MAKING A TINCTURE FROM WILD WATERMELON ROOT AND ITS USE FOR STROKES

159 Volume 5, Issue 10: Special Issue (EJAR) ISSN: 2181-2020 MPHAPP THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL CONFERENCE “MODERN PHARMACEUTICS: ACTUAL PROBLEMS AND PROSPECTS” TASHKENT, OCTOBER 17, 2025 in-academy.uz MAKING A TINCTURE FROM WILD WATERMELON ROOT AND ITS USE FOR STROKES Sandybaeva Z.Kh. Ashirova G.Sh. Osh State University, Osh, Kyrgyzstan, e - mail : zsandybaeva @ oshsu . kg Tel.: +996 555022099 https://doi.org/10.5281/zenodo.17328657 Actuality: Cardiovascular diseases, particularly stroke, are widespread among the population, independently of age. Therefore, a pressing task is the in-depth scientific study and development of homeopathic remedies with a pronounced pharmacological effect and low toxicity from plants growing in Kyrgyzstan and used in folk medicine. One such promising remedy is a tincture of wild watermelon root ( Citrullus Colocynthis (colocynthis ). The plant has anti-inflammatory, diuretic, and neuroprotective properties.Here below is a method for preparing an alcohol tincture and a discussion of its potential use in complex therapy and rehabilitation after stroke. The aim of the study was to prepare a tincture from the root of wild watermelon. Introduction: Wild Watermelon (Citrullus Colocynthis is a plant of the Cucurbitaceae family, known for its medicinal properties. The root of wild watermelon contains a complex of biologically active compounds (cucurbitacins, flavonoids), which have a potential therapeutic effect in the context of the prevention and treatment of the consequences of stroke, including neuroprotective , antioxidant, and anti-inflammatory effects [6,7,9]. Materials and methods: graduated cylinder, glass container with a sealed lid (≥700 ml), gauze, dark glass bottle, alcohol maceration and extraction. To prepare the tincture, add 50 g of crushed root to 500 ml of 70% alcohol, let it steep for 14 days in the dark, and then filter. The finished product is stored in a dark glass container. Results: We obtained 500 ml of tincture from the root of wild watermelon, dark yellow in color. Conclusions: Wild watermelon root tincture is of scientific interest as a potential treatment for comprehensive rehabilitation after stroke. Preliminary data indicate a positive effect on cognitive function and reduced swelling. However, further in-depth pharmacological and clinical studies are needed before it can be implemented into clinical practice.