Desarrollo de un test de aliento para el estudio del proceso de acomodación gástrica

Rafael Tojo González Tesis Doctoral DESARROLLO DE UN TEST DE ALIENTO PARA EL ESTUDIO DEL PROCESO DE ACOMODACIÓN GÁSTRICA Departamento de Medicina Facultad de Medicina y Odontología Santiago de Compostela, 2009 Dr. Dn. J. Enrique Domínguez Muñoz, Profesor Asociado del Departamento de Medicina, Facultad de Medicina y Odontología, Universidad de Santiago de Compostela, certifica que: Dn. Rafael Tojo González, Licenciado en Medicina y Cirugía por la Universidad de Santiago de Compostela, ha realizado bajo mi dirección y supervisión la presente tesis doctoral, titulada “Desarrollo de un test de aliento para el estudio del proceso de acomodación gástrica”, que reune todas las condiciones para optar al grado de Doctor en Medicina, y autoriza su presentación para que sea juzgada por el tribunal correspondiente. Para que así conste, firmo la presente en Santiago de Compostela, a ocho de junio de dos mil nueve. Fdo. Dr. Dn. J. Enrique Domínguez Muñoz Agradecimientos: Al Dr. Enrique Domínguez Muñoz, de la Universidad de Santiago. Al personal de la Fundación para la Investigación en Enfermedades del Aparato Digestivo. A los estudiantes que han participado en el estudio. Al Dr. Eduardo Fonseca, de la Universidad de Oviedo. Al Dr. Lukas Van Oudenhove, de la Katholieke Universiteit, Lovaina. A la Dra. Monika Kwiatek, de la Northwestern University, Chicago. Al Prof. Rafael Tojo Sierra, de la Universidad de Santiago. A mi familia "#$%&'! 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''>W[T$%X'4O4Q!8Xp\Wd!45M!W\`W!4N!"XcbY!&0*?W@!n!kX]V_d]\`!a\!YpX`W\N! ! ! ! ''>W[T$%X'4O4Q!8Xp\Wd!45M!W\`W!9N!"XcbY!&0*?W@!n!kX]V_d]\`!a\!YpX`W\N' ! ! ?! 3%3;%*>)10"1TYPE THE DOCUMENT TITLE! ! 246 Nombre: Sujeto 6 Número: 6 Peso (Kg.): 68 Talla (m.): 1.70 Sexo: Masculino IMC (Kg/m2): 23.5 BSA (m2): 1.7974 Edad (años): 25 Parámetros Volumen (ml.) Modelo Error t ! (min.) t lag (min.) GEC (min.) 200 2 2.9333 44.22 13.80 4.02 400 2 5.9527 42.57 -27.66 4.09 600 2 1.6096 39.98 -25.68 4.00 800 2 2.1937 37.06 -25.43 3.88 Parámetros Comida 1 Parámetros Comida 1 Cálculo Modelo 1-PDR 1 Cálculo Modelo 2-PDR 1 Variables t (1/2) = 42.50 t (1/2) = 44.22 t (1/2) = 44.22 t lag = 14.73 t lag = 13.80 t lag = 13.80 GEC = 4.02 GEC = GEC = 4.02 Error = 3.9645 Error = 2.9333 Error = 2.9333 Parámetros Comida 2 Parámetros Comida 2 Cálculo Modelo 1-PDR 2 Cálculo Modelo 2-PDR 2 Variables t (1/2) = 41.01 t (1/2) = 42.57 t (1/2) = 42.57 t lag = 13.26 t lag = -27.66 t lag = -27.66 GEC = 4.09 GEC = GEC = 4.09 Error = 7.4624 Error = 5.9527 Error = 5.9527 Parámetros