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Cylindrical geometry: a further step in active microwave tomography

Broquetas Ibars, Antoni,Jofre Roca, Lluís,Cardama Aznar, Ángel,Elias Fusté, Antoni,Rius Casals, Juan Manuel,Romeu Robert, Jordi

Abstract

A prototype imaging system for active microwave tomography using cylindrical geometry has been developed, making is possible to obtain images of the dielectric properties of biological targets at 2.45 GHz. The system requires no mechanical movements to illuminate the body from multiple directions (views) and measure the scattered fields. In this way a complete data set consisting in 64 views is acquired in 3 s using low-power illumination. The system is described, including images obtained with biological phantoms and actual bodies.

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836 IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES, VOL. 39, NO. 5, MAY 1991 Cylind ical Geome y: A Fu he S ep in Ac i e Mic owa e Tomog aphy An oni B oque as, Membe , IEEE, Jo di Romeu, S uden Membe , IEEE, Juan M. Rius, S uden Membe , IEEE, An onio R. Elias-Fus e, Membe , IEEE, Angel Ca dama, Membe , IEEE, and Luis Jo e, Membe , IEEE Abs ac -A p o o ype imaging sys em o ac i e mic owa e omog aphy using cylind ical geome y has been de eloped, making is possible o ob ain images o he dielec ic p ope ies o biological a ge s a 2.45 GHz. The sys em equi es no me- chanical mo emen s o illumina e he body om mul iple di ec- ions ( iews) and measu e he sca e ed ields. In his way a comple e da a se consis ing in 64 iews is acqui ed in 3 s using low-powe illumina ion. The sys em is desc ibed, including im- ages ob ained wi h biological phan oms and ac ual bodies. I. INTRODUCTION URRENT esea ch in medical imaging is de o ed C bo h o imp o ing exis ing sys ems based on X ays, nuclea magne ic esonance, ul asound, e c., and o in- es iga ing o he eme ging echniques such as applied po en ial imaging [l] and mic owa e imaging [2]. The in e es in de eloping new imaging me hods when e y good ones al eady exis lies basically in he di e en physical pa ame e s isualized, which depend s ongly on he ype o adia ion used and i s in e ac ion wi h biologi- cal ma e ials. The objec i e o ac i e mic owa e omog aphy is o econs uc he dielec ic p ope ies o a body illumina ed wi h mic owa es om a measu emen o he sca e ed ields. Biological issues p esen la ge a ia ions in hei elec ical cha ac e is ics depending on composi ion, em- pe a u e, i iga ion, e c.; he e o e hei in e nal s uc u e and physiological changes can in p inciple be imaged [3], [41. Unlike ionizing adia ion, low-powe mic owa e adia- ion allows a i ually sa e explo a ion o li ing issues; hus e en con inuous moni o ing can be en isaged. Mo e- o e he echnology in ol ed is common o ada and communica ion sys ems; hus i is well de eloped and inexpensi e. Some d awbacks o his echnique a e i s low esolu ion (o he o de o a wa eleng h o he adia ion in issue), Manusc ip ecei ed July 23, 1990; e ised Decembe 17, 1990. This wo k was suppo ed by he Spanish Commi ee o Scien i ic and Tech- nical Resea ch (CAICYT) unde G an 1165-84, by he Spanish Na- ional Ins i u e o Heal h (FISS) unde G an 84/2112, by he Spanish-F ench Coope a ion P og am unde G an 30/135, and by he Spanish-B i ish Coope a ion P og am unde G an 17/173. The au ho s a e wi h he TSC Dep ., G oup AMR, Uni e si a Poli cnica de Ca alunya, P.O. Box 30002, 08080 Ba celona, Spain. IEEE Log Numbe 9143002. he high a enua ion ha biological ma e ials p esen a mic owa es, which place s ingen equi emen s on he equipmen design, and he di icul y in de eloping imag- ing algo i hms adap ed o he high dielec ic con as o biological bodies. The i s expe imen s on ac i e mic owa e biological imaging we e ca ied ou by La sen and Jacobi in he la e 1970’s [5]. The images, which showed he in e nal ea u es o an isola ed canine kidney, we e ob ained by mechani- cally scanning he body wi h a pai o an ennas and measu ing he ansmission coe icien s be ween hem. Since hen, an impo an e o has been conduc ed o design sys ems o measu e he sca e ed ields p oduced by biological bodies and imaging algo i hms adap ed o he measu emen geome y o econs uc he pe mi i i y da a [61-[14]. Con en ional mic owa e omog aphy sys ems a e based on illumina ing he body wi h a plane wa e and measu ing he sca e ing wi h a linea a ay o p obes, in a way simila o ha p oposed by Muelle in acous ic di ac ion omog aphy [ 151. Wi h plane wa e illumina ion and he assump ion o weak sca e ing bodies, he plane wa e spec um o he sca e ed ield con ains he in o ma ion on a ci cula a c o he bidimensional Fou ie spec al domain o he dielec ic p ope ies o he body [13]. Repea ing he measu emen o di e en di ec ions o incidence o iews, he spec al domain can be illed and in e ed, ob aining an image o a cu o he body. A p ac ical p oblem wi h his me hod is he need o me- chanical o a ion o ei he he body o he an enna in o de o ob ain measu emen s in di e en iews. Al- hough linea syn he ic app oaches ha e been p oposed o a oid his p oblem [9], [16], hey a e unable o p oduce comple e u n mul i iew da a wi hou o a ion. An al e - na i e p oposed by Bolomey consis s in using a wo- dimensional a ay o measu e he sca e ed ields [SI, wi h acquisi ion imes o he o de o a second. The images ob ained show de ails o he in e nal dielec ic s uc u e o dielec ic changes in eal and phan om biological bod- ies [6]-[8]. Using an enci cling geome y o measu emen would make i possible o ob ain mul i iew da a wi hou me- chanical mo emen . This pape p esen s a i s p o o ype 0018-9480/91/0500-0836$01 .00 0 1991 IEEE BROQUETAS e al.: CYLINDRICAL GEOMETRY x37 based on a cylind ical a ay, whose elemen s can be add essed independen ly as emi e s o ecei e s. This con igu a ion allows a as explo a ion o body’s cu placed along he a ay axis, in a way simila o ha o p esen X- ay scanne s. The elec omagne ic compa ibili y (EMC) o his app oach is c i ical because he s ongly a enua ed ecei ed ields a e measu ed on he same a ay which is being used o emi a high-le el illumina ing signal. The e- o e, ca e ully designed high- equency a chi ec u es and de ec ion echniques a e necessa y. The nex sec ion o he pape shows he equency choice as a comp omise be ween esolu ion o he image and ole able a enua ion, in ou p o o ype a wo king equency o 2.45 GHz has been adop ed. Sec ion 111 desc ibes he main pa s o he p o o ype, an e icien imaging algo i hm o cylind ical geome y and he main WORKSTATION KQU1SITlOh RECONSTRUCTION I equency is inc eased. The wa eleng h in biological is- sues is subs an ially sho e han alues in ai because o he high wa e con en . Wa e has a ela i e dielec ic cons an o he o de o 70 o 80 a mic owa e equen- cies and oom empe a u es. The wa eleng h is educed in his medium by a ac o o almos 9 in ela ion o ai alues. The e o e a heo e ical esolu ion o se e al mil- lime e s can be achie ed wi h ope a ing equencies o a ew gigahe z. On he o he hand, biological bodies exhibi s ong a enua ion a mic owa e equencies because o he high con en o wa e and conduc ing solu es. The a enua ion inc eases apidly wi h equency, which limi s e ec i ely he wo king equency depending on he size o he body, he illumina ion powe , and he ecei e sensi i i y. Fo sa e y easons, he illumina ion powe densi y mus be kep below he mic owa e adia ion s anda ds o con in- uous exposu e [181. Recei e sensi i i y is linked o he in eg a ion ime o each measu emen and consequen ly is p opo ional o he acquisi ion ime. Imaging usually equi es he measu emen o housands o sca e ed ield complex da a, which means ha in o de o ha e acquisi- ion imes o he o de o seconds he in eg a ion ime mus be a ound 1 ms. F om hese conside a ions he use ul equency ange o mic owa e imaging is ound o be om below 1 GHz o la ge bodies such as he ho ax o pel is o se e al GHz o smalle ones such as limbs. In ou case a equency o 2.45 GHz has been chosen, which is assigned o indus ial-scien i ic-medical applica ions. Fig. 1. Block diag am and pho og aph o he p o o ype sys em. 111. A CYLINDRICAL PROTOTYPE SYSTEM A p o o ype cylind ical sys em has been de eloped o e alua e he pe o mance and limi a ions o his app oach and o in es iga e possible clinical applica ions. The sys- em is based on a cylind ical a ay o 64 an ennas equis- paced on a ci cle 25 cm in diame e . Al hough he a ay is in ac ci cula , he name cylind ical is used because each an enna is assumed o p oduce an almos cylind ical wa e on he illumina ed egion. In his way a bidimensional econs uc ion algo i hm has been o mula ed in cylind i- cal coo dina es. The basic measu emen o iew consis s in using an an enna o he a ay as emi e and ecei ing he sca e ed ields wi h he emaining elemen s. This p ocedu e is epea ed, sequen ially emi ing wi h each o he an ennas o comple e one u n. Thus, as many iews as a ay elemen s a e ob ained wi h no mo emen s, using a measu emen me hod e