EVALUATION STUDY OF POLYPHENOLS IN AYURVEDIC DIETARY SUPPLEMENTS AND YOGA THERAPY ON MIDDLE-AGED WOMEN WITH TYPE II DIABETES

International Journal of Pharmaceutical Science and Health Care Volume 15, Number 6, 2025 Available online on http://www.rspublication.com/ijphc/index.html ISSN 2249 – 5738 DOI: 10.5281/zenodo.17848453 Original Article ©2025 RS Publication, [email protected] 121 EVALUATION STUDY OF POLYPHENOLS IN AYURVEDIC DIETARY SUPPLEMENTS AND YOGA THERAPY ON MIDDLE-AGED WOMEN WITH TYPE II DIABETES AUTHORS AND CONTRIBUTORS Dr C.G. Vishnu Kumar, M.Sc. (Yoga & Naturopathy), M.Phil. (Yoga), PhD (Yoga), Email: [email protected]om *Corresponding Author: *Prof. Dr. Ashalatha, *Corresponding Author, Professor and Wellness Counsellor, Hyderabad Institute of Technology and Management (HITAM) *Corresponding Author: Professor Dr S. Siva Prasad Rao, PhD, Vice Chancellor, Vedic Wellness University, Florida, USA, sivaprasadvwuniversit[email protected] Hyderabad Institute of Technology and Management (HITAM), Hyderabad ARTICLE INFO ABSTRACT ©2025 RS Publication Paper ID: IJPHC69343891BD1E4 Published: 2025-12-07 DOI: https://dx.doi.or g/10.5281/zenodo. 17848453 Page No: 121-125 This study investigates the effects of an Ayurvedic diet on physio logical, biochemical, and psychological variables in middle-aged women with Type II diabetes. Forty-five patients, aged 45-60, participated from online workshops in Karnataka, India. Over 45-50 days, participants practiced yoga daily and subsequently followed an Ayurvedic diet. Measured variables included blood pressure, pulse rate, BMI, stress, self-confidence, depression, glucose tolerance test, and lipid profile. Results indicated significant reductions in blood sugar, triglycerides, and total cholesterol. The study suggests conducting similar research for younger and older adults, as well as for cardiac and hypertensive patients. Key words: Ayurveda Diet, Physiological, Biochemical, Psychological, Diabetic Type II Patients, Blood Sugar, Total Cholesterol, Lipid Profile, Glucose Tolerance Test, Polyphenols International Journal of Pharmaceutical Science and Health Care Available online on http://www.rspublication.com/ijphc/index.html ISSN 2249 – 5738 Cite This Paper: Dr C.G. Vishnu Kumar, Prof. Dr. Ashalatha and Dr S. Siva Prasad Rao (2025). "EVALUATION STUDY OF POLYPHENOLS IN AYURVEDIC DIETARY SUPPLEMENTS AND YOGA THERAPY ON MIDDLE-AGED WOMEN WITH TYPE II DIABETES". INTERNATIONAL JOURNAL PHARMACEUTICAL SCIENCE AND HEALTH CARE (IJPHC), vol. 15, no. 6, 2025, pp. 121-125. DOI: https://dx.doi.org/10.5281/zenodo.17848453 International Journal of Pharmaceutical Science and Health Care Volume 15, Number 6, 2025 Available online on http://www.rspublication.com/ijphc/index.html ISSN 2249 – 5738 DOI: 10.5281/zenodo.17848453 Original Article ©2025 RS Publication, [email protected] 122 INTRODUCTION Ayurvedic diet interventions, combined with yogic methods, address various ailments and promote optimal health, healing, and enlightenment. Classes are designed for specific conditions, including diabetes, with a therapeutic focus. Ayurveda distinguishes three gunas: rajas (motion), tamas (inertia), and sattva (balance). Sattvic foods are fresh, pure, and rich in vitamins, while tamasic foods (like fast food and junk food) are considered unhealthy. POLYPHENOLS IN AYURVEDIC DIETARY SUPPLEMENTS As Type 2 diabetes prevalence grows, Ayurvedic medicine offers alternatives using polyphenolic herbs such as cinnamon, fenugreek leaves, and amala. Diabetes is a complex metabolic disease affecting insulin and glucose regulation. Yoga supports diabetes management by focusing on balanced diets, lifestyle, endocrine health, and stress reduction. Ayurveda classifies foods by their effects on constitutions: pitta types avoid spicy foods, vatas benefit from warm, nourishing meals, and kaphas are advised to limit sweets and fats. Nutritional guidelines are rooted in ancient Indian medical systems and adapted for individual needs. PROGRAM OVERVIEW The program combined a controlled Ayurvedic diet, exercise, and lifestyle changes based on yoga therapy principles, with self-monitoring and workshops. The six-week course aimed to modify eating and activity habits, enhance self-efficacy, improve quality of life, and address stress and hormonal imbalance in diabetes and weight management. TRIDOSHA AND PRAKRITI Ayurveda identifies three doshas—Vata, Pitta, and Kapha—representing fundamental bodily humors. A person’s constitution (Prakriti) is unique and influences dietary and lifestyle recommendations. Five elements—earth, water, fire, air, and ether—manifest in both the universe and the human body. Understanding Prakriti assists practitioners in dietary assessment, behavior analysis, disease prediction, and treatment. A nutritious diet, proper meal timing, and adequate sleep are emphasized for optimal health and disease prevention. STATEMENT OF THE PROBLEM This study explores the effect of Ayurvedic diet principles on physiological, psychological, and biochemical variables in middle-aged women with Type II diabetes. OBJECTIVES  To raise awareness about the importance of Ayurvedic diet in lifestyle changes for diabetic women.  