Comida 3 Parámetros Comida 3 Cálculo Modelo 1-PDR 3 Cálculo Modelo 2-PDR 3 Variables t (1/2) = 38.49 t (1/2) = 39.98 t (1/2) = 39.98 t lag = 4.91 t lag = -25.68 t lag = -25.68 GEC = 4.00 GEC = GEC = 4.00 Error = 1.9178 Error = 1.6096 Error = 1.6096 Parámetros Comida 4 Parámetros Comida 4 Cálculo Modelo 1-PDR 4 Cálculo Modelo 2-PDR 4 Variables t (1/2) = 35.69 t (1/2) = 37.06 t (1/2) = 37.06 t lag = 6.04 t lag = -25.43 t lag = -25.43 GEC = 3.88 GEC = GEC = 3.88 Error = 2.6409 Error = 2.1937 Error = 2.1937 Cuestionario de síntomas Plenitud Postprandial Distensión en Abdomen Superior Saciedad Precoz Dolor/Molestias en Abdomen Superior Nauseas Comida 1 0 0 1 0 0 Comida 2 0 0 1 0 0 Comida 3 0 0 1 0 0 Comida 4 0 0 1 0 0 ' -XYZX'JHQ!0YWd`!a\Z!`Xp\Wd!(N! ! ! ! ! ! !TYPE THE DOCUMENT TITLE1#'@*/! A! ! 247 Nombre: Sujeto 7 Número: 7 Peso (Kg.): 70 Talla (m.): 1.70 Sexo: Femenino IMC (Kg/m2): 24.2 BSA (m2): 1.8257 Edad (años): 22 Parámetros Volumen (ml.) Modelo Error t ! (min.) t lag (min.) GEC (min.) 200 1 0.9447 79.58 56.78 3.55 400 2 3.6093 79.05 -36.31 3.64 600 2 5.8155 87.81 -36.87 3.69 800 2 2.4395 68.81 -33.73 3.80 Parámetros Comida 1 Parámetros Comida 1 Cálculo Modelo 1-PDR 1 Cálculo Modelo 2-PDR 1 Variables t (1/2) = 79.58 t (1/2) = 85.29 t (1/2) = 79.58 t lag = 56.78 t lag = 55.69 t lag = 56.78 GEC = 3.55 GEC = GEC = 3.55 Error = 0.9447 Error = 1.1095 Error = 0.9447 Parámetros Comida 2 Parámetros Comida 2 Cálculo Modelo 1-PDR 2 Cálculo Modelo 2-PDR 2 Variables t (1/2) = 79.05 t (1/2) = 85.12 t (1/2) = 85.12 t lag = 55.42 t lag = -36.31 t lag = -36.31 GEC = 3.64 GEC = GEC = 3.64 Error = 4.4559 Error = 3.6093 Error = 3.6093 Parámetros Comida 3 Parámetros Comida 3 Cálculo Modelo 1-PDR 3 Cálculo Modelo 2-PDR 3 Variables t (1/2) = 87.81 t (1/2) = 94.13 t (1/2) = 94.13 t lag = 60.72 t lag = -36.87 t lag = -36.87 GEC = 3.69 GEC = GEC = 3.69 Error = 5.8515 Error = 5.8155 Error = 5.8155 Parámetros Comida 4 Parámetros Comida 4 Cálculo Modelo 1-PDR 4 Cálculo Modelo 2-PDR 4 Variables t (1/2) = 68.81 t (1/2) = 72.68 t (1/2) = 72.68 t lag = 38.63 t lag = -33.73 t lag = -33.73 GEC = 3.80 GEC = GEC = 3.80 Error = 2.7996 Error = 2.4395 Error = 2.4395 Cuestionario de síntomas Plenitud Postprandial Distensión en Abdomen Superior Saciedad Precoz Dolor/Molestias en Abdomen Superior Nauseas Comida 1 0 0 0 0 0 Comida 2 0 0 0 0 0 Comida 3 1 0 0 0 0 Comida 4 1 0 0 0 0 ' -XYZX'POQ!0YWd`!a\Z!`Xp\Wd!AN! ! ! ! ! ! ?! 3%3;%*>)10"1TYPE THE DOCUMENT TITLE! ! 