RESINAS COMPOSTAS COM EFEITO CAMALEÃO NA ODONTOLOGIA RESTAURADORA: REVISÃO INTEGRATIVA SOBRE MIMETISMO ÓPTICO E APLICAÇÃO CLÍNICA

304 JNT - FACIT BUSINESS AND TECHNOLOGY JOURNAL - ISSN: 2526-4281 - QUALIS B1 ANO 2025 – MÊS DE OUTUBRO - FLUXO CONTÍNUO – Ed. 67. Vol. 3. Págs. 305-317 DOI: 10.5281/zenodo.17537162 RESINAS COMPOSTAS COM EFEITO CAMALEÃO NA ODONTOLOGIA RESTAURADORA: REVISÃO INTEGRATIVA SOBRE MIMETISMO ÓPTICO E APLICAÇÃO CLÍNICA. Maria Clara Pires de Carvalho COSTA; Beatriz Limeira Cunha OLIVEIRA; Pedro Henrick de Sousa LOPES; Maria Eduarda Carvalho CAVALCANTI; Wellison Santos SÁ; Bruna de Oliveira REIS; Mila Oliveira Santos VIANA. JNT Facit Business and Technology Journal. QUALIS B1. ISSN: 2526-4281 - FLUXO CONTÍNUO. 2025 – MÊS DE OUTUBRO - Ed. 67. VOL. 03. Págs. 305-317. http://revistas.faculdadefacit.edu.br. E-mail: [email protected]. 305 RESINAS COMPOSTAS COM EFEITO CAMALEÃO NA ODONTOLOGIA RESTAURADORA: REVISÃO INTEGRATIVA SOBRE MIMETISMO ÓPTICO E APLICAÇÃO CLÍNICA CHAMELEON EFFECT COMPOSITE RESINS IN RESTORATIVE DENTISTRY: AN INTEGRATIVE REVIEW ON OPTICAL MIMICRY AND CLINICAL APPLICATION Maria Clara Pires de Carvalho COSTA Centro Universitário Afya Uninovafapi E-mail: [email protected] ORCID: http://orcid.org/0009-0001-9792-8663 Beatriz Limeira Cunha OLIVEIRA Centro Universitário Afya Uninovafapi E-mail: beatriz1.li[email protected] ORCID: http://orcid.org/0009-0007-0321-8338 Pedro Henrick de Sousa LOPES Centro Universitário Afya Uninovafapi E-mail: pedrohenri[email protected] ORCID: http://orcid.org/0009-0002-9951-7546 Maria Eduarda Carvalho CAVALCANTI Ientro Universitário Afya Uninovafapi E-mail: [email protected] ORCID: http://orcid.org/0009-0009-3627-0444 Wellison Santos SÁ Universidade Federal do Piauí (UFPI) E-mail: [email protected] ORCID: http://orcid.org/0009-0007-7253-8415 Bruna de Oliveira REIS FocusGrupo Educacional E-mail: [email protected] ORCID: http://orcid.org/0000-0002-4461-1183 Mila Oliveira Santos VIANA Universidade Federal do Piauí (UFPI) E-mail: [email protected] ORCID: http://orcid.org/0000-0001-5393-9036 RESINAS COMPOSTAS COM EFEITO CAMALEÃO NA ODONTOLOGIA RESTAURADORA: REVISÃO INTEGRATIVA SOBRE MIMETISMO ÓPTICO E APLICAÇÃO CLÍNICA. Maria Clara Pires de Carvalho COSTA; Beatriz Limeira Cunha OLIVEIRA; Pedro Henrick de Sousa LOPES; Maria Eduarda Carvalho CAVALCANTI; Wellison Santos SÁ; Bruna de Oliveira REIS; Mila Oliveira Santos VIANA. JNT Facit Business and Technology Journal. QUALIS B1. ISSN: 2526-4281 - FLUXO CONTÍNUO. 2025 – MÊS DE OUTUBRO - Ed. 67. VOL. 03. Págs. 305-317. http://revistas.faculdadefacit.edu.br. E-mail: [email protected]. 306 RESUMO Objetivo: Analisar o desempenho óptico e clínico de resinas compostas com efeito camaleão, com ênfase na sua capacidade de mimetização da cor dentária. Método: Foram incluídos 12 estudos, sendo 8 experimentais/laboratoriais (in vitro), 1 ensaio clínico randomizado e 3 relatos de caso clínico, publicados entre 2006 e 2025. A metodologia consistiu na seleção de artigos que avaliaram propriedades como translucidez, espessura, índice de refração e tipo/tamanho das partículas de carga. Resultados: As resinas com partículas supranano e elevada translucidez apresentam maior dispersão da luz, favorecendo o efeito camaleão; além disso, ensaios clínicos e relatos de caso evidenciaram boa estabilidade de cor, adaptação marginal satisfatória e simplificação do protocolo restaurador, otimizando o tempo clínico. Contudo, constatou-se significativa heterogeneidade metodológica nos estudos, variando-se os substratos, métodos de avaliação (ΔE objetiva versus análise visual) e ausência de ensaios clínicos de longo prazo, o que limita a comparabilidade dos dados. Recomenda-se que pesquisas futuras explorem materiais inteligentes com adaptação óptica dinâmica e conduzam estudos longitudinais em ambiente clínico para consolidar sua eficácia e aplicabilidade. Conclusão: Apesar de promissoras e alinhadas ao ideal biomimético, as resinas com efeito camaleão requerem validação clínica mais robusta e padronização de protocolos de avaliação. Palavras-chave: Resinas compostas. Cor. Materiais dentários. Espectrofotometria. Biomimética. ABSTRACT Objective: