp ehensi e analysis o he in e en ion p o ocol's
e ec i eness, add essing he speci ic needs o I-CSO in bo h communi y and p ison se ings.
We expec o educe he isk ac o s, equip o ende s wi h in o ma ion and skills o o e come
hei beha io s, and educe he isk o ecidi ism. Fu he mo e, he p og am seeks o p o ec
child en by lowe ing he likelihood o hem alling ic im o sex c imes, a c i ical conce n gi en
hei ulne abili y.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
66
DARK TRIAD, SEXTING, AND ONLINE GROOMING: MALEVOLENT SIDE OF
ONLINE SEXUAL ACTIVITY IN YOUNG ADULTS
Ma iana F. Cos a, Sónia Ca idade
Psychology Resea ch Cen e (CIPsi), School o Psychology, Uni e si y o Minho, Gual a ,
B aga
[email p o ec ed]; [email p o ec ed]
Keywo ds: Sex ing, Online g ooming, Da k T iad
2030 Sus ainable De elopmen Goals: SDG3, SDG16
Young adul s equen ly engage in Online Sexual Ac i i ies (OSA) h ough In o ma ion and
Communica ion Technologies (ICT) o main ain in ima e ela ionships and explo e hei
sexuali y. OSA encompasses ac i i ies such as sex ing and online g ooming, and he
p e alence o hese beha io s has su ged wi h he widesp ead adop ion o ICT in in e pe sonal
communica ion. While he link be ween pe sonali y ai s and OSA is well-es ablished, scan
a en ion has been gi en o he associa ion be ween he Da k T iad pe sonali y ai s and
sex ing and online g ooming beha io s. Exis ing li e a u e indica es posi i e co ela ions
be ween he Da k T iad ai s and sex ing, wi h highe le els o sex ing se ing as a p edic o
o g ooming. Fu he mo e, he e is a no able absence o alida ed ins umen s o assessing
hese phenomena wi hin he Po uguese popula ion.
The e o e, he main objec i e o his s udy is o cha ac e ize he p e alence o sex ing and
online g ooming among young Po uguese adul s and examine hei po en ial associa ion wi h
pe sonali y ai s. Speci ically, his s udy aims o: i) alida e and desc ibe he psychome ic
cha ac e is ics o The Sex ing Scale and The G ooming Scale o he Po uguese popula ion;
ii) explo e he ela ionship be ween sex ing expe ience and Da k T iad pe sonali y
cha ac e is ics; iii) explo e he ela ionship be ween online g ooming expe ience and Da k
T iad pe sonali y cha ac e is ics.
Conduc ed as an explo a o y c oss-sec ional s udy wi h a quan i a i e app oach, he sample
will consis o 260 pa icipan s aged 18 o 25 yea s. Based on exis ing li e a u e, i is an icipa ed
ha The Sex ing Scale and The G ooming Scale ins umen s will demons a e sa is ac o y
in e nal consis ency and di e gen and con e gen alidi y. High le els o sex ing a e expec ed
o be associa ed wi h online g ooming, and bo h high le els o Da k T iad ai s and online
g ooming expe iences a e expec ed o be linked wi h sex ing.
This s udy aims o con ibu e aluable insigh s in o he p e alence o sex ing and online
g ooming among young adul s in Po ugal, in o ming p e en i e and in e en ion s a egies
add essing in e ne - ela ed isks. Addi ionally, i is hoped ha his esea ch will encou age
u he in es iga ions in o hese phenomena wi hin he Po uguese con ex .
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
67
SOCIAL INTEGRATION SKILLS DURING IMPRISONMENT: A LONGITUDINAL
STUDY
Ana Filipa Mou ão1, Olga Cunha2, Leonel Gonçal es3, Sónia Ca idade1
1 Psychology Resea ch Cen e (CIPsi), Uni e si y o Minho, B aga, Po ugal
2 HEI-Lab: Digi al Human-En i onmen In e ac ion Labs, Lusó ona Uni e si y, Po o, Po ugal
3 Gene a Uni e si y Hospi als, Di ision o P ison Heal h, Gene a, Swi ze land
3 Uni e si y o Be n, Ins i u e o P ima y Heal h Ca e (BIHAM), Be n, Swi ze land
[email protected] ; olga.cunha@uluso ona.p ; [email protected];
[email p o ec ed]
Keywo ds: P ison, De ained pe sons, Rein eg a ion, Rehabili a ion, Risk and P o ec i e
Fac o s, Longi udinal S udy
While nume ous s udies ha e ocused on ecidi ism (o i s absence) as he p ima y measu e
o success ul communi y ein eg a ion, i is impo an o b oaden his pe spec i e.
This s udy aims o e alua e he social in eg a ion capabili ies o indi iduals upon en e ing he
open egime ( acing he in e io o ex e io ), as well as 6 and 12 mon hs a e en e ing he open
egime. We will also seek o include an assessmen a e elease om p ison. We in end o
collec da a om 100 males aged 18 o o e . Se e al psychome ic ins umen s will be used,
including a measu e o social in eg a ion as he dependen a iable, measu es o c iminogenic
ac o s, physical and men al heal h, coping s a egies, iolence, and c ime as independen
a iables. The independen a iables will only be adminis e ed a he i s assessmen momen .
The assessmen a e elease om p ison will be conduc ed by sending he social in eg a ion
measu e o pa icipan s by pos o email, o h ough elephone ques ioning.
This app oach will allow o an upda e o knowledge on impo an indica o s in he p ocess o
ansi ioning om p ison o socie y, no limi ed o ecidi ism. Fu he mo e, we will be able o
assess whe he he Po uguese p ison sys em helps indi iduals o de elop hei social
in eg a ion and iden i y he ac o s necessa y o de eloping hese skills. Ou esea ch may
p o ide aluable insigh s ha can guide co ec ional policies and, ul ima ely, p omo e he
ehabili a ion o de ained pe sons.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
68
ONLINE GROOMING OF CHILDREN: PREVALENCE AND IMPACT
Joana A aújo1, Sónia Ca idade1, Ana Isabel Sani2, Celina Mani a3
1 Psychology -Resea ch Cen e (CIPsi), Uni e si y o Minho, B aga, Po ugal
2 Child S udies Resea ch Cen e (CIEC), B aga, Uni e si y Fe nando Pessoa, Po o,
Po ugal. Po ugal.
3 Cen e o De ian Beha iou Sciences (FPCEUP), Facul y o Psychology and Educa ional
Sciences o he Uni e si y o Po o (FPCEUP), Po o, Po ugal.
[email protected] ; sca[email p o ec ed]minho.p ; [email p o ec ed]; [email p o ec ed]
Keywo ds: Online g ooming, child, p e alence, impac
2030 Sus ainable De elopmen Goals: SDG3, SDG4, SDG16
G ooming is a p emedi a ed beha io aimed a en icing, ypically, unde age ic ims wi h a
speci ic goal. Online g ooming is unde s ood as he sexual en icemen o mino s, a p ocess
h ough which he o ende p epa es he child by gaining hei us , wi h he aim o ob aining
con en , main aining con ac , o de eloping sexual in e ac ions, wi h o wi hou physical
con ac , ei he di ec ly o ia he in e ne , while keeping i a sec e . Despi e being a conce n in
in e na ional s udies, i is ela i ely unknown in he Po uguese con ex . Online sexual iolence
agains mino s has been on he ise o e he yea s, d i en by he inc easing challenges and
isks o he in e ne and/o social ne wo ks. In 2016, an explo a o y s udy in Po ugal e ealed
a 20.5% ic imiza ion a e due o online g ooming. The Po uguese Associa ion o Vic im
Suppo (APAV) epo om 2016 o 2020 indica es ha he solici a ion o mino s o sexual
pu poses ep esen s 2.9% o epo ed cases. In Po ugal, online g ooming emains a mys e y
o he majo i y o child en and a phenomenon ela i ely o e looked by he scien i ic communi y
and socie y a la ge.
Howe e , esea ch on his issue and i s impac , especially exis ing suppo esponses, is
sca ce. The e o e, his s udy aims o adap and alida e an ins umen o he Po uguese
popula ion asce ain he p e alence in child en aged 12 o 18 who a e ic ims o online
g ooming and impac o his ype o ic imiza ion, as well as he cha ac e is ics o ic ims and
o ende s.
These indings open possible di ec ions o esea ch on he cha ac e is ics and consequences
o online g ooming
I is es ima ed ha he esul s o mul i a ia e and con en analyses will indica e e ec i e
in e en ion modali ies in add essing and p e en ing online g ooming.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
69
EMOTIONAL PROCESSING IN MALE PRISONERS: COMPARING PSYCHOPATHS
AND NON-PSYCHOPATHS
Daniela Ramos1, Ma ina Pinhei o1, Sónia Ca idade1, Olga Cunha2
1 Psychology Resea ch Cen e (CIPsi), School o Psychology, Uni e si y o Minho, Azu ém,
B aga
2 School o Psychology, Uni e si y o Minho; Lusó ona Uni e si y, Hei-Lab
[email p o ec ed]; [email p o ec ed].p ; [email p o ec ed];
[email p o ec ed]
Keywo ds: Emo ional P ocessing, Male P isone s, Psychopa hs
2030 Sus ainable De elopmen Goals: SDG16
Emo ional p ocessing in ol es pe cep ion, exp ession, and emo ional egula ion, which a e
cen al o in e pe sonal dynamics and daily decisions in a p ison en i onmen . Psychopa hy,
cha ac e ized by ai s such as lack o empa hy, manipula ion, and an isocial beha iou , is
o en associa ed wi h de ici s in emo ional p ocessing. Psychopa hic indi iduals end o exhibi
a low physiological esponse o s imuli ela ed o he su e ing o o he s, suppo ing he
ela ionship be ween hese wo a iables.
The main aim o his s udy is o in es iga e he di e ences in emo ional p ocessing be ween
psychopa hic and non-psychopa hic male inma es. Speci ically, he s udy aims o de e mine
whe he he e is a ela ionship be ween highe sco es on he a ec i e ace o psychopa hy
and g ea e de ici s in emo ional p ocessing.
This s udy employs a quan i a i e me hodology and a sample o 176 male inma es om p isons
in no he n Po ugal who a e conside ed impu able and o e 18 yea s old. The s udy will
consis o wo g oups: one composed o indi iduals wi h psychopa hy and he o he composed
o indi iduals wi hou psychopa hy. The s udy will use h ee measu es: a socio-demog aphic
and socio-legal ques ionnai e, he Sel -Repo Psychopa hy Scale-Sho Fo m, and he
Emo ional P ocessing Scale (EPS-25).
Psychopa hic inma es a e expec ed o exhibi de iciencies in emo ional p ocessing, pa icula ly
in a eas such as empa hy, emo ion ecogni ion, and emo ion egula ion. High sco es on
psychopa hic a ec i e ai s, such as lack o emo se o empa hy, a e p edic ed o be
co ela ed wi h hese de iciencies. These indings may e eal unique emo ional p ocessing
pa e ns in psychopa hic indi iduals, con ibu ing o a deepe comp ehension o psychopa hy.
