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A Psl-like polysaccharide has a key role in the biofilm architecture of two plant-associated Pseudomonas

Heredia Ponce, Zaira María,Purtschert, G.,Gutiérrez Barranquero, José Antonio,Eberl, Leo,De-Vicente-Moreno, Antonio,Cazorla-López, Francisco Manuel

Abstract

The Psl polysaccharide has only been studied in Pseudomonas aeruginosa, and its role in bacteria that interact with plants is still unknown. On the one hand, P. syringae is a model of study of plant-pathogen interactions. On the other hand, P. chlororaphis is a biocontrol agent of plant-fungal diseases, as the white root rot caused by Rosellinia necatrix. In silico analysis have let us identify in both species a genomic region which is ortholog to the Psl-encoding region of P. aeruginosa PAO1. We constructed mutants of this region in both strains and analysed its phenotype in biofilm formation, both in static microwell plates and dynamic flow-cell chamber experiments. The results revealed a different and an important role of this polysaccharide in the biofilm architecture of both strains. Furthermore, in P. syringae this Psl-like polysaccharide has a very important role in swarming motility. All these striking phenotypes led us further study the implication of this polysaccharide in the lifestyles of both models of plant-bacteria interaction.

Full text

A Psl-like polysaccha ide has a key ole in he bio ilm a chi ec u e o wo plan - associa ed Pseudomonas He edia-Ponce, ZM; Pu sche , G; Gu ié ez-Ba anque o, JA; G; Ebe l, L.; de Vicen e, A; Cazo la, FM The Psl polysaccha ide has only been s udied in Pseudomonas ae uginosa, and i s ole in bac e ia ha in e ac wi h plan s is s ill unknown. On he one hand, P. sy ingae is a model o s udy o plan -pa hogen in e ac ions. On he o he hand, P. chlo o aphis is a biocon ol agen o plan - ungal diseases, as he whi e oo o caused by Rosellinia neca ix. In silico analysis ha e le us iden i y in bo h species a genomic egion which is o holog o he Psl-encoding egion o P. ae uginosa PAO1. We cons uc ed mu an s o his egion in bo h s ains and analysed i s pheno ype in bio ilm o ma ion, bo h in s a ic mic owell pla es and dynamic low-cell chambe expe imen s. The esul s e ealed a di e en and an impo an ole o his polysaccha ide in he bio ilm a chi ec u e o bo h s ains. Fu he mo e, in P. sy ingae his Psl-like polysaccha ide has a e y impo an ole in swa ming mo ili y. All hese s iking pheno ypes led us u he s udy he implica ion o his polysaccha ide in he li es yles o bo h models o plan -bac e ia in e ac ion.