y simila o ha used in he mode n an-beam X- ay scanne s. Howe e , using ele- men s o a common a ay as emi e s and ecei e s e- qui es a complica ed add essing ne wo k wi h se e e iso- la ion speci ica ions. The main pa s o he p o o ype a e he cylind ical a ay o 64 an ennas imme sed in wa e using a plas ic cylind ical con aine ; a mic owa e dis ibu ion ne wo k ha di ec s he ansmi ed and ecei ed signals o a pai I 838 IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES, VOL. 39, NO. 5, MAY 1991 0 1 2 N1 Fig. 2. Measu emen p ocedu e in a cylind ical sys em; qe and q a e he angula coo dina es o he emi e and ecei e an ennas in ope a- ion. The objec is illumina ed sequen ially wi h he elemen s o he a ay ( iews); o each iew he sca e ed ields a e measu ed. o an ennas o he a ay; a cohe en mic owa e emi e - ecei e ; some low equency ci cui y (Fig. 1); and a 32 bi mic ocompu e ha con ols he acquisi ion and e- cons uc s and p esen s he image on a high- esolu ion colo sc een. These pa s will now be desc ibed. A. Cylind ical A ay The a ay is o med by 64 wa eguides wo king in he usual TE,, mode opened on a cylind ical E-plane expo- nen ial ape . The ape shape was op imized in o de o concen a e he ields h ough he cu o he body ex- plo ed. The elec ic ield pola iza ion is pa allel o he axis o he a ay. The diame e o he a ay is 25 cm bu owing o he ape he use ul diame e is educed o 20 cm. The a ay is ully imme sed in dis illed wa e ha ing a complex pe mi i i y o E = 77- j9 a 2.45 GHz and oom empe a u e; his medium is used o ma ch he high pe mi i i y alues o biological ma e ials. The wa e- leng h a his equency in wa e is a ound 14 mm; in his way he wa eguides dimensions a e compa able o hose used a K band in ai . Wi h he E plane designed, he ield dis ibu ion along he axis o he a ay p oduced by an emi ing elemen has a wid h o 6 cm measu ed be ween -3 dB poin s, which co esponds o he hickness o he slice o he body which is ac ually explo ed. B. Dis ibu ion Ne wo k An an enna can be used as an emi e o a ecei e , making i possible o use a unique a ay as emi e and ecei e . A comple e sca e ing measu emen would in- ol e add essing sequen ially e e y an enna o he a ay as emi e and hen measu ing he sca e ed ields on all he emaining elemen s o he a ay, as depic ed in Fig. 2. When he body o be imaged is placed in he cen e o he a ay, he ield ecei ed can be conside ed he supe posi- ion o he inciden ield which would be measu ed wi h- ou he body, plus he sca e ed ield. The sca e ed ield is p oduced by he equi alen o induced cu en s in he body and o ms he usual inpu da a o he econs uc ion algo i hms. The sca e ed ield mus be ob ained by sub- ac ing he inciden ield measu ed wi hou he body om he o al ield measu ed once he body has been placed in he measu emen egion. Because o he high a enua ion o mic owa es when p opaga ing h ough wa- e and biological ma e ials (a enua ions in excess o 100 dB a e usual), one soon ealizes he di icul y o pe o m- ing a comple e measu emen . Fi s , he sca e ed ield ecei ed by he elemen s close o he ansmi ing an- enna would be so weak compa ed wi h he inciden ield ha he o al and inciden ields will be almos equal, equi ing an imp ac ical dynamic ange o ob ain use ul da a. Ano he p oblem a ises in conside ing he isola ion o he a ay mul iplexe necessa y o a oid in e e ence be ween he high-le el ansmi ing and weak ecei ing signal pa hs. These p oblems ha e been sol ed by di iding he a ay in o se e al highly isola ed sec ions ha a e add essed globally as ansmi e o ecei e . In ou case he a ay has been di ided in o ou sec ions o 16 ele- men s each. In o de o use he same con igu a ion o ecei ing elemen s pe iew, independen ly o which posi- ion akes he emi e elemen in each sec ion, only he hal a ay opposed o he emi e is used as he ecei e . Nume ical simula ions ha e shown ha usually he sca - e ed ield is mainly di ec ed in ansmission; mo eo e he e lec ed sca e ed ields a e e y di icul o measu e by sub ac ion be ween he s ong o al and inciden ields. The 1 o 16 mul iplexe o each sec ion consis s o a bina y ee o SPDT diode swi ches. The connec ion be ween he a ay sec ion po s and he ansmi e and ecei e is made by means o a swi ching ma ix, howe e , he leakage be ween ansmi ing and ecei ing sec ions equi es nonp ac ical isola ions o he swi ches in ol ed. Thus, addi ional ways o inc easing he isola ion mus be adop ed. In his case he p oblem has been sol ed using low- equency modula ion o dis inguish he use ul