This s udy explo es he ela ionship be ween psychopa hy and emo ional p ocessing. The
conclusions o his s udy could con ibu e o he de elopmen o mo e e ec i e s a egies in
he a ea o ehabili a ion and p e en ion o an isocial beha iou , as well as imp o ing men al
heal h p o essionals' unde s anding o he challenges aced by indi iduals wi h psychopa hic
ai s.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
70
EXECUTIVE FUNCTIONING AND EMPATHY IN MALE INMATES: A COMPARISON
BETWEEN VIOLENT AND NON-VIOLENT CRIMES
Ma ilde Soa es Gamelas1, Ma ina Pinhei o1, Sónia Ca idade1, Olga Cunha2
1 Psychology Resea ch Cen e (CIPsi), School o Psychology, Uni e si y o Minho, Gual a ,
B aga
2 School o Psychology, Uni e si y o Minho; Lusó ona Uni e si y, Hei-Lab
[email p o ec ed]; [email p o ec ed]; [email p o ec ed];
[email p o ec ed]
Keywo ds: Empa hy, Execu i e Func ioning, Inma es
2030 Sus ainable De elopmen Goals: SDG16
Empa hy can be seen as a p o ec i e ac o ha educes he likelihood o c iminal beha iou .
On he o he hand, de ici s in execu i e unc ioning a e ela ed o sel - egula ion p oblems, and
indi iduals wi h execu i e de ici s a e mo e likely o mani es agg ession. Empa hy in ol es
comp ehending and eac ing o he emo ional expe iences o o he s, while execu i e unc ion
plays a ole in egula ing ou emo ional esponses. This in e ac ion be ween execu i e
unc ioning and empa hy sugges s ha execu i e unc ion can ei he enhance o diminish
empa hic esponses. Resea ch indica es ha iolen o ende s exhibi lowe le els o empa hy
and highe execu i e de ici s compa ed o non- iolen o ende s, es ablishing a posi i e
co ela ion be ween hese a iables.
The eby, he main aim o he p esen s udy is o assess execu i e unc ioning and empa hy in
male inma es, analyse he ela ionship be ween hem, and explo e he po en ial di e ences
be ween indi iduals who commi ed iolen c imes and indi iduals who commi ed non- iolen
c imes.
A quan i a i e explo a o y c oss-sec ional s udy will be conduc ed, in which pa icipan s will be
ec ui ed om Po uguese male p isons. The sample will include 176 pa icipan s, who will be
di ided in o wo g oups, one composed o indi iduals who ha e commi ed iolen c imes and
he o he o indi iduals who ha e commi ed non- iolen c imes. In o de o collec he da a
needed, a socio-demog aphic and socio-legal ques ionnai e will be comple ed by he
pa icipan s, as well as he Basic Empa hy Scale (BES) and he F on al Assessmen Ba e y
(FAB).
Based on esea ch, in his in es iga ion i is expec ed ha indi iduals in p ison o iolen
c imes will show g ea e execu i e de ici s and less abili y o exp ess and eel empa hy
compa ed o non- iolen ones, and ha execu i e unc ioning and empa hy will be posi i ely
co ela ed.
This s udy can be conside ed highly signi ican as i could con ibu e o unde s anding he
ela ionship be ween execu i e unc ioning and empa hy in p isone s, inc easing esea ch on
his opic in Po ugal.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
77
ON-CHIP OPTICAL MICROSYSTEM FOR PLASMODIUM FALCIPARUM MALARIA
DETECTION
Vi ó ia Bap is a1, 2, 3, Gab iel Fe ei a1, G aça Minas1, 4, Ma ia Isabel Veiga2, 3,
Susana O. Ca a ino1, 4
1 Cen e o Mic oelec omechanical Sys ems (CMEMS-UMinho), School o Enginee ing,
Uni e si y o Minho, Campus de Azu ém, Guima ães, Po ugal
2 Li e and Heal h Sciences Resea ch Ins i u e (ICVS), School o Medicine, Uni e si y o
Minho, Campus de Gual a , B aga, Po ugal
3 Li e and Heal h Sciences ICVS/3B’s–PT Go e nmen Associa e Labo a o y, 4710-057
B aga/Guima ães, Po ugal
4 LABBELS – Associa e Labo a o y, B aga/Guima ães, Po ugal
[email protected] ; [email protected] ; [email protected] ;
ma ia e[email p o ec ed]minho.p ; sca a i[email p o ec ed]minho.p
Keywo ds: Spec opho ome y, Diagnosis, Mala ia
2030 Sus ainable De elopmen Goals: SDG1, SDG3, SDG4
The limi a ions in he cu en ly used diagnos ic me hods pose challenges o e ec i e mala ia
con ol and elimina ion. To o e come his, he ein, op ical spec opho ome y is explo ed o he
de ec ion and quan i ica ion o low-le el Plasmodium alcipa um in ec ions. Speci ically, we
cha ac e ize he op ical spec a o heal hy and in ec ed samples and design, simula e, and
ab ica e an on-chip op ical de ec ion mic osys em.
Fo a p elimina y cha ac e iza ion o samples, a 200 W Halogen sou ce di ec ed ligh on o he
sample and he subsequen ansmi ed o e lec ed ligh was de ec ed on a op-bench
spec opho ome e . The ab ica ed CMOS mic osys em ea u es a sophis ica ed a ay o 16
n+/p- subs a e silicon junc ion pho odiodes unc ioning as pho ode ec o s, coupled wi h 16
cu en - o- equency con e e s, and was es ed wi h heal hy and P. alcipa um-in ec ed ed
blood cells (RBCs).
The esul s indica e ha he abso bance and e lec ance spec a o he samples in he 400 –
800 nm ange can be mimicked by a se o 16 disc e e wa eleng hs. This acili a es he
de ec ion (when in eg a ed in o a diagnos ic de ice), allows he de ec ion o low le el
pa asi aemia (12 pa asi es/µL o RBCs) and po en ially disease quan i ica ion and s age
di e en ia ion. Addi ionally, he designed mic osys em was alida ed h ough ansmi ance
de ec ion o heal hy RBCs and in ec ed samples o 12, 25 and 50 pa asi es/µL.
O e all, ou s udy demons a ed ha he sensi i i y o spec opho ome y is compe i i e o he
one o he gold s anda d diagnos ic me hods, a i ming i s po en ial o mala ia diagnosis.
Fu he mo e, he inco po a ion o hese echnologies in o an a o dable and apid diagnos ic
de ice add esses he escala ing clinical demands o imp o ed mala ia con ol and elimina ion.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
78
FALL RISK ASSESSMENT IN OLDER ADULTS: TOWARDS REAL-TIME &
CONTINUOUS ESTIMATION
Luís Ma ins1, 2, 3, Nuno Ribei o1, C is ina San os1, 2, 3
1 CMEMS, Uni e si y o Minho, 4800-058 Guima ães, Po ugal
2 LABBELS—Associa e Labo a o y, 4710-057 B aga, Po ugal
3 LABBELS—Associa e Labo a o y, 4800-058 Guima ães, Po ugal
ma quesma [email protected]; nuno. e e e. ibei [email protected]; c is ina.san [email protected]
Keywo ds: Fall Risk Assessmen , Daily Ac i i ies, A i icial In elligence
2030 Sus ainable De elopmen Goals: SDG3
Falls a e a p e alen cause o inju ies in he elde ly, escala ing ea men cos s and
emphasizing he impo ance o eal- ime Fall Risk Assessmen (FRA) ools. While wea able
de ices, such as wais bands o sma wa ches linked o sma phones, ha e been explo ed o
FRA in eg a ion, u he e inemen is impe a i e. This s udy add esses he c i ical need o
s a egies ha p omp ly iden i y isky si ua ions, conside ing a b oad spec um o ac o s, o
assis senio s and mi iga e all consequences. The p ima y objec i e is he de elopmen and
alida ion o a con inuous, objec i e, and mul i ac o ial FRA ool.
The en isioned FRA s a egy emphasizes ine ial da a-based ecogni ion o Ac i i ies o Daily
Li ing (ADLs) in he elde ly and employs a ipa i e modula a chi ec u e o eal- ime all isk
assessmen , inco po a ing a wais band wi h an ine ial senso and an eHeal h applica ion.
Each module, using A i icial In elligence (AI) me hods, sc u inizes a widesp ead ange o isk
ac o s, including mo emen da a, biological da a, en i onmen al changes, and beha iou al
aspec s o gi e an objec i e and pe sonalized FRA.
The alida ion o he en isioned ool commenced wi h he ADLs ecogni ion module, employing
an ine ial da a collec ion p o ocol. Da a om 8 un es ic ed ADLs, including as ansi ional
ADLs, pe o med by 54 senio indi iduals in con inuous and un es ic ed condi ions, we e
ga he ed in 6 di e en nu sing homes. A igo ous 2-s ep alida ion and op imiza ion o a ious
Deep Lea ning (DL) models (CNN, LSTM, and CNN-LSTM) was pe o med, e ealing highly
sa is ac o y subjec -independen ecogni ion esul s and a end owa ds op imizing window
size o enhanced algo i hm pe o mance.
The CNN-LSTM a chi ec u e demons a ed he mos p omising esul s, achie ing he highes
accu acy ac oss all ADLs in a Lea e-p-ou c oss- alida ion o 9 es subjec s. While no
uni o m ac oss all ADLs, he po en ial o neu al ne wo ks highligh s AI algo i hms as u u e
solu ions o ecognizing un es ic ed ADLs, p omising con inuous and eal- ime FRA in olde
adul s. Fu u e wo k should ocus on e ining DL models, acqui ing addi ional da a om elde ly
indi iduals and alida ing he emaining modules o he de ined FRA s a egy.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
79
INSTITUTO DE CIÊNCIAS DA TERRA
INSTITUTE OF EARTH SCIENCES
ICT
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
80
DEVELOPING A 3D WEB-GIS MAPPING PLATFORM TO SUPPORT SEISMIC
VULNERABILITY ASSESSMENT OF URBAN AREAS: AN INTRODUCTION
Ósca Cos a1, Paula Ma inho Reis1, Raquel Menezes2, An ónio Sil a3
1 Ins i u o de Ciências da Te a (ICT) – Polo Minho, Uni e sidade do Minho, Campus de
Gual a , 4710 – 057 B aga
2 Cen o de Ma emá ica, Uni e sidade do Minho
3 LRB – In es imen os e Consul o ia, Lda.
osca ilipeand [email protected]; [email p o ec ed], [email p o ec ed],
[email p o ec ed]
Keywo ds: Ea hquake, U ban Resilience, Decision suppo ool
2030 Sus ainable De elopmen Goals: SDG1, SDG9, SDG11
In 2020, na u al disas e s globally a ec ed a ound 100 million people, causing subs an ial
economic and human losses. The popula ion densi y in low-lying coas al o i e side a eas
heigh ens he isk o signi ican impac s om na u al disas e s. Due o i s loca ion, Po ugal's
ec onic en i onmen induces low o mode a e seismic and co-seismic haza ds wi h he
po en ial o conside able economic and human losses, especially in u ban a eas like Lisbon,
unde lying he u gency o enhanced isk assessmen and p epa edness s a egies. While
obus seismic isk models exis o Lisbon, he absence o a use - iendly ool capable o
au oma ically es ima ing eal- ime ea hquake damages and sa e escue pa hways is a no able
gap. This is whe e he p oposed 3D web-GIS pla o m will play an impo an ole.