248 Nombre: Sujeto 8 Número: 8 Peso (Kg.): 70 Talla (m.): 1.70 Sexo: Femenino IMC (Kg/m2): 24.2 BSA (m2): 1.8257 Edad (años): 23 Parámetros Volumen (ml.) Modelo Error t ! (min.) t lag (min.) GEC (min.) 200 2 3.3120 79.10 35.17 3.77 400 2 0.8673 46.72 -25.93 3.88 600 2 1.2714 60.14 -28.87 3.93 800 2 5.0686 37.20 -23.43 3.90 Parámetros Comida 1 Parámetros Comida 1 Cálculo Modelo 1-PDR 1 Cálculo Modelo 2-PDR 1 Variables t (1/2) = 65.67 t (1/2) = 79.10 t (1/2) = 79.10 t lag = 34.95 t lag = 35.17 t lag = 35.17 GEC = 3.77 GEC = GEC = 3.77 Error = 7.2878 Error = 3.3120 Error = 3.3120 Parámetros Comida 2 Parámetros Comida 2 Cálculo Modelo 1-PDR 2 Cálculo Modelo 2-PDR 2 Variables t (1/2) = 35.35 t (1/2) = 46.72 t (1/2) = 46.72 t lag = -0.13 t lag = -25.93 t lag = -25.93 GEC = 3.88 GEC = GEC = 3.88 Error = 10.3329 Error = 0.8673 Error = 0.8673 Parámetros Comida 3 Parámetros Comida 3 Cálculo Modelo 1-PDR 3 Cálculo Modelo 2-PDR 3 Variables t (1/2) = 40.90 t (1/2) = 60.14 t (1/2) = 60.14 t lag = 6.30 t lag = -28.87 t lag = -28.87 GEC = 3.93 GEC = GEC = 3.93 Error = 21.0661 Error = 1.2714 Error = 1.2714 Parámetros Comida 4 Parámetros Comida 4 Cálculo Modelo 1-PDR 4 Cálculo Modelo 2-PDR 4 Variables t (1/2) = 31.64 t (1/2) = 37.20 t (1/2) = 37.20 t lag = -4.43 t lag = -23.43 t lag = -23.43 GEC = 3.90 GEC = GEC = 3.90 Error = 7.9283 Error = 5.0686 Error = 5.0686 Cuestionario de síntomas Plenitud Postprandial Distensión en Abdomen Superior Saciedad Precoz Dolor/Molestias en Abdomen Superior Nauseas Comida 1 0 0 0 0 0 Comida 2 0 0 0 0 0 Comida 3 0 0 0 0 0 Comida 4 0 0 0 0 0 ! -XYZX'P4Q!0YWd`!a\Z!`Xp\Wd!FN! ! ! ! ! ! !TYPE THE DOCUMENT TITLE1#'@*/! A! ! 249 Nombre: Sujeto 9 Número: 9 Peso (Kg.): 79 Talla (m.): 1.76 Sexo: Masculino IMC (Kg/m2): 25.5 BSA (m2): 1.9754 Edad (años): 22 Parámetros Volumen (ml.) Modelo Error t ! (min.) t lag (min.) GEC (min.) 200 2 1.1201 75.73 35.64 3.68 400 2 7.0450 89.71 -34.42 3.61 600 2 8.9192 76.96 -31.99 3.83 800 2 7.4865 52.02 -29.38 3.85 Parámetros Comida 1 Parámetros Comida 1 Cálculo Modelo 1-PDR 1 Cálculo Modelo 2-PDR 1 Variables t (1/2) = 66.57 t (1/2) = 75.73 t (1/2) = 75.73 t lag = 36.00 t lag = 35.64 t lag = 35.64 GEC = 3.68 GEC = GEC = 3.68 Error = 2.2809 Error = 1.1201 Error = 1.1201 Parámetros Comida 2 Parámetros Comida 2 Cálculo Modelo 1-PDR 2 Cálculo Modelo 2-PDR 2 Variables t (1/2) = 65.02 t (1/2) = 89.71 t (1/2) = 89.71 t lag = 34.20 t lag = -34.42 t lag = -34.42 GEC = 3.61 GEC = GEC = 3.61 Error = 16.2564 Error = 7.0450 Error = 7.0450 Parámetros Comida 3 Parámetros Comida 3 Cálculo Modelo 1-PDR 3 Cálculo Modelo 2-PDR 3 Variables t (1/2) = 51.60 t (1/2) = 76.96 t (1/2) = 76.96 t lag = 18.69 t lag = -31.99 t lag = -31.99 GEC = 3.83 GEC = GEC = 3.83 Error = 27.5924 Error = 8.9192 Error = 8.9192 Parámetros Comida 