This study, through an integrative literature review, analyzes the optical and clinical performance of chameleon-effect composite resins, with an emphasis on their ability to mimic tooth color. Method: Twelve studies were included, comprising 8 experimental/laboratory (in vitro) investigations, 1 randomized clinical trial, and 3 clinical case reports, published between 2006 and 2025. The methodology consisted of selecting articles that evaluated properties such as translucency, thickness, RESINAS COMPOSTAS COM EFEITO CAMALEÃO NA ODONTOLOGIA RESTAURADORA: REVISÃO INTEGRATIVA SOBRE MIMETISMO ÓPTICO E APLICAÇÃO CLÍNICA. Maria Clara Pires de Carvalho COSTA; Beatriz Limeira Cunha OLIVEIRA; Pedro Henrick de Sousa LOPES; Maria Eduarda Carvalho CAVALCANTI; Wellison Santos SÁ; Bruna de Oliveira REIS; Mila Oliveira Santos VIANA. JNT Facit Business and Technology Journal. QUALIS B1. ISSN: 2526-4281 - FLUXO CONTÍNUO. 2025 – MÊS DE OUTUBRO - Ed. 67. VOL. 03. Págs. 305-317. http://revistas.faculdadefacit.edu.br. E-mail: [email protected]. 307 refractive index, and filler particle type/size. Results: Resins with supranano particles and high translucency exhibit greater light scattering, favoring the chameleon effect. Furthermore, clinical trials and case reports have demonstrated good color stability, satisfactory marginal adaptation, and simplified restorative protocols, optimizing clinical time. However, significant methodological heterogeneity was observed in the studies—with varying substrates, assessment methods (objective ΔE versus visual analysis), and a lack of long-term clinical trials— which limits data comparability. Future research is recommended to explore smart materials with dynamic optical adaptation and conduct longitudinal studies in a clinical setting to consolidate their efficacy and applicability. Conclusion: Although promising and aligned with the biomimetic ideal, chameleon effect resins require more robust clinical validation and standardization of evaluation protocols. Keywords: Composite resins. Color. Dental materials. Spectrophotometry. Biomimetics. INTRODUCTION Contemporary dentistry is characterised by continuous technological advances that directly impact various areas of clinical practice. These advancements range from diagnostic imaging methods, such as digital radiography and computed tomography, to the development of high-performance restorative materials. A significant milestone in history of restorative dentistry occurred in the 1960s with Bowen's studies at Northwestern University, which led to the creation of the first composite resin. Initially formulated with the monomer bisphenol Aglycidyl methacrylate (Bis-GMA) and the cross-linking agent PDMS–dimethacrylate (DMA), successive improvements to this technology have been made over the decades. The incorporation of new monomers, such as triethylene glycol dimethacrylate (TEGDMA), urethane dimethacrylate (UDMA) and ethylene glycol dimethacrylate (EGDMA) resulted in significant improvements in mechanical strength, dimensional stability and clinical handling of the material (Bortolon, 2024; Donato, 2022). RESINAS COMPOSTAS COM EFEITO CAMALEÃO NA ODONTOLOGIA RESTAURADORA: REVISÃO INTEGRATIVA SOBRE MIMETISMO ÓPTICO E APLICAÇÃO CLÍNICA. Maria Clara Pires de Carvalho COSTA; Beatriz Limeira Cunha OLIVEIRA; Pedro Henrick de Sousa LOPES; Maria Eduarda Carvalho CAVALCANTI; Wellison Santos SÁ; Bruna de Oliveira REIS; Mila Oliveira Santos VIANA. JNT Facit Business and Technology Journal. QUALIS B1. ISSN: 2526-4281 - FLUXO CONTÍNUO. 2025 – MÊS DE OUTUBRO - Ed. 67. VOL. 03. Págs. 305-317. http://revistas.faculdadefacit.edu.br. E-mail: [email protected]. 