This pla o m aims o p o ide dynamic maps ha illus a e he ci y's ulne abili y o hese
na u al disas e s. The inco po a ion o 3D model buildings will enhance he isualiza ion and
communica ion o po en ial impac s and losses, hus acili a ing mo e e ec i e p e en i e and
esponse measu es. The pla o m's dynamic na u e allows he in eg a ion o a ious models,
including hose o assessing building collapse isks and iden i ying p io i y a eas and sa e
escue ou es. Wi h dynamic, isual, and in e ac i e ep esen a ion o seismic isk da a, he
pla o m will enhance seismic ulne abili y comp ehension and imp o e he decision-making
p ocess o a ious s akeholde s. Fo policymake s and u ban planne s, his pla o m will o e
a powe ul ool o isualizing he po en ial impac s o seismic e en s, aiding mo e e ec i e
u ban planning and isk mi iga ion s a egies. I will also p o ide eme gency esponse eams
wi h c i ical in o ma ion o swi and sa e esponse ac ions in he a e ma h o an ea hquake,
po en ially sa ing li es and educing economic losses, ul ima ely con ibu ing o sa e , mo e
esilien u ban en i onmen s.
The PhD hesis, en i led "De eloping a 3D Web-GIS Mapping Pla o m o Suppo he Seismic
Vulne abili y Assessmen o U ban A eas," which o ms he basis o his abs ac , is in i s ea ly
s age. The esea ch is cu en ly in a comp ehensi e li e a u e e iew, concen a ing on seismic
isk modelling, speci ically in Lisbon Ci y. This ini ial s age is c ucial o iden i ying po en ial
gaps and oppo uni ies in cu en me hodologies, which will in o m and guide he de elopmen
o he web-GIS pla o m.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
81
INSTITUTO DE INVESTIGAÇÃO EM CIÊNCIAS DA VIDA E DA SAÚDE
LIFE AND HEALTH SCIENCES RESEARCH INSTITUTE
ICVS
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
82
SPATIOTEMPORAL PROFILING OF GENE EXPRESSION DURING SARCOID
GRANULOMA FORMATION
Ma cela Oli ei a1, 2, Relbe Aguia Gonçales1, 2, Ana Bap is a1, 2, Daniela
An unes1, 2, Nuno Osó io1, 2, Hélde No ais e Bas os3, 4, 5, 6, C is ina Cunha1, 2,
Agos inho Ca alho1, 2
1 Li e and Heal h Sciences Resea ch Ins i u e (ICVS), School o Medicine, Uni e si y o
Minho, Campus Gual a , 4710-057 B aga, Po ugal
2 ICVS/3B’s – PT Go e nmen Associa e Labo a o y, B aga/Guima ães, Po ugal
3 i3S - Ins i u o de In es igação e Ino ação em Saúde, Po o, Po ugal
4 IBMC – Ins i u o de Biologia Molecula e Celula , Po o, Po ugal
5 Depa men o Pneumology, Hospi al de São João, Po o, Po ugal
6 Depa men o Pneumology, Hospi al de B aga, B aga, Po ugal
[email protected] ; [email protected] ; [email protected] ;
[email protected] ; noso [email protected] ; hno aisbas [email protected] ;
[email p o ec ed]; [email p o ec ed]
Keywo ds: Sa coidosis, RNA-sequencing, IL-17 signalling
2030 Sus ainable De elopmen Goals: SDG3, SDG9, SDG10
G anuloma ous lung diseases encompass an a ay o diso de s caused by bo h in ec ious and non-
in ec ious agen s in combina ion wi h gene ic suscep ibili y and en i onmen al ac o s. Sa coidosis is a
mul isys emic disease wi h unknown e iology cha ac e ized by he p esence o epi helioid, non-
nec o izing g anulomas in se e al o gans, p edominan ly he lungs. The g anuloma ous esponse
in ol es a s epwise p og am in which a se ies o mac ophage ans o ma ions ec ui s addi ional cells
o p oduce s uc u al and molecula modi ica ions. None heless, he egula ion o he local ansc ip ional
landscape du ing g anuloma o ma ion.
To ul il his gap, we ha e eso ed o a mouse model o g anuloma o ma ion o dissec he
ansc ip ional dynamics o isola ed g anulomas du ing hei o ma ion, namely he ea ly (day 0),
in e media e (day 2) and la e (day 4) s ages.
RNA-sequencing analysis o mic odissec ed g anulomas e ealed ha he majo i y o he di e en ially
exp essed genes (DEGs) is no iceable wo days a e elici ing g anuloma o ma ion (568 DEGs) wi h
genes like and Re nla, Mmp12, Saa3 and Acod1 being up egula ed and di ec ly/indi ec ly in ol ed in
he in lamma o y esponse and genes like Tmem100 and Dpep1 implica ed wi h pep ide me abolism
down egula ed. A his ime poin , he mos p onounced pa hways included he ones ela ed wi h
chemokines, chemokine ecep o s, and he complemen sys em. P ocesses ela ed wi h s uc u al
al e a ions a e mo e p onounced in la e s ages, such as ex acellula ma ix o ganiza ion and pa hways
ela ed o ib onec in ma ix o ma ion. Ou esul s also poin ou classical pa hways in ol ed in he
in lamma o y esponse such as TNF, NF-Kβ and complemen cascade. Besides, IL-17 signalling also
appea s o be c i ically implied h oughou he g anuloma o ma ion p ocess (gene a io o 0.23).
Pa icula ly, DEGs ela ed wi h IL-17-media ed signals a e dis inc i ely exp essed ac oss all s ages o
g anuloma o ma ion, and mo e p ominen ly a he in e media e s age.
O e all, he spa io empo al mapping o he ansc ip omic signa u es upon g anuloma o ma ion pinpoin
he mos impo an pa hways, and indi idual genes as po en ial a ge s o u he explo e using
pha macological inhibi ion o in i o models.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
83
GENETIC VARIATION IN IL-37 INFLUENCES THE IMMUNE RESPONSE TO
ASPERGILLUS FUMIGATUS AND PREDISPOSES TO FUNGAL DISEASE AFTER
STEM-CELL TRANSPLANTATION
Inês Caldei a1, 2, Ri a Sil a-Gomes1, 2, Samuel M. Gonçal es1, 2, Raquel
Fe nandes1, 2, Cha les A. Dina ello3, F ank L. an de Vee donk4, C is ina
Cunha1, 2, Agos inho Ca alho1, 2
1 Li e and Heal h Sciences Resea ch Ins i u e (ICVS), School o Medicine, Uni e si y o
Minho, B aga, Po ugal
2 ICVS/3B’s - PT Go e nmen Associa e Labo a o y, Guima ães/B aga, Po ugal
3 Depa men o Medicine, Uni e si y o Colo ado, Au o a, 80045, USA
4 Depa men o In e nal Medicine, Radboud Uni e si y Medical Cen e , Nijmegen, he
Ne he lands
[email protected] ; [email protected] ; [email protected] ;
[email protected] ; cdina [email protected]; F ank. andeVee donk@ adboudumc.nl;
[email p o ec ed]; [email p o ec ed]
Keywo ds: Aspe gillosis, An i ungal Immuni y, In e leukin-37
2030 Sus ainable De elopmen Goals: SDG3, SDG9, SDG10
In asi e pulmona y aspe gillosis (IPA) is a li e- h ea ening in ec ion, pa icula ly among pa ien s
unde going chemo he apy o allogeneic hema opoie ic s em cell ansplan a ion (HSCT), caused by he
ungal pa hogen Aspe gillus umiga us. Among se e al clinical isk ac o s, gene ic a ia ions may
ende indi iduals mo e suscep ible o IPA. The e o e, he iden i ica ion o allelic pa e ns ha p edispose
o a highe isk o disease is essen ial o isk s a i ica ion and consequen ly he de elopmen o p e-
emp i e diagnos ics o pa ien s a high isk o IPA.
The balance be ween p o- and an i-in lamma o y esponses is a p e equisi e o success ul an i ungal
hos de ences. Al hough in lamma ion is an essen ial componen o he p o ec i e esponse o ungi, i s
dys egula ion may signi ican ly wo sen ungal diseases and limi an i ungal immune esponses. A newly
desc ibed nega i e egula o o in lamma o y esponses is in e leukin-37 (IL-37), an immunosupp essi e
cy okine om he IL-1 amily ha exe s b oad p o ec i e e ec s in au oimmune and in lamma o y
diseases. In he con ex o in ec ion, IL-37 was demons a ed o be able o inhibi in lammasome
ac i a ion and disease se e i y in mu ine aspe gillosis. IL-37 is p oduced by se e al non-immune and
immune cells, including mac ophages, and has been desc ibed as a undamen al supp esso o inna e
and acqui ed immuni y.
In his s udy, we aimed o dissec he con ibu ion o gene ic a ia ion wi hin he IL37 gene o he isk o
IPA in high- isk pa ien s.
Ou esul s demons a e ha he dono s3811047 a ian in IL37 was signi ican ly associa ed wi h an
enhanced isk o IPA a e ansplan a ion, as demons a ed by he highe cumula i e incidence o IPA
displayed by pa ien s who ecei ed a ansplan om dono wi h he AA o he GA geno ypes han
pa ien s wi h GG dono s (34% and 16%, espec i ely, P=0.0006). Suppo ing hese da a, we ound ha
he s3811047 a ian in IL37 egula ed al eola cy okine p oduc ion in pa ien s, wi h AA o GA geno ype
ca ie s displaying lowe le els o TNF and IL-1b in he b onchoal eola la age luids (BALs) when
compa ed o pa ien s wi h he GG geno ype. Mo eo e , human monocy e-de i ed mac ophages om
heal hy dono s om AA o GA dono s displayed an impai ed abili y o elimina e he ungus in an in i o
in ec ion model, compa ed o GG mac ophages.
O e all, ou esul s unco e , o he i s ime, he pu a i e clinical ele ance o gene ic a ia ion in IL-37
in he egula ion o suscep ibili y o IPA.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
84
ENHANCING MALARIA ELIMINATION STRATEGIES IN THE DOMINICAN REPUBLIC:
EVALUATING RAPID DIAGNOSTIC TEST ACCURACY AND UNRAVELING
PARASITE GENETIC DIVERSITY
Claudia Fede o1, 2, 3, F ancisco Cue as3, Isaac Miguel3, Ana Ma ga ida
Gonçal es1, 2, Vi o ia Bap is a, Ma iagiulia Con e, Nuno Oso io1, 2, Modes o
C uz3, Ma ia Isabel Veiga1, 2, 3
1 Li e and Heal h Sciences Resea ch Ins i u e (ICVS), School o Medicine, Uni e si y o
Minho, B aga, Po ugal
2 ICVS/3B’s - PT Go e nmen Associa e Labo a o y, B aga/Guima ães, Po ugal
3 Au onomous Uni e si y o San o Domingo
[email p o ec ed]; ankxa ie _04@ho mail.com; [email protected];
[email p o ec ed]; [email p o ec ed]; modes o_c [email protected]; ma ia eig[email p o ec ed]ho.p
Keywo ds: Mala ia, Rapid diagnos ic es , Molecula su eillance
2030 Sus ainable De elopmen Goals: SDG3, SDG10, SDG11
Mala ia emains a signi ican public heal h conce n in opical egions globally, cha ac e ized
by challenges such as limi ed diagnos ic ools, d ug esis ance, and he compounding impac
o he COVID-19 pandemic. Dominican Republic (DR), a pa icipan coun y in he E2025 WHO
p og am o mala ia elimina ion, con on s dis inc i e challenges due o ongoing ansmission
o Plasmodium alcipa um. This s udy me iculously assesses he accu acy and limi a ions o
mala ia Rapid Diagnos ic Tes s (RDTs) in DR, del es in o he gene ic di e si y o Plasmodium
spp, and explo es ac o s con ibu ing o he high p e alence o P. alcipa um on he island.