4 Parámetros Comida 4 Cálculo Modelo 1-PDR 4 Cálculo Modelo 2-PDR 4 Variables t (1/2) = 50.06 t (1/2) = 52.02 t (1/2) = 52.02 t lag = 17.77 t lag = -29.38 t lag = -29.38 GEC = 3.85 GEC = GEC = 3.85 Error = 8.6212 Error = 7.4865 Error = 7.4865 Cuestionario de síntomas Plenitud Postprandial Distensión en Abdomen Superior Saciedad Precoz Dolor/Molestias en Abdomen Superior Nauseas Comida 1 0 0 0 0 0 Comida 2 0 0 0 0 0 Comida 3 0 0 0 0 0 Comida 4 0 0 0 0 0 ! -XYZX'PCQ!0YWd`!a\Z!`Xp\Wd!.J!! ! ! ! ! ! ?! 3%3;%*>)10"1TYPE THE DOCUMENT TITLE! ! 250 Nombre: Sujeto 10 Número: 10 Peso (Kg.): 77.8 Talla (m.): 1.73 Sexo: Masculino IMC (Kg/m2): 26.0 BSA (m2): 1.9459 Edad (años): 21 Parámetros Volumen (ml.) Modelo Error t ! (min.) t lag (min.) GEC (min.) 200 2 1.8173 56.84 29.83 4.05 400 2 4.9782 59.57 -31.59 3.92 600 2 4.3663 62.55 -31.46 3.97 800 2 1.6609 46.83 -27.37 3.92 Parámetros Comida 1 Parámetros Comida 1 Cálculo Modelo 1-PDR 1 Cálculo Modelo 2-PDR 1 Variables t (1/2) = 54.04 t (1/2) = 56.84 t (1/2) = 56.84 t lag = 31.21 t lag = 29.83 t lag = 29.83 GEC = 4.05 GEC = GEC = 4.05 Error = 2.4680 Error = 1.8173 Error = 1.8173 Parámetros Comida 2 Parámetros Comida 2 Cálculo Modelo 1-PDR 2 Cálculo Modelo 2-PDR 2 Variables t (1/2) = 56.97 t (1/2) = 59.57 t (1/2) = 59.57 t lag = 27.86 t lag = -31.59 t lag = -31.59 GEC = 3.92 GEC = GEC = 3.92 Error = 6.2345 Error = 4.9782 Error = 4.9782 Parámetros Comida 3 Parámetros Comida 3 Cálculo Modelo 1-PDR 3 Cálculo Modelo 2-PDR 3 Variables t (1/2) = 57.92 t (1/2) = 62.55 t (1/2) = 62.55 t lag = 25.99 t lag = -31.46 t lag = -31.46 GEC = 3.97 GEC = GEC = 3.97 Error = 5.2037 Error = 4.3663 Error = 4.3663 Parámetros Comida 4 Parámetros Comida 4 Cálculo Modelo 1-PDR 4 Cálculo Modelo 2-PDR 4 Variables t (1/2) = 43.34 t (1/2) = 46.83 t (1/2) = 46.83 t lag = 9.13 t lag = -27.37 t lag = -27.37 GEC = 3.92 GEC = GEC = 3.92 Error = 2.5617 Error = 1.6609 Error = 1.6609 Cuestionario de síntomas Plenitud Postprandial Distensión en Abdomen Superior Saciedad Precoz Dolor/Molestias en Abdomen Superior Nauseas Comida 1 1 0 0 0 0 Comida 2 1 0 0 0 0 Comida 3 1 0 0 0 0 Comida 4 2 0 0 0 0 ! -XYZX'PJQ!0YWd`!a\Z!`Xp\Wd!4GN! ! ! ! ! ! !TYPE THE DOCUMENT TITLE1#'@*/! A! ! 251 Nombre: Sujeto 11 Número: 11 Peso (Kg.): 68.2 Talla (m.): 1.60 Sexo: Femenino IMC (Kg/m2): 26.6 BSA (m2): 1.7575 Edad (años): 25 Parámetros Volumen (ml.) Modelo Error t ! (min.) t lag (min.) GEC (min.) 200 1 5.5141 50.99 27.38 4.21 400 2 1.7390 66.96 -32.40 3.69 600 2 7.4611 94.25 -34.57 3.83 800 2 1.2029 68.98 -30.49 3.41 Parámetros Comida 1 Parámetros Comida 1 Cálculo Modelo 1-PDR 1 Cálculo Modelo 2-PDR 1 