308 The evolution also involved inorganic filler particles, whose variation in size, morphology, and composition resulted in different generations and classifications of composite resins, with specific properties of strength, aesthetics, and polishability (Oliveira, 2024; Paravina, 2006). In recent years, driven by growing demand for more natural-looking, the dental industry has focused on the development of composite resins with advanced optical properties, including universal-color resins and chameleon-effect resins. In the Brazilian context, recent studies have also highlighted the growing adoption of single-shade composite resins as an alternative to simplify the restorative process (Bortolon, 2024), while also demonstrating esthetic benefits and reduced clinical time (Castro et al, 2024). These innovative materials can adapt chromatically to the adjacent dental structure, macthing the color of natural teeth more efficiently and thus reducing the need to select multiple shades at the time of restoration (Anwar, 2024; Guimarães, 2023). This property, known as the “chameleon effect,” is the result of a complex interaction between the translucency of the material, the refractive index of the matrix and fillers, and the thickness of the restoration (Vattanaseangsiri, 2022; Yamaguchi, 2021). In this context, it is essential to understand the optical principles underlying the clinical performance of these resins, as well as to evaluate their advantages and limitations relative to conventional composite resins. Accordingly, this literature review aims to address the following research question: What optical mechanisms are responsible for the chameleon effect in composite resins, and how do these materials perform clinically compared to conventional resins? The objective of this work is to review the scientific literature on chameleoneffect composite resins, analyzing the optical mechanisms that enable their chromatic adaptation and comparing their clinical performance, advantages, and limitations in relation to conventional composite resins. METHODS The current study is an integrative literature review with a descriptive approach, which aims to analyze scientific publications related to chameleon-effect RESINAS COMPOSTAS COM EFEITO CAMALEÃO NA ODONTOLOGIA RESTAURADORA: REVISÃO INTEGRATIVA SOBRE MIMETISMO ÓPTICO E APLICAÇÃO CLÍNICA. Maria Clara Pires de Carvalho COSTA; Beatriz Limeira Cunha OLIVEIRA; Pedro Henrick de Sousa LOPES; Maria Eduarda Carvalho CAVALCANTI; Wellison Santos SÁ; Bruna de Oliveira REIS; Mila Oliveira Santos VIANA. JNT Facit Business and Technology Journal. QUALIS B1. ISSN: 2526-4281 - FLUXO CONTÍNUO. 2025 – MÊS DE OUTUBRO - Ed. 67. VOL. 03. Págs. 305-317. http://revistas.faculdadefacit.edu.br. E-mail: [email protected]. 309 composite resins, especially with regard to their optical mechanisms and clinical performance. The search was conducted between April and June 2025 in the PubMed, Scopus, and SciELO databases, using the following descriptors combined with Boolean operators: “chameleon effect resin composite,” “single-shade composite,” “universal shade resin,” “esthetic dentistry,” and their equivalents in Portuguese. Original articles published between 2006 and 2025, written in Portuguese or English, that addressed clinical or laboratory aspects of chameleon effect composite resins were included. To ensure the practical and scientific relevance of the findings, only well-documented in vitro, in vivo, clinical trials, or clinical case reports were considered. Nineteen articles were initially selected. Literature reviews, systematic reviews, academic works (such as term papers, dissertations, and theses), duplicate articles, and publications with insufficient methodological description were excluded. After reading the titles, abstracts, and full texts, 12 articles remained that fully met the established criteria and were used in the results section. RESULTS After a rigorous literature review, 12 articles were selected. For clarity in data presentation, the studies were organized into two tables: Table 01 provides a comprehensive overview of the analyzed articles, while Table 02 classifies them according to thematic categories and main findings, facilitating a systematic and detailed understanding of the properties of chameleon-effect composite resins. Table 1: Selected Studies for Analysis. Título Autoria Periódico Use of chameleon composite resins in Dentistry: case report Freitas et al. (2024) Revista SulBrasileira de Odontologia Color match analysis of single-shade and multi-shade composite resins using spectrophotometric and visual methods after bleaching Cubukcu et al. (2023) Dental Materials RESINAS COMPOSTAS COM EFEITO CAMALEÃO NA ODONTOLOGIA RESTAURADORA: REVISÃO INTEGRATIVA SOBRE MIMETISMO ÓPTICO E APLICAÇÃO CLÍNICA. Maria Clara Pires de Carvalho COSTA; Beatriz Limeira Cunha OLIVEIRA; Pedro Henrick de Sousa LOPES; Maria Eduarda Carvalho CAVALCANTI; Wellison Santos SÁ; Bruna de Oliveira REIS; Mila Oliveira Santos VIANA. JNT Facit Business and Technology Journal. QUALIS B1. ISSN: 2526-4281 - FLUXO CONTÍNUO. 