A comp ehensi e molecula analysis in ol ing 1,653 samples om suspec ed mala ia cases
in Dominican Republic, ou s udy unco e ed a 2.3% alse nega i e a e o Rapid Diagnos ic
Tes s (RDTs). Employing quan i a i e polyme ase chain eac ion (qPCR), we iden i ied ha all
alse nega i e RDTs con ained Plasmodium spp. a low-le el pa asi emia, unde sco ing he
impe a i e o mo e sensi i e diagnos ic ools, such as molecula analyses. Del ing deepe
in o he Plasmodium spp. landscape, ou indings e ealed ha P. alcipa um accoun ed o
he en i e y o cases, excep o a singula incidence o P. i ax. Addi ionally, geno yping he
Du y domain s2814778 mu a ion showcased a signi ican gene ic di e si y, wi h 59% o
samples exhibi ing Du y-nega i e s a us, po en ially in luencing mala ia suscep ibili y and
ansmission dynamics.
This s udy unde sco es he limi a ions o RDTs in de ec ing low-densi y pa asi e in ec ions,
posing challenges o mala ia elimina ion e o s in DR. The de ec ion o P. i ax aises
conce ns abou elapse, emphasizing he necessi y o inno a i e su eillance and disease
managemen s a egies. These indings con ibu e aluable insigh s o shape u u e mala ia
con ol app oaches, s ee ing e o s owa d achie ing he 2025 elimina ion goal and
unde sco ing he signi icance o con inued esea ch endea o s in his c i ical domain.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
85
NORADRENERGIC DEGENERATION IN A DJ-1 KNOCKOUT MOUSE MODEL
Filipa Fe ei a-An unes1, 2, Belém Sampaio-Ma ques1, 2, Jonas Campos1, 2,
Daniela Mon ei o-Fe nandes1, 2, Sand a Ba a a-An unes1, 2, And eia G. Pinho1, 2,
Bá ba a Mendes-Pinhei o3, Ana Ma o e4, An ónio J. Salgado1, 2
1 Li e and Heal h Sciences Resea ch Ins i u e (ICVS), School o Medicine, Uni e si y o
Minho, B aga, Po ugal
2 ICVS/3B's Associa e Lab, PT Go e nmen Associa ed Lab, B aga/Guima ães, Po ugal
3 S emma e s, Bio ecnologia e Medicina Regene a i a S.A, Guima ães, Po ugal
4 i3S - Ins i u o de In es igação e Ino ação em Saúde, Uni e sidade do Po o, Po o,
Po ugal
p[email p o ec ed]; [email p o ec ed]
Keywo ds: Pa kinson’s Disease, DJ-1, No ad enaline
2030 Sus ainable De elopmen Goals: SDG3
Pa kinson’s disease (PD) is he second mos common neu odegene a i e diso de , wi h
app oxima ely 10% amilial cases, caused by se e al iden i ied mu a ions, such as in he DJ-1
gene. DJ1 knockou (KO) mouse models ha e been shown o p esen p og essi e mo o
beha io al de ici s, wi hou signi ican al e a ions in he nig os ia al dopamine gic sys em,
desc ibed as he neu opa hological subs a e o PD. Degene a ion o he no ad ene gic
nucleus - locus coe uleus (LC) - has been linked o he de elopmen o non-mo o symp oms
and o he agg a a ion o mo o symp oms.
We aimed o s udy he in ol emen o LC degene a ion in a DJ-1 KO model looking a bo h
mo o and non-mo o pheno ype. Fo ha , we ha e adminis e ed a selec i e no ad ene gic
neu o oxin (DSP-4) in DJ-1 KO mice. Fi s , we op imized he app op ia e dosage o be
adminis e ed. To assess unc ional al e a ions, we ha e pe o med a ba e y o beha io al es s
co e ing se e al symp oms associa ed wi h PD, including dep ession, anxie y, cogni i e
impai men s, impai ed locomo o ac i i y and gai dys unc ion. To assess he his ological
e ec s o bo h DSP-4 and he mu a ion we ha e pe o med Ty osine Hyd oxylase (TH)
immunohis ochemis y on he LC, subs an ia nig a (SNpc), and s ia um (STR).
DJ-1 animals ha e shown endencies o impai ed mo o unc ioning, gai dys unc ion and a
endency o de elop anxie y- ela ed o no el y. DJ-1 KO ea ed wi h DSP-4 showed impai ed
swimming abili y, gai dys unc ion, endency o dep essi e-like beha io , and imp o ed ea
memo y e ie al. DJ-1 animals showed a educ ion o 42.6% in s ia al densi ome y and a
dec ease in he numbe o TH+ cells in he SNpc compa ed o WT li e ma es. The injec ion o
DSP-4 led o a dec ease o 83-85% neu ons wi hin he LC. DSP-4 adminis a ion in DJ-1 mice
led o a 58% dec ease in dopamine gic ibe s con en in he s ia um bu did no a ec nig al
neu ons.
In his wo k, we de eloped a model capable o ecapi ula ing no ad ene gic degene a ion
desc ibed in PD, which led o signi ican nig os ia al degene a ion, and was ansla ed in o
mild beha io al pheno ype, a he mo o and non-mo o le el. This model may p o ide a
sui able app oach o he s udy o neu op o ec i e he apies ocused on he LC no ad ene gic
neu ons.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
86
ITACONATE DEFICIENCY ENHANCES ANTI-FUNGAL EFFECTOR FUNCTIONS OF
MACROPHAGES AND CONFERS RESISTANCE TO INFECTION WITH ASPERGILLUS
FUMIGATUS
Raquel Fe nandes1, 2, Samuel Gonçal es1, 2, Ri a Sil a-Gomes1, 2, Inês Caldei a1,
2, Inês Pinhei o1, 2, Miguel Fe nández-Ga cía3, Co al Ba bas3, Fe nando
Rod igues1, 2, C is ina Cunha1, 2, Agos inho Ca alho1, 2
1 Li e and Heal h Sciences Resea ch Ins i u e (ICVS), School o Medicine, Uni e si y o
Minho, 4710-057 B aga, Po ugal
2 ICVS/3B’s - PT Go e nmen Associa e Labo a o y, Guima ães/B aga, Po ugal
3 Cen o de Me abolómica y Bioanálisis (CEMBIO), Facul ad de Fa macia, Uni e sidad San
Pablo CEU, CEU Uni e si ies, Mad id,
[email protected] ; [email protected] ; [email protected] ;
[email protected] ; [email protected] ; miguel. e nandezga [email protected];
[email p o ec ed]; [email p o ec ed]; c is i[email p o ec ed];
[email p o ec ed]
Keywo ds: Aspe gillosis, I acona e, Immunome abolism.
2030 Sus ainable De elopmen Goals: SDG3, SDG9, SDG10
The success o cance chemo he apy and solid o gan and s em-cell ansplan a ion has,
pa adoxically, inc eased he popula ion o immunocomp omised pa ien s. These pa ien s display
ex eme suscep ibili y o oppo unis ic li e- h ea ening o ms o ungal in ec ions, such as in asi e
pulmona y aspe gillosis (IPA), a de as a ing in ec ion caused p ima ily by he ungal pa hogen
Aspe gillus umiga us. O e 30 million people wo ldwide a e a isk o IPA, wi h >300,000 cases o
in ec ion epo ed each yea . I s challenging diagnosis coupled o he absence o licensed accines
and ine ec i eness o an i ungal d ugs ha e esul ed in signi ican mo ali y and economic bu den.
Dissec ing he complex pa hogenesis o IPA equi es a molecula unde s anding o he
physiological p ocesses o an i ungal immuni y. I is known ha , in esponse o in ec ion, ac i a ed
myeloid cells display enhanced exp ession o he immune- esponsi e gene 1 (IRG1), which
encodes he aconi a e deca boxylase 1 (ACOD1) ha ca alyzes he deca boxyla ion o he
ica boxylic acid cycle in e media e cis-aconi a e o i acona e. I acona e has been widely
ecognized by i s immuno egula o y and an imic obial p ope ies and e en hough he p ecise
mechanisms con olled by his me aboli e a e no ully cla i ied, i s ne - unc ion is hough o be an i-
in lamma o y. Hence, we aimed o elucida e he con ibu ion o ACOD1 unc ion and i acona e o
hos de ense agains he oppo unis ic ungal pa hogen A. umiga us. We ound ha in ec ion o
bone ma ow-de i ed mac ophages (BMDMs) wi h A. umiga us esul ed in inc eased exp ession
o Acod1 and consequen i acona e p oduc ion. In e es ingly, BMDMs om Acod1-/- mice displayed
an enhanced abili y o phagocy ose and elimina e conidia o A. umiga us compa ing o wild- ype
mac ophages, a pheno ype ha was comp omised when Acod1-/- mac ophages we e p e- ea ed
wi h i acona e, highligh ing a possible unexpec ed and de imen al ole o i acona e du ing A.
umiga us in ec ion. Since no di e ences we e obse ed ega ding he p oduc ion o eac i e
oxygen species be ween mac ophages o he wo backg ounds, we a e cu en ly explo ing a
possible di ec ole o i acona e as a “ i ulence igge ” ha leads o enhanced ungal ge mina ion
and/o emodels he ungal cell wall. O no e, A. umiga us exposed o di e en concen a ions o
i acona e displayed di e en pa e ns o ge mina ion in a dose dependen -manne .
Al oge he , hese esul s highligh a possible de imen al ole o i acona e in an i ungal immuni y
and shed ligh on a possible new mechanism in ol ed in he pa hogenesis o IPA.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
93
MAGNETICALLY TRIGGERED SHAPE DEFORMATION OF POLYURETHANE
COMPOSITES
Ma iana M. Sil a1, José A. Co as1, Ma ia C. Pai a1, Ma iana P. P oença2
1 Ins i u e o Polyme s and Composi es, Depa men o Polyme Enginee ing, Uni e si y o
Minho, 4800-058 Guima ães, Po ugal
2 ISOM and Depa amen o de Elec ónica Física, Uni e sidad Poli écnica de Mad id, A da.
Complu ense 30, 28040 Mad id, Spain
mmsil [email protected] ; jco [email p o ec ed]nho.p ; mcpai [email protected] ;
ma iana.p oenc[email p o ec ed]
Keywo ds: Shape-memo y polyme s, Magne ic pa icles, The moplas ic polyu e hane
2030 Sus ainable De elopmen Goals: SDG9
G an ing magne ic p ope ies o ubbe y polyme s opens possibili ies o gene a e sma
ma e ials o mul iple applica ions, allowing e e sible de o ma ions unde a magne ic ex e nal
s imulus. Magne ic esponsi e shape-memo y polyme composi es can be designed a low
magne ic pa icle con en o enable emo e ac ua ion, achie ing shape de o ma ion by
induc i e hea ing o magne o heological e ec s.
