Volume 1 | Issue 3 | 1 o 3
Nu P ima y Ca e, 2017
E ec i eness o Cell Sa e in Val e Su ge y and Co ona y Su ge y
Resea ch A icle
Hea Su ge y Se ice o Vi gen Maca ena Uni e si y Hospi al,
Facul y o Nu sing, Physio he apy and Podia y o he Uni e si y
o Se ille, Spain.
*Co espondance:
Manuel Luque Oli e os, PhD, RN. Hea Su ge y Se ice o Vi gen
Maca ena Uni e si y Hospi al, Facul y o Nu sing, Physio he apy
and Podia y o he Uni e si y o Se ille, Spain, E-mail: mluque5@
us.es.
Recei ed: 12 July 2017; Accep ed: 07 Augus 2017
Manuel Luque Oli e os
Nu sing & P ima y Ca e
ABSTRACT
In oduc ion: The cell sa e (CR) is an al e na i e o blood ans usion. I is used in su gical p ocedu es ha
lose la ge blood concen a es, such as ca diac su ge y unde an ex aco po eal ci cui . Also CR is used in hea
ope a ions whe e hey p edic majo blood loss, such as co ona y and al e su ge y, so we ask he esea ch ques ion;
Is RC mo e e ec i e in Company? Co ona y wi h espec o he Company. Val e o ice e sa? The objec i e o
his s udy was o e alua e he e icacy o CR in educing ans usion equi emen s in pa ien s unde going co ona y
and al ula su ge y.
Me hodology: Desc ip i e, longi udinal, p ospec i e and obse a ional s udy, whe e wo coho s o pa ien s we e
es ablished: Co ona y g oup (CG), al ula g oup (GV), bo h g oups we e used CR. The s udy popula ion is hose
who unde wen co ona y and al ula su ge y, whose sample a ends 30 pa ien s, 15 o each g oup. Pe iod o
s udy 1-31 Oc obe 2014. Consen In o med o pa ien and E hics Commi ee o ou hospi al. SPSS s a is ical
package 18.
Resul s: Haemoglobin / Haema oc i : GC, 10.2g /dl - 30.02%. GV, 9.8g /dl - 28.16%. Au ologous blood ans usion:
GC, 95.1%. GV, 89.9%. p=0.37. Allogeneic blood ans usion: GC, 10.1% GV, 4.9%
Conclusions: The cell sa e is e ec i e in he wo su gical in e en ions s udied, and he e a e no s a is ically
signi ican di e ences. The e o e, i s use as a measu e o he educ ion o allogeneic blood ans usion is
ecommended.
ISSN 2639-9474
Resea ch A icle
Ci a ion: Manuel Luque Oli e os. E ec i eness o Cell Sa e in Val e Su ge y and Co ona y Su ge y. Nu P ima y Ca e. 2017; 1(3): 1-3.
Keywo ds
Nu sing, Hea su ge y, Au o ans usion.
In oduc ion
The Clinical P ac ice Guidelines o he Spanish Socie y o
Ca diolog [1] indica e ha a measu e o sa ing blood o allogeneic,
dono and ecipien blood ans usions a e di e en , would be
au o ans usion o ans usion o au ologous blood.
When alking abou au ologous blood ans usion, we mean ha he
dono and he pa ien a e he same pe son, which sol es impo an
p oblems associa ed wi h allogeneic blood ans usion, such as he
elimina ion o possible immunological complica ions, he isk o
T ansmission o in ec ious diseases o dec eases he consump ion
o dona ed blood uni s o gene al use [2].
A s a egy o pe o m au ologous blood ans usion in pa ien s
unde going ca diac su ge y unde ca diopulmona y bypass is
cu en ly being used. I is called he cell sa e (CR). The CR is
an elec onic de ice ha is esponsible o eco e ing he pa ien 's
blood om he su gical ield, as well as he esidual olume o
he ex aco po eal ci cula ion pump ci cui a e ca diopulmona y
bypass, in o de o ake ad an age o he maximum amoun o
Blood a ailable, ha a e a p ocessing cycle a olume o ed blood
cells is ob ained which is he one ha is ein used o he pa ien [3].