2025 – MÊS DE OUTUBRO - Ed. 67. VOL. 03. Págs. 305-317. http://revistas.faculdadefacit.edu.br. E-mail: [email protected]. 310 Source: elaborated by the authors. Table 02: Summary of key findings by topic category. Thematic category Related studies Main findings Optical properties and Chromatic adaptation Yamaguchi et al. (2021) (in vitro); Vattanaseangsiri et al. (2022) (in vitro); Fernandese-Silva et al. (2025) (in vitro); Karadağ et al. (2024) (laboratorial); Paravina et al. (2006) (experimental) Studies have demonstrated that translucency, thickness, and particle size are critical determinants of tooth-color matching. The incorporation of suprananometer-scale particles facilitates the chameleon effect through structural color mechanisms Clinical behavior and color stability Anwar et al. (2024) (ensaio clínico); Cubukcu et al. (2023) (experimental pósColor stability of monochromatic resins was found to be satisfactory in most Color matching ability of resin composites incorporating supra-nano spherical filler producing structural color Yamaguchi et al. (2021) Dental Materials Influence of restorative material translucency on the chameleon effect Vattanaseangsiri et al. (2022) Scientific Reports Optical behavior and marginal discoloration of a single shade resin composite with a chameleon effect: a randomized controlled clinical trial Anwar et al. (2024) British Dental Journal Open Color adjustment potential of two single shade resin-based composites before and after staining Karadağ et al. (2024) Cumhuriyet Dental Journal Evaluation of color stability in single‑shade composite resins using spectrophotometer and cross‑polarized mobile photography Tepe et al. (2025) BioMed Central Oral Health Influence of depth and translucency on the color matching of single-shade resin composites: An in vitro study. Fernandes-e-Silva et al. (2025) Brazilian Dental Journal Restoration in posterior tooth with monochrome resin: case report Queiroz et al. (2022) Brazilian Journal of Development Color-Matching and Blending-Effect of Universal Shade Bulk-Fill-Resin-Composite in Resin-Composite-Models and Natural Teeth. Abdelraouf & Habib (2016) BioMed Research International Color interaction of dental materials: Blending effect of layered composites. Paravina et al. (2006) Dental Materials Resinas compostas monocromáticas: Uma abordagem em caso clínico. Monochromatic composite resins: A clinical case approach. Silva et al. (2023) Research, Society and Development RESINAS COMPOSTAS COM EFEITO CAMALEÃO NA ODONTOLOGIA RESTAURADORA: REVISÃO INTEGRATIVA SOBRE MIMETISMO ÓPTICO E APLICAÇÃO CLÍNICA. Maria Clara Pires de Carvalho COSTA; Beatriz Limeira Cunha OLIVEIRA; Pedro Henrick de Sousa LOPES; Maria Eduarda Carvalho CAVALCANTI; Wellison Santos SÁ; Bruna de Oliveira REIS; Mila Oliveira Santos VIANA. JNT Facit Business and Technology Journal. QUALIS B1. ISSN: 2526-4281 - FLUXO CONTÍNUO. 2025 – MÊS DE OUTUBRO - Ed. 67. VOL. 03. Págs. 305-317. http://revistas.faculdadefacit.edu.br. E-mail: [email protected]. 311 clareamento); Tepe et al. (2025) (experimental); Abdelraouf & Habib (2016) (in vitro) studies, even following bleaching or pigmentation procedures. Marginal adaptation was considered clinically acceptable. Clinical applications (Case report) Freitas et al. (2024); Queiroz et al. (2022); Silva et al. (2023) (todos relatos de caso clínico) The cases demonstrated ease of clinical use and good aesthetic results, with shorter color selection time and favorable visual integration. Source: elaborated by the authors. DISCUSSION Optical properties and tooth color matching The tooth color matching using composite resins with a chameleon effect is the result of a set of optical properties that act synergistically. Among