signals om in e e ence. A double low- equency ampli ude modula ion is used nea he ansmi e and ecei e an ennas. The de ec ion o he ecei ed signal is syn- ch onous wi h a clock unning a he sum equency o he ansmi e and ecei e modula o s; in his way only he signals modula ed in ansmission and ecep ion a e co - ela ed wi h he de ec o clock and gi e a nonze o ou pu . This p ocedu e a oids, o example, di ec in e e ence be ween he emi e and ecei e . A low-noise ampli ie has been included in he ecei ing pa h in o de o ob ain a noise igu e a he ecei e o 3 dB. C. Mic owa e Emi e - Recei e The emi e consis s o an oscilla o phase-locked o a subha monic s able e e ence, ollowed by a powe ampli- ie deli e ing 1 W o CW signal a 2.45 GHz. The I BROUUETAS e 01.: CYLINDRICAL GEOMETRY 839 maximum inciden powe densi y in he measu emen egion o he a ay is less han 0.1 mW/cm2, which is well below he ecommended ANSI s anda d [18] limi o con inuous exposu e (5 mW/cm* a 2.45 GHz). The e- cei e uses a cohe en homodyne I/Q de ec o . A di ec- ional couple inse ed in he ansmi e pa h p o ides he LO e e ence signal o he de ec o . The in-phase and quad a u e ou pu s con ain a dc componen , as a consequence o de ec o bias and con inuous wa e in e - e ence, and low- equency modula ed signals. The de- si ed signals a e ex ac ed wi h a pai o synch onous de ec o s, p o iding a high sensi i i y o he sys em. The dc ou pu s o he de ec o s a e sampled by wo 13 bi A/D con e e s wi h an in eg a ion ime o app oxi- ma ely 1 ms. This means ha he basic dynamic ange o he sys em is 78 dB; howe e his igu e can be inc eased by da a a e aging i necessa y. D. Acquisi ion and Calib a ion The sys em is con olled by a 32 bi wo ks a ion (HP9000-320) using a pa allel inpu /ou pu bus and con en ional logic ci cui y. The acquisi ion consis s in add essing all possible pai s o sec o s, one ac ing as ansmi e and he o he as ecei e . Fo each pai he indi idual elemen s a e add essed in such a way ha o each emi ing elemen he o al ield is measu ed wi h he opposi e hal a ay. A ield da a se is a ma ix o 64x64 elemen s whe e he columns a e he ansmi ing ele- men s and he ows he ecei e s; only 2112 poin s con- ain sca e ing da a because he e lec ed ields a e no measu ed. The acquisi ion ime o he sys em is 3 s; da a a e aging makes i possible o inc ease he sys em sensi- i i y a he expense o longe measu emen imes. As poin ed ou be o e, he sca e ed ields a e ob ained by sub ac ion be ween o al and inciden ields, so s abil- i y and epea ibili y a e c ucial in he ope a ion o he sys em. Ano he impo an aspec when conside ing mea- su emen sys ems is p o iding an adequa e means o calib a ion, which has been a key ac o in mic owa e ins umen a ion. To calib a e he sys em, an objec wi h p edic able sca e ing cha ac e is ics is measu ed and hen he necessa y co ec ion coe icien s o each emi e - ecei e couple o elemen s a e ob ained by di iding he heo e ical measu emen by he ac ual one. A 4-cm-diam- e e me allic cylinde is used o his pu pose; he diame- e has been chosen as a comp omise be ween sca e ing ampli ude and ela i e la ness along he ecei ing ele- men s. IV. IMAGING ALGORITHM Unlike X ays, mic owa e adia ion has a wa eleng h compa able o he size o he objec ; hus e ac ion and di ac ion canno be neglec ed and di ac ion imaging algo i hms mus be used. In a cylind ical a ay he ield p oduced by each elemen will be app oxima ely a cylin- d ical wa e eme ging om he an enna i he ield ene gy is assumed o be con ined o he hickness o he a ay. Fo each emi e he'sca e ed ield will be measu ed on o he elemen s o he a ay, yielding a ma ix E,(cp,,cp,), whe e cp, is he angula posi ion o he ecei e elemen and cp, he angula posi ion o he emi e , as shown in Fig. 2. Using an elec ic ield pola ized axially and neglec ing depola iza ion e ec s in he body, we can use an app oxi- ma e scala ep esen a ion o cu en s and elec ic ield [ 161. Con en ional algo i hms a e based on linea geome- ies o measu emen and make use o i s -o de app oxi- ma ions, which means ha he body is assumed o pe u - ba e sligh ly he inciden ield. Illumina ing he body wi h a plane wa e, he plane wa e angula spec um o he sca e ed ield con ains he spec um o he dielec ic con as o he objec along ci cles o adius k, ( he wa enumbe o he ield in he embedding e e ence medium) [16]. The dielec ic con as C(7) is he ela i e di e ence be ween he complex pe mi i i y o each poin o he body 47) and he e e ence pe mi i i y E, co e- sponding