I is a undamen al pilla in he s a egies o al e na i e allogeneic
blood ans usion, which always aking in o accoun he ue
Volume 1 | Issue 3 | 2 o 3Nu P ima y Ca e, 2017
indica ions o he same, a e e y e ec i e, since he keys o
success in i s managemen , is he mul i ac o ial app oach, since
he combina ion o se e al echniques is mo e e ec i e han each
o hem sepa a ely [4].
I is well known ha he su gical ea men o co ona y disease
will be di ec ed o e ascula iza ion, while al e su ge y will
be o eplacemen o al e eplacemen , wo di e en su gical
p ocedu es ha a ec he hea and whe e he CR is used wi h
a medium. We a e wonde ing; Is he CR in co ona y su ge y
mo e e icien han al ula su ge y o ice e sa? To answe
his ques ion, we se he ollowing objec i e: To e alua e he
e icacy o he use o he CR in educing ans usion equi emen s
in pa ien s unde going su ge y o al ula and co ona y su ge y
unde ex aco po eal ci cula ion.
Ma e ial and Me hod
This is a desc ip i e, longi udinal p ospec i e and obse a ional
s udy, whe e wo coho s o pa ien s a e es ablished: Co ona y
g oup, pa ien s unde going co ona y pa hology and using he
cell sa e . Val ula g oup, hose pa ien s ope a ed on o al ula
pa hology and using he cell sa e .
The s udy popula ion was all pa ien s unde going ca diac su ge y
unde ex aco po eal ci cula ion a he UGC o he Ca dio ascula
Su ge y Se ice o he Vi gen Maca ena Uni e si y Hospi al.
The sample consis ed o 30 pa ien s, o which 15 co esponded o
he co ona y g oup and he emainde o he al ula g oup, wi hin
he pe iod om 01 o 31 Oc obe 2014. The inclusion c i e ia
a e pa ien s: Scheduled o a su gical in e en ion o Val ula
and co ona y su ge y whe e he cellula ecupe a o is used. To
olun a ily accep o pa icipa e in said s udy. On he o he hand,
we excluded: Eme gency esusci a ion because hese pa ien s
p esen al e a ions in he hemoglobin and hema oc i numbe s,
which may mask he esul s o he collec ion o he a iables.
In e en ions o al ula o co ona y su ge y ha do no use he
cell sa e o an ex aco po eal ci cui . Those who do no wan o
pa icipa e in he s udy.
The a iables analyzed in bo h g oups we e: Socio-demog aphic
as age (exp essed in yea s), sex/gende , weigh (exp essed in
kg) and heigh (exp essed in cm). And, clinical a iables such as
haemoglobin (exp essed in g/dl), haema oc i (exp essed in %),
numbe o au ologous blood ans usions ecei ed and numbe
o allogeneic blood ans usions ecei ed. All o he a iables
desc ibed we e analyzed sepa a ely in he co ona y g oup and in
he al ula g oup wi hin he ope a ing oom o ca dio ascula
su ge y o ou hospi al and a e he end o he su gical in e en ion.
All pa ien s who pa icipa ed in ou s udy and he E hics and
Resea ch Commi ee o ou hospi al we e asked o in o med
consen . The da a we e subjec ed o s a is ical analysis using he
s a is ical package SPPS e sion 18.0 o Windows, using he
Pea son Chi-Squa e o compa e he s a is ical a iables, and o
he con inuous a iables he S uden 's T was used o de e mine i
he e we e di e ences o no s a is ically signi ican . The mean
and s anda d de ia ion alues we e also calcula ed by accep ing a
con idence le el o p=0.05.