the most relevant factors are the translucency of the material, the refractive index of the matrix and inorganic fillers, the thickness of the application, and the size and type of filler particles. In vitro studies indicate that resins with supra-nano particles and a homogeneous matrix tend to disperse light more efficiently, favoring blending with the surrounding tooth structure (Karadağ et al, 2024; Yamaguchi et al, 2021). Brazilian academic works have also highlighted the esthetic mimicry potential of these materials, especially in anterior restorations (Oliveira, 2024). This behavior is associated with structural color mechanisms, in which the interaction of light with nanoscale particles generates visual effects similar to those found in nature, such as in butterfly wings and seashells (Paravina et al., 2006). Unlike simple pigmentation, this effect is based on the physics of light, meaning that optical adaptation is less sensitive to minor variations in the color of the underlying tooth substrate. The resin thickness applied also directly influences its ability to match the color. Thinner layers allow greater light transmission and, consequently, better visual integration with adjacent tissues (Fernandes-e-Silva et al, 2025; Paravina et al, 2006). When the thickness increases, there is greater absorption and less light transmission, which can compromise the chameleon effect if the material is not RESINAS COMPOSTAS COM EFEITO CAMALEÃO NA ODONTOLOGIA RESTAURADORA: REVISÃO INTEGRATIVA SOBRE MIMETISMO ÓPTICO E APLICAÇÃO CLÍNICA. Maria Clara Pires de Carvalho COSTA; Beatriz Limeira Cunha OLIVEIRA; Pedro Henrick de Sousa LOPES; Maria Eduarda Carvalho CAVALCANTI; Wellison Santos SÁ; Bruna de Oliveira REIS; Mila Oliveira Santos VIANA. JNT Facit Business and Technology Journal. QUALIS B1. ISSN: 2526-4281 - FLUXO CONTÍNUO. 2025 – MÊS DE OUTUBRO - Ed. 67. VOL. 03. Págs. 305-317. http://revistas.faculdadefacit.edu.br. E-mail: [email protected]. 312 properly formulated (Vattanaseangsiri et al, 2022; Yamaguchi et al, 2021). The combination of composition and restorative technique, therefore, must be carefully planned to maximize optical performance. Color Stability and Clinical performance In the clinical context, color stability is essential to ensure the long-term esthetic longevity of restorations. The studies shows that universal shade resins maintain satisfactory chromatic stability over time, even when subjected to challenges such as dental bleaching or exposure to dietary staining agents (Anwar et al, 2024; Cubukcu et al, 2023). This resistance to color changes can be attributed both to the quality of the resin matrix and to the integrity of the interfaces between the components of the materials. These findings are consistent with studies evaluating the impact of bleaching agents on the color stability and optical behavior of composite restorations (Donato, 2022; Marzullo et al, 2025). In addition to color stability, marginal adaptation is clinically relevant, as failures in this region can compromise the seal, leading to marginal leakage and recurrent caries. The reviewed studies generally reported that chameleon-effect resins exhibited clinically acceptable marginal adaptation, even in restorations subjected to accelerated aging (Tepe et al., 2025). This indicates that the esthetic performance of these materials is not achieved at the expense of technical quality. However, the optical behavior may vary depending on the product line and type of application. Bulk-fill resins, for example, may exhibit reduced mimicry performance if their translucency is excessive, as the insertion thickness in these cases is greater. Controlling these factors is essential to prevent undesirable outcomes, particularly in regions with high esthetic demand (Abdelraouf; Habib, 2016; Fernandes-e-Silva et al., 2025; Paravina et al, 2006). Clinical applications and Operative advantages The clinical case reports included in the review demonstrated positive aesthetic results in different types of restorations, especially in posterior teeth, where the speed and simplicity of the restorative procedure are valued (Freitas et al, 2024;