Comme cial (Sigma-Ald ich) and sol-gel syn hesized Y ium-I on Ga ne (YIG, Y3Fe5O12)
nanopowde (NP) as desc ibed in he li e a u e we e cha ac e ised be o e and a e calcina ion
a 1000 °C. The moplas ic polyu e hane (TPU) composi es wi h loads om 5 o 40 w .% o
calcined comme cial YIG we e p oduced by comp ession moulding. Thei shape-memo y
abili y was es ed unde a magne ic ield.
The mal ea men o YIG NP (3h a 1000ºC) modi ied he s uc u e o comme cial and sol-gel
syn hesized (pH 10) YIG NP, inc easing he sa u a ion magne iza ion o he pa icles. All
TPU/YIG composi es display a magne ic esponse ha inc eases wi h YIG con en . Shape-
memo y beha io , igge ed by a magne ic ield o 500 G, was obse ed o all he composi es
wi h calcined and sol-gel syn hesized YIG.
A simple me hod was used o p oduce composi es wi h YIG pa icles, ha display magne ic
esponse a low pa icle loading. Such composi es espond o a magne ic ield, displaying a
shape-memo y beha io , and can be used as so ac ua o s, o example, in so obo ics.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
94
STUDY OF ORGANOLEPTIC ADDITIVES AND INSECT REPELLENTS FOR POST-
CONSUMER RECYCLED POLYOLEFINS
Camila Pe ei a, Ca la I. Ma ins
Ins i u e o Polyme s and Composi es (IPC), Uni e si y o Minho, Azu ém, Guima ães
[email p o ec ed]; [email p o ec ed]
Keywo ds: Pos -consume ecycled ma e ials, Ro a ional molding, O ganolep ic
2030 Sus ainable De elopmen Goals: SDG12
Pos -consume ecycled (PCR) ma e ials a e becoming a ailable o he subs i u ion o i gin
plas ic ma e ials. They a e a iable al e na i e solu ion o inc easing hei ci cula i y. The
ecycling p ocess may educe he o e all p ope ies o he plas ics and he inal p oduc may
exhibi undesi able odo s. The e o e, his esea ch e alua es he p ocessing and p ope ies o
pos -consume ecycled polye hylene wi h a oma ic addi i es o deli e ac i e insec epellency
and ag ance in p oduc s made by o a ional molding. This echnique is known o he
manu ac u ing o hollow pa s h ough a slow p ocess a high empe a u es in an oxida i e
a mosphe e. The e o e, i ’s impo an o e alua e he p ope ies o bo h he polyme ic ma ix
and addi i es, as hey mus emain s able unde such condi ions.
This s udy aims o p oduce pa s made om ecycled polyme ma ix imp egna ed wi h
ag ance addi i es, in solid and liquid s a es. The polyme ic ma ix used was Si blend R 00
040 CS AX, p o ided by SIRPLASTE (Po o de Mós, Po ugal), a ecycled high-densi y
polye hylene (HDPE) in powde o m, whe eas he addi i es we e ci onella oil, cinnamon
powde , and lau el powde . The in es iga ion ocused on he e ec o he addi i es on PCR-
HDPE, i s p ocessing cha ac e is ics, and also on he mo phological and mechanical
p ope ies o he pa s. A mix u e con aining 3% by mass o he addi i e was used o his
pu pose.
P is ine and compounded ma e ials we e cha ac e ized by g anulome y, d y low, appa en
densi y, mel low index (MFI), di e en ial scanning calo ime y (DSC), he mog a ime ic
analysis (TGA) and Fou ie T ans o m In a ed Spec oscopy (FTIR). The inco po a ion o
addi i es did no cause signi ican changes in mel ing and c ys alliza ion empe a u es,
implying ha hei p esence does no in luence he s uc u al o ganiza ion o he polyme
ma ix. The MFI esul s indica ed a plas icizing e ec o he oil. Fu he mo e, i s addi ion
educed he appa en densi y and hinde ed he d y low; ha was a ibu ed o he polyme ’s
humidi ica ion. Despi e o ha , he di ec in oduc ion o oil imp o ed he su ace inish o he
pa , educing he occu ence o su ace pinholes. In he case o powde ed addi i es, pinholes
we e abundan , as well as oids on he pa . The ci onella, cinnamon and lau el ag ances
we e well p esen in he pa s a e p ocessing.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
95
DEVELOPMENT OF ECO-SUSTAINABLE COMPOSITE SANDWICH STRUCTURAL
PANELS
Rui Pe ei a1, B aian U ibe2, Paulo An unes2
1 Depa men o Polyme Enginee ing, Uni e si y o Minho, 4800-058 Guima ães, Po ugal
2 PIEP, 4800-058 Guima ães, Po ugal
ui2001.pe ei a@ou look.p
Keywo ds: Eco-sus ainable, Sandwich s uc u e, Composi es
2030 Sus ainable De elopmen Goals: SDG9, SDG12
The pape discusses he de elopmen o an eco-sus ainable composi e sandwich s uc u e
ha p esen s good physical and mechanical p ope ies. This ype o s uc u es has applica ions
in a ious a eas, om cons uc ion o ailways, whe e ma e ials wi h a high s eng h- o-weigh
a io a e equi ed. Cu en ly, he ma e ials mos used in he cons uc ion o hese s uc u es
a e based on he mose ing esins, polyu e hane oams, and polys y ene, among o he s.
Al hough hese ma e ials pe o m well mechanically, hey a e no eco-sus ainable and canno
be eused a e hei li espan. To o e come his limi a ion, we in es iga e he easibili y o
eplacing con en ional ma e ials used in he cons uc ion o sandwich s uc u es wi h eco-
sus ainable ma e ials. To achie e his goal, he p ojec has speci ic s ages: 1) p oduce a
p o o ype sandwich panel h ough ho comp ession echniques; 2) de elop a honeycomb co e
wi h p op ie a y echnology ha allows he manu ac u e o a highly igid composi e s uc u e;
3) cha ac e ize he mechanical and physical p ope ies o he sandwich composi e s uc u e o
ensu e i s echnical iabili y.
The ob ained p o o ype was made o he moplas ic esin and bio-based ein o ced ibe s.
Addi ional e alua ion es s a e sugges ed o con i m he mechanical and he mal p ope ies,
including low- eloci y impac esis ance, comp essi e s eng h, he mal insula ion,
lammabili y, and o he ele an p ope ies. Thus, i is expec ed o p o ide he indus y wi h he
oppo uni y o subs i u e con en ional sandwich panel s uc u es wi h en i onmen ally iendlie
al e na i es.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
96
CALCULATING THE CARBON FOOTPRINT OF PLASTIC PARTS
Ma iana Lima1, Ca la I. Ma ins1, Rica do Simões1, Tiago Ba bosa2
1 Ins i u e o Polyme s and Composi es (IPC), Uni e si y o Minho, Azu ém, Guima ães
2 Fehs Componen es Lda, Fe ei os, B aga
[email p o ec ed] [email p o ec ed]; [email p o ec ed]
Keywo ds: G eenhouse Gas Emissions, Ca bon Foo p in , En i onmen Managemen ,
Plas ics
2030 Sus ainable De elopmen Goals: SDG9, SDG12, SDG13
This abs ac p o ides insigh s on he impo ance o calcula ing he Ca bon Foo p in o plas ic
pa s and how his calcula ion can be o bene i o he au omo i e indus y. The aim o his wo k
is o calcula e he Ca bon Foo p in o a deco a i e plas ic pa o he au omo i e indus y. The
pa consis s on an injec ion moulded pa made o PC/ABS and a TPS s oppe , which is hen
pain ed wi h a high-gloss pain . A s eel sp ing is a ached o he pa a e paining. The wo k
enables a de ailed assessmen o he pa 's li e cycle, p o iding a comp ehensi e o e iew o
he en i onmen al implica ions o his p oduc , as well as iden i ying oppo uni ies o educing
emissions h oughou he p oduc ion chain.
The e iew begins by elucida ing he undamen al p inciples o he p oduc ion p ocesses o he
p oduc unde s udy, he Ca bon Foo p in , he me hodologies o be conside ed o calcula ing
he Ca bon Foo p in and he a ious possible app oaches o speci y he li e cycle o a p oduc .
All he ac i i ies necessa y o he p oduc ion o he pa s we e i s es ablished. They consis ed
b ie ly on he injec ion mould o he pa s, pain ing o he PC/ABS pa , moul ing he TPS
s oppe and inally assemble he s eel sp ing. The necessa y da a such as ene gy powe
consump ion, emission ac o s and alloca ion ac o s we e u he collec ed.
The Ca bon Foo p in alue was ob ained by adding up he Ca bon Foo p in o all he li e cycle
s ages, which is ob ained by mul iplying he emission ac o by he consump ion. I he s age
is ela ed o anspo , i is also mul iplied by he alloca ion ac o .
I was concluded ha pain ing o he pa and anspo a ion o he p oduc o he clien (buye )
whe e he mos ele an s eps o g eenhouse gases emission. The pain ing p ocess has a
highe pe cen age o sc ap and la ge quan i ies o GHG a e emi ed esul ing om ha . The
anspo o he p oduc o he buye is also impo an , since he GHG emissions do no depend
exclusi ely on he company. This highligh ed he need o in ol e he supply chain in an e o
o educe he ca bon oo p in and o apply his me ic o o he p oduc s.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
97
PROCESSING AND CHARACTERIZATION OF POST-CONSUMER RECYCLED
MATERIALS FOR ROTATIONAL MOULDING APPLICATIONS
Ma ia S. Ribei o, Ca la I. Ma ins
Ins i u e o Polyme s and Composi es (IPC), Uni e si y o Minho, Azu ém, Guima ães
[email p o ec ed], [email p o ec ed]
Keywo ds: Pos -consume ecycled (PCR) polyme s, Ro a ional moulding, polyme
p ope ies
2030 Sus ainable De elopmen Goals: SDG12
The ci cula economy has become an inc easingly una oidable issue o he plas ics
p ocessing indus y. The mechanical ecycling o he moplas ic polyme s is a good oppo uni y
o add ess his ma e and o educe he consump ion o i gin aw ma e ials and o ob ain
p oduc s a e y low cos s. This wo k belongs o an ongoing s udy in o he use o pos -
consume ecycled (PCR) polyme s, p edominan ly consis ing o ecycled high-densi y
polye hylene (HDPE) , p o ided by SIRPLASTE company (Po ugal) in powde o m o
o a ional molding applica ions. This p ocessing echnique is ypically used o p oduce la ge
hollow, igid and esilien s uc u es, like anks, kayaks, leisu e u ni u e, e c. The s udy
includes a comp ehensi e analysis o he ma e ial in e ms o i s composi ion, he mal and
physical cha ac e is ics by means o Fou ie T ans o m In a ed Spec oscopy (FTIR),
Di e en ial Scanning Calo ime y (DSC), Mel low Index (MFI), appa en densi y, d y low and
g anulome y and also p ocessing and cha ac e iza ion o pa s. The esul s iden i ied a HDPE
ma e ial wi h a small ac ion o Polyp opylene (PP). The powde quali y analysis e ealed a
d y low ime and g anulome y o ecycled HDPE sligh ly lowe han ha designed o o a ional
molding, which may indica e possible challenges in i s low du ing o a ional molding. I s
implica ions may be obse ed on he hickness dis ibu ion, he appea ance o su ace pinholes
and also oids on he pa . The p ocessabili y o HDPE e ealed he p esence o pin-holes a
he su ace, indica ing insu icien sin e ing o he ma e ial du ing he p ocessing cycle.
