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snRNAseq of olfactory epithelium with AAV serotypes for transduction of olfactory sensory neurons in Mus musculus

Belfort, Benjamin; Jia, Johnathan; Garza, Alexandra; Insalaco, Anthony; McGinnis, John; Pekarek, Brandon; Ortiz-Guzman, Joshua; Tepe, Burak; Chen, Hu; Liu, Zhandong; Arenkiel, Benjamin

Abstract

This Zenodo deposit contains a publicly available description of the Dataset: Title: "snRNAseq of olfactory epithelium with AAV serotypes for transduction of olfactory sensory neurons in Mus musculus". Description: Single-nucleus RNA sequencing data of 4 mice, each inoculated with 4 AAV serotypes. The mice were all male and 8-10 weeks of age at when olfactory epithelium tissue was harvested. Samples were paired-end sequences using v3.1 – Dual Index using Illumina Novaseq 6000 sequencer. This dataset is made available to researchers via the ASAP CRN Cloud: cloud.parkinsonsroadmap.org. Instructions for how to request access can be found in the User Manual. This research was funded by the Aligning Science Across Parkinson's Collaborative Research Network (ASAP CRN), through the Michael J. Fox Foundation for Parkinson's Research (MJFF). This Zenodo deposit was created by the ASAP CRN Cloud staff on behalf of the dataset authors. It provides a citable reference for a CRN Cloud Dataset

Full text

This Zenodo deposit contains a publicly available description of the Dataset: "snRNAseq of olfactory epithelium with AAV serotypes for transduction of olfactory sensory neurons in Mus musculus". Dataset Description: Single-nucleus RNA sequencing data of 4 mice, each inoculated with 4 AAV serotypes. The mice were all male and 8-10 weeks of age at when olfactory epithelium tissue was harvested. Samples were paired-end sequences using v3.1 – Dual Index using Illumina Novaseq 6000 sequencer. Authors: • Belfort, Benjamin; ORCID:0000-0002-2866-5763; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX. • Jia, Johnathan; ORCID:0000-0001-7466-8589; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX. • Garza, Alexandra; ORCID:0000-0003-3288-4237; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX. • Insalaco, Anthony; ORCID:0009-0005-7761-0506; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX. • McGinnis, John; ORCID:0009-0003-5669-5913; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX. • Pekarek, Brandon; ORCID:0000-0001-8785-4196; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX. • Ortiz-Guzman, Joshua; ORCID:0000-0002-7000-394X; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX. • Tepe, Burak; ORCID:0000-0003-4371-2502; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX. • Chen, Hu; ORCID:0000-0001-5472-7158; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX. • Liu, Zhandong; ORCID:0000-0002-7608-0831; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX. • Arenkiel, Benjamin; ORCID:0000-0001-9047-2420; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX. ASAP Team: Schlossmacher Dataset Name: schlossmacher-mouse-sn-rnaseq-osn-aav-transd, v1.0 Principal Investigator: Benjamin A Arenkiel, [email protected] Dataset Submitter: Johnathan Jia, [email protected] Publication DOI: 10.1101/2024.09.26.615247 Grant IDs: ['10000400'] ASAP Lab: Arenkiel/Liu Lab ASAP Project: Comparative analysis of AAV serotypes for transduction of olfactory sensory neurons Project Description: snRNAseq of mouse olfactory epithelium to identify best AAV serotype for transduction of olfactory sensory neurons. Submission Date: 2025-10-03 This dataset is made available to researchers via the ASAP CRN Cloud: cloud.parkinsonsroadmap.org. Instructions for how to request access can be found in the User Manual. This research was funded by the Aligning Science Across Parkinson's Collaborative Research Network (ASAP CRN), through the Michael J. Fox Foundation for Parkinson's Research (MJFF). This Zenodo deposit was created by the ASAP CRN Cloud staff on behalf of the dataset authors. It provides a citable reference for a CRN Cloud Dataset