o he embedding medium: C(J) = 1 - E(~)/E,. In ou case he geome y o measu emen is cylind ical and a simila algo i hm can be ob ained based on Hankel ans o ms; howe e his algo i hm is di icul o imple- men on a digi al compu e and e y ine icien because o he la ge numbe o Bessel unc ions in ol ed. A much mo e e icien algo i hm can be ob ained by using a syn he ic app oach o o m plane wa es as a combina ion o cylind ical wa es. Fi s , gi en he linea i y o he sca e ing, we can syn- hesize a plane wa e illumina ion in an a bi a y di ec ion by combining he measu emen s o he di e en emi e s weigh ed by he cu en dis ibu ion on he a ay ha would p oduce his plane wa e illumina ion: J 0 whe e J,(cp,; e^,> a e he cu en s on he a ay pcoducing a plane wa e in he di ec ion o he uni ec o 0,. On he o he hand, using he ecip oci y heo em, he Fou ie spec um o he induced cu en s J(7) in he dielec ic can be ob ained by weigh ing he measu emen s on he a ay a again by he cu en dis ibu ion ha would p ocuce a plane wa e in he di ec ion o he uni ec o - 0 in he egion s occupied by he body [19]: whe e R is he adius o he a ay. Assuming he sca e - ing o be su icien ly low o app oxima e he o al ield wi hin he body by he inciden ield (Bo n app oxima- ion), we can exp ess he induced cu en s in he dielec- ic as a p oduc o he dielec ic con as and he inci- den ield E,. In a lossless e e epce medium ( eal k,), his p oduc implies a shi o k,,0, be ween he spec al I I 840 IEEE TRANSAnIONS ON MICROWAVE THEORY AND TECHNIQUES, VOL. 39, NO. 5, MAY 1991 -180’ 180’ Fig. 3. Phase o a syn he ically gene a ed plane wa e om cylind ical wa es eme ging om he elemen s o he a ay. domains o cu en and con as : is he bidimensional Fou ie ans o m o he dielec ic con as C(3. Combining (0, (2), and (3), we ob ain inally he spec al domain o C(<) o? ci cula a cs o adius k, wi h coo dina es = k,(8 - 8”): *J,((Po,; e^,)R2 dcp, &e. (5) A simila exp ession was de i ed p e iously by De aney and Beylkin o a bi a y geome ies using a di e en app oach [20]. Equa ion (5) is o mally a double con olu- ion o he measu ed sca e ed ields E, wi h he cu en s on he a ay J, ha would p oduce a plane wa e illumi- na ion. The con olu ion can be e icien ly calcula ed us- ing FFT echniques as a double p oduc in he spec al domain be ween he Fou ie se ies o E, and J as de- sc ibed in [19]. Fig. 3 shows he supe posi ion o cylind i- cal wa es weigh ed by he coe icien s J,(cp). Only he phase o he esul ing plane wa e in he measu emen egion is shown o simplici y. Because o wa e a enua- ion, he ampli ude decays exponen ially. The image is ob aine: by jn e se bidimensional Fou ie ans o m once C[k,(8-8,)] has been mapped on a ec angula g id by bilinea in e pola ion in a way simila TABLE I S s em Pa ame e s F equency Powe densi y Use ul diame e Da a acquisi ion ime Recons uc ion ime Image - SDa ial esolu ion Con as esolu ion Tempe a u e esolu ion (in wa e ) 2.45 GHz < 0.1 mW/cm 20 cm 3s 31 s on HP320 8 mm 1% 0.YC o ha in linea algo i hms [16]. The econs uc ion ime is 30 s on a HP9000-320 wo ks a ion. Un o una ely he high dielec ic con as o biological bodies o en causes he b eakdown o he Bo n app oxi- ma ion [91, [16]. This depends on bo h he size and he con as o he objec . I has been ound bo h nume ically and expe imen ally ha some biological bodies wi h sec- ions o a ew wa eleng hs can be econs uc ed, e ealing quali a i ely hei in e nal s uc u e. When he size is la ge , i is s ill possible o ge use ul di e en ial econ- s uc ions showing dielec ic changes, as desc ibed in he nex sec ion. Al hough as shown in (2) he spec um o he induced cu en s can be ob ained om he sca e ed ields wi hou app oxima ions, i mus be poin ed ou ha he cu en s a e di e en o each inciden ield and a knowledge o only an a c o a wo-dimensional spec um is no enough o p oduce a ep esen a i e image o he cu en s. Fo his eason i is necessa y o map app oxi- ma ely he cu en s in o he body con as , illing i s 2-D spec um, which is in a ian wi h he inciden ield. Ano he sou ce o e o a ises because o he losses o he e e ence ma e ial (wa e ). The algo i hm desc ibed accoun s o he losses excep in he las s ep, when he image is ob ained by Fou ie in e sion o i s spec al domain using FFT unde he assump ion o a uni o m inciden ield E,. Wi h a lossy medium, E, is a enua ed; consequen ly we ha e access o he Laplace spec um o he dielec ic con as [21]. I has been s a ed by simula- ions ha his low-loss app oxima ion does no cause s ong