390
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE “MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
MAIN GROUPS OF BIOLOGICALLY ACTIVE SUBSTANCES OF CHICKWEED
(STELLARIA MEDIA L.) AND THEIR PHARMACOLOGICAL SIGNIFICANCE
Saipiye a B.S.
Sayako a G.M.
Kazakh Na ional Medical Uni e si y named a e S.D. As endiya o , Alma y,
Republic o Kazakhs an
e-mail: [email p o ec ed] 8-707-716-38-02
h ps://doi.o g/10.5281/zenodo.17339453
Rele ance: Chickweed (S ella ia media L.) is a widesp ead annual plan in he
Ca yophyllaceae amily, possessing a ich chemical composi ion. In e es in his species s ems om
he p esence o a ious biologically ac i e subs ances, which de e mine i s pha macological ac i i y
and po en ial o use in he bal medicine. Howe e , despi e his, he e a e no medica ions based on
chickweed (S ella ia media L.). S udying i s p ope ies would expand he pha maceu ical ma ke .
S udy Objec i e. To analyze li e a u e da a on he chemical composi ion o chickweed, o
de e mine i s pha macological ac ion, and o iden i y he main g oups o biologically ac i e
subs ances.
Ma e ials and Me hods. In e na ional li e a y sou ces, including da a on he phy ochemical
composi ion and pha macological ac i i y o chickweed componen s, we e used. A sys ema ic
analysis and syn hesis o scien i ic in o ma ion was used. Pa icula a en ion was paid o s udies
de o ed o he s udy o la onoids, saponins, phenolic acids, and i amins.
S udy Resul s. Based on a e iew o he li e a u e, i was es ablished ha chickweed (S ella ia
media L.) con ains a wide ange o biologically ac i e subs ances. The mos signi ican include
la onoids ( u in, que ce in, apigenin), saponins, phenolic acids (chlo ogenic, ca eic, e ulic), as well
as i amins C and E and ca o enoids. The la onoids con ained in he plan exhibi p onounced
an ioxidan ac i i y, helping o neu alize ee adicals, educe in lamma ion, and s eng hen capilla y
walls. Saponins exhibi immunomodula o y and an i-in lamma o y e ec s and also in luence lipid
me abolism. Phenolic acids inhibi lipid pe oxida ion, p o ec ing cells om oxida i e s ess. The
i amin complex o chickweed enhances i s o e all onic e ec .
E idence has also been ound o he po en ial an imic obial, diu e ic, and wound-healing
ac i i y o he plan 's ex ac s, con i ming i s sui abili y o use in phy o he apeu ic o mula ions.
Addi ionally, li e a u e p o ides in o ma ion on hypoglycemic and hypolipidemic e ec s, opening up
po en ial o he use o chickweed in me abolic diso de s. The combina ion o hese p ope ies allows
his plan o be conside ed a sou ce o na u al an ioxidan s and complex biologically ac i e
compounds ha may be use ul in he de elopmen o new d ugs and die a y supplemen s.
Conclusion. Thus, chickweed (S ella ia Media L.) is a p omising sou ce o biologically ac i e
subs ances wi h a wide ange o pha macological p ope ies. Fu he esea ch aimed a s anda dizing
he con en o ac i e componen s and assessing hei bioa ailabili y is necessa y o subs an ia e
medical use and de elop e ec i e dosage o ms based on his plan .