Resul s
Socio-demog aphic a iables
• Age: In he co ona y g oup he mean was 65.95 yea s wi h a
s anda d de ia ion o 9.70 yea s. In con as , in he al ula
g oup i was 66, 38 yea s wi h a s anda d de ia ion o 9.35
yea s. S uden , p = 0.718.
• Sex/gende : In he co ona y g oup, 89.4% we e male and
10.6% emale e sus 80.6% male and 19.4% emale om he
al ula g oup. Chi-Squa e, p = 0.092.
• Weigh : In he co ona y g oup, he mean was 65.8 kg e sus
74.2 kg in he con ol g oup. Chi-Squa e, p = 0.131.
• Size: In he co ona y g oup, he mean was 159.1 cm e sus
he 160.8 cm o he al ula g oup.
Clinical a iables
• Haemoglobin and haema oc i : In he co ona y g oup he
mean hemoglobin igu e was 10.2 g/dl wi h a hema oc i o
30.02%. In he al ula g oup, he mean hemoglobin le el
was 9.8 g/dl and 28.16% hema oc i . p=0,23.
• Numbe o au ologous blood: Pa ien s who we e ans used
a e comple ion o su ge y wi h blood eco e ed om he
cellula eco e y we e 95.1% in he co ona y g oup and
89.9% in he al ula g oup. Chi-Squa e, p= 0.37.
• Allogeneic blood numbe : Pa ien s who ecei ed allogeneic
blood a e comple ion o su ge y in he co ona y g oup we e
10.1% in he co ona y g oup and 4.9% in he al ula g oup.
Discussion
A he end o he su gical in e en ion, we did no ind s a is ically
signi ican di e ences be ween he co ona y g oup and he al ula
g oup, on he analy ical pa ame e s, haemoglobin and haema oc i .
Al hough he mean hemoglobin and hema oc i be ween he wo
g oups is conside ed low conside ing he alues p oposed by he
Wo ld Heal h O ganiza ion [5], o de ine anemia, bu in he con ex
o ca diac su ge y unde ex aco po eal ci cula ion, hese alues
a e conside ed no mal by he T ea men and e e als su e ed by
he pa ien 's blood.
Rega ding he numbe o au ologous blood ans usions be ween
he co ona y g oup and he al ula g oup, he e a e no s a is ically
signi ican di e ences, bu he numbe o allogeneic blood ecei ed
be ween he wo g oups is s iking, being highe in he co ona y
g oup. I he e a e s a is ically signi ican di e ences.
Howe e , hese di e ences can be a ibu ed o he ac ha
in he co ona y g oup he e is a longe ime o exposu e o he
ex aco po eal machine o he ime spen in he by-pass, and
he e is no di ec ela ionship wi h he use o no o he cellula
ecupe a o .
Conclusions
The cell sa e is e ec i e in he wo su gical in e en ions s udied,
Volume 1 | Issue 3 | 3 o 3Nu P ima y Ca e, 2017
© 2017 Oli e os ML. This a icle is dis ibu ed unde he e ms o he C ea i e Commons A ibu ion 4.0 In e na ional License
and he e a e no s a is ically signi ican di e ences. The e o e, i s
use as a measu e o he educ ion o allogeneic blood ans usion
is ecommended.
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clínica de la sociedad española de ca diología en el pos
ope ado de ca diopa ía congéni a. Re . Esp. Ca diol. 2000.
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2. Rendón FG, He nández M, Fuen es V, e al. In e ención
qui ú gica sin sang e: e i ando ans usiones. Medicina
Un e si a ia. 2007; 9: 186-197.
3. Rohen JW. Topog aphische ana omies dee b us o gane. In:
opog aphische ana omies. Scha aue e lag S u ga . New
Yo k .1992; 9: 311.
4. Ve ga a JC. Sang ado pos ope a o io en ci ugía ca diaca.
2012; 01: 107.
5. Ca mel R. Anemia and aging: an o e iew o clinical,
diagnos ic and biological segues. Blood Re . 2001; 15: 9-18.