Al hough inc easing he mass and empe a u e inside he mold educed hese de ec s, he e
was an inc ease in wa ping and dis o ion o he pa s. The s udy has shown ha HDPE is
indeed iable o o a ional molding p ocess. The wo k is unde way o imp o e he quali y o
he pa s and o educe i s de ec s h ough, o example, i s mix u e wi h i gin ma e ials, and
op imiza ion o p ocessing condi ions.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
98
STUDIES ON THE REPROCESSING OF POLYETHYLENE AND POLYPROPYLENE
BLENDS
Diogo A. C uz, Ca la I. Ma ins, Júlio C. Viana
IPC/LASI – Ins i u e o Polyme s and Composi es/Associa ed Labo a o y o In elligence
Sys ems, Uni e si y o Minho, Campus de Azu ém, Guima ães, Po ugal
[email p o ec ed]; [email p o ec ed]; [email p o ec ed]
Keywo ds: Polyolephins, Blends, Recycling
2030 Sus ainable De elopmen Goals: SDG8, SDG9, SDG12, SDG13, SDG17
Polyp opylene (PP) and polye hylene (PE) domina e plas ic packaging. Thei mechanical
ecycling is used o eco e ma e ials. Howe e , gi en i s simila i ies in densi y, hey a e di icul
o sepa a e in he s eam lines. The mix u es o ma e ials wi h di e en heological
cha ac e is ics is also equen and una oidable. This s udy explo es he p ope ies o i gin
and ep ocessed PE/PP blends wi h s ong di e ence in mel low index. Ex usion-blown high-
densi y polye hylene (HDPE PCG863 om SABIC, MFI 0.35g/10 min, 190°C/2.16 kg) and PP
injec ion moulded g ade (ISPLEN PP080G2M by Repsol, MFI 20g/10 min, 230°C/2.16 kg),
we e mixed a a ying weigh pe cen ages (0, 20, 40, 60, 80, and 100% o PP in o HDPE
ma ix) and u he p ocessed by injec ion moulded o p oduce small ensile specimens. They
we e cha ac e ized o hei he mal, mechanical and mo phological p ope ies. The inc ease
o PP in o HDPE inc eased he mel low index (MFI) o he blends. Di e en ial scanning
calo ime y e ealed wo peaks co esponding o he HDPE and PP. Mel ing empe a u es
we e consis en ac oss all blends. A sligh ise in he deg ee o c ys allini y o PP and a mino
dec ease o PE was obse ed when PP con en inc ease on he blend. A ypical skin-co e
s uc u e, wi h a e y hin skin, elonga ed sphe uli es in he sub-skin egion and small
sphe uli es in he co e was ob ained. Vi gin o ep ocessed blends showed simila
mic os uc u es. SEM images show no isible phase sepa a ion be ween polyme s bu e eal
a ansi ion in ac u e su ace a ound HDPE/40% o 60% PP, om g oo ed su ace ypical o
HDPE o smoo h ac u e su ace o PP. Tensile beha iou a ies signi ican ly acco ding o he
con en o he blend: bo h ma e ials a e duc ile, howe e PP exhibi s much highe duc ili y han
HDPE. The e o e, he inc ease con en o PP on he blend enhances he blend's Young
modulus and elonga ion a b eak. Polyole ins we e success ully blended and ep ocessed,
exhibi ing sligh a ia ions in p ope ies based on composi ion. Rep ocessed blends gene ally
show up o a 20% educ ion in p ope ies compa ed o i gin coun e pa s due o he addi ional
p ocessing s ep. This opic is ele an o guide companies on he ep ocessing o hei own
ma e ials and blend and o unde s anding mechanical ecycling o polyole in was e s eams.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
99
CIRCULARITY THROUGH RECYCLING OF THERMOPLASTIC MATRIX COMPOSITES
Ca olina Cadilhe, B aian U ibe
Polo de Ino ação em Engenha ia de Políme os, Azu ém, Guima ães
[email p o ec ed], [email p o ec ed]
Keywo ds: Composi es, Recycling, Ci cula i y
2030 Sus ainable De elopmen Goals: SDG9, SDG12, SDG13
Con inuous ibe composi es wi h a he mose ing ma ix exhibi excellen chemical and
mechanical esis ance due o he ma ix c osslinking p ocess and he s uc u al ein o cemen
o he ibe s, espec i ely. Howe e , his c osslinking p ocess is i e e sible, p e en ing he
usion o he ma ix o ep ocessing and ecycling, hus hinde ing ma e ial ci cula i y. To a oid
he end-o -li e disposal o hese ma e ials in land ills o hei euse as ille s o lowe - alue
componen s, liquid he moplas ic ma ices ha e eme ged o he p ocessing o con inuous ibe
composi e ma e ials using con en ional composi e ma e ial p oduc ion me hods (e.g., RTM,
acuum-assis ed in usion, ho comp ession). Thus, he main objec i e was o e i y i ecycling
o his ma e ial was possible.
To alida e he p ocess, a lamina e consis ing o ca bon ibe s and ELIUM 188 XO liquid
he moplas ic esin, composed o polyme hyl me hac yla e, was ini ially p oduced h ough he
acuum-assis ed esin in usion p ocess. To acili a e mechanical ecycling, he ini ial lamina e
was cu in o smalle squa es and subsequen ly subjec ed o a milling machine. Once all he
c ushed ma e ial, which exhibi ed a highly he e ogeneous pa icle size dis ibu ion, was
ob ained, i was sie ed o sepa a e he di e en ibe sizes. To analyze he ma e ial p ope ies
based on he ibe size dis ibu ion, each sample's ma e ial was hen ho comp essed. Finally,
lexu al es s we e pe o med on he ini ial ma e ial and he ecycled ma e ial pla e, DSC and
FTIR es s we e conduc ed on he ini ial lamina e, c ushed ma e ial, and he comp essed pla e
o ecycled ma e ial, and densi ies we e calcula ed and compa ed. I was obse ed a dec ease
in mechanical p ope ies o he composi e ma e ial wi h he educ ion in ibe size, as expec ed,
i emained usable, unlike he mose ing ma ix composi es. Howe e , i is c ucial o conside
ha hese p ope ies depend on he pa icle size. La ge pa icle sizes, associa ed wi h highe
ibe leng hs, limi a e he ma e ial ep ocessing and compac ion, comp omising i s p ope ies
nega i ely.
Wi h his s udy, he alida ion o his ci cula i y p ocess was achie ed, con i ming he possibili y
o u ilizing he moplas ic ma ix composi e ma e ials h ough mechanical ecycling p ocesses
and subsequen ho comp ession moulding echniques.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
100
INSTITUTO PARA A SUSTENTABILIDADE E INOVAÇÃO EM
ESTRUTURAS DE ENGENHARIA
INSTITUTE FOR SUSTAINABILITY AND INNOVATION IN STRUCTURAL
ENGINEERING
ISISE
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
101
ADAPTATION OF TRADITIONAL RISK-BASED METHODOLOGY FOR SLOPES TO
PROBABILISTIC-BASED APPROACH INTEGRATING SURROGATE MODELS
Ca los Mendoza Cabanzo, Joaquim Tinoco, Helde Sousa, Má io Coelho, José
Campos e Ma os
Uni e si y o Minho, ISISE, ARISE, Depa men o Ci il Enginee ing, Guima ães, Po ugal
Keywo ds: Risk analysis, Seismic agili y cu es, Pa ame ic analysis, Railway sys ems,
Su oga e models
Due o he economic impo ance ha ailways sys ems ha e in Eu ope, i is pe inen o ensu e
good pe o mance and long- e m sa e y. Failu e o ea h s uc u es (e.g., slopes) o en esul s
in majo economic consequences, and i is a esul o he unce ain ies associa ed wi h hese
s uc u es and hei ailu e modes due o a gi en haza d. Nowadays, di e en me hodologies
can be used o assess slopes du ing ope a ional phases, bu o en he equi ed in o ma ion o
achie e a eliable assessmen may p o ide he me hodologies inapplicable, especially when
assessing mul iple asse s. This esea ch uses me hodologies ha ha e been implemen ed in
he indus y and adap s hem o a p obabilis ic app oach owa d isk assessmen , suppo ed
by he implemen a ion o k iging su oga e model, hus imp o ing i s eliabili y while
main aining he same le el o in o ma ion and compu a ional cos equi ed o i s applica ion.
A soil cu ing loca ed in he Lisbon (Po ugal) was selec ed as case s udy. Seismic agili y
cu es a e ob ained, and a mode a e isk le el is ob ained. The de i ed agili y cu es a e
based on peak g ound accele a ion and we e de eloped o di e en combina ions o
geome ic and geo echnical pa ame e s. The me hodology p o ides use ul in o ma ion o
p io i izing asse s and aking p e en i e ac ions o main ain he desi ed pe o mance o he
ailway sys em.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
102
DEVELOPMENT OF AN ECOLOGICAL THERMAL INSULATION PRODUCT FOR A
REGENERATIVE BUILDING DESIGN
Li ia Cosen ino, Rica do Ma eus, Jo ge Fe nandes
Ins i u e o Sus ainabili y and Inno a ion in S uc u al Enginee ing (ISISE), Associa e
Labo a o y Ad anced P oduc ion and In elligen Sys ems (ARISE), Azu ém, Guima ães
[email protected] ; ica doma eus@ci il.uminho.p ; jo ge. e nand[email p o ec ed]minho.p
Keywo ds: Bio-based insula ion, Regene a i e design, Low-ca bon cons uc ion
2030 Sus ainable De elopmen Goals: SDG11, SDG13, SDG15
This esea ch aims o in es iga e in asi e plan species in Po ugal o de elop a bio-based
he mal insula ion p oduc o buildings. Cu en ly, in he Eu opean Union, buildings accoun
o nea ly 40% o ene gy consump ion, a hi d o g eenhouse gas (GHG) emissions and
app oxima ely 50% o all ex ac ed ma e ials. While insula ion p oduc s a e c ucial in educing
ene gy demand, commonly used ma e ials o en ha e high embodied ene gy. Bio-based
he mal insula ion p oduc s, howe e , seques e ca bon and exhibi lowe embodied ene gy.
On he o he hand, using in asi e species biomass allows con olling hei sp ead and
es ablishes a alue chain o his esou ce. This wo k in ends o cha ac e ise he Co ade ia
selloana eed, also known as pampa g ass, o unde s and i s possibili ies as an insula ion
ma e ial.
The p ima y objec i es include de eloping and examining manu ac u ing p ocesses o
insula ion panels in compliance wi h egula o y equi emen s: one u ilising he en i e culm
sec ions and ano he employing was e om he i s in a c ushed eed agglome a e. The s udy
also aims o analyse he en i onmen al and economic li e cycle pe o mance o he new
insula ion p oduc s, compa ing hem wi h con en ional coun e pa s. Fu he mo e, i aspi es o
con ibu e o a ci cula economy by c ea ing low en i onmen al impac , minimally p ocessed,
cos -e ec i e, and biodeg adable p oduc s.