e o s i he losses in he body a e no signi ican ly di e en om hose in he e e ence medium. Table I summa izes he main cha ac e is ics o he sys em de el- oped and he imaging algo i hm. V. RESULTS One o he ad an ages o he calib a ion me hod p e- sen ed is he possibili y o ob aining an absolu e calib a- ion o he sys em and hus being able o econs uc quan i a i ely he ac ual pe mi i i y dis ibu ion o bod- ies. To es his possibili y, a low-con as gel cylinde was measu ed and econs uc ed. Fig. 4 shows he image o complex pe mi i i y in eal/imagina y pa in a linea g ay scale. Compa ing he image alues wi h he ac ual gel pe mi i i y eg = 68- j16, he imagina y pa is well econs uc ed and he eal pa is co ec ly econs uc ed in he ex e nal laye o he cylinde . Wi h he p esen BROQUETAS e al.: CYLINDRICAL GEOMETRY 84 1 70 78 71 72 73 73 74 75 76 76 77 78 79 79 80 -19 -17 -15 -13 -12 -9.0 % -6.2 REAL I MAG Fig. 4. Quan i a i e image o complex pe mi i i y in eal/imagina y pa o a homogeneous gel od wi h pe mi i i y cs = 68- j16. algo i hm, his is possible only wi h weak sca e ing ob- jec s. The expe imen al esolu ion o he sys em has been ob ained by econs uc ing wo close hin me allic ods. The objec s ha e been ound sepa able a a minimum dis ance o 8 mm. This alue is close o he heo e ical hal -wa eleng h di ac ion limi (7 mm). Wi h high-con as biological bodies mul iple sca e ing appea s and he inciden ield is a wo se app oxima ion o he o al ield in he body; howe e he algo i hm desc ibed s ill co ec ly econs uc s small sec ion bodies. Fig. 5 shows a omog aphic image o dielec ic con as ampli ude co esponding o he inge s o a human hand. Fig. 6 is he diag am o a simpli ied a m phan om and i s econs uc ion (imagina y pa o pe mi i i y). Al hough he image is quali a i e, which means ha he econ- s uc ed dielec ic alues a e no co ec , he s uc u e o he objec is success ully isualized. Fig. 7 is he econ- s uc ion o a human o ea m in cico. The imagina y pa o he pe mi i i y shows he ou e skin and a laye s, he bones adius and ulna, and some less well de ined de ails in he muscula egion wi h a much highe dielec ic cons an . This esul shows ha i is possible o isualize high-con as bodies which all ou side he egion o alid- i y o he Bo n app oxima ion. The acquisi ion speed o he sys em makes i possible o moni o unc ional changes in a body. Fo his pu pose di e en ial images a e o med by p ocessing he di e - ence in o al ields p oduced by a e e ence and al e ed bodies. Fig. 8 shows a di e en ial image o dielec ic con as ampli ude co esponding o a blood con en al- e a ion in a human a m when a ou nique is applied [22]. This expe imen shows he po en ial applica ion Fig. 5. Tomog aphic image o he inge s o a human hand. o mic owa e imaging echniques o he moni o ing o changes in ol ing pe mi i i y al e a ions such as i - iga ion. Wa e pe mi i i y exhibi s a high sensi i i y o empe a u e (-0.5%/"C in eal pa and -2%/"C in imagina y pa ), making i possible o o m images o empe a u e changes in bodies. The empe a u e esolu- ion was ound expe imen ally o ming di e en ial images o a hin, 3-cm-diame e plas ic ube illed wi h empe a- u e con olled wa e [22]. The minimum de ec able change was 0.5"C, which co esponds o a con as esolu- ion o app oxima ely 1%. This sensi i i y is expec ed o I 842 IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES, VOL. 3Y, NO. 5, MAY 1991 Fig. 6. Diag am o a simpli ied a m phan om and i s econs uc ion. Fig. 8. Di e en ial image co esponding o a blood con en al e a ion in he a m shown in Fig. 7 when a ou nique is applied. Fig. 7. Recons uc ion o a human o ea m in .ic,o. de e io a e in biological media because o hei highe con as and losses. Mo eo e he ac ual he mal sensi i - i y o pe mi i i y is expec ed o depend on he cons i u- i e ma e ials o he issue and possible he mo egula o y mechanisms wi h impac on pe mi i i y, such as blood low a ia ions. Fu he esea ch is needed o e alua e he ac ual he mal sensi i i ies in his applica ion. Di e en ial echniques can be applied o la ge bodies when absolu e images do no show hei in e nal ea u es owing o he b eakdown o i s -o de app oxima ions [23]. Fig. 9 shows he di e en ial econs uc ion o a human head phan om when a whi e ma e equi alen medium wi h pe mi i i y E = 49 - j18.5 (close o da a epo ed in [3]) is eplaced wi h wa e wi h a highe pe mi i i y. The image o he eal pa o he dielec ic con as shows well he change, al hough he absolu e image shows only he con ou o he phan