CHARACTERISTICS AND TECHNOLOGY OF OBTAINING DRY EXTRACT OF COMMON RASPBERRY (RUBUS IDAEUS), GROWING IN SOUTHERN KAZAKHSTAN

84 Volume 5, Issue 10: Special Issue (EJAR) ISSN: 2181-2020 MPHAPP THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL CONFERENCE “MODERN PHARMACEUTICS: ACTUAL PROBLEMS AND PROSPECTS” TASHKENT, OCTOBER 17, 2025 in-academy.uz CHARACTERISTICS AND TECHNOLOGY OF OBTAINING DRY EXTRACT OF COMMON RASPBERRY (RUBUS IDAEUS), GROWING IN SOUTHERN KAZAKHSTAN Turebekova G. A.1 Daurenbekov K. N.2 JSC South Kazakhstan Medical Academy, Shymkent, Republic of Kazakhstan e-mail: [email protected] https://doi.org/10.5281/zenodo.17321560 Relevance: Common raspberry (Rubus Raspberry (idaeus) is the most common berry bush, possessing high nutritional and biologically active properties. Southern Kazakhstan, with its diverse climate and rich flora, offers unique opportunities for studying and using raspberries. Objective: to develop a technology for obtaining a dry extract from common raspberry leaves, preserving the high content of biologically active substances and obtaining a high-quality product for use in pharmaceuticals. Research methods: 1. Collection and preparation of raw materials: Red raspberry leaves were collected during the growing season, when they contain the maximum amount of biologically active substances. The optimal collection period is June-July. 2. Drying the leaves: To preserve the maximum amount of biologically active substances, gentle drying was used at a temperature no higher than 40-50°C. Drying duration : 6-8 hours, until the raw material moisture content reached less than 10%. 3. Grinding: The dried leaves were ground to a powder with a particle size of 0.5-1 mm. 4. Extraction: A 70% ethanol solution was used, as it is considered the most suitable solvent for extracting flavonoids , tannins, and organic acids. The raw material to solvent ratio was 1:10 (one part dry raw material to 10 parts solvent). Extraction method: The raw material was infused at room temperature for 24-48 hours with periodic stirring. Extraction was carried out under reflux at 40-60°C for 2-4 hours. This method accelerates the process and increases the yield of active substances. 5. Extract purification: The resulting solution was filtered to remove solid particles. Paper and membrane filters were used. The purified extract was evaporated on a rotary evaporator at a temperature no higher than 40°C until the volume was reduced by 5-10 times. 6. Obtaining a dry extract: the dry extract is a light to dark green powder with a characteristic odor and taste. Moisture content is no more than 5%. 7. The content of biologically active substances was determined using spectrophotometric and chromatographic methods. Research results: using this technology, we obtained a high-quality dry extract of common raspberry, which will retain its medicinal properties (Table 1): Table 1. Results of quantitative analysis Flavonoids 0.4% Tannins from 2-5% Vitamin C (ascorbic acid) 0.03% -0.1% Vitamin E (tocopherol) 0.001-0.002% B vitamins (including B1, B2, B3, B6). 0.001-0.01% Conclusions: The developed technology for producing a dry extract from common raspberry leaves preserves the high content of biologically active substances, such as flavonoids , tannins, and 85 Volume 5, Issue 10: Special Issue (EJAR) ISSN: 2181-2020 MPHAPP THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL CONFERENCE “MODERN PHARMACEUTICS: ACTUAL PROBLEMS AND PROSPECTS” TASHKENT, OCTOBER 17, 2025 in-academy.uz organic acids. The dry extract can be used as an ingredient in pharmaceuticals and dietary supplements.