Resea ch me hods a e based on he expe imen al cha ac e isa ion o he new insula ion
p oduc s, o e alua e i hey ul il speci ic cons uc ion equi emen s, and li e cycle assessmen
o en i onmen al impac . Resul s indica e a signi ican ad an age o as -g owing bio-based
ma e ials in e ms o en i onmen al impac due o hei biogenic ca bon con en . Addi ionally,
he mal analysis e eals ha eed panels exhibi pe o mance compa able o co k as insula ion
p oduc s, possibly a ibu ed o in e nal s uc u es wi h oids apping ai .
O e all, he esea ch highligh s he po en ial o bio-based insula ion ma e ials, pa icula ly
hose de i ed om as -g owing and in asi e species. The de eloped ma e ial no only
p omo es sus ainable de elopmen bu also con ibu es o biodi e si y p ese a ion by aiding
in species con ol and main aining na i e lands. This esea ch plays a i al ole in ad ancing
sus ainable and esilien building sec o .
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
109
ANOMALY DETECTION: A TOOL TO FIND NEW PHYSICS
Mau a Ba os1, Nuno Cas o1, Ru e Ped o2, Miguel Romão1,3, Fe nando Souza1
1 Labo a ó io de Ins umen ação e Física Expe imen al de Pa ículas (LIP), Depa amen o de
Física, Escola de Ciências, Uni e sidade do Minho, Campus de Gual a , 4710-057 B aga,
Po ugal
2 Labo a ó io de Ins umen ação e Física Expe imen al de Pa ículas (LIP), A .
P o esso Gama Pin o 2, 1649-003 Lisboa, Po ugal
3 The Pala ine Cen e , Du ham Uni e si y, S ock on Road, Du ham DH1 3LE
mau a.ba os@ce n.ch; [email p o ec ed]; [email p o ec ed], m[email p o ec ed] ; [email p o ec ed]
Keywo ds: Anomaly De ec ion, Pa icle Physics, New Phenomena
2030 Sus ainable De elopmen Goals: SDG4, SDG8, SDG9
The S anda d Model (SM) o pa icle physics desc ibes he undamen al cons i uen s o isible
ma e success ully. Mul iple expe imen al esul s alida e he heo y. Howe e , he e a e
ce ain phenomena like he exis ence o da k ma e (DM) ha a e no explained by he SM.
This disc epancy mo i a es he sea ch o new physics. A he La ge Had on Collide (LHC),
an expansi e p og am is dedica ed o hese sea ches, cha ac e ised by he explo a ion o
speci ic signals and e en opologies.
Machine lea ning (ML) has become a ool ac oss di e se scien i ic domains, and Pa icle
Physics s ands as a p ime example o i s ex ensi e applica ion. O e he pas se e al yea s,
ML has played an impo an ole in inc easing analysis sensi i i y a pa icle collide s. Common
algo i hms such as G adien Boos ed Decision T ees (GBDTs) and Neu al Ne wo ks (NN) ha e
been he go- o choices in his ield. Howe e , he spo ligh is inc easingly u ning owa ds
Anomaly De ec ion (AD). Typically, AD is employed o iden i y anomalies ha de ia e
signi ican ly om es ablished pa e ns.
In pa icle physics, AD eme ges as a ool o explo e collide da a wi hou making assump ions
abou he na u e o new physics phenomena. By lea ning o econs uc S anda d Model (SM)
e en s e ec i ely, he AD algo i hm becomes a sensi i e de ec o o de ia ions, he eby
o e ing a p omising ool o he iden i ica ion o new physics signals.
This s udy goes in o a comp ehensi e examina ion o au oencode a chi ec u es, a subse o
AD me hodology. The p ima y objec i e is o ind he in ica e ela ionships be ween di e en
a chi ec u al pa ame e s and hei in luence on he sensi i i y o new signals. By sc u inizing
he inne wo kings o au oencode s, his esea ch seeks o ad ance ou unde s anding o how
hese algo i hms can be op imized o he nuanced ask o unco e ing new physics phenomena
in he ich and complex da ase s p oduced by pa icle collide s.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
110
USING MACHINE LEARNING AND ARTIFICIAL INTELLIGENCE TO SCAN BEYOND
THE STANDARD MODEL PARAMETER SPACES IN PARTICLE PHYSICS
Fe nando Ab eu Rocha de Souza1, Nuno Filipe Cas o1, Miguel Romão1, 2
1 LIP – Labo a ó io de Ins umen ação e Física Expe imen al de Pa ículas, Escola de
Ciências, Depa amen o de Física, Uni e sidade do Minho, Gual a , B aga
2 Ins i u e o Pa icle Physics Phenomenology, Du ham Uni e si y
[email p o ec ed]
Keywo ds: Pa icle Physics, A i icial In elligence, Pa ame e Spaces
2030 Sus ainable De elopmen Goals: SDG4, SDG8, SDG9
The S anda d Model (SM) o pa icle physics desc ibes he undamen al pa icles and o ces
in ou uni e se and is he mos success ul heo e ical g ound a ailable o pa icle physicis s.
Howe e , he e a e s ill se e al uncha ed e i o ies o explo e ha emain unexplained by he
SM. Among hose, he exis ence o da k ma e (DM) and neu ino masses, which demand
explana ions which go Beyond he S anda d Model (BSM) scope.
When ying o come up wi h solu ions o hese p oblems, physicis s, in gene al, p opose new
BSM heo ies which o en employ a as numbe o ee pa ame e s. In o de o assess he
alidi y o such heo ies, i is necessa y o con on hei p edic ions wi h he a ailable
expe imen al da a. Howe e , due o he la ge numbe o ee pa ame e s and expe imen al
esul s, his ask is ypically compu a ionally in ensi e and ime consuming.
We p opose a solu ion o his p oblem by adop ing sampling algo i hms which make use o
Machine Lea ning me hods in o de o imp o e he e iciency o his alida ion ask. The
e iciency and explo a o y capaci y o hese algo i hms we e es ed using he pa ame e space
o supe symme ic models and cons ained expe imen ally by he Higgs mass and he Da k
Ma e elic densi y. The esul s show a massi e imp o emen in e iciency wi h only mino
sac i ices in pa ame e space co e age.
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LABORATÓRIO DE PAISAGENS, PATRIMÓNIO E TERRITÓRIO
LANDSCAPE, HERITAGE AND TERRITORY LABORATORY
Lab2PT
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
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ANADROMOUS SEASCAPES: UNDERSTANDING MARINE SPATIAL USAGE IN
TACKLING THE IMPACT OF URBAN INFRASTRUCTURE ON MIGRATORY SPECIES.
Luís Ca los Mes inho, I o Pe ei a Oli ei a
UMinho- Escola de A qui e u a, A e & Design/Lab2PT
luismes inho@ho mail.com
Keywo ds: Human-en i onmen in e ac ions, Ma ine u baniza ion, Anad omous ishes
2030 Sus ainable De elopmen Goals: SDG14, SDG11
This wo k explo es he po en ial impac o a ma ine in as uc u e on mig a o y ma ine species
and human-en i onmen in e ac ions. I emphasizes he impo ance o unde s anding he
spa ial usage o he ma ine e i o y, which includes no only nea sho e and o sho e a eas bu
also b ackish wa e and eshwa e a eas such as i e mou hs, es ua ies, and bays. I is
sugges ed ha such an unde s anding is c ucial o managing he ex e nali ies b ough by he
in as uc u e and o mi iga ing i s impac on ma ine auna.
The in es iga ion ollows an induc i e app oach as some au ho s a gue ha indings de i ed
om pa icula cases a e capable o suppo ing he elabo a ion o gene aliza ions (Ma coni,
1993; Gil, 1999). To conduc his s udy, h ee case s udies we e analysed: he O sho e Wind
Pa k along he coas o Viana do Cas elo in Po ugal, he A slui dijk dike be ween he Wadden
Sea and he o me Sou he n Sea es ua y in he Ne he lands, and he Po o Suape in
No he n B azil. They ha e in common he po en ial o ac ual impac on mig a o y species ha
depend on he su ounding a eas whe e he in as uc u e is loca ed as well as impac s on he
popula ions ha ha e di e en so s o ela ionships wi h he ma ine auna.
The O sho e Wind Pa k case s udy showcases he impo ance o unde s anding he seascape
as expe ienced by mig a o y ishes such as sea lamp ey and shad, anad omous species ha
use bo h he sea and he i e Minho basin du ing hei li ecycle. The A slui dijk dike case s udy
illus a es how he closu e o he es ua y had an impac on mig a o y ishes ha ansi ed
be ween he es ua y and he sea, esul ing in he decline o biodi e si y and, inally, he Po
o Suape case s udy desc ibes how he loca ion and modi ica ions b ough by he Po may
ha e a con ibu ion o he ise in he sha k encoun e s along he u ban ma ine a eas o he
ci y o Reci e due o he beha iou pa e ns o he bull and ige sha ks and he cha ac e is ics
o he nea sho e in he a ea.
Taking in o conside a ion he luidi y o he wa e and he g ea mobili y o mig a o y species,
ele an insigh s a e p o ided abou he impo ance o looking a he spa ial ea u es and
e i o y usage ha exis beyond he in as uc u e loca ion. Mo eo e , i also cla i ies how
human-en i onmen in e ac ions can be a ec ed by he implemen a ion o ma ine
in as uc u e which can no only modi y he en i onmen bu also ha e unexpec ed impac s
on he mul i-species en anglemen s be ween humans and ma ine auna.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
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AUTISM AND HIGHER EDUCATION: A LOOK AT DESIGN
Thaís Eleo é io, Paula T iguei os
Mes ado em Design de P odu o e Se iço, Cou os, Guima ães
hais.eleo e [email protected]; [email protected]
Keywo ds: Uni e sal design o lea ning, ASD, Se ice logics
2030 Sus ainable De elopmen Goals: SDG4, SDG10
This essay was de eloped as pa o Semina I, augh by P o esso D . Paula T iguei os, and
p oposes o highligh he po en ial o he Uni e sal Design o Lea ning s a egy, ecognizing
he i ali y o pe sonalized and lexible app oaches o mee he di e se needs o s uden s on
he au is ic spec um. Da a om na ional esea ch highligh s he signi ican gap in educa ion
o people wi h disabili ies. Gi en he inc easing iden i ica ion o au is ic indi iduals as a esul
o g ea e access o diagnosis, i is impe a i e ha educa ional en i onmen s a e p ope ly
p epa ed o welcome hese s uden s, wi h a iew o achie ing goals ela ed o sus ainable
de elopmen , such as hose s ipula ed in Goals 4 and 10.
The me hodology adop ed in his s udy is quali a i e, based on a li e a u e e iew, analysis o
esea ch on adap a ions in highe educa ion o au is ic people and he collec ion o epo s
h ough di e en o ma s, such as podcas s, ideos and pe sonal messages. These epo s
p o ide an in-dep h iew o he expe iences o indi iduals on he au is ic spec um in he
academic en i onmen . As a guide, he conclusions p esen ed in Jenni e Sa e 's a icle
en i led "Au ism and Accommoda ions in Highe Educa ion: Insigh s om he Au ism
Communi y" a e explo ed. This e e ence o e s a aluable amewo k o con ex ualizing he
p ac ices and challenges associa ed wi h he inclusion o au is ic people in highe educa ion.