om because o i s size and high con as . A highe sensi i i y would be necessa y o isualize small pe mi i i y changes ha could be ela ed o ce eb al ac i i y. VI. CONCLUSIONS A cylind ical sys em o ac i e mic owa e omog aphy has been cons uc ed and e alua ed. The sys em allows a 64 iew scan in 3 s using mic owa e mul iplexe s. The hickness o he explo ed cu o he objec is 6 cm wide; his alue could be possibly educed using a lens o ocus he ene gy in he a ay plane. The elec omagne ic com- pa ibili y o he sys em is c i ical, and he desi ed signal has been isola ed om he in e e ence by subdi iding he a ay and using a double low- equency synch onous de ec ion. BROQUETAS e al.: CYLINDRICAL GEOMETRY 843 Fig. 9. Di e en ial econs uc ion o a human head phan om when a whi e ma e equi alen medium is subs i u ed by wa e wi h highe pe mi i i y. The imaging algo i hm is based on he syn hesis o plane wa es and can be e icien ly implemen ed on a compu e . The algo i hm is based on a bidimensional scala o mula ion o he ields, weak sca e ing, and low-loss app oxima ions. An absolu e calib a ion p oce- du e has been de eloped which allows quan i a i e imag- ing o weak sca e ing bodies. High con as bodies can be quali a i ely imaged p o iding hei size is below i e o six wa eleng hs. New algo i hms mo e adap ed o he high dielec ic con as o biological bodies would make i possible o o e come his limi a ion. Di e en ial imaging is able o econs uc dielec ic changes in he body, e en i elec ically la ge, by p ocessing he a ia ions measu ed in he o al o sca e ed ields. Some expe imen al esul s wi h phan oms and bodies in uii’o ha e shown he capabil- i y o mic owa e omog aphy o image he dielec ic s uc- u e o unc ional changes o biological bodies. Compa ed wi h o he con en ional imaging me hods, mic owa e omog aphy has se e al ad an ages. Fi s , he adia ion is nonionizing and can be conside ed i ually sa e using low-powe illumina ion. P esen acquisi ion imes o he o de o a ew seconds could be educed in he u u e, making i possible o pe o m dynamic s udies o issue mo emen s as in he hea , join s, blood essels, e c., o o isualize dielec ic changes caused by physiolog- ical and biochemical al e a ions. Finally, he high cos and en i onmen al cons ain s imposed by magne ic eso- nance imaging, X- ay CT, and posi on emission omog a- phy sys ems limi hei clinical a ailabili y. Mic owa e sys ems ha e a lowe cos and can be compa ible wi h o he clinical equipmen . These ad an ages a e expec ed o play an impo an ole in he u u e de elopmen and clinical accep ance o his echnique. Al hough he sys em has been concei ed o biomedical applica ions a 2.45 GHz, i could be easily adap ed o indus ial o nondes uc i e- es ing (NDT) pu poses scal- ing he dimensions and equency, depending on he sizes and dielec ic cha ac e is ics o he objec s. ACKNOWLEDGMENT The au ho s a e g ea ly indeb ed o E. de 10s Reyes, M. Fe ando, M. Baque o, M. Hawley, and H. Almi all o hei con ibu ions and help ul discussions. Special hanks go o A. Cano, J. Gine , and J. M. Ha o o hei suppo in he cons uc i e aspec s o he p o o ype. REFERENCES [l] D. C. Ba be , B. H. B own. and I. L. F ees on, “Imaging spa ial dis ibu ions o esis i i y using applied po en ial omog aphy,” Elec on. Le ., ol. 19, no. 22, pp, 933-934. 1983. [2] L. E. La sen e al., Eds., Medical Applica ions o Mic owa ,e Imag- ing. New Yo k: IEEE P ess, 1986, pp. 148-166. [31 M. A. S uchly and S. S. S uchly. “Dielec ic p ope ies o biological subs ances-Tabula ed,” J. Mic owa ,e Powe , ol. 15, no. 1, pp. 19-25, 1980. [4] H. P. Schwan. “Elec ical p ope ies o issue and cell suspensions,” Ad[.. Biol. and Med. Phps., ol. 5, pp. 147-209, 1957. [51 L. E. La sen and J. H. Jacobi, “Mic owa e sca e ing pa ame e image y o an isola ed canine kidney,” Med. Phys., ol. 6. no. 5, pp. 394-403, Sep ./Oc . 1979. [6] G. Pe onne . Ch. Picho , J. Ch. Bolomey, and L. 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Kak, "Imaging wi h di ac ion omog aphy." Pu due Uni e si y, School o Elec . Eng., Tech. Rep. TR-EE 85-5. 1985. J. W. Goodman, I i duc ion o Fou ie Op ics. New Yo k: Mc- G aw-Hill. 1968. Ame ican Na ional S anda ds Ins i u e ANSI C95.1- 1982 "Sa e y le els wi h espec o human exposu e o adio equency elec o- magne ic ields, 300 kHz o 100 GHz." IEEE. New Yo k, NY. 1001 7. J. M. Rius. M. Fe ando. L. Jo e. and A. B oque as. "Mic owa e omog aphy: An algo i hm o cylind ical geome ies." Elec on. Le .. ol. 23, no. 11. pp. 564-565. 