Variables t (1/2) = 50.99 t (1/2) = 53.74 t (1/2) = 50.99 t lag = 27.38 t lag = 26.07 t lag = 27.38 GEC = 4.21 GEC = GEC = 4.21 Error = 5.5141 Error = 5.6358 Error = 5.5141 Parámetros Comida 2 Parámetros Comida 2 Cálculo Modelo 1-PDR 2 Cálculo Modelo 2-PDR 2 Variables t (1/2) = 62.01 t (1/2) = 66.96 t (1/2) = 66.96 t lag = 30.72 t lag = -32.40 t lag = -32.40 GEC = 3.69 GEC = GEC = 3.69 Error = 1.9852 Error = 1.7390 Error = 1.7390 Parámetros Comida 3 Parámetros Comida 3 Cálculo Modelo 1-PDR 3 Cálculo Modelo 2-PDR 3 Variables t (1/2) = 63.11 t (1/2) = 94.25 t (1/2) = 94.25 t lag = 31.99 t lag = -34.57 t lag = -34.57 GEC = 3.83 GEC = GEC = 3.83 Error = 27.6166 Error = 7.4611 Error = 7.4611 Parámetros Comida 4 Parámetros Comida 4 Cálculo Modelo 1-PDR 4 Cálculo Modelo 2-PDR 4 Variables t (1/2) = 45.02 t (1/2) = 68.88 t (1/2) = 68.88 t lag = 11.07 t lag = -30.49 t lag = -30.49 GEC = 3.41 GEC = GEC = 3.41 Error = 9.7755 Error = 1.2029 Error = 1.2029 Cuestionario de síntomas Plenitud Postprandial Distensión en Abdomen Superior Saciedad Precoz Dolor/Molestias en Abdomen Superior Nauseas Comida 1 1 1 0 0 0 Comida 2 1 1 0 0 0 Comida 3 2 1 0 0 0 Comida 4 2 2 1 0 0 ! -XYZX'PPQ!0YWd`!a\Z!`Xp\Wd!44N! ! ! ! ! ! ?! 3%3;%*>)10"1TYPE THE DOCUMENT TITLE! ! 252 Nombre: Sujeto 12 Número: 12 Peso (Kg.): 73 Talla (m.): 1.68 Sexo: Femenino IMC (Kg/m2): 25.9 BSA (m2): 1.8586 Edad (años): 25 Parámetros Volumen (ml.) Modelo Error t ! (min.) t lag (min.) GEC (min.) 200 2 7.2865 120.52 65.48 3.17 400 2 5.1356 94.51 -34.81 3.63 600 2 4.4011 68.94 -31.28 3.75 800 2 5.8781 74.56 -34.01 3.59 Parámetros Comida 1 Parámetros Comida 1 Cálculo Modelo 1-PDR 1 Cálculo Modelo 2-PDR 1 Variables t (1/2) = 84.11 t (1/2) = 120.52 t (1/2) = 120.52 t lag = 56.24 t lag = 65.48 t lag = 65.48 GEC = 3.17 GEC = GEC = 3.17 Error = 12.3848 Error = 7.2865 Error = 7.2865 Parámetros Comida 2 Parámetros Comida 2 Cálculo Modelo 1-PDR 2 Cálculo Modelo 2-PDR 2 Variables t (1/2) = 65.46 t (1/2) = 94.51 t (1/2) = 94.51 t lag = 34.71 t lag = -34.81 t lag = -34.81 GEC = 3.63 GEC = GEC = 3.63 Error = 17.1637 Error = 5.1356 Error = 5.1356 Parámetros Comida 3 Parámetros Comida 3 Cálculo Modelo 1-PDR 3 Cálculo Modelo 2-PDR 3 Variables t (1/2) = 52.29 t (1/2) = 68.94 t (1/2) = 68.94 t lag = 19.49 t lag = -31.28 t lag = -31.28 GEC = 3.75 GEC = GEC = 3.75 Error = 12.6510 Error = 4.4011 Error = 4.4011 Parámetros Comida 4 Parámetros Comida 4 Cálculo Modelo 1-PDR 4 Cálculo Modelo 2-PDR 4 Variables t (1/2) = 70.26 t (1/2) = 74.56 t (1/2) = 74.56 t lag = 40.25 t lag = -34.01 t lag = -34.01 GEC = 3.59 GEC = GEC = 3.59 Error = 6.8122 Error = 5.8781 Error = 5.8781 Cuestionario de síntomas Plenitud Postprandial Distensión en Abdomen Superior Saciedad Precoz Dolor/Molestias en Abdomen Superior Nauseas Comida 1 0 0 0 0 0 Comida 2 0 0 0 0 0 Comida 3 0 0 0 0 0 Comida 4 1 0 0 0 0 ! -XYZX'PEQ!0YWd`!a\Z!