To determine significant differences in selected physiological, biological, and psychological variables due to Ayurvedic diet practices among diabetic women. International Journal of Pharmaceutical Science and Health Care Volume 15, Number 6, 2025 Available online on http://www.rspublication.com/ijphc/index.html ISSN 2249 – 5738 DOI: 10.5281/zenodo.17848453 Original Article ©2025 RS Publication, [email protected] 123 DELIMITATIONS  Confined to middle-aged women with Type II diabetes, aged 35–50 years.  Study includes 90 participants (45 experimental, 45 control) from Udupi only.  Duration: 6–8 weeks.  Subjects recruited from Neo Wellness Centre branches in Udupi.  Focus on selected Ayurvedic diet and yogic practices groups.  Limited to fasting and postprandial sugar tests and stress factors. LIMITATIONS  Day-to-day activities and counseling not controlled.  Acute cases excluded.  Diets controlled, but medical treatment not controlled. SIGNIFICANCE  Improves understanding of physiological, psychological, and biochemical changes among diabetic women following Ayurvedic diet and yoga therapy.  Provides assessment opportunities for therapists.  Motivates further research into Ayurvedic diet and yogic practices for diabetes management. METHODOLOGY Ninety participants (45 experimental, 45 control) from Udupi, aged 45–60, engaged in yoga asanas for 45–50 days and followed an Ayurvedic diet. Variables such as blood sugar, lipid profile, and total cholesterol were measured before and after the intervention by a qualified technician. Workshops addressed diabetes and hypertension. ANCOVA and Scheffe’s post-hoc test were used to assess differences at a 0.05 confidence level. Neo Wellness Centre ensured patient confidentiality and obtained necessary permissions. AYURVEDIC DIET TRAINING SCHEDULE GROUPS PROGRAMMES Experimental Group - Ayurvedic Diet Kapha - pacifying Diet Fresh Juices, Vegetables, Herbs Control Group No practice International Journal of Pharmaceutical Science and Health Care Volume 15, Number 6, 2025 Available online on http://www.rspublication.com/ijphc/index.html ISSN 2249 – 5738 DOI: 10.5281/zenodo.17848453 Original Article ©2025 RS Publication, [email protected] 124 RECOMMENDED AYURVEDIC DIET FOR 6 WEEKS S.NO RECOMMENDED FOOD ITEMS AVOIDED FOOD ITEMS 1 Bitter gourd juice, a glass of water with 10 tulsi and neem leaves, Indian gooseberry juice, special fiber diet, low glycemic and carbohydrate foods 2 Bitter gourd cooked in ghee Rice 3 Seeds of fenugreek, turmeric, white pepper powder with milk, cinnamon Cereals with high sugar content 4 Green vegetables, soy Potato RESULTS The study evaluated changes in systolic and diastolic blood pressure, pulse rate, BMI, stress, self-confidence, depression, fasting plasma glucose, oral glucose tolerance, and lipid profile before and after the intervention. Statistical analysis showed:  Significant reductions in systolic and diastolic blood pressure, pulse rate, and BMI in the Ayurvedic diet group compared to control.  Significant improvements in stress, self-confidence, and depression scores.  Significant reductions in fasting plasma glucose, 2-hour OGTT, and lipid profiles in the Ayurvedic diet group compared to control. HYPOTHESIS TESTING VARIABLE RESEARCH HYPOTHESES NULL HYPOTHESES Systolic Blood Pressure Accepted Rejected Diastolic Blood Pressure Accepted Rejected Pulse Rate Accepted Rejected BMI Accepted Rejected Stress Accepted Rejected Self Confidence Accepted Rejected Depression Accepted Rejected Fasting Plasma Glucose Accepted Rejected 2 Hr OGTT Accepted Rejected Lipid Profile Accepted Rejected SUMMARY AND CONCLUSIONS Six weeks of Ayurvedic diet practices resulted in significant improvements in physiological, psychological, and biochemical variables in middle-aged women with Type II diabetes. Compared to the control group, the intervention group showed reduced blood pressure, pulse rate, BMI, stress, depression, and improved selfconfidence. Biochemical markers such as fasting plasma glucose and lipid profile also improved significantly. International Journal of Pharmaceutical Science and Health Care Volume 15, Number 6, 2025 Available online on http://www.rspublication.com/ijphc/index.html ISSN 2249 – 5738 DOI: 10.5281/zenodo.17848453 Original Article ©2025 RS Publication, [email protected] 125 REFERENCES  A Pilot Feasibility Study of Whole-systems Ayurvedic Medicine and Yoga Therapy for Weight Loss. Jennifer Rioux, Cynthia Thomson, Amy Howerter, 2014  Abhishek Yadav (2021). Srivastava K. Concept of personality: Indian perspective of Indian Psychiatry (Jan 2021)  Ankita Thakur, Brij Kishor, Akhilesh K. Srivastava, Rajesh Manglesh. Concept and Significance of Agni in Ayurveda. 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