Uni e sal Design o Lea ning is highligh ed in Jenni e Sa e 's a icle as a po en ial
me hodology o be used in educa ional en i onmen s and, by explo ing he e ec i eness o
Uni e sal Design o Lea ning in p omo ing inclusi e educa ional en i onmen s, we ques ion i
i alone is enough o p omo e awa eness and i adap ing educa ional ma e ials is enough o
gua an ee equi y in hese spaces. Faced wi h his ques ion, we in oduced se ice logic om
an inclusi e pe spec i e as an app oach wi h he po en ial o conside all in e ac ions and
agen s as co-c ea o s o solu ions in he educa ional en i onmen , in addi ion o being able o
pu in o p ac ice he UDL applica ion model p oposed by Schwanke, Smi h and Edybu n.
This essay concludes by highligh ing he impo ance o a holis ic app oach o p omo ing social
inclusion, in ol ing awa eness, educa ional and a chi ec u al adap a ion o ensu e equi y o
all s uden s. Fu he mo e, gi en he inc easing p e alence o au ism diagnoses, i is c ucial o
conduc u he esea ch in his a ea, wi h a pa icula ocus on he adul popula ion, o en
neglec ed in la ge in es iga ions.
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LABORATÓRIO DE SOFTWARE CONFIÁVEL
HIGH-ASSURANCE SOFTWARE LABORATORY
HasLab
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
115
HOW SUSTAINABLE IS YOUR PROGRAMMING LANGUAGE? ANALYSING THE
IMPACT OF POWERCAP ON ENERGY EFFICIENCY OF PROGRAMMING
LANGUAGES
Simão Cunha, Luís Sil a, João Sa ai a
HasLab, Uni e si y o Minho, Gual a , B aga
[email p o ec ed]; [email p o ec ed]; [email p o ec ed]
Keywo ds: G een So wa e, P og amming Languages, RAPL
2030 Sus ainable De elopmen Goals: SDG9, SDG12, SDG17
This abs ac p o ides a concise summa y o an in-dep h in es iga ion in o he ene gy
e iciency o so ing algo i hms implemen ed in a ious p og amming languages, employing
s a is ical analysis echniques and mul i-c i e ia op imiza ion me hods.
The s udy conside s pa ame e s such as de elopmen cos , execu ion ime, ene gy
consump ion, co es’ empe a u e, and memo y consump ion. We u ilize he Powe Cap lib a y
o moni o and con ol p ocesso powe consump ion o enhanced ene gy e iciency
assessmen . To measu e he ene gy consump ion o he so ing algo i hms implemen ed in all
p og amming languages unde conside a ion, we employ he Running A e age Powe Limi ing
(RAPL) in e ace om In el.
The esea ch encompasses a ho ough examina ion o h ee so ing algo i hms ac oss hi een
p og amming languages. Quick So demons a ed supe io pe o mance in execu ion ime,
especially unde en o ced powe caps. No ably, he p og amming language C eme ged as he
mos op imal choice, showcasing supe io execu ion ime and powe e iciency. In con as ,
Selec ion So exhibi ed weake pe o mance unde powe limi a ions, and Ko lin demons a ed
compa a i ely lowe e iciency in bo h execu ion ime and powe me ics.
The s udy's analysis p o ides p o ound insigh s in o he ene gy e iciency o so ing algo i hms
ac oss p og amming languages, highligh ing he signi icance o pa ame e s on algo i hm
e alua ion and language anking. Mul i-c i e ia op imiza ion emphasizes he c i ical ole o ime
and pe o mance in he assessmen o so ing algo i hms, unde sco ing he e iciency
a ia ions among p og amming languages.
In conclusion, he s udy o e s aluable insigh s in o he ene gy e iciency o so ing algo i hms,
emphasizing he necessi y o language-speci ic op imiza ions o ene gy-e icien so wa e
solu ions. The combined use o s a is ical analysis and mul i-c i e ia op imiza ion p o ides a
comp ehensi e pe spec i e on so ing algo i hm pe o mance, acili a ing in o med decision-
making in ene gy-e icien so wa e de elopmen . The Powe Cap lib a y's e ec i eness in
managing and op imizing p ocesso powe consump ion con ibu es o a mo e sus ainable
compu ing en i onmen . O e all, his s udy adds a nuanced pe spec i e by speci ically
e alua ing h ee so ing algo i hms ac oss hi een p og amming languages, elucida ing he
impac o powe limi a ions on hei pe o mance.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
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NÚCLEO DE INVESTIGAÇÃO EM POLÍTICAS ECONÓMICAS
CENTRE FOR RESEARCH IN ECONOMICS AND MANAGEMENT
NIPE
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
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THE PROMOTION OF SUSTAINABILITY IN HIGHER EDUCATION INSTITUTIONS:
KEY FACTORS TO ADOPT FROM THE ORGANIZATIONAL PERSPECTIVE
Enzo Fe nandes, Ana Ca alho
School o Economics and Managemen , Gual a , B aga
[email p o ec ed]; [email p o ec ed],p
Keywo ds: Sus ainabili y, Highe Educa ion Ins i u ions, De elopmen
2030 Sus ainable De elopmen Goals: SDG4, SDG11, SDG12
This abs ac ocuses on p esen ing concep s and ac ions ha Highe Educa ion Ins i u ions
(HEIs) mus adop o a concise implemen a ion o Sus ainabili y guidelines on an
o ganiza ional le el. Since HEIs pu sue a signi ican ole in ci il socie y o ming indi iduals on
an educa ional and ci il le el wi h he ansmission o ideas, he s eng hening o Sus ainable
De elopmen is a co e ac o ha mus be s imula ed by hose educa ional o ganiza ions.
Sus ainabili y as an academic s udy a ea has been hea ily in luenced by he s a us quo ha
ou globalized ci il socie y is cu en ly acing. The excessi e p oduc ion and consump ion o
goods led humans o e hink and e alua e hei li es yles, which in luenced di e en
al e na i es ha can c ea e a posi i e impac on a socie al le el. In his con ex , i makes sense
ha HEIs inc ease hei engagemen and p omo ion o sus ainable ansi ion.
Fu he mo e, he sus ainabili y commi men o HEIs is a ac o ha eaches di e en di ec ions
and eme ges wi h c ea i e solu ions. The implemen a ion o sus ainable goals p oposed by he
au ho ocuses on opics such as digi aliza ion, esponsible consump ion, and awa eness
p omo ion.
E en digi aliza ion isn’ obli ious o HEIs, he e is a conside able numbe o in e nal p ocesses
ha should be e alua ed o maximize he se ices on an o ganiza ional le el ha s imula e he
sus ainable ansi ion a he same ime. The e is an u gen necessi y o e hinking and
unde s anding ha digi aliza ion imp o es he quali y o se ices and p ocesses’
ans o ma ion can be implemen ed easie han i appea s. Is pape necessa y o some
p ocesses? How does disloca ion o physical acili ies a ec he ci y ha hose HEIs a e in?
Mo ing on, esponsible consump ion will become a eali y i he HEIs campuses p omo e i in
di ec o indi ec ways. Which a e he ene gy sou ces o he campus? Does he campus ha e
e icien ecycling acili ies? How do he campuses manage ood was e? Some o hose
examples a e ac o s ha e en i hey look ob ious, some uni e si ies s ill s uggle o manage
p ope ly.
Finally, he awa eness p omo ion mus be done wi h clea communica ion and wi h s uden
pa icipa ion. Digi aliza ion is also a co e esou ce able o s imula e he impo ance o
sus ainabili y.
To conclude, he engagemen o HEIs on sus ainable de elopmen is some hing c ucial and
ha is possible o be exp essed e o lessly. The know-how om pionee ing HEIs on
sus ainabili y, maximiza ion o digi aliza ion, he p omo ion o engagemen and awa eness, and
inally he e alua ion o he cu en se ice design o he o ganiza ion is always necessa y o
boos HEI’s sus ainable ansi ion, ollowing he 2030 Sus ainable De elopmen Goals.
UMinho Resea ch & Inno a ion Open Days, 30-31 Janua y 2024
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FULL-TIME EDUCATION: ASSESSMENT OF THE IMPACT ON LEARNING OF THE
BRAZILIAN PROGRAM NOVO MAIS EDUCAÇÃO
Luiz Felipe Magnago Blulm1, Ana Ca olina Giube i2, João Ca los Ce ejei a
Sil a1
1 Uni e si y o Minho, Gual a , B aga
1 Fede al Uni e si y o Espí i o San o, Ja dim da Penha, Vi ó ia - ES
2 Fede al Uni e si y o Espí i o San o, Ja dim da Penha, Vi ó ia – ES
[email p o ec ed]; ana.gi[email p o ec ed]; joao.[email p o ec ed]
Keywo ds: Full- ime Educa ion, Di e ence-in-Di e ences, Lea ning
2030 Sus ainable De elopmen Goals: SDG4
Al hough he e is no consensus on he e ec i eness o ull- ime educa ion on lea ning, se e al
La in Ame ican coun ies ha e de eloped p og ams o ex end school hou s o achie e a highe
le el o s uden pe o mance. In B azil, he ede al go e nmen implemen ed wo policies o
inc ease school hou s: he Mais Educação P og am (PME), om 2008 o 2017, and he No o
Mais Educação P og am (PNME), in 2018 and 2019. The e o e, his a icle e alua es he
impac o PNME on s uden lea ning and discussion on he e ec i eness o he PNME design
in ela ion o he p e ious policy, PME.
We used o icial da a om he B azilian go e nmen and he me hodology combined Di e ence
in Di e ences wi h p opensi y sco e ma ching o e alua e s uden s' g ades in ma hema ics and
languages. Al hough ecen de elopmen s show ha he TWFE is biased, o e alua e policies
ha a e implemen ed o e a pe iod, he PNME was implemen ed all a once, making his case
a classic 2x2, allowing o he adop ion o he TWFE.
Fo he ini ial yea s o p ima y educa ion, he esul s show a posi i e impac on lea ning, bu
o he inal yea s he esul s we e ambiguous: a null e ec on language s uden s' g ades and
a nega i e impac on ma hema ics es esul s. A esul consis en wi h he li e a u e ha poin s
o he cumula i e e ec o lea ning. Howe e , hese esul s we e mo e p omising han hose
o i s p edecesso , he PME, which can be a ibu ed o he design o he PNME being mo e
ocused on expanding he hou s o language and ma hema ics lea ning. Ou esul s indica e
ha he way in which he in eg al educa ion policy is designed can di ec ly impac he esul s
ob ained in s uden lea ning. The design o he PNME is ocused on educa ion as measu ed
by na ional es s, while he PME had no such ocus.
This esea ch con ibu es new e idence on he e ec i eness o comp ehensi e educa ion.
Fu he mo e, i b ings in o discussion he ele ance o an adequa e design o ob ain he
expec ed esul s. We sugges ha u u e s udies compa e o he policies wi h di e en designs
o check whe he he e a e consis encies be ween he designs ha ob ained posi i e lea ning
esul s.