`Xp\Wd!49N! ! ! ! ! ! !TYPE THE DOCUMENT TITLE1#'@*/! A! ! 253 Nombre: Sujeto 13 Número: 13 Peso (Kg.): 99 Talla (m.): 1.80 Sexo: Masculino IMC (Kg/m2): 30.6 BSA (m2): 2.2502 Edad (años): 22 Parámetros Volumen (ml.) Modelo Error t ! (min.) t lag (min.) GEC (min.) 200 2 6.9308 50.86 23.11 4.14 400 2 5.8190 47.76 -28.56 3.88 600 2 6.7441 55.75 -29.33 3.90 800 2 1.4683 38.94 -24.06 3.88 Parámetros Comida 1 Parámetros Comida 1 Cálculo Modelo 1-PDR 1 Cálculo Modelo 2-PDR 1 Variables t (1/2) = 48.62 t (1/2) = 50.86 t (1/2) = 50.86 t lag = 24.39 t lag = 23.11 t lag = 23.11 GEC = 4.14 GEC = GEC = 4.14 Error = 8.1334 Error = 6.9308 Error = 6.9308 Parámetros Comida 2 Parámetros Comida 2 Cálculo Modelo 1-PDR 2 Cálculo Modelo 2-PDR 2 Variables t (1/2) = 45.84 t (1/2) = 47.76 t (1/2) = 47.76 t lag = 15.36 t lag = -28.56 t lag = -28.56 GEC = 3.88 GEC = GEC = 3.88 Error = 6.4485 Error = 5.8190 Error = 5.8190 Parámetros Comida 3 Parámetros Comida 3 Cálculo Modelo 1-PDR 3 Cálculo Modelo 2-PDR 3 Variables t (1/2) = 48.69 t (1/2) = 55.75 t (1/2) = 55.75 t lag = 15.32 t lag = -29.33 t lag = -29.33 GEC = 3.90 GEC = GEC = 3.90 Error = 8.4398 Error = 6.7441 Error = 6.7441 Parámetros Comida 4 Parámetros Comida 4 Cálculo Modelo 1-PDR 4 Cálculo Modelo 2-PDR 4 Variables t (1/2) = 33.07 t (1/2) = 38.94 t (1/2) = 38.94 t lag = -2.78 t lag = -24.06 t lag = -24.06 GEC = 3.88 GEC = GEC = 3.88 Error = 4.4055 Error = 1.4683 Error = 1.4683 Cuestionario de síntomas Plenitud Postprandial Distensión en Abdomen Superior Saciedad Precoz Dolor/Molestias en Abdomen Superior Nauseas Comida 1 0 0 0 0 0 Comida 2 0 0 0 0 0 Comida 3 1 0 0 0 0 Comida 4 1 0 0 0 0 ! -XYZX'PBQ!0YWd`!a\Z!`Xp\Wd!4HN! ! ! ! ! ! ?! 3%3;%*>)10"1TYPE THE DOCUMENT TITLE! ! 254 Nombre: Sujeto 14 Número: 14 Peso (Kg.): 96 Talla (m.): 1.83 Sexo: Masculino IMC (Kg/m2): 28.7 BSA (m2): 2.2278 Edad (años): 22 Parámetros Volumen (ml.) Modelo Error t ! (min.) t lag (min.) GEC (min.) 200 1 6.8283 84.42 63.19 3.62 400 2 3.8651 64.00 -31.80 3.80 600 2 10.1214 75.63 -33.16 3.70 800 2 3.7654 73.90 -32.15 3.73 Parámetros Comida 1 Parámetros Comida 1 Cálculo Modelo 1-PDR 1 Cálculo Modelo 2-PDR 1 Variables t (1/2) = 84.42 t (1/2) = 91.46 t (1/2) = 84.42 t lag = 63.19 t lag = 62.43 t lag = 63.19 GEC = 3.62 GEC = GEC = 3.62 Error = 6.8283 Error = 7.8024 Error = 6.8283 Parámetros Comida 2 Parámetros Comida 2 Cálculo Modelo 1-PDR 2 Cálculo Modelo 