1987. A. J. De aney and G. Beylkin. "Di ac ion omog aphy using a bi a y emi e and ecei e su aces." Lil uson. Imaging. no. 6. pp. 181-193. 1984. M. Azimi and A. C. Kak. "Mul iple sca e ing and a enua ion phenomena in di ac ion imaging," Pu due Uni .. School o Elec . Eng., Tech. Rep. TR-EE 85-4. 1985. L. Jo e e U/., "Medical imaging wi h a mic owa e omog aphic scanne ," IEEE T am. Bio ned. Eng,. ol. BME-37. pp. 303-312. Ma . 1990. A. B oque as e U/., "Tempe a u e and pe mi i i y measu emen s using a cylind ical mic owa e imaging sys em." in ' oc. 17 h Eu o- pea ? Mic wu .e C 7 ., (Rome). 1987, pp. 892-895. ol ed in p opaga ioi U.P.C.. whe e he is ada . n An oni B oque as (S'81-M'90) was bo n in Ba celona. Spain. in 1959. He ecei ed he Inge- nie o deg ee in elecommunica ion enginee ing om he Uni e si a Poli 6cnica de Ca alunya (U.P.C.) in 1985. and he Doc o Ingenie o de- g ee in 1989 in elecommunica ion enginee ing o his wo k in mic owa e omog aphy. In 1984 he joined he Elec ophysics g oup o he U.P.C. wo king in mic owa e sys ems and digi al adio links. In 1986 he was a esea ch assis an a Po smou h Poly echnic (U.K.) in- s udies. Cu en ly he is Associa e P o esso a :ngaged in esea ch on mic owa e imaging and Jo di Romeu (S'XX) was bo n in Ba celona, Spain. in 1962. He ecei ed he Ingenie o de- g ee in elecommunica ion enginee ing in 1986 om he Uni e si a Poli kcnica de Ca alunya. In 1985 he joined he An enna-Mic owa e- Rada g oup o he Signal Theo y and Commu- nica ions Depa men he e. His esea ch deals wi h mic owa e imaging, an enna nea ield measu emen s. and an enna diagnos ic a eas. Juan M. Rius (S'89) wds bo n in Ba celona. Spain. in 1963 IIe ecei ed he Ingenie o de- g ee in elecommunicd ion enginee ing om he Uni e sidad Poli 6cnica de Ca alunya (U P C ) in 1987 In 1985 he joined he Elec ophysics g oup a U P C wo king on cylind ical geome y algo- i hms o mic owd e omog aphy. Cu en ly he 15 Associa e P o esw d he Telecommunica- ion Enginee ing School o UP C. and is in- ol ed in elec omagne ic xa e ing echniques o ddd c oss sec ion nume icdl p edic ion An onio R. Elias-Fus e (S'81-M'82) wa5 bo n in Ce e a. Spain, in 1954. He ecei ed he Inge- nie o and Doc o Ingenie o deg ees in elecom- munica ion enginee ing, bo h om he Uni e si- a Poli &cnica de Ca alunya (U.P.C.), in 1978 and 1982. espec i ely. In 1976 he joined he An enas-Mic oondas- Rada G oup o he Depa men o Signal The- o y and Communica ions o he Escuela Ticnica Supe io de Ingenie os de Telecomunicaci6n de Ba celona. whe e his wo k deal wi h mic owa e cha ac e iza ion and RF sys ems design. He became Associa e P o esso in 1985 and P o esso in 1990 a U.P.C., engaged in esea ch in he ield o ada . He is au ho and coau ho o se e al epo s o indus y and o pape s published in echnical jou nals and con e ence p oceedings. D . Elias-Fu C is an AOC membe . Cu en ly, he is Chai man o he AES Spanish Chap e . Angel Ca dama (S'67-M'73) was bo n in San i- ago. Spain, on May 13, 1944. He ecei ed he lngenie o de Telecomunicaci6n deg ee om he Uni e sidad Poli Ccnica de Mad id, Mad id, Spain. in 1968. and he Sc.M. and Ph.D. deg ees in elec ical enginee ing om B own Uni e si y, P o idence, RI, in 1970 and 1973, espec i ely. In 1972 he joined he acul y o he E.T.S.I. de Telecomunicacibn a he Poly echnic Uni e - si y o Ca alonia. Ba celona, Spain, whe e he holds he posi ion o P o esso . His esea ch in e es s ange om p opaga ion in op ical ibe s, high equency ape - u e and a ay an ennas, and nea - ield an enna scanning sys ems o he design o mic owa e imaging sys ems and ada an ennas. Luis Jo e (S'79-M'83) was bo n in Ma a 6. Spain. in 1956. He ecei ed he Ingenie o and Doc o lngenie o deg ees in elecommunica ion enginee ing, bo h om he Uni e si a Poli knica de Ca alunya (U.P.C.) in 1978 and 1982. espec i ely. In 1978 he was a Resea ch Assis an in he Elec ophysics g oup a U.P.C., whe e he wo ked on he analysis and nea - ield measu emen o an ennas. In 1981 he joined he Ecole Sup ieu e d'Elec ici 6 in Pa is, whe e he was in ol ed in mic owa e imaging echniques o biomedical applica ions. Du ing he pe iod 1986-1987 he was a Visi ing Fulb igh Schola a he Geo gia Ins i u e o Technology, A lan a, wo king on an enna measu e- men and elec omagne ic imaging. He is cu en ly P o esso and Di ec- o o he Telecommunica ion Enginee ing School a U.P.C., whe e he is engaged in esea ch on an ennas and elec omagne ic sca e ing and imaging, bo h nume ical and expe imen al aspec s.