2-PDR 2 Variables t (1/2) = 59.41 t (1/2) = 64.00 t (1/2) = 64.00 t lag = 27.72 t lag = -31.80 t lag = -31.80 GEC = 3.80 GEC = GEC = 3.80 Error = 4.3738 Error = 3.8651 Error = 3.8651 Parámetros Comida 3 Parámetros Comida 3 Cálculo Modelo 1-PDR 3 Cálculo Modelo 2-PDR 3 Variables t (1/2) = 63.16 t (1/2) = 75.63 t (1/2) = 75.63 t lag = 32.05 t lag = -33.16 t lag = -33.16 GEC = 3.70 GEC = GEC = 3.70 Error = 13.6267 Error = 10.1214 Error = 10.1214 Parámetros Comida 4 Parámetros Comida 4 Cálculo Modelo 1-PDR 4 Cálculo Modelo 2-PDR 4 Variables t (1/2) = 55.62 t (1/2) = 73.90 t (1/2) = 73.90 t lag = 23.34 t lag = -32.15 t lag = -32.15 GEC = 3.73 GEC = GEC = 3.73 Error = 12.2700 Error = 3.7654 Error = 3.7654 Cuestionario de síntomas Plenitud Postprandial Distensión en Abdomen Superior Saciedad Precoz Dolor/Molestias en Abdomen Superior Nauseas Comida 1 0 0 0 0 0 Comida 2 1 0 0 0 0 Comida 3 1 0 0 0 0 Comida 4 2 0 0 0 0 ! -XYZX'PLQ!0YWd`!a\Z!`Xp\Wd!4:N! ! ! ! ! ! !TYPE THE DOCUMENT TITLE1#'@*/! A! ! 255 Nombre: Sujeto 15 Número: 15 Peso (Kg.): 95 Talla (m.): 1.84 Sexo: Femenino IMC (Kg/m2): 28.1 BSA (m2): 2.2201 Edad (años): 21 Parámetros Volumen (ml.) Modelo Error t ! (min.) t lag (min.) GEC (min.) 200 2 2.3308 68.80 26.10 3.70 400 2 8.5724 59.70 -29.59 3.73 600 2 1.0095 61.65 -30.41 3.87 800 2 2.1961 46.94 -29.06 4.12 Parámetros Comida 1 Parámetros Comida 1 Cálculo Modelo 1-PDR 1 Cálculo Modelo 2-PDR 1 Variables t (1/2) = 58.74 t (1/2) = 68.80 t (1/2) = 68.80 t lag = 26.95 t lag = 26.10 t lag = 26.10 GEC = 3.70 GEC = GEC = 3.70 Error = 4.1930 Error = 2.3308 Error = 2.3308 Parámetros Comida 2 Parámetros Comida 2 Cálculo Modelo 1-PDR 2 Cálculo Modelo 2-PDR 2 Variables t (1/2) = 47.34 t (1/2) = 59.70 t (1/2) = 59.70 t lag = 13.76 t lag = -29.59 t lag = -29.59 GEC = 3.73 GEC = GEC = 3.73 Error = 13.9889 Error = 8.5724 Error = 8.5724 Parámetros Comida 3 Parámetros Comida 3 Cálculo Modelo 1-PDR 3 Cálculo Modelo 2-PDR 3 Variables t (1/2) = 51.66 t (1/2) = 61.65 t (1/2) = 61.65 t lag = 18.76 t lag = -30.41 t lag = -30.41 GEC = 3.87 GEC = GEC = 3.87 Error = 4.8229 Error = 1.0095 Error = 1.0095 Parámetros Comida 4 Parámetros Comida 4 Cálculo Modelo 1-PDR 4 Cálculo Modelo 2-PDR 4 Variables t (1/2) = 44.93 t (1/2) = 46.94 t (1/2) = 46.94 t lag = 18.11 t lag = -29.06 t lag = -29.06 GEC = 4.12 GEC = GEC = 4.12 Error = 2.9247 Error = 2.1961 Error = 2.1961 Cuestionario de síntomas Plenitud Postprandial Distensión en Abdomen Superior Saciedad Precoz Dolor/Molestias en Abdomen Superior Nauseas Comida 1 0 0 0 0 1 Comida 2 0 0 0 0 0 Comida 3 0 0 1 0 1 Comida 4 2 0 2 0 1 ! -XYZX'PIQ!0YWd`!a\Z!`Xp